References of "Rompen, Eric"
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See detailEarly Implant placement in socket preservations: 12-month results of a prospective case series.
DETHIER, Frédéric ULg; LECLOUX, Geoffrey ULg; ROMPEN, Eric ULg et al

Poster (2012, June)

Objectives: The aim of this study was to evaluate the clinical and histological outcomes of implant placed after socket preservation procedures in the esthetic zone. Implant survival rate and biological ... [more ▼]

Objectives: The aim of this study was to evaluate the clinical and histological outcomes of implant placed after socket preservation procedures in the esthetic zone. Implant survival rate and biological complications were recorded during a follow-up period of 1 year. Materials and methods: A series of 12 patients needing the replacement of a single tooth in the esthetic zone were included in the present study. The hopeless teeth were extracted atraumatically, the sockets were filled with bovine hydroxyapatite (0.25-1mm particles) and the sites were covered with a saddled connective tissue graft. After a healing period of 3 months, biopsies were retrieved in the socket preservation sites and implants were placed. The patients were followed for a period of 1 year. Results: The etiologies of tooth loss were : endodontic (9), caries (1), periodontal (1), and traumatic (1). A total of 12 implants (10 incisors, 2 premolars) were placed on 12 patients (6 men / 6 women) aged from 24 to 61 (42,3 – 11,91). All implant reached an adequate primary stability (> 20N/cm2). 7 out of 12 implants were immediately restored with a temporary crown, and the définitive restorations were successfully placed in all cases. After a follow-up period of 1 year, all implants fulfilled strict success criteria for dental implants with regard to osteointegration, including the absence of peri-implant radiolucency, implant mobility, suppuration, and pain and no further complications occurred. Out of 12 sites only 7 biopsies were retrieved for histological analyses. New bone was found in the apical third of the socket in every specimen, in the mid-third in only 3 specimen and no bone was found in any of the spécimen in the more cervical third of the socket. Conclusion: The results from this prospective case series suggest that early implant placement in extraction socket site seems to display good clinical outcomes despite the incomplete bone regeneration in the socket at 3 months. [less ▲]

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Peer Reviewed
See detailDescription of a ‘soft tissue friendly’ protocol for immediate loading in the esthetic zone: 1 year result of 13 consecutive patients
COMPEYRON, Yoann ULg; LECLOUX, Geoffrey ULg; ROMPEN, Eric ULg et al

Poster (2012, June)

Objectives: Repeted abutment connection and disconnections compromize the connective and epithelial sealing around implant components, leading to peri-implant bone remodeling (Abrahamsson, 1997). Placing ... [more ▼]

Objectives: Repeted abutment connection and disconnections compromize the connective and epithelial sealing around implant components, leading to peri-implant bone remodeling (Abrahamsson, 1997). Placing the definitive abutment at the time of implant placement might be a treatment option to minimize this biological rupture. The aim of this study was to evaluate the effectiveness of pre-shaped zirconium abutments for immediate implant loading in the anterior maxilla. Materials and methods: A total of 13 patients needing the placement of one or several implant in the esthetic zone were treated with Regular Crossfit Bone Level (Straumann) implants. Implants were placed and immediately restored with a pre-shaped zirconium abutments and provisional resin crowns if the primary stability reached at least 20 N/cm2. Implant survival rate, biological and prosthodontic complications as well as peri-implant tissue status (papilla index) were recorded during a follow-up period of 1 year. Results: A total of 14 implants (8 incisors, 1 canines, 5 premolars) placed in 11 patients (4 men / 7 women) aged from 22 to 60 years old (48,5 +/- 11,5) could be assessed for the entire follow-up period. 2 patients dropped out. All implants reached an adequate primary stability (> 20N/cm2) to perform an immediate implant restoration. Straight pre-shaped Zirconium abutment was used in each case. Six implants were placed in socket preservation sites and five implants were placed simultaneously with a GBR. After a follow-up period of 1 year, all implants fulfilled survival criteria for dental implants with regard to osteointegration, including the absence of peri-implant radiolucency, implant mobility, suppuration, and pain. One abutment screw loosening was observed during the provisional period and no abutment fracture occurred. Definitive full ceramic-cemented restorations were successfully performed on each implant after a mean period of 6 months and no further complications occurred. In 11 out of 14 implants, an improvement of the papilla index was observed from baseline to 1 year follow-up whereas 3 implants showed a decrease of this index. Conclusion: The results from this prospective case series suggest that immediately restored implants using a final pre-shaped zirconium abutment in esthetic zone display favorable implant and prosthodontic outcomes and seems to allow an adequate papilla index improvement in most of the cases. [less ▲]

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Peer Reviewed
See detailPatient morbidity after socket preservation using a connective tissue graft versus a bilayer collagen matrix: Preliminary results of a comparative Randomized Control Trial.
FERNANDEZ AYORA, Alberto ULg; VANHOUTTE, Vanessa ULg; LECLOUX, Geoffrey ULg et al

Poster (2012, June)

INTRODUCTION AND AIM: The present randomized controlled trial compared socket preservation procedures using bovine hydroxyapatite (Bio-Oss®, Geistlich, Switzerland) covered with a connective tissue graft ... [more ▼]

INTRODUCTION AND AIM: The present randomized controlled trial compared socket preservation procedures using bovine hydroxyapatite (Bio-Oss®, Geistlich, Switzerland) covered with a connective tissue graft (CT) versus a bilayer collagen membrane (CM) (Mucograft®, Geistlich, Switzerland), placed from buccal to palatal in split-thickness pouches in order to seal the extraction site and to potentially thicken the buccal mucosa. The aim of this present abstract was to evaluate post-operative complications and patient-centered outcomes of the two independent surgical protocols. METHODS: This randomized controlled trial included 26 patients (16 female, 10 male) aged from 20 to 69 years (mean: 42.6, SD: 12). 26 teeth were extracted atraumatically and the 2 distinct surgical protocols were applied randomly. Patients filled out a VAS form 1 week after the surgery to evaluate their level of discomfort and post-operative pain. Drug intakes as well as complications were also recorded. RESULTS: No statistical significant differences were found between the 2 groups in terms of post-operative complications (bleeding) and post-operative pain. The consumption of painkillers after the surgery decreased over time but was similar in the two groups. CONCLUSION: According to the preliminary results of the present RCT, none of both protocols seemed to induce significant post-operative pain and discomfort. There was no difference between the two procedures regarding post-operative complications and patient centered outcomes. [less ▲]

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Peer Reviewed
See detailDental extractions in patients treated with intravenous bisphosphonates and risk of osteonecrosis of jaws.
GAUDIN, Elise ULg; HERION, Francine ULg; ROMPEN, Eric ULg et al

Poster (2012, June)

Aim : Dental extraction remains contra-indicated in patients treated with intravenous (IV) bisphosphonates for oncology reasons because of the high risk of bisphosphonate-related osteonecrosis of the jaw ... [more ▼]

Aim : Dental extraction remains contra-indicated in patients treated with intravenous (IV) bisphosphonates for oncology reasons because of the high risk of bisphosphonate-related osteonecrosis of the jaw (BRONJ). The objective of the present abstract was to present a preventive tooth extraction protocol in patients treated with IV bisphosphonates based on the surgical removal of the alveolar process. The second objective was to identify potential risk factors to develop BRONJ. Material and Methods : 17 patients treated with IV bisphosphonate and needing at least a tooth extraction, were included. A standardized extraction protocol was followed, including alveolectomy of at least 50% of the alveolar process, pre and post-operative antibiotherapy was administrated. The patients were followed for a mean period of 29 months (min:3 -max:62). Results : In all, 17 patients and 22 extraction sites mandible (15), maxilla (7) were involved in the study. No signs of inflamed tissue or necrotic exposed bone in any patient were observed during the follow-up period and the level of comfort for the patient was improved in all cases. Nevertheless, when a careful screening of the healing area was made using a probe, in 4 out of 22 (18,2%) sites, a remaining bone contact was found and appeared to be related location (mandible), duration of biphosphonate treatment and to concomitant. Conclusion : The present cases series suggests that the described extraction protocol in IV biphosphonate patients allowed 100% bone healing and complete soft tissues healing in 81.8% of the extraction sites.The sites that have not fully recovered seemed to be related to different factors. [less ▲]

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Peer Reviewed
See detailPatient morbidity after 2 different surgical protocols to treat miller class I recession in the anterior maxilla: A Comparaitive Ramdomized Control Trial.
SALHI, Leila ULg; ROMPEN, Eric ULg; LECLOUX, Geoffrey ULg et al

Conference (2012, June)

Aim: The objective of this study was to compare two different periodontal plastic surgery procedures to treat Miller’s class I recession: a coronally advanced flap (control group) versus the pouch ... [more ▼]

Aim: The objective of this study was to compare two different periodontal plastic surgery procedures to treat Miller’s class I recession: a coronally advanced flap (control group) versus the pouch technique (test group), both of which were associated with connective tissue graft. Methods: Forty consecutive patients were included, with 20 patients being allocated for each group. The level of recession coverage, the keratinised tissue quantity, gingival aesthetics (PES), and postoperative outcomes were assessed for a follow-up period of 6 months. Results: After 6 months, both techniques allowed for the excellent mean root coverage of 96.3 ± 12.1% in the control group and of 91.3 ± 17.6% in the test group. Complete root coverage was achieved in 89.5% (17/19) and 79% (15/19) of the recession cases in the control and the test groups, respectively. A significant increase in keratinised tissue height (p=0.0011) was observed in the test group. A significant improvement in the pink aesthetic score was found in the 2 groups, but gingival texture displayed significantly better results in the test group (p<0.0001). No significant difference between the 2 groups was found in terms of the morbidity outcomes. Pain killer consumption was similar in the 2 groups and significantly decreased over time. [less ▲]

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Peer Reviewed
See detailDescription of the bone-remodeling pattern after socket preservation procedures in human: a methodological study
LAMBERT, France ULg; VINCENT, Kim ULg; VANHOUTTE, Vanessa ULg et al

Poster (2011)

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review ... [more ▼]

Background: The bone remodeling after tooth extraction can result in the loss of as much as 50% of the buccal wall and a global crestal reduction in width of 3.87mm according to a recent systematic review. Multiple surgical protocols using biomaterials are proposed in order to limit the typical postextraction bone resorption. However, because of the heterogeneity of the studies and, more specifically, of the assessment methods, it is difficult to assert the superiority of one technique over another. Aim: The objective of this study was to develop a new radiographic method to assess alveolar bone remodeling after socket preservation procedures. Methods: Sixteen extraction sites (in 14 patients) localized in the upper anterior maxilla were treated with bovine hydroxyapatite (0.25–1mm particles) and a saddled connective tissue graft. A radiographic 3-dimensional assessment of the hard tissues was performed at baseline and at 3 months after the procedure. Standardized horizontal measurements were taken at three corono apical levels ( 2, 5, and 9mm) and at three mesio-diatal level (Mesial, Center, and Distal) in the buccal and palatal aspects. Vertical measurements were also recorded in nine regions over the top of the alveolar crest. Results: Extraction socket-preservation technique assessed in the present study significantly reduced horizontal bone remodeling. The horizontal dimension of the crest decreased by 1.6mm (20%) in the cervical regions ( 2mm level), experienced a moderate decrease of 1mm (12%) at the 5mm level, and experienced a very low decrease of 0.5mm(6%) in the apical ( 8mm) level. The losses were always significantly higher in the buccal than in the palatal aspect. Buccally, the maximal bone remodeling at the cervical level remained below 1mm. Vertical bone resorption was homogeneous and was < 1mm in the nine measured regions. Conclusions and clinical implications: The radiographic measuring methodology proved to be accurate and reproducible. It can be applied in other clinical settings. Moreover, the surgical procedure evaluated in the present study, significantly limits the postextraction buccal bone remodeling compared with the data found in the literature for untreated extraction socket in the aesthetic area. However, a complete inhibition of the bone remodeling was not reached and the authors suggest a surgical technique using a ‘‘saddled’’ connective tissue graft to thicken buccal soft tissue biotype and consequently compensate for cervical bone loss. [less ▲]

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See detailBone regeneration using porous titanium particles vs. bovine hydroxyapatite: a sinus lift study in rabbits
LAMBERT, France ULg; LECLOUX, Geoffrey ULg; Léonard, Angélique ULg et al

Poster (2011)

Background: The use of porous titanium particles as space filling biomaterials for intraoral bone regeneration might be of interest because of both the mechanical stability and nonresorbable properties ... [more ▼]

Background: The use of porous titanium particles as space filling biomaterials for intraoral bone regeneration might be of interest because of both the mechanical stability and nonresorbable properties. Titanium particles were recently described for bone regeneration in sinus lifts and in the treatment of periimplantitis. Nevertheless, tissue integration and 3D bone regeneration with titanium particles were poorly explored in these previous reports. Aim: The first objective of this study was to qualitatively and quantitatively assess the bone formation process, particularly the long-term behavior and 3D volume stability of subsinusal bone regeneration, using titanium or bovine hydroxyapatite granules, in a rabbit model. The second objective was to evaluate the effect of the hydration of the BHA particles with a therapeutic concentration of doxycycline solution on the osteogenesis and biomaterial resorption. Methods: Rabbits underwent a double sinus lift procedure using one of three materials: grade 1 porous titanium particles (Ti), bovine hydroxyapatite (BHA) or chemically modified bovine hydroxyapatite (BHATTC). Animals were sacrificed after 1 week, 5 weeks or 6 months. Samples were analyzed using mCT and nondecalcified histology. Results: The materials used in each of the three groups allowed an optimal bone formation; bone quantities and densities were not statistically different between the three groups. At 6 months, more stable 3D volume stability was found with TI and BHATTC (P¼0.0033). At 5 weeks and 6 months, bone to material contact (BMC) corroborating osteoconduction was significantly higher with BHA and BHATTC than with Ti (P < 0.0001). Conclusions and clinical implications: Even though the studied biomaterials displayed different architectures, they are relevant candidates for sinus lift bone augmentation before dental implants because they allow adequate 3D stability and osteogenesis. However, to recommend the clinical use of Ti, both an observation on the drilling effects of Ti particles and clinical trials are needed. [less ▲]

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Peer Reviewed
See detailPhysico-chemical and morphological properties of current particulated biomaterials used in alveolar bone augmentations: a review.
LAMBERT, France ULg; Layrolle, Pierre; ROMPEN, Eric ULg et al

in Journal of Osteology and Biomaterials (2011), 2

The efficacy of grafting materials for alveolar bone regeneration procedures has been repeatedly corroborated by clinical and scientific evidence. Although an ever growing number of biomaterials are ... [more ▼]

The efficacy of grafting materials for alveolar bone regeneration procedures has been repeatedly corroborated by clinical and scientific evidence. Although an ever growing number of biomaterials are available on the market, the origins, material characteristics, bioactivity and osteoconductive properties of these products are not always known by clinicians, hence often hampering an adequate product selection. The purpose of this contribution was to provide an overview of five different types of osteoconductive grafting materials frequently used in dentistry (Bio-Oss®, Cerasorb M™, Bone Ceramic®, Natix®, Genos®) and to summarize their physico-chemical and morphological characteristics at the macro- and micro-scale. Furthermore, the influence of these properties on the in vivo behaviour of these biomaterials is discussed. The results of this study are presented as data sheets, which may prove helpful for clinicians in the design of their treatment strategies. [less ▲]

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See detailInfluence of space-filling materials in subantral bone augmentation: blood clot vs. autogenous bone chips vs. bovine hydroxyapatite
Lambert, France ULg; Léonard, Angélique ULg; Drion, Pierre ULg et al

in Clinical Oral Implants Research (2011), 22(5), 538-545

Aim: The first objective of the present study was to compare the short- and long-term 3D volume stability of sub-sinusal bone regeneration in rabbits using different space fillers. The second objective ... [more ▼]

Aim: The first objective of the present study was to compare the short- and long-term 3D volume stability of sub-sinusal bone regeneration in rabbits using different space fillers. The second objective was to assess qualitatively and quantitatively the early bone formation process and long-term behavior of the regenerated bone. Materials and methods: Fifteen rabbits underwent a double sinus lift procedure using: blood clot (Clot), autogenous bone chips (Auto) and bovine hydroxyapatite (BHA). Animals were euthanized at 1 week, 5 weeks and 6 months. Samples were subjected to X-ray microtomography and histology. Variations in the volume of bone augmentations were calculated at different time points. Qualitative analysis was performed using 7 μm sections and quantitative histomorphometric analyses were carried out using scanning electron microscopy. Results: From baseline (100%) to 5 weeks, the augmented volumes declined to 17.3% (Clot), 57.6% (Auto) and 90.6% (BHA). After 6 months, only 19.4% (Clot) and 31.4% (Auto) of initial volumes were found, while it remained more stable in the BHA group (84%). At 1 week, an initial osteogenesis process could be observed in the three groups along the bone walls. At 5 weeks, despite a significant decline in the volume, newly formed bone density was higher with Clot and Auto than with BHA. At 6 months, bone densities were statistically similar in the three groups. However, after 6 months, the surface invaded by newly formed bone (regenerated area) was significantly higher when BHA was used as space filler. In the BHA group, the biomaterial area slightly decreased from 42.7% (1 week) to 40% (5 weeks) and 34.9% (6 months) and the density of the composite regenerated tissue (bone+BHA) reached >50% at 6 months. Conclusions and clinical implications: The three space fillers allowed bone formation to occur. Nevertheless, augmented volumes declined in the Clot and Auto groups, while they remained stable with BHA. A slowly resorbable biomaterial might be suitable in sub-sinusal bone augmentation for preventing the re-expansion process and for augmenting the density of the regenerated tissues. [less ▲]

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See detailBiofilms bactériens et médecine dentaire
Simain-Sato, Franklin ULg; Rompen, Eric ULg; Heinen, Ernst ULg

in Revue Médicale de Liège (2010), 65 (10)

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Peer Reviewed
See detailRevisited rules of papilla level adjacent to single-tooth dental implants according recent implant designs. A retrospective study.
LECLOUX, Geoffrey ULg; Beaujan, Laurie; ROMPEN, Eric ULg et al

Poster (2010, October)

Background: According to Choquet and Tarnow principles (2001), a papilla is always present if the distance from the base of the contact point between two crowns to the crest of the bone is 5 mm or less ... [more ▼]

Background: According to Choquet and Tarnow principles (2001), a papilla is always present if the distance from the base of the contact point between two crowns to the crest of the bone is 5 mm or less. The arrival of new designs in implantology suggested more tissue preservation and so a possible evolution for the aesthetic treatments. Aim: This study was designed to determine whether the distance from the base of the contact point to the crest of the bone would correlate with the presence or absence of the interproximal papillae adjacent to single-tooth implants using the recent implant designs. Methods: A clinical, photographical and radiographical retrospective evaluation of the papilla level around single dental implants and their adjacent teeth was performed in the anterior maxilla in 34 patients restored with 39 implants. These implants were loaded at least 6 months and present a modified profile (Implants : NobelConcept and NobelActive, Nobel Biocare ; Bone Level, Straumann. Abutments : Platform-switching and curvy). Sixty-three papillae were available for evaluation. The Jemt index, the vertical distance between the base of the contact point and the bone crest, the distance from the papilla level to the contact point were measured. The measurements were rounded off to the nearest 0,001 millimeter and used with calibration computer programs (ImageJ) to be analyzed. The statistical analyses were realized with SAS program (SAS Institute, Cary, NC, USA). Results: When the measurements from the contact point to the crest of bone was 5 mm or less, the papilla was present 100% of the time. When the distance was 6 mm, the papilla was present 96% of the time. And when the distance was 7 and 8 mm, the papilla was present 57,14% and 50% of the time. Conclusions and clinical implications: These results show the influence of the bone crest on the presence or absence of papillae between implants and adjacent teeth. The data also show a positive influence for recent designs of implant and abutment systems. This designs shift the actual critical bone distance under the contact point from 5mm to 6mm and could improve the aesthetic outcome. [less ▲]

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See detailRoxolid a new implant material
LAMBERT, France ULg; ROMPEN, Eric ULg

Conference (2010, March 23)

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See detailRoxolid a new implant material
LAMBERT, France ULg; ROMPEN, Eric ULg

Conference (2010, February 23)

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See detailPrise en charge pluridisciplinaire d'une parodontite juvénile: Traitement Paro-Ortho-Prothétique
LAMBERT, France ULg; ROMPEN, Eric ULg

in Le point (2010), 218(Janvier -Février), 27-30

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Peer Reviewed
See detailOne-piece zirconia implants : 18 months clinical outcomes.
VANHOUTTE, Vanessa ULg; LAMBERT, France ULg; ROMPEN, Eric ULg

Conference (2009, December)

Purpose : The aim of the present study was to evaluate prospectively the clinical outcomes of a prototype one-piece zirconia implants after a -18 month follow-up. Material and methods : 20 prototype one ... [more ▼]

Purpose : The aim of the present study was to evaluate prospectively the clinical outcomes of a prototype one-piece zirconia implants after a -18 month follow-up. Material and methods : 20 prototype one-piece zirconia implants were placed and immediately restored with provisional protheses. A flapless or a minimally invasive approach was used for every implant placement. Bone levels were recorded at baseline and -1 year. Surgical, biological and prosthetic complications were also assessed. Results : The study included 15 patients. Most of the implants (90%) were placed at the anterior maxilla. Six of the implant sites were previously augmented with autogenous bone block grafts, 8 were managed with socket preservation techniques, 3 implants were immediatly placed after extraction and one implant was placed simultanously with a guided bone regeneration. Insertion torque (> 30N/cm2) was reached for all implants. The implant survival and success rates reached respectively 100% and 95%. One implant abutment fractured at placement because of an excessive insertion torque (> 50 N/cm2). No further complication occurred. Conclusion : From the preliminary results of this prospective clinical study, one-piece zirconia implants seem to success after 1 year despite they were often placed in critical clinical situtations (bone augmentations) and immediately restored. Further follow-up is needed to evaluate the long-term outcomes. [less ▲]

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