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See detailReport of the 3rd Havemeyer workshop on allergic diseases of the Horse, Holar, Iceland, June 2007
Marti, E.; Gerber, V.; Wilson, A. D. et al

in Veterinary Immunology and Immunopathology (2008), 126(3-4), 351-361

Allergic diseases occur in most mammals, although some species such as humans, dogs and horses seem to be more prone to develop allergies than others. In horses, insect bite hypersensitivity (IBH), an ... [more ▼]

Allergic diseases occur in most mammals, although some species such as humans, dogs and horses seem to be more prone to develop allergies than others. In horses, insect bite hypersensitivity (IBH), an allergic dermatitis caused by bites of midges, and recurrent airway obstruction (RAO), a hyperreactivity to stable born dust and allergens, are the two most prevalent allergic diseases. Allergic diseases involve the interaction of three major factors: (i) genetic constitution, (ii) exposure to allergens, and (iii) a dysregulation of the immune response determined by (i) and (ii). However, other environmental factors such as infectious diseases, contact with endotoxin and degree of infestation with endoparasites have been shown to influence the prevalence of allergic diseases in humans. How these factors may impact upon allergic disease in the horse is unknown at this time. The 3rd workshop on Allergic Diseases of the Horse, with major sponsorship from the Havemeyer Foundation, was held in Holar, Iceland, in June 2007 and focussed on immunological and genetic aspects of IBH and RAO. This particular venue was chosen because of the prevalence of IBH in exported Icelandic horses. The incidence of IBH is significantly different between Icelandic horses born in Europe or North America and those born in Iceland and exported as adults. Although the genetic factors and allergens are the same, exported adult horses show a greater incidence of IBH. This suggests that environmental or epigenetic factors may contribute to this response. This report summarizes the present state of knowledge and summarizes important issues discussed at the workshop. [less ▲]

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See detailBilan medico-sportif du yearling a l’entrainement
Toussaint; Fraipont, Audrey ULg; Wagemans, Marie-Christine et al

in 35èmes Journées AVEF (2007)

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See detailPotential use of micro-array technology (bio-puce) in the diagnosis of inflammatory disorders in the horse
Lekeux, Pierre ULg; Thomas, A.; Ramery, Eve ULg et al

in XVII. Tagung über Pferdekrankheiten im Rahmen der EQUITANA (2007)

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See detailEvaluation de l’efficacité du Caprofène lors de bronchoneumonie expérimentale bovine à Mannheimia haemolytica
Wallemacq, Hugues; Boutet, Philippe; Zecchinon, L. et al

in Revue de Médecine Vétérinaire (2007), 158(8-9), 418-424

M. haemolytica serotype A1 (formerly known as Pasteurella) is the most important and commonly isolated bacterial pathogen from fatal cases of bovine fibrinous pleuroneumonia. M. haemolytica and its two ... [more ▼]

M. haemolytica serotype A1 (formerly known as Pasteurella) is the most important and commonly isolated bacterial pathogen from fatal cases of bovine fibrinous pleuroneumonia. M. haemolytica and its two principal toxins, the lipopolysaccharides (LPS) and the leukotoxin (LktA) induce the recruitment, the activation and the necrosis of neutrophils involved in the pathogenicity of bovine pneumonic mannheimiosis (BPM). The objective of this study was to determine whether systemic therapy with carprofène (Rimadyl®*), a non-steroidal anti-inflammatory drug, improves the disease development in an acute experimental model of BPM. The experimental pathology was induced by trans-tracheal inoculation of M. haemolytica and toxins at T0. One hour post-inoculation, six calves were treated intravenously with carprofen (1,4 mg/kg) while six placebo-treated calves received dose-matched volumes of sterile saline. The clinical and biochemical parameters were measured at one (T+1), three (T+3) and seven (T+7) hours after inoculation. Disease scores for carprofen treated calves were significantly lower than those for placebo-treated controls six hours (T+7) after treatment. These results were associated to a significantly oxygen saturation decrease at T+3 and a significantly blood lactate increase at T+7 in the control calves. Moreover, pulmonary lesions were significantly less extensive than those in the control group. Taken together, this finding suggest that pharmacological modulation by carprofen of pulmonary inflammation after appearance of acute BPM clinical signs leads to calves’ health enhancement and reduces the extent of gross pneumonic lesion. [less ▲]

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See detailCaractériser un profil inflammatoire grâce à l'utilisation du microdamier
Ramery, Eve ULg; Closset, Rodrigue; Bureau, Fabrice ULg et al

Poster (2007)

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See detailIdentification de gènes d'intérêt pour le traitement du cheval poussif
Ramery, Eve ULg; Closset, Rodrigue; Salinas, Emmanuelle et al

in Proceedings: AVEF, Versailles, France (2006)

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See detailLe nez électronique, un nouvel outil diagnostique pour les maladies respiratoires du cheval ?
Salinas, Emmanuelle; Ramery, Eve ULg; Fraipont, Audrey ULg et al

in Proceedings: AVEF, Versailles, France (2006)

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