References of "Saegerman, Claude"
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See detailWATER-BORNE EMERGING ZOONOSE? CASE REPORT ON ERYSIPELAS (ERYSIPELOTHRIX RHUSIOPATHIAE) IN HARBOUR PORPOISES (PHOCOENA PHOCOENA) AND HARBOUR SEAL (PHOCA VITULINA).
Boseret, Géraldine ULg; Saegerman, Claude ULg; Mainil, Jacques ULg et al

Poster (2012, March 26)

An adult female harbour porpoise (Phocoena phocoena) and a juvenile male harbour seal (Phoca vitulina) have been found stranded dead on the Belgian coast in late 2001. As the two bodies were in good ... [more ▼]

An adult female harbour porpoise (Phocoena phocoena) and a juvenile male harbour seal (Phoca vitulina) have been found stranded dead on the Belgian coast in late 2001. As the two bodies were in good condition (CC = 2), necropsy and bacteriological analyses were performed as well as other postmortem investigations. Blood heart and organs (liver, digestive and respiratory tract, lungs, spleen, brain, kidneys) samples have been collected and analyzed. The porpoise showed evidence of septicaemia, and the seal presented lesions of acute enteritis. Pure and abundant growth of a small rod-shaped, Gram-labile bacterium was obtained aerobically and anaerobically on Columbia blood agar from heart blood, mouth, pharynx, lungs, intestine and anus of the porpoise, and from intestine, pharynx, mouth, nose and anus of the seal. The colonies were surrounded by a narrow zone of alpha-hemolysis. Catalase- and peroxydase-tests gave negative results. Rapid ID 32 Strepto (Biomérieux, France) sugar tests identified this isolate as Erysipelothrix rhusiopathiae. E. rhusiopathiae could be therefore considered as the cause of septicaemia on the porpoise as it was present in heart blood and internal organs, and could be associated primary or secondary with the enteritis reported on the seal as the bacterium was isolated in pure culture in the digestive tract. E. rhusiopathiae infections have been reported in captive dolphins and sea lions. This zoonotic pathogen is also involved in human local infections, like the “seal finger”, resulting from captive pinnipeds bites. However, it has not been so far described as systemic pathogens of wild cetaceans and pinnipeds. E. rhusiopathiae could be therefore considered as a potentially emergent pathogen which could have important repercussions on human health, particularly veterinarians, marine mammals rescue teams and zoos. [less ▲]

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See detailRisk assessment of Belgian adults for furan contamination through the food chain
Scholl, Georges ULg; Humblet, Marie-France ULg; Scippo, Marie-Louise ULg et al

in Food Additives & Contaminants (2012), 29(3), 345-353

Risk assessment is an interdisciplinary process used to quantify the risk linked to a hazard. In the present paper it is applied to quantify the risk linked to furan ingestion through the food chain for ... [more ▼]

Risk assessment is an interdisciplinary process used to quantify the risk linked to a hazard. In the present paper it is applied to quantify the risk linked to furan ingestion through the food chain for the Belgian adult population. Two approaches, deterministic and probabilistic, were carried out in parallel. The deterministic method relied on a case study, whereas the probabilistic approach involved statistical distributions of contamination and consumption data to calculate a statistical distribution of the daily intake. First, the deterministic method revealed a low estimated daily intake (EDI) for the average population (380 ng*(kgbw*day)–1) and a huge contribution of coffee consumption to the EDI (55%). Increasing or decreasing the daily coffee consumption by one cup can affect the EDI by about 22%. Afterwards, the probabilistic approach showed that the average population has a low EDI (494 ng*(kgbw*day) 1), and that high contamination levels were only registered in a small proportion of the population. Finally, a comparison of the RfDchronic oral showed that less than 10% of the Belgian population had an EDI above the reference dose proposed by the USEPA; the majority of the population had an EDI 20% below the reference dose. The margin of exposure (MoE) approach indicated that the level of risk related to furan intake through ingestion is low, with a MoE>10,000 for more than 10% of the population and no result < 100. [less ▲]

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See detailAspects épidémiologiques liés à l’émergence du virus Schmallenberg
Saegerman, Claude ULg

Scientific conference (2012, February 17)

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See detailLongitudinal field study on bovine Babesia spp. and Anaplasma phagocytophilum infections during a grazing season in Belgium
Lempereur, Laetitia ULg; Lebrun, Maude; Cuvelier, Pascale et al

in Parasitology Research (2012), 110(4), 1525-1530

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See detailApplication d’une méthodologie fondée sur la multidisciplinarité et la médecine factuelle pour ordonnancer et classer les maladies des animaux producteurs de denrées alimentaires et les zoonoses
Humblet, Marie-France ULg; Vandeputte, Sébastien ULg; Albert, Adelin ULg et al

in Epidémiologie et Santé Animale (2012), 62

Le processus de hiérarchisation présenté dans ce travail repose sur une prise de décision multicritères qui inclut les opinions d’experts multidisciplinaires et des données de médecine factuelle. Cent ... [more ▼]

Le processus de hiérarchisation présenté dans ce travail repose sur une prise de décision multicritères qui inclut les opinions d’experts multidisciplinaires et des données de médecine factuelle. Cent maladies animales et zoonotiques ont été considérées dans l’exercice et cinq catégories regroupant 57 critères ont été prises en compte. Des experts internationaux ont réalisé une pondération intra-catégorie et inter-catégories des critères. L’information correspondant à chaque critère/maladie a été collectée sur base de la médecine factuelle. Un score global pondéré a été calculé pour chaque maladie sur base de deux approches, déterministe et probabiliste. Un classement consécutif des maladies a été établi. Un arbre de classification et de régression a permis de classer les maladies en quatre sous-groupes. Peu de différences ont été observées entre les méthodes déterministe et probabiliste. Cet outil générique et prédictif pourrait être appliqué dans différents contextes et à des maladies affectant d’autres espèces animales [less ▲]

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See detailIs evidence-based medicine so evident in veterinary research and practice? History, obstacles and perspectives.
Vandeweerd, Jean-Michel ULg; Kirschvink, Nathalie; Clegg, Peter et al

in Veterinary Journal (2012), 191(1), 28-34

Evidence-based medicine (EBM) refers to the conscientious, explicit and judicious use of current best evidence from research for the care of an individual patient. The concept of EBM was first described ... [more ▼]

Evidence-based medicine (EBM) refers to the conscientious, explicit and judicious use of current best evidence from research for the care of an individual patient. The concept of EBM was first described in human medicine in the early 1990s and was introduced to veterinary medicine 10 years later. However, it is not clear that the EBM approach promulgated in human medicine can be applied to the same extent to veterinary medicine. EBM has the potential to help veterinarians to make more informed decisions, but obstacles to the implementation of EBM include a lack of high quality patient-centred research, the need for basic understanding of clinical epidemiology by veterinarians, the absence of adequate searching techniques and accessibility to scientific data bases and the inadequacy of EBM tools that can be applied to the busy daily practise of veterinarians. This review describes the development of EBM in the veterinary profession, identifies its advantages and disadvantages and discusses whether and how veterinary surgeons should further adopt the EBM approach of human medicine. [less ▲]

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See detailLe virus Schmallenberg ou l’émergence du premier Orthobunyavirus du sérogroupe Simbu en Europe
Martinelle, Ludovic ULg; Dal Pozzo, Fabiana ULg; Kirschvink, N et al

in Annales de Médecine Vétérinaire (2012), 156(1), 07-24

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See detailEvidence-based early clinical detection of emerging diseases in food animals and zoonoses: two cases.
Saegerman, Claude ULg; Humblet, Marie-France ULg; Porter, Sarah ULg et al

in Veterinary Clinics of North America. Food Animal Practice (2012), 28(1), 121-131

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See detailEstimation du coût d’un réseau d’épidémiosurveillance des maladies animales en Afrique centrale : le cas du réseau tchadien
Ouagal, M; Berkvens, D; Hendrikx, P et al

in Revue scientifique et technique - Office international des épizooties (2012), 31(3), 809-819

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See detailDétection des protéines animales transformées : expérience et perspectives européennes
Plouvier, B; Baeten, V; Maudoux, JP et al

in Revue Scientifique et Technique / Office International des Epizooties = Revista Cientifica y Tecnica / Officina Internacional de Epizootias = Scientific and Technical Review / International Office of Epizootics (2012), 31(3), 1011-1031

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See detailRisk factors associated with bovine tuberculosis and molecular characterization of Mycobacterium bovis strains in urban settings in Niger
Boukary, A. R.; Thys, E.; Rigouts, L. et al

in Transboundary and Emerging Diseases (2012), 59(6), 490-502

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See detailRotenoid content and in vitro acaricidal activity of Tephrosia vogelii leaf extract on the tick Rhipicephalus appendiculatus
Kalume; Losson, Bertrand ULg; Angenot, Luc ULg et al

in Veterinary Parasitology (2012), 190(1-2), 204-209

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See detailEuropean outbreaks of atypical myopathy in grazing horses (2006-2009): Determination of indicators for risk and prognostic factors
Van Galen, Gaby ULg; Saegerman, Claude ULg; Marcilllaud Pitel, Christel et al

in Equine Veterinary Journal (2012), DOI: 10.1111/j.2042-3306.2012.00555.x

Appropriate management of atypical myopathy (AM) requires the establishment of an accurate diagnosis and prognosis. Furthermore, preventive measures to avoid AM need to be refined. The aims of the study ... [more ▼]

Appropriate management of atypical myopathy (AM) requires the establishment of an accurate diagnosis and prognosis. Furthermore, preventive measures to avoid AM need to be refined. The aims of the study were as follows: 1) to improve the diagnosis of AM; 2) to identify prognostic predictors; and 3) to refine recommended preventive measures based on indicators of risk factors. [less ▲]

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See detailFoci report on indigenous Dermacentor reticulatus populations in Belgium and a preliminary study of associated babesiosis pathogens.
Cochez, C.; Lempereur, Laetitia ULg; Madder, Maxime et al

in Medical and Veterinary Entomology (2012), 26(3), 355-358

The occurrence of autochthonous clinical cases of canine and equine babesiosis in Belgium during the last two decades suggests that the vector of the pathogens responsible for these diseases, Dermacentor ... [more ▼]

The occurrence of autochthonous clinical cases of canine and equine babesiosis in Belgium during the last two decades suggests that the vector of the pathogens responsible for these diseases, Dermacentor reticulatus (Ixodida: Ixodidae), may be present in this country. Consequently, evidence for the presence of this tick species in different locations within Belgium was investigated. Four different locations were monitored by flagging in 2010; these included the locations at which D. reticulatus was previously found on a dog in 2009 and on two red deer in 2007. Two different species of tick were identified, Ixodes ricinus (Ixodida: Ixodidae) and D. reticulatus. A total of 282 D. reticulatus adult ticks (98 males, 184 females) were collected from the four sites. Ticks were found mainly from early March until the end of May and a peak in activity was apparent in March. A Babesia spp. (Piroplasmida: Babesiidae) genus-specific polymerase chain reaction test based on the amplification of a fragment of the 18S rRNA gene was used to investigate the potential presence of Babesia spp. All DNA extracts isolated from the total tick samples yielded negative results. Additional studies to accurately determine the distribution and vectorial capacity of this important tick species in Belgium are warranted. [less ▲]

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See detailWild Cervids Are Host for Tick Vectors of Babesia Species with Zoonotic Capability in Belgium
Lempereur, Laetitia ULg; Wirtgen, Marc ULg; Nahayo, Adrien ULg et al

in Vector Borne & Zoonotic Diseases (2012), 12(4), 275-280

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See detailEstimation of furan contamination across the Belgian food chain.
Scholl, Georges ULg; Scippo, Marie-Louise ULg; De Pauw, Edwin ULg et al

in Food Additives & Contaminants. Part A. Chemistry, Analysis, Control, Exposure & Risk Assessment (2012), 29(2), 172-9

This paper provides an estimate of the furan content of Belgian foods. The objective of the study was to achieve the best food chain coverage with a restricted number of samples (n = 496). The geographic ... [more ▼]

This paper provides an estimate of the furan content of Belgian foods. The objective of the study was to achieve the best food chain coverage with a restricted number of samples (n = 496). The geographic distribution, different market chains and labels, and consumption frequencies were taken into account in the construction of the sampling plan. Weighting factors such as contamination levels, consumption frequency and the diversity of food items were applied to set up the model. The very low detection capabilities (CC(beta)) of the analytical methods used (sub-ppb) allowed reporting of 78.2% of the overall dataset above CC(beta) and, in particular, 96.7% for the baby food category. The highest furan levels were found in powdered roasted bean coffee (1912 microg kg(-1)) with a mean of 756 microg kg(-1) for this category. Prepared meat, pasta and rice, breakfast cereals, soups, and baby food also showed high mean furan contents ranging from 16 to 43 microg kg(-1). Comparisons with contamination surveys carried out in other countries pointed out differences for the same food group and therefore contamination levels are related to the geographical origin of food items. [less ▲]

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See detailSeroprevalence and risk factors for brucellosis in a high-risk group of individuals in Bangladesh.
Rahman, A. K. M. Anisur; Dirk, Berkvens; Fretin, David et al

in Foodborne Pathogens and Disease (2012), 9(3), 190-7

Brucellosis is an occupational hazard of livestock farmers, dairy workers, veterinarians, slaughterhouse workers, and laboratory personnel, all of whom are considered to belong to the high-risk ... [more ▼]

Brucellosis is an occupational hazard of livestock farmers, dairy workers, veterinarians, slaughterhouse workers, and laboratory personnel, all of whom are considered to belong to the high-risk occupational group (HROG). A study was undertaken to determine the seroprevalence of brucellosis, identify risk factors associated with brucellosis seropositivity, and detect Brucella at genus level using real-time polymerase chain reaction (PCR) among people in the HROG in the Dhaka division of Bangladesh. A sample of 500 individuals from the HROG was collected from three districts of Dhaka division of Bangladesh. A multiple random effects logistic regression model was used to identify potential risk factors. Two types of real-time PCR methods were applied to detect Brucella genus-specific DNA using serum from seropositive patients. The prevalence of brucellosis based on the three tests was observed to be 4.4% based on a parallel interpretation. The results of the multiple random effects logistic regression analysis with random intercept for district revealed that the odds of brucellosis seropositivity among individuals who had been in contact with livestock for more than 26 years was about 14 times higher as compared to those who had less than 5 years of contact with livestock. In addition, when the contact was with goats, the odds of brucellosis seropositivity were about 60 times higher as compared to when contact was with cattle only. Noticeable variation in brucellosis seropositivity among humans within the three districts was noted. All of the 13 individuals who tested positive for the serological tests were also positive in two types of real-time PCR using the same serum samples. Livestock farmers of brucellosis positive herds had a significantly higher probability to be seropositive for brucellosis. The study emphasized that contact with livestock, especially goats, is a significant risk factor for the transmission of brucellosis among individuals in the HROG. [less ▲]

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See detailRisk factors associated with brucellosis seropositivity among cattle in the central savannah-forest area of Ivory Coast.
Sanogo, Moussa; Abatih, Emmanuel; Thys, Eric et al

in Preventive Veterinary Medicine (2012)

Serological results obtained from 907 serum samples collected from unvaccinated cattle of at least 6 months of age in the savannah-forest region of Ivory Coast were used to investigate risk factors ... [more ▼]

Serological results obtained from 907 serum samples collected from unvaccinated cattle of at least 6 months of age in the savannah-forest region of Ivory Coast were used to investigate risk factors associated with bovine brucellosis seropositivity. Serum samples were tested using the Rose Bengal test (RBT) and indirect enzyme linked immunosorbent assay (iELISA). Using a parallel interpretation, RBT and iELISA results showed that 10.3% (95% confidence interval (CI): 8.4, 12.4) of the cattle had antibodies against Brucella in our study area. The logistic regression analysis indicated that brucellosis seropositivity was associated with age and herd size. Cattle above 5 years of age were found to have a higher chance of being seropositive (odd ratio (OR)=2.8; 95% CI: 1.3, 6.4) compared to cattle under 3 years of age. Similarly, the odd of brucellosis seropositivity for herds with more than 100 cattle was 3.3 (95% CI: 1.2, 8.9) times higher compared to those with less than 50 cattle. [less ▲]

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