References of "Rieger, Jutta"
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See detailNew prospects for the grafting of functional groups onto aliphatic polyesters. Ring-opening polymerization of alpha- or gamma-substituted epsilon-caprolactone followed by chemical derivatization of the substituents
Lecomte, Philippe ULg; Riva, Raphaël ULg; Schmeits, Stephanie ULg et al

in Macromolecular Symposia (2006), 240

Recent progress in the synthesis of aliphatic polyesters, substituted by pendent functional groups, has been reviewed. Two main strategies have to be distinguished. The first route consists of the ring ... [more ▼]

Recent progress in the synthesis of aliphatic polyesters, substituted by pendent functional groups, has been reviewed. Two main strategies have to be distinguished. The first route consists of the ring-opening polymerization of F,caprolactone substituted by various functional groups, protected if needed, in alpha- or gamma-position. In a second strategy, the functional groups are grafted onto preformed polyesters chains in alpha-position of the carbonyl groups. alpha-chloro-epsilon-caprolactone is quite an interesting monomer because, after polymerization, the activated chloride can be easily derivatized by atom transfer radical addition and "click" chemistry, respectively. Similarly, gamma-acrylic-epsilon-caprolactone is precursor of (co)polyesters wellsuited to derivatization of the pendent double bonds by Michael addition. [less ▲]

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See detailDesign of stealth nanoparticles for drug delivery based on new amphiphilic copolymers
Rieger, Jutta ULg; Passirani, Catherine; Dubois, Philippe et al

Conference (2006, May 18)

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See detailControlled synthesis of an ABC miktoarm star-shaped copolymer by sequential ring-opening polymerization of ethylene oxide, benzyl beta-malolactonate, and epsilon-caprolactone
Rieger, Jutta ULg; Coulembier, Olivier; Dubois, Philippe ULg et al

in Macromolecules (2005), 38(26), 10650-10657

This paper reports on the synthesis of an amphiphilic miktoarm ABC star-shaped copolymer, s[(PEO)(PMLABz)(PCL)], consisting of biocompatible/bioresorbable arms. Indeed, PEO is a hydrophilic biocompatible ... [more ▼]

This paper reports on the synthesis of an amphiphilic miktoarm ABC star-shaped copolymer, s[(PEO)(PMLABz)(PCL)], consisting of biocompatible/bioresorbable arms. Indeed, PEO is a hydrophilic biocompatible poly(ethylene oxide) arm, PMLABz is a poly(benzyl beta-malolactonate) arm precursor of a pH-sensitive bioresorbable poly(beta-malic acid) block, and PCL is a hydrophobic bioresorbable poly(epsilon-caprolactone) arm. Each constitutive arm was prepared by ring-opening polymerization. A double-headed PEO macroinitiator [PEO-(OH)-COO-K+] was first prepared by selective hydrolysis of the alpha-lactone (2-oxepanone) end group of PEO chains end-capped by a omega-methoxy group. The anionic polymerization of benzyl beta-malolactonate (MLABz) was selectively initiated by the alpha-potassium carboxylate end group of PEO in the presence of 18-crown-6 ether. The polymerization of epsilon-caprolactone (epsilon-CL) was initiated by the hydroxyl group left at the junction of the two blocks of the as-prepared PEO-b-PMLABz diblock copolymer, in the presence of tin(II) bis(2-ethylhexanoate) (Sn(Oct)(2)). The macroinitiator, the intermediate diblock, and the final miktoarm. star-shaped copolymer were analyzed by H-1 NMR spectroscopy and size exclusion chromatography. [less ▲]

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See detailFunctionlization of biodegradable aliphatic polyesters by mannose-residue for the design of surface-modified polymeric nanoparticles
Rieger, Jutta ULg; Stoffelbach, François; Stoilova, Olya et al

Conference (2005, June 01)

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See detailSynthesis of novel functional PEO as builiding block for biomaterials
Rieger, Jutta ULg; Bernaerts, K.; Qiiu, Hongjin et al

Poster (2005, June 01)

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See detailVersatile functionalization and grafting of poly(epsilon-caprolactone) by Michael-type addition
Rieger, Jutta ULg; Van Butsele, Kathy ULg; Lecomte, Philippe ULg et al

in Chemical Communications (2005), (2), 274-276

The Michael-type addition of aliphatic (co)polyesters onto gamma-acryloyloxy epsilon-caprolactone units is a very straightforward technique of functionalization and grafting, which is tolerant to a ... [more ▼]

The Michael-type addition of aliphatic (co)polyesters onto gamma-acryloyloxy epsilon-caprolactone units is a very straightforward technique of functionalization and grafting, which is tolerant to a variety of functional groups and does not require intermediate protection/deprotection steps. [less ▲]

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See detailLactone end-capped poly(ethylene oxide) as a new building block for biomaterials
Rieger, Jutta ULg; Bernaerts, Katrien V.; Du Prez, Filip E et al

in Macromolecules (2004), 37(26), 9738-9745

This paper reports on the synthesis of a novel poly(ethylene oxide) (PEO) macromonomer, which can be copolymerized with epsilon-caprolactone (epsilon-CL) by ring-opening polymerization (ROP). PEO chains ... [more ▼]

This paper reports on the synthesis of a novel poly(ethylene oxide) (PEO) macromonomer, which can be copolymerized with epsilon-caprolactone (epsilon-CL) by ring-opening polymerization (ROP). PEO chains end-capped by an epsilon-caprolactone unit (gammaPEO(.)CL) have been synthesized by living anionic ring-opening polymerization of ethylene oxide (EO) initiated by the potassium alkoxide of 1,4-dioxaspiro[4.5]decan-8-ol, followed by derivatization of the acetal into a ketone and the Baeyer-Villiger oxidation of the ketone into a lactone. The end-capping of PEO by epsilon-CL was assessed by FTIR, MALDI-TOF, and H-1 NMR spectroscopy. This type of macromonomer is a precursor of amphiphilic comblike copolymers consisting of a biodegradable hydrophobic backbone of poly-(epsilon-caprolactone) (PCL) and hydrophilic PEO grafts. Copolymerization of gammaPEO(.)CL with epsilon-CL was successfully initiated by aluminum alkoxide. [less ▲]

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See detailPLA-coated gold nanoparticles for the labeling of PLA biocarriers
Qiu, Hongjin; Rieger, Jutta ULg; Gilbert, Bernard ULg et al

in Chemistry of Materials (2004), 16(5), 850-856

POly-DL-lactide end-capped by a protected thiol was synthesized by bulk ring-opening polymerization (ROP) of DL-lactide initiated by the reaction product of aluminum isopropoxide [Al (iOPr) (3)] with ... [more ▼]

POly-DL-lactide end-capped by a protected thiol was synthesized by bulk ring-opening polymerization (ROP) of DL-lactide initiated by the reaction product of aluminum isopropoxide [Al (iOPr) (3)] with alpha- (2,4-dinitrophenylsulfenyl) ethanol. After the thiol deprotection, PLA-SH was used to stabilize gold nanoparticles. Either these nanoparticles were prepared in the presence of PLA-SH, or PLA-SH was substituted for part of the undecanethiol (C11SH) that stabilized preformed gold nanoparticles. In contrast to C11SH-coated nanoparticles, those stabilized by PLA-SH were successfully entrapped into 100-nm PLA nanocarriers prepared by nanoprecipitation. This is an easy technique to label PLA biocarriers and therefore trace their fate in vivo. [less ▲]

Detailed reference viewed: 63 (2 ULg)
See detailDesign of nanoobjects endowed with specific properties
Willet, Nicolas ULg; Qiu, Hongjin; Rieger, Jutta ULg et al

Conference (2004, March)

Detailed reference viewed: 8 (4 ULg)
See detailPreparation and labelling of biodegradable drug nanocarriers
Rieger, Jutta ULg; Qiu, Hongjin; Mazza, Michaël et al

Poster (2003, May 16)

Detailed reference viewed: 19 (5 ULg)