Location of transcriptional regulatory sequences within the prolactin family genes.; ; et al in Neuroendocrine Perspectives. (1986) ![]() Localisation des séquences régulatrices de la transcription. Application aux gènes de la famille prolactine.; ; et al in Annales d'Endocrinologie (1986), 47 We are studying nucleotide sequences responsible for the regulation of eukaryotic gene expression. Our test system comprises the human genes coding for prolactin (hPRL), growth hormone (hGH-N) and ... [more ▼] We are studying nucleotide sequences responsible for the regulation of eukaryotic gene expression. Our test system comprises the human genes coding for prolactin (hPRL), growth hormone (hGH-N) and placental lactogen (hCS-B). We have cloned these genes and are searching within their sequences for in vitro binding sites of the human glucocorticoid receptor on the hGH-N and hCS-B genes; the in vivo activity of such DNA sequences by assaying hybrid gene expression in transfected cells; in vivo "enhancer" activity of different hPRL gene fragments linked to a marker gene and transfected in cultured cells. [less ▲] Detailed reference viewed: 11 (0 ULg) Location of transcriptional and regulatory sequences within the prolactin family genes; ; et al in Müller, E. E.; McLeod, R. M. (Eds.) Neuroendocrine Perspectives (1986) Detailed reference viewed: 5 (2 ULg) |
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