References of "Stevenaert, Achille"
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See detailIntrasellar Arachnoïd Cysts: Diagnosis, Management, and Pathophysiology.
Dubuisson, Annie ULg; Martin, Didier ULg; Bruggeman, L. et al

Conference (1995, April 22)

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See detailTraitement préchirurgical par octréolide dans l'acromégalie.
Stevenaert, Achille ULg; Lenelle, Jacques ULg; Martin, Didier ULg et al

Conference (1995, March 11)

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See detailIncreased prevalence of colonic adenomas in acromegalics patiens
Delhougne, B.; Deneux, C.; Abs, R. et al

in Belgian week of gastroenterology : Knokke, March 16th-18th 1995 - Abstract book (1995, March)

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See detailCabergoline in prolactinomen.
Abs, R.; Verhaert, G.; Demez, Pierre ULg et al

in Tijdschrift voor Geneeskunde (1995), 51

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See detailPresurgical Octreotide Treatment in Acromegaly : does it improve surgical cure rate?
Stevenaert, Achille ULg; Lenelle, Jacques ULg; Martin, Didier ULg et al

in 10th European Congress of Neurosurgery - Abstract book (1995)

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See detailThe treatment of Growth Hormone Deficiency in adults : the 148 belgian patients
Beckers, Albert ULg; Moreau, L.; Mockel, J. et al

in The Endocrine Society : Annual meeting, Washington DC, June 1995 (1995)

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See detailTraitement du prolactinome : apport de la cabergoline
Louis, O.; Abs, R.; Stevenaert, Achille ULg et al

in Annales d'Endocrinologie (1995), 56(4), 352

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See detailPrévalence des polypes coliques chez l'acromégale, étude coloscopique de 80 patients
Laurent-Puig, P.; Deneux, C.; Delhougne, B. et al

in Journées Francophones de pathologie digestive - Abstract book (1995)

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See detailPresurgical Octreotide Treatment in Acromegaly
Stevenaert, Achille ULg; Beckers, Albert ULg

in Acta Neurochirurgica (1995), 133

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See detailIncreased prevalence of colonic adenomas acromegalic patients
Delhougne, B.; Deneux, C.; Abs, R. et al

in Fourth Meeting of the Belgian Endocrine Society : 19 november 1994 - Abstract book (1994, November 19)

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See detailVariable regions of chromosome 11 loss in different pathological tissues of a patient with the multiple endocrine neoplasia type I syndrome.
Beckers, Albert ULg; Abs, R.; Reyniers, E. et al

in Journal of Clinical Endocrinology and Metabolism (1994), 79(5), 1498-1502

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant inherited disorder characterized by nodular proliferation of the parathyroid glands and tumors of the anterior pituitary gland, the ... [more ▼]

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant inherited disorder characterized by nodular proliferation of the parathyroid glands and tumors of the anterior pituitary gland, the endocrine pancreas, and the neuroendocrine cell system of the gut. Loss of the putative tumor suppressor effect of the MEN1 gene is probably responsible for the development of MEN1-associated tumors. We report here a genetic study of a female MEN1 patient with the association of nodular hyperplasia of two parathyroid glands, an insulinoma, multiple duodenal gastrinomas, a prolactinoma, and a gastric carcinoid. We performed loss of heterozygosity (LOH) studies of chromosome 11 on all affected tissues except the insulinoma. Allelic losses of chromosome 11 were detected in several tumors, but the chromosomal regions of LOH were different, suggesting that different somatic mutational events are involved in the pathogenesis of these tumors. LOH of chromosome 11 was also detected in the prolactinoma of this patient, which indicates that the MEN1 gene has a tumor suppressor effect in the pituitary. [less ▲]

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See detailDramatic improvement of severe dilated cardiomyopathy in an acromegalic patient after treatment with octreotide and trans-sphenoidal surgery.
Legrand, Victor ULg; Beckers, Albert ULg; Pham, V. T. et al

in European Heart Journal (1994), 15(9), 1286-9

Severe congestive heart failure developed in an acromegalic patient, and was successfully treated with octreotide followed by trans-sphenoidal surgery. Clinical, hormonal echocardiographic and ... [more ▼]

Severe congestive heart failure developed in an acromegalic patient, and was successfully treated with octreotide followed by trans-sphenoidal surgery. Clinical, hormonal echocardiographic and haemodynamic findings as well as histological heart examination before and after treatment revealed that over-production of growth hormone may induce the myocardial cell degeneration responsible for mechanical heart dysfunction. In addition, this unique example demonstrates the reversibility of myocardial damage following octreotide and trans-sphenoidal surgery, leading to significant improvement in cardiac function with minimal diastolic dysfunction and moderate interstitial fibrosis. [less ▲]

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See detailRadiation-Induced Myelopathy and Vertebral Necrosis
Martin, Didier ULg; Delacollette, Mireille ULg; Collignon, Jacques ULg et al

in Neuroradiology (1994), 36(5), 405-7

Radiation-induced myelopathy is often a diagnosis of exclusion. In addition to the classic criteria needed to support the diagnosis, the presence of another radiation-induced lesion, such as aseptic ... [more ▼]

Radiation-induced myelopathy is often a diagnosis of exclusion. In addition to the classic criteria needed to support the diagnosis, the presence of another radiation-induced lesion, such as aseptic vertebral necrosis, is useful to confirm the cause of the spinal cord lesion. [less ▲]

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See detailAutonomously functioning thyroid nodules in a patient with a thyrotropin-secreting pituitary adenoma: possible cause--effect relationship.
Abs, R.; Stevenaert, Achille ULg; Beckers, Albert ULg

in European Journal of Endocrinology (1994), 131(4), 355-8

A 51-year-old female patient with long-standing hyperthyroidism due to a thyrotropin-secreting pituitary adenoma is reported, who became thyrotoxic again shortly after successful pituitary surgery ... [more ▼]

A 51-year-old female patient with long-standing hyperthyroidism due to a thyrotropin-secreting pituitary adenoma is reported, who became thyrotoxic again shortly after successful pituitary surgery. Functional testing and scintigraphy suggested the diagnosis of autonomous functioning thyroid nodules, which was confirmed by pathological examination of the resected thyroid tissue. This is the first report revealing the transition from a pituitary-dependent to a thyroid-dependent hyperthyroidism. Autonomous functioning thyroid nodules are, however, considered an intrinsic thyroid defect. In similarity with other disorders, in which trophic hormones may induce an autonomous secretion by the target gland, this report opens the possibility that a humoral factor may play a role in the development of autonomous functioning thyroid nodules. [less ▲]

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See detailPrévalence des polypes coliques chez l'acromégale. Etude coloscopique de 80 patients
Deneux, c; Delhougne, B.; Beckers, Albert ULg et al

in XIIème congrès de la Société Française d'endocrinologie - Abstract book (1994)

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See detailFamilial aspects in acromegaly
Verloes, Alain ULg; Beckers, Albert ULg; Pétrossians, E. et al

in 26th Annual meeting of European society of Human Genetics. Abstract book (1994)

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See detailStabilité du rachis cervical lors de l'abord antérieur des myélopathies cervicarthrosiques
Lenelle, Jacques ULg; Bex, V.; Dubuisson, Annie ULg et al

Conference (1993, September 24)

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See detailPresurgical Octreotide Treatment in Acromegaly
Stevenaert, Achille ULg; Beckers, Albert ULg

in Acta Endocrinologica (1993), 129(1), 18-20

The effects of octreotide pretreatment before surgery were assessed in 48 acromegalic patients who underwent trans-sphenoidal surgery to remove pituitary adenoma, and compared with 107 patients who did ... [more ▼]

The effects of octreotide pretreatment before surgery were assessed in 48 acromegalic patients who underwent trans-sphenoidal surgery to remove pituitary adenoma, and compared with 107 patients who did not receive octreotide before surgery. Pretreated patients received octreotide 100 micrograms, thrice daily for 3 to 6 weeks (group 1), or 100 to 500 micrograms, thrice daily for 3 to 39 months (group 2). Total remission of symptoms was seen in 54%. Partial remission of symptoms occurred in 39%. Octreotide pretreatment reduced plasma GH levels by > or = 50% in all patients. GH levels were reduced to < 2 micrograms/1 in 3/14 group 1 cases and 13/34 group 2 cases. Tumour shrinkage occurred in 56.5% of patients. Marked tumour shrinkage (> 25%) occurred in more group 2 patients (10/32 vs 1/14). The tumour was soft in 39 patients, firm in 6 and hard in 3 cases. Soft consistency aided surgical removal of adenomas. Remission was greater in enclosed adenomas than in invasive tumours in both octreotide pretreated and nonpretreated acromegalics (76 vs 30%). Remission was more likely if the adenoma was less than 16 mm. Remission rate was significantly greater (p < 0.05) in all octreotide pretreated than in untreated patients for enclosed adenoma, but not for invasive adenoma. Octretide pretreatment can be recommended for three to four months prior to surgery. [less ▲]

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