References of "Scippo, Marie-Louise"
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See detailDETERMINATION OF TRIFLURALIN RESIDUES IN CULTURED CATFISH AND WATER.
Nguyen Quoc, Thinh; Tran Minh, Phu; Do Thi Thanh, Huong et al

Poster (2011)

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See detailThe Use of Phages and Aptamers as Alternatives to Antibodies in Medical and Food Diagnostics.
Mehta, Jaytry; Van Dorst, Bieke; Devriese, Lisa et al

in Komorowska, Malgorzata Anna; Olsztynska-Janus, Sylwia (Eds.) Biomedical Engineering, Trends, Research and Technologies (2011)

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See detailFaut-il interdire le Bisphenol A dans les récipients destinés à contenir des aliments ?
Scippo, Marie-Louise ULg

in Culture, le magazine culturel en ligne de l'Université de Liège - DOSSIER/ Controverses scientifiques - http://culture.ulg.ac.be/jcms/prod_494506/dossier/-controverses-scientifiques?section=cdu_5047 (2011)

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See detailPotential of an in vitro toolbox combined with exposure data as a first step for the risk assessment of dietary chemical contaminants
Ribonnet, Laurence; Van Der Heiden, Edwige ULg; Nobels, Ingrid et al

in Food Additives & Contaminants (2011), 28(9), 1136-1158

In vitro risk assessment of dietary contaminants has become a priority in human food safety. This paper proposes an in vitro approach associating different complementary tools in an original toolbox and ... [more ▼]

In vitro risk assessment of dietary contaminants has become a priority in human food safety. This paper proposes an in vitro approach associating different complementary tools in an original toolbox and aims to improve the assessment of the toxicological impact of dietary contaminants at realistic human exposure levels, with a special focus on the intestinal compartment. The system is based on the use of four complementary cellular tools, namely stress gene induction in transgenic strains of Escherichia coli, modulation of the activity of key biotransformation enzymes (cytochrome P-450 (CYP) 1A1 and 3A4) in a human intestinal cell line, and activation of aryl hydrocarbon receptor (AhR) and oestrogenic receptor (ER)-dependent genes in agonistic and antagonistic assays with luciferase reporter cells. It was applied to four chosen model molecules: ochratoxin A (OTA) and deoxynivalenol (DON), two common food-borne mycotoxins, and imazalil (IMA) and benomyl (BEN), two fungicides widely occurring in foodstuffs. All these assays were performed at or around a realistic intestinal concentration, determined through a deterministic approach based on the calculation of a theoretical maximum daily intake (TMDI). Using the four model molecules, it is clearly highlighted that induction of CYP1A1 activity and inhibition of CYP3A4 activity occurred in Caco-2 cells at a realistic intestinal concentration of IMA. Furthermore, some bacterial stress genes were induced in a range of realistic concentrations, following exposure to DON and IMA. In addition, BEN clearly provoked an ER agonistic activity in a human oestrogen sensitive reporter cell line. All these results are in accordance with the literature, suggesting that the in vitro toolbox constitutes an interesting approach in order to obtain a first 'fingerprint' of dietary contaminants at realistic human exposure for further risk assessment. [less ▲]

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See detailOptimisation of a new two-plate screening method for the detection of antibiotic residues in meat
Dang, Pham Kim; Degand, Guy ULg; Douny, Caroline ULg et al

in International Journal of Food Science & Technology (2011), 46

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See detailNew approach to quantitative analysis of benzo[a]pyrene in food supplements by an immunochemical column test
Beloglazova, Natalia; Goryacheva, Irina; De Saeger, Sarah et al

in Talanta (2011), 85

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See detailIn vitro selection and characterization of DNA aptamers recognizing chloramphenicol
Mehta, Jaytry; Van Dorst, Bieke; Rouah-Martin, Elsa et al

in Journal of Biotechnology (2011), 155

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See detailModulation of CYP1A1 activity by a Ginkgo biloba extract in the human intestinal Caco-2 cells
Ribonnet, Laurence; Callebaut, Alfons; Nobels, Ingrid et al

in Toxicology Letters (2011), 202(3), 193-202

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See detailAntibiotics and pesticides residues in aquaculture products
Scippo, Marie-Louise ULg

Conference (2010, April 28)

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See detailREVISED EU-CRITERIA FOR APPLYING BIOANALYTICAL METHODS FOR SCREENING OF FEED AND FOOD FOR DIOXINS AND DIOXIN-LIKE PCBS.
Hoogenboom, LAP; Hadrich, Johan; Eppe, Gauthier ULg et al

in Organohalogen Compounds (2010), 72

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See detailRemoval of Androgens and Estrogens from Water by Reactive Materials
Kai, Cai; Phillips, D. H.; Elliott, Christian et al

in Journal of Water Resource and Protection (2010), 2(11), 990-993

Nowadays, endocrine disruptor compounds in the water system have become a concern due to the risk of contamination to wild life and humans even at the nanogram level. Excess estrogens and androgens are a ... [more ▼]

Nowadays, endocrine disruptor compounds in the water system have become a concern due to the risk of contamination to wild life and humans even at the nanogram level. Excess estrogens and androgens are a major contributor group of endocrine compounds. Statistical surveys have shown that dairy farms contribute to over 90% of the total estrogens in the UK and US. An analytical system is being developed to assess the efficiency of reactive materials to remove target hormonal contaminants from dairy farm effluent. This can be achieved using reporter gene assays (RGAs) to detect low level steroid hormones. A preliminary study comparing the efficiency of granular activated carbon, zero-valent iron, and organoclay was carried out using bench-scale evaluations in negative control HPLC water. Their potential ability to remove testosterone and 17-β- estradiol spiked at reported environmental levels was measured by androgenic and estrogenic luminescent reporter assay respectively. [less ▲]

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See detailSURVEY ON ANTIBIOTIC USE IN PIG AND CHICKEN PRODUCTION IN RED RIVER DELTA OF VIETNAM.
Pham Kim, Dang; Saegerman, Claude ULg; Vu Dinh, Ton et al

Poster (2010)

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