References of "Rollin, Frédéric"
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See detailFluidothérapie parentérale pratique chez les bovins
Rollin, Frédéric ULg

in Annales de Médecine Vétérinaire (1997), 141(2), 89-111

After setting up the main indications for parenteral fluid therapy in calves and adult cattle, the means are studied to practically evaluate on the field the dehydration, acid-base status, electrolyte ... [more ▼]

After setting up the main indications for parenteral fluid therapy in calves and adult cattle, the means are studied to practically evaluate on the field the dehydration, acid-base status, electrolyte disturbances and glycemia. The various classes of fluids are then considered as a function of the indications. Use of transfusion, hypertonic solutions and parenteral nutrition is broached. Routes and techniques of fluid administration are detailed. Obstacles encountered by the bovine practitioner when using parenteral fluid therapy are emphasized just as the means to overcome them. In this regard, it is described how to correctly prepare fluids for suited parenteral use in cattle. In fact, the present laws do not given this allowance to the practitioners. However, in most cases, it constitutes the only economical option avoiding worthless sufferings and death of the animal. [less ▲]

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See detailMultiple-Breath Washout and Washin Experiments in Steers
Rollin, Frédéric ULg; Desmecht, Daniel ULg; Verbanck, S. et al

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1996), 81(2), 957-63

Multiple-breath N2 washouts (WO) and washins (WI) were performed during regular tidal breathing in 11 unsedated healthy steers approaching pulmonary functional maturity (mean body weight = 271 kg). They ... [more ▼]

Multiple-breath N2 washouts (WO) and washins (WI) were performed during regular tidal breathing in 11 unsedated healthy steers approaching pulmonary functional maturity (mean body weight = 271 kg). They inspired 20% O2 in 80% Ar during the WO and air during the WI. For each steer, we computed two indexes of ventilation inhomogeneity from the N2 WO curves: 1) the curvilinearity of the logarithm of end-tidal N2 concentrations as a function of cumulative expired volume reflected in the ratio of two slopes fitted between 100 and 50% and between 50 and 10%, respectively, of end-tidal N2 concentration of the first breath of the WO; and 2) the N2 phase III slope divided by the mean expired concentration (Sn) of each breath also plotted as a function of cumulative expired volume. Equivalent computation of both parameters was done on WI and WO curves, and similar results were obtained. The mean slope ratio was 0.812 +/- 0.119 (SD) for all the steers, which is consistent with topographic gravity-dependent specific ventilation distribution inhomogeneity. Sn was independent of the breath number both for WO and WI (mean Sn = 0.130 +/- 0.057 liters-1), suggesting that emptying between unequally ventilated units, is synchronous. This behavior resembles that observed in rats postmortem (S. Verbanck, E.R. Weibel, and M. Paiva. J. Appl Physiol. 71: 847-854, 1991) but contrasts with experiments in humans, in whom convection-dependent ventilation inhomogeneities generate a marked increase in Sn throughout the entire WO (A. B. H. Crawford, M. Makowska, M. Paiva, and L. A. Engel. J. Appl. Physiol. 59: 838-846, 1985). This is surprising because one would expect gravity-dependent sequential emptying in animals of this size. [less ▲]

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See detailControl of breathing in healthy and pasteurella-exposed calves after 5-HT receptor blockade
Rollin, Frédéric ULg; Close, R; Linden, Annick ULg et al

in Proceedings of the XIXth World Association for Buiatrics Congress (1996)

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See detailComparison of Cardiac Function in Double-Muscled Calves and in Calves with Conventional Muscular Conformation
Amory, Hélène ULg; Desmecht, Daniel ULg; Linden, Annick ULg et al

in American Journal of Veterinary Research (1994), 55(4), 561-6

During growth, central venous, right ventricular, pulmonary arterial, pulmonary capillary wedge, and systemic arterial pressures, heart rate, and cardiac output were repeatedly measured in 41 Friesian ... [more ▼]

During growth, central venous, right ventricular, pulmonary arterial, pulmonary capillary wedge, and systemic arterial pressures, heart rate, and cardiac output were repeatedly measured in 41 Friesian calves, considered as having conventional muscular conformation, and in 19 Belgian White and Blue double-muscled calves. A total of 123 and 70 recordings were collected in conventional and double-muscled calves, respectively. These circulatory indices were calculated: stroke volume, cardiac and stroke indices, pulmonary and systemic pulse pressures, pulmonary and systemic vascular resistance indices, and right and left ventricular work indices. Results indicated that systemic arterial and pulse pressures, as well as cardiac output, stroke volume, cardiac and stroke indices, and right and left ventricular work indices were significantly (P < or = 0.05 to 0.001) lower but, in contrast, pulmonary and systemic vascular resistance indices were significantly (P < or = 0.001) higher in double-muscled than in conventional calves. Right-sided vascular pressures and heart rate were similar in the 2 groups. These results indicated that global cardiac performance may be considerably poorer in double-muscled calves. Diminished cardiac performance of double-muscled calves appears to be related neither to relative bradycardia nor to reduced ventricular preload. The potential role of increased ventricular afterload or of reduced myocardial contractility in double-muscled cattle should be determined by direct measurements. [less ▲]

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See detailControl of breathing in unanesthetized healthy and Pasteurella-exposed calves after 5-HT2 receptor antagonism by metrenperone
Rollin, Frédéric ULg; Close, A; Linden, Annick ULg et al

in Proceedings of the XVIIIth World Buiatrics Congress (1994)

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See detailReduced cardiac functional capacity as a consequence of the double-muscled conformation selection in the Belgian White and Blue breed
Amory, Hélène ULg; Desmecht, Daniel ULg; Linden, Annick ULg et al

in Proceedings of the XVIIIth World Buiatrics Congress, Bologna, Italy (1994)

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See detailEctopie cervicale du coeur chez un veau
Gabriel, Annick ULg; Vandeputte, Sébastien ULg; Rollin, Frédéric ULg et al

in Annales de Médecine Vétérinaire (1994), 138

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See detail5-HT challenge in healthy vigile calves after MDL72222 pretreatment
Linden, Annick ULg; Desmecht, Daniel ULg; Rollin, Frédéric ULg et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailControl of breathing in healthy and Pasteurella exposed calves after 5-HT2 receptor blockade
Rollin, Frédéric ULg; Close, Patricia ULg; Linden, Annick ULg et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailAirway occlusion pressure and diaphragm global electromyograph analysis for evaluation of inspiratory muscle drive and neuromechanical coupling in cattle
Desmecht, Daniel ULg; Linden, Annick ULg; Rollin, Frédéric ULg et al

in American Journal of Veterinary Research (1994), 55

Although healthy and diseased bovine respiratory tracts have been intensively studied during the last years, to the authors' knowledge, there have been no attempts to objectively examine the inspiratory ... [more ▼]

Although healthy and diseased bovine respiratory tracts have been intensively studied during the last years, to the authors' knowledge, there have been no attempts to objectively examine the inspiratory drive from the brain to the nerves and muscles and its transformation in pressure. Such technique would be useful in assessing the possibility of altered ventilatory drive or inspiratory muscle fatigue in the context of an animal with ventilatory failure. The relation among ventilation, airway opening occlusion pressure generated 100 milliseconds after onset of inspiration (Pawo100ms) and 6 indexes describing diaphragmatic electromyographic activity (EMGdi) recorded via implanted fishhooks was evaluated during free and impeded CO2 rebreathing in 6 young bulls. The best significant linear correlations (r > 0.8) with inspiratory center afferent stimulation, as judged by end-tidal CO2 concentration in expired air, were found for Pawo100ms, peak moving time average or variance EMGdi, and mean integrated EMGdi, whatever had been the respiratory impedance. However, with an inspiratory load, Pawo100ms responses systematically had greater increase for a given change in the driving EMGdi, implying dependence of the former not only on neural input, but also on configurational factors that determine inspiratory muscle excitation-pressure generation couplings. The reproducibility of EMGdi absolute values and changes was satisfactory up to 10 hours, but could not be repeated from one day to the other. It was concluded that, provided the constancy of the electrical coupling of the recording system to the tissue being studied is ensured, specific EMGdi and Pawo100ms values correlate reliably with amount of CO2 during free and loaded breathing.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailOxygen Transport Chain in Double-Muscled Blue Belgian Cattle
Lekeux, Pierre ULg; Amory, Hélène ULg; Desmecht, Daniel ULg et al

in British Veterinary Journal (The) (1994), 150(5, Sep-Oct), 463-471

The physiological peculiarities of the oxygen transport chain in double-muscled Blue Belgian cattle are described. The investigations performed at several levels of the oxygen transport chain suggest that ... [more ▼]

The physiological peculiarities of the oxygen transport chain in double-muscled Blue Belgian cattle are described. The investigations performed at several levels of the oxygen transport chain suggest that the increased susceptibility of these cattle to stress, resulting mainly in respiratory diseases, is due to an insufficient functional reserve capacity mainly involving the pulmonary and cardiovascular systems. The resulting lack of 'functional hardiness' of the oxygen transport chain is seen in those double-muscled cattle which do not react in an appropriate or predictable way when submitted to a hostile environment. [less ▲]

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See detailGrowth-induced haemodynamic changes in healthy Friesian calves
Amory, Hélène ULg; Desmecht, Daniel ULg; Linden, Annick ULg et al

in Veterinary Record : Journal of the British Veterinary Association (1993), 132(17), 426-434

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See detailEconomic, Clinical and Functional Consequences of a Treatment Using Metrenperone During an Outbreak of Shipping Fever in Cattle
Genicot, Bruno; Mouligneau, Frédéric; Rollin, Frédéric ULg et al

in Veterinary Record : Journal of the British Veterinary Association (1993), 132(10), 245-247

Eighteen of 91 seven- to nine-month-old Belgian white and blue double-muscled male fattening cattle developed typical signs of shipping fever. They were all injected intramuscularly once a day for three ... [more ▼]

Eighteen of 91 seven- to nine-month-old Belgian white and blue double-muscled male fattening cattle developed typical signs of shipping fever. They were all injected intramuscularly once a day for three days with 5 mg/kg of enrofloxacin, and in addition nine selected at random were injected intramuscularly five times at 12 hour intervals with 0.1 mg/kg of metrenperone, a 5-hydroxytryptamine blocker, the other nine receiving a placebo. During the outbreak of shipping fever metrenperone showed effective antipyretic properties, and all the calves treated with it made a complete recovery. Moreover, during the 360 day fattening period following the outbreak, the cattle treated with metrenperone gained on average 45.4 kg more weight than the control cattle. [less ▲]

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See detailPulmonary Response to Intravenous Administration of 5-Hydroxytryptamine after Type-2 Receptor Blockade in Healthy Calves
Linden, Annick ULg; Desmecht, Daniel ULg; Amory, Hélène ULg et al

in American Journal of Veterinary Research (1993), 54(1), 168-73

The purpose of this study was to investigate the mechanism by which 5-hydroxytryptamine (5-HT) modifies respiratory function, specifically, hyperventilation, diffuse bronchoconstriction, and pulmonary ... [more ▼]

The purpose of this study was to investigate the mechanism by which 5-hydroxytryptamine (5-HT) modifies respiratory function, specifically, hyperventilation, diffuse bronchoconstriction, and pulmonary arterial hypertension in cattle. We determined whether the IV response to 5-HT in calves was attributable to stimulation of 5-HT2 receptors. Six healthy unsedated young bull calves of the Friesian (n = 4) and of the Belgian White and Blue (n = 2) breeds were used. A specific 5-HT2 antagonist (metrenperone, 0.05 mg/kg of body weight) was administered IM 30 minutes before the cattle were given a 5-minute IV 5-HT infusion. Pulmonary function values were registered before, during, and after the 5-HT challenge infusion. Minute volume increased significantly, because of an increase in respiratory rate. Conversely, lung dynamic compliance, total pulmonary resistance, and pulmonary arterial pressure were not changed. We concluded that in cattle, 5-HT-induced ventilatory response is not mediated through activation of 5-HT2 receptors. However, the 5-HT2 receptors are involved in 5-HT-induced broncho- and pulmonary vasoconstriction. [less ▲]

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See detailNormal Electro- and Vectorcardiographic Data in the Growing Friesian Calf Using a Semi-Orthogonal Lead System
Amory, Hélène ULg; Genicot, B; Rollin, Frédéric ULg et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1993), 40(2), 81-92

This study derives normal values for electro- and vectorcardiographic parameters, as generated by the Holmes semi-orthogonal lead system, in healthy growing calves. Sixty-four electrocardiograms were ... [more ▼]

This study derives normal values for electro- and vectorcardiographic parameters, as generated by the Holmes semi-orthogonal lead system, in healthy growing calves. Sixty-four electrocardiograms were recorded from healthy Friesian calves aged from one week to one year. Waveform and duration were analysed and compared in the X-, Y- and Z-leads. The modal P, QRS and T tridimensional vectors were graphically constructed and their magnitude and orientation were calculated. The duration of waves and intervals were similar to data previously reported in the bovine species. Differences from data reported in other species were attributed to heart rate. The duration of waves and QT and ST intervals significantly lengthened with the decrease in heart rate which occurred during growth. PR interval significantly lengthened with physical maturation, and this change was independent of the decrease in heart rate. The magnitude and the orientation of the spatial modal vectors were approximately similar to the few data previously reported in cattle and in other ungulates and were not affected by somatic growth [less ▲]

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See detailComparative study of the body surface electrocardiogram in double-muscled and conventional calves.
Amory, Hélène ULg; Rollin, Frédéric ULg; Genicot, Bruno et al

in Canadian Journal of Veterinary Research = Revue Canadienne de Recherche Vétérinaire (1993), 57(3), 139-45

The purpose of this work was to study electrocardiographic features of double-muscled beef cattle. Electrocardiograms were recorded on one to six occasions from each of a group of 18 conventional calves ... [more ▼]

The purpose of this work was to study electrocardiographic features of double-muscled beef cattle. Electrocardiograms were recorded on one to six occasions from each of a group of 18 conventional calves of the Friesian breed and 29 double-muscled calves of the Belgian White and Blue breed. Ages of the calves at the times of examination ranged from eight to 348 days. The Holmes semi-orthogonal lead system was used. The waves and interval durations and the tridimensional P, QRS, and T modal vector orientation and amplitude were calculated. The magnitude of the cardiac vectors was significantly lower and the ventricular waves and QT interval duration significantly shorter in the double-muscled than in the conventional calves. The P modal vector pointed significantly less downwards and the QRS modal vector pointed significantly more forwards and less up- and rightwards in the Belgian White and Blue, than in the Friesian group. Most of the observed differences might be a consequence of the bodily, and more specifically the thoracic, conformation of the former calves. However, the lower cardiac vector magnitude and shorter wave and interval durations might also reflect lower cardiac mass in the double-muscled subjects. [less ▲]

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See detailControl of breathing in resting and exercising animals
Lekeux, Pierre ULg; Rollin, Frédéric ULg; Art, Tatiana ULg

in Lekeux, Pierre (Ed.) Pulmonary Function in Healthy, Exercising and Diseased Animals (1993)

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See detailComparison of three metrenperone dosage regimens inhibiting the 5-hydroxytryptamine-induced pulmonary dysfunction in cattle
Linden, Annick ULg; Desmecht, Daniel ULg; Amory, Hélène ULg et al

in Research in Veterinary Science (1993), 55

The effects of a 5-hydroxytryptamine (5-HT) challenge infusion on pulmonary function values were studied in healthy calves, pretreated with varying doses of metrenperone, a selective type 2 serotonergic ... [more ▼]

The effects of a 5-hydroxytryptamine (5-HT) challenge infusion on pulmonary function values were studied in healthy calves, pretreated with varying doses of metrenperone, a selective type 2 serotonergic (5-HT2) antagonist. In the first part of the experiment, the 5-HT challenge was performed 30 minutes after administration of metrenperone at a dose of 0.025 mg kg-1 (group 1, n = 8), 0.050 mg kg-1 (group 2, n = 8) and 0.100 mg kg-1 (group 3, n = 7). In the second part, the 5-HT challenge was performed 12 hours after administration of metrenperone at a dose of 0.050 mg kg-1 (group 4, n = 5) and 0.100 mg kg-1 (group 5, n = 5). None of the three doses of metrenperone influenced the 5-HT-induced ventilatory changes. For the challenge performed 30 minutes after blockade, all three doses inhibited the bronchoconstrictive process triggered by the 5-HT challenge. There was no dose-related inhibition. On the other hand, when the challenge was performed 12 hours after metrenperone, there was a dose-related inhibition with only the higher dose (0.100 mg kg-1) showing a significant efficacy in inhibiting 5-HT-induced bronchoconstriction. It is concluded that, if 5-HT is involved in the pathophysiological processes of respiratory diseases in cattle, a 5-HT2 blockade with metrenperone at a dose rate of 0.100 mg kg-1 and with a dosage interval of 12 hours should improve pulmonary function. [less ▲]

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See detailTransdiaphragmatic Pressure Measurement in Cattle: Technical Data
Desmecht, Daniel ULg; Rollin, Frédéric ULg; Lekeux, Pierre ULg

in Research in Veterinary Science (1992), 53(2), 148-53

Techniques and methods required for accurate and reproducible measurements of transdiaphragmatic pressure (Pdi), were studied in seven-week and five-month-old calves. Since reliable pleural pressure ... [more ▼]

Techniques and methods required for accurate and reproducible measurements of transdiaphragmatic pressure (Pdi), were studied in seven-week and five-month-old calves. Since reliable pleural pressure measurement in cattle has already been described, separate experiments were conducted to compare retrodiaphragmatic pressures measured (i) with balloon-catheters and needle catheters, (ii) before and after eructation and (iii) in the ruminal and in the peritoneal cavities. Whereas respiratory-induced pressure changes were equally transmitted throughout the rumen content, a marked anteroposterior damping was observed as the recording site in the abdominal cavity was moved away from the diaphragm (P < 0.0001). It was concluded that the most appropriate and accurate way to measure Pdi changes in polygastric animals is to measure the pressure changes existing in the mid-thoracic portion of the oesophagus and in the liquid content of the rumen with balloon-tubing units. Neither growth- and diet-related rumen enlargement nor eructation, which are two typical characteristics of ruminants, altered the reliability of retrodiaphragmatic pressure measurements in the two age groups studied. [less ▲]

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