References of "Rollin, Frédéric"
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See detailBluetongue in northern Europe.
Thiry, Etienne ULg; Saegerman, Claude ULg; Guyot, Hugues ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2006), 159(10), 327

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See detailComparative responses to sodium selenite and Sel-Plex® organic selenium supplements in Belgian Blue cows and calves
Guyot, Hugues ULg; Rollin, Frédéric ULg; Andrieu, Sylvie et al

in Nutritional Biotechnology in the Feed and Food Industries (Alltech’s 22nd Annual Symposium) (2006)

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See detailTools to assess iodine deficiency in calves born from deficient and non deficient dams
Guyot, Hugues ULg; Uyttenhoef, Aude; Lebreton, Pascal et al

Poster (2006)

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See detailRelationship between haptoglobin, serum amyloid A, and clinical status in a survey of dairy herds during a 6-month period
Humblet, Marie-France ULg; Guyot, Hugues ULg; Boudry, Benjamin et al

in Veterinary Clinical Pathology (2006), 35(2), 188-193

Haptoglobin and serum amyloid A are major acute phase proteins in cattle. Dairy cattle often develop pathologic conditions in the peripartum period; acute phase proteins may be useful in their diagnosis ... [more ▼]

Haptoglobin and serum amyloid A are major acute phase proteins in cattle. Dairy cattle often develop pathologic conditions in the peripartum period; acute phase proteins may be useful in their diagnosis. Objectives: The purpose of this study was to compare the accuracy of serum haptoglobin (Hp) and serum amyloid A (SAA) concentrations with clinical health status for diagnosing disease during the peripartum period in dairy cattle. Methods: Dairy cows from 4 herds were evaluated every 15 days over a 6-month period. Health status was determined by thorough clinical examination. Haptoglobin and SAA concentrations were measured in serum using validated methods and the results were classifed as positive or negative based on defined cutoff points. Disease prevalence, sensitivity, and specificity were compared using clinical examination as the gold standard. Results: A total of 1896 samples from 158 cows were analyzed. Significant increases in mean Hp and SAA concentrations were observed in the week following parturition in both primiparous and multiparous cows, although high interindividual variability was observed. Both Hp and SAA had low sensitivity but higher specificity in determining disease status compared with clinical examination. Increased concentrations of Hp and SAAwere found in ,10% of samples from clinically healthy cows, except in the week after parturition. Conclusions: Haptoglobin and serum amyloid A should be used with caution as markers of inflammation in the week after calving. Poor sensitivity in other postpartum periods could be related to the higher incidence of chronic (vs acute) inflammation. Haptoglobin may be appropriate for routine screening, but further work needs to be done to assess its value as an indicator of herd health. [less ▲]

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See detailPatologie şi clinică medicală veterinară
Solcan, G.; Boghian, V.; Rollin, Frédéric ULg

Book published by Editura Ion Ionescu de la Brad (2005)

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See detailRespiratory Distress Syndrome in full-term newborn calves: clinical, laboratory and post-mortem findings
Rollin, Frédéric ULg; Danlois, Fabien; Aliaoui, Hamani et al

in Proceedings of the 23rd ACVIM (2005)

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See detailEmergence of bovine Ehrlichiosis in Belgium
Guyot, Hugues ULg; Vandeputte, Sébastien ULg; Sandersen, Charlotte ULg et al

Conference (2005)

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See detailClues for Differential Diagnosis of atypical myopathy
Votion, Dominique ULg; Amory, Hélène ULg; Sandersen, Charlotte ULg et al

in Proceeding of the Maastricht International Congress on Equine Medicine (MICEM) (2004, December)

Atypical myopathy (AM), also called “atypical myoglobinuria”, is a frequently and rapidly fatal myopathy of unknown origin occurring sporadically in grazing horses. As opposed to the exertional ... [more ▼]

Atypical myopathy (AM), also called “atypical myoglobinuria”, is a frequently and rapidly fatal myopathy of unknown origin occurring sporadically in grazing horses. As opposed to the exertional rhabdomyolysis syndrome (ERS), clinical signs of AM are not induced by exercise. The condition has been reported in several European countries including Belgium, France, Germany and Great Britain. Clinical signs of AM are characterised by muscular weakness, stiffness, recumbency, sweating and when urine is observed, myoglobinuria. These signs are characteristic but not pathognomonic of the disease; the differential diagnosis of sudden weakness, severe myopathy and/or unexpected death includes several neurogenic and myopathic disorders. The main pathologies that share clinical similarities with AM include the acute form of grass sickness (GS), acute piroplasmosis, botulism, ERS, the hyperkalemic periodic paresis (HPP), nutritional myopathy (NM; i.e. vitamin E and/or selenium deficiency), plants or drugs (i.e. ionophores intoxication) intoxication, tetanus and postanaesthesia myopathy. This report aims at reviewing key facts in history, clinical signs, clinical examination and laboratory findings that contribute towards the diagnosis of AM and/or invalidate the diagnosis of other pathologies. [less ▲]

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See detailCase report : A suspicion of cortico-cerebral necrosis in a Belgian Blue herd after ingestion of moulded silage
Guyot, Hugues ULg; Sandersen, Charlotte ULg; Aliaoui, Hamani et al

Poster (2004)

After ingestion of moulded beet pulp silage, cases of cortico-cerebral necrosis (CCN) and mortalities have been observed in a Belgian Blue (BB) herd. Contamination with Paecilomyces spp., a mould that ... [more ▼]

After ingestion of moulded beet pulp silage, cases of cortico-cerebral necrosis (CCN) and mortalities have been observed in a Belgian Blue (BB) herd. Contamination with Paecilomyces spp., a mould that produces byssochlamic acid, malformins and patulin, has been proven. Among these toxins, patulin is known to have cancerogenic, immunosuppressive and tremorgenic effects, but also acts on the respiratory and digestive systems. Twenty-five days after progressive introduction of beet pulp silage into the ration of a dual purpose BB herd, most of the animals showed diminished appetite, salivation and decreased milk production. All 35 cows were reluctant to consume the beet pulp silage, but continued to eat grass silage voluntarily. Seven of them showed anorexia and nervous symptoms, like head pressing and blindness. Four animals died within 1 week after onset of neurological symptoms. No necropsy has been performed, since legislation does not allow post-mortem examination of the central nervous system in the field. The three survivors had been treated successfully with thiamine (10 mg/kg, IV, TID) and recovered completely within five days. After the beet pulp silage had been identified as causative agent, it had been removed from the animals’ ration and no more clinical case has been observed. Four weeks later, the same beet pulp silage has been reintroduced into the animals’ ration and provoked again diminished appetite, salivation and a decrease in milk production in most of the animals. Clinical signs were also suggesting lead poisoning but any contact with lead containing material could have been excluded. Silage was obviously moulded and analysis revealed the presence of 1.6 million CFU Paecilomyces spp./g of silage. Although no further investigation has been made to identify the mycotoxins, an intoxication with patulin has been suspected, since other mycotoxins produced by these species are less toxic. Although it has not been described that CCN can be induced by ingestion of Paecilomyces spp., it seems that there is a close relation between ingestion of Paecilomyces-contaminated silage and observed clinical signs in this herd. [less ▲]

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See detailErgot poisoning in cattle
Brihoum, M.; Desmecht, Daniel ULg; Bony, S. et al

in Annales de Médecine Vétérinaire (2004), 148(2), 97-101

In addition to the financial losses that ergot ( Claviceps purpurea) contamination causes in crops, the ingestion of ergot-contaminated food by cattle results in an intoxication that develops in several ... [more ▼]

In addition to the financial losses that ergot ( Claviceps purpurea) contamination causes in crops, the ingestion of ergot-contaminated food by cattle results in an intoxication that develops in several patterns. The observed clinical troubles may involve different systems. In this paper, we reviewed the clinical signs observed in ergot-poisoned cattle and some diagnostic and prevention aspects. [less ▲]

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See detailBiochemical findings associated with atypical myopathy in grazing horses
Votion, Dominique ULg; Delguste, Catherine ULg; Amory, Hélène ULg et al

in Pflügers Archiv : European Journal of Physiology (2004), 447

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See detailAtypical Myopathy (Atypical Myoglobinuria)
Votion, Dominique ULg; Amory, Hélène ULg; Demoulin, Vincent ULg et al

in IVIS Reviews in Veterinary Medicine (2004)

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See detailStudy of the role and origin of endotoxemia in the pathogenesis of respiratory distress syndrome in the newborn calf.
Aliaoui, Hamani; Danlois, Fabien; Guyot, Hugues ULg et al

Poster (2004)

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See detailTrace elements deficiencies in the pathogenesis of respiratory distress syndrome in the mature newborn calf
Guyot, Hugues ULg; Aliaoui, Hamani; Rollin, Frédéric ULg

Poster (2004)

In Belgium, respiratory distress syndrome (RDS) is one of the leading causes of neonatal death in the mature hypermuscled Belgian Blue calf (BB) but also occurs in other cattle breeds. Major clinical ... [more ▼]

In Belgium, respiratory distress syndrome (RDS) is one of the leading causes of neonatal death in the mature hypermuscled Belgian Blue calf (BB) but also occurs in other cattle breeds. Major clinical signs (tachypnea, tachycardia and sometimes depression) develop in the first hours after birth and are due to insufficiency of functional surfactant. Knowing that trace elements deficiencies can slow pulmonary maturation, the aim of this study was to investigate trace elements status in 10 RDS affected BB herds in comparison with 6 reference herds without any evidence of RDS. In each herd, blood was sampled from 10 pregnant or freshly calved healthy cows. In each blood sample, the plasmatic zinc (Zn) and copper (Cu) contents and erythrocytic glutathion peroxydase activity (GSH-pxe) were measured and considered normal when above 15 μmol/L, 14 μmol/L and 250 IU/gHb, respectively. A herd was deficient in one element if at least 30 % of sampled animals were out of normal range for this element. Milk was also sampled and pooled from 10 other cows or, when possible, bulk milk was taken. Milk iodine (I) content was considered normal when above 80 μg/L. Results were compared between groups by Chi-square test. All RDS affected herds had low Zn and Cu concentrations and low GSH-pxe activity. Eight out of 10 had low I in milk. In the non-RDS affected herds, only 1 herd was deficient in I, Zn, Cu and had low GSH-pxe activity, 2 herds were deficient in Zn and Cu and 1 herd was deficient in Cu. RDS affected herds were significantly more often deficient in I and GSH-pxe than non-affected herds. It seems that the trace elements selenium (Se), Zn and Cu play an essential role in the development of RDS. The same applies for I, although not deficient in all herds. The reason for this might be that milk samples were taken during lactation, when cows’ nutrition was different and, in any case, supplemented in I. In mature babies, the same RDS is observed but its etiology is still unclear, although I deficiency in the mother is suspected to play a major role in pathogenesis. Furthermore, it has been demonstrated that a Se-dependent deiodinase is responsible for transformation of thyroxine (T4) into tri-iodothyronine (T3), which is essential for effective surfactant production. In conclusion, results suggest an association between RDS in mature newborn calves and trace elements deficiencies, especially Se and I, that can be responsible for primary surfactant insufficiency. [less ▲]

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See detailLa myopathie atypique des équidés: particularités cliniques, examens complémentaires et hypothèses étiologiques.
Votion, Dominique ULg; Delguste, Catherine ULg; Amory, Hélène ULg et al

in Journée AVEF (Association des Vétérinaires Equins Français) (2003, October)

La myopathie atypique (MA) des équidés, encore appelée myoglobinurie atypique des chevaux au pré, est un syndrome caractérisé par l’apparition soudaine de faiblesse musculaire, de raideur, de tremblements ... [more ▼]

La myopathie atypique (MA) des équidés, encore appelée myoglobinurie atypique des chevaux au pré, est un syndrome caractérisé par l’apparition soudaine de faiblesse musculaire, de raideur, de tremblements et de sudation profuse généralisée ou localisée. L’animal adopte rapidement une position en décubitus sternal ou latéral. Lorsque de l’urine est émise, celle-ci a une couleur brune « chocolatée ». L’examen clinique révèle fréquemment de la tachycardie, de l’hypothermie et de la dyspnée. Le dosage de l’activité sérique de la créatinine kinase contribue à la présomption de MA en démontrant une destruction musculaire massive mais le diagnostic définitif repose nécessairement sur l’examen histologique des muscles intervenant dans la posture et la respiration, muscles généralement atteints lors de cette maladie ainsi que sur l’examen du muscle cardiaque où des lésions de dégénérescence sont occasionnellement observées. Diverses hypothèses étiologiques sont en cours d’investigation et les plus probables incriminent l’action d’une mycotoxine ou d’une toxine d’origine bactérienne, ingérée ou produite dans le tractus digestif. Néanmoins, une carence nutritionnelle n’est pas exclue. Quelle que soit la cause, il semble que des conditions climatiques défavorables favorisent le déclenchement des symptômes. La récolte de données épidémiologiques permettra de mieux définir les moyens de prévention de cette maladie souvent fatale. [less ▲]

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See detailDifferential diagnosis of neurologically expressed disorders in Western European cattle
Saegerman, Claude ULg; Claes, L.; Dewaele, Albert et al

in Revue Scientifique et Technique (International Office of Epizootics) (2003), 22(1), 83-102

A classification of neurological or neurologically expressed disorders that occur in Western European cattle aged 12 month and over has been established on the basis of aetiology, frequency and conditions ... [more ▼]

A classification of neurological or neurologically expressed disorders that occur in Western European cattle aged 12 month and over has been established on the basis of aetiology, frequency and conditions of appearance, age and type of animals concerned and the main clinical signs observed. Neurologically expressed disorders have been classified according to different groups of causes: biological, non-biological and non-specific or unknown. Differential diagnosis of neurologically expressed disorders is an essential element in the clinical epidemiological surveillance of bovine spongiform encephalopathy. A growing number of aetiologies are described in the scientific literature. The identification and centralised management of neurological disorders will make it possible, one the one hand, to take account of the inherent variability in the clinical forms encountered and in the diagnostic approaches of the observers and, on the other hand, to identify new risk factors in order to control them. [less ▲]

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See detailEpisode de dyspnée consécutive à une intoxication par l’ergot dans une exploitation laitière
Brihoum, Mounir ULg; Desmecht, Daniel ULg; Bony, S. et al

in Annales de Médecine Vétérinaire (2003), 147(5), 353-358

A chronic consumption (3.5 months) of ergot (Claviceps purpurea) contaminated triticale in dairy cows resulted in dyspnea, mainly expiratory, consistent with interstitial pneumonia and emphysema. These ... [more ▼]

A chronic consumption (3.5 months) of ergot (Claviceps purpurea) contaminated triticale in dairy cows resulted in dyspnea, mainly expiratory, consistent with interstitial pneumonia and emphysema. These troubles can be compared to many observations done in humans after long lasting treatments with ergot derivatives [less ▲]

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See detailDiagnostic différentiel des troubles à expression nerveuse dans l’espèce bovine en Europe occidentale
Saegerman, Claude ULg; Claes, L.; Dewaele, A. et al

in Revue Scientifique et Technique (International Office of Epizootics) (2003), 22(1), 61-82

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