References of "REGINSTER, Jean-Yves"
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See detailStrontium Ranelate: A New Treatment for Postmenopausal Osteoporosis with a Dual Mode of Action
Reginster, Jean-Yves ULiege; Sarlet, Nathalie ULiege; LEJEUNE, Eric ULiege et al

in Current Osteoporosis Reports (2005), 3(1), 30-4

In vitro, strontium ranelate increases collagen and noncollagen protein synthesis by mature osteoblast-enriched cells. Its effects on bone formation were confirmed as the drug enhanced preosteoblastic ... [more ▼]

In vitro, strontium ranelate increases collagen and noncollagen protein synthesis by mature osteoblast-enriched cells. Its effects on bone formation were confirmed as the drug enhanced preosteoblastic cell replication. In the isolated osteoclast, preincubation of bone slices with strontium ranelate-induced dose-dependent inhibition of the bone-resorbing activity of treated rat osteoclast. Strontium ranelate dose-dependently inhibited preosteoclast differentiation. Its effect in postmenopausal women with established osteoporosis was assessed during an international, prospective, double-blind, randomized, placebo-controlled phase 3 program comparing strontium ranelate 2 g daily with placebo. The 3-year analysis of the phase 3 study, Spinal Osteoporosis Therapeutic Intervention, evaluating the effect of strontium ranelate 2 g/day on vertebral fracture rates, revealed a significant 41% reduction in the relative risk of patients experiencing new vertebral fracture with strontium ranelate over 3 years. A second phase 3 study showed a significant reduction in the relative risk of experiencing a nonvertebral fracture in the group treated with strontium ranelate over 3 years. These results show that strontium ranelate is a new, effective, and safe treatment for vertebral and hip osteoporosis, with a unique mode of action, increasing bone formation and decreasing bone resorption leading to a rebalance of bone turnover in favor of bone formation. [less ▲]

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See detailAnalysis of the discriminant ability of shorter versions of the French ADAM questionnaire
Tancredi, Annalisa ULiege; Legros, Jean-Jacques ULiege; Pire, George et al

in Osteoporosis International (2005, March), 16(Suppl.3), 39

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See detailShort-term daily administration of 1500 mg glucosamine contributes to symptomatic improvement of osteoarthritis
Reginster, Jean-Yves ULiege; Imschoot, J.; Ghys, A.

in Osteoporosis International (2005, March), 16(Suppl.3), 33

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See detailPhysical functionning is the most severely affected health-related quality of life dimension during the aging process
Ethgen, Olivier ULiege; Gosset, Christiane ULiege; De Maeseneer, J. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 25-26

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See detailAge- and sex-stratified prevalence of physical disabilities and handicap in the general population
Ethgen, Olivier ULiege; GILLAIN, Daniel ULiege; Gillet, Pierre ULiege et al

in Osteoporosis International (2005, March), 16(Suppl.3), 25

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See detailIndirect costs induced by osteoarthritis and osteoporosis in the workplace
Rabenda, Véronique ULiege; MANETTE, Christine ULiege; Lemmens, R. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 13-14

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See detailEstimation of direct unit costs associated with non-vertebral osteoporotic fractures in six European countries
Bouée, S.; Lafuma, A.; Fagnani, F. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 13

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See detailThe effects of teriparatide on the risk of back pain in men and women with osteoporosis: A meta-analysis
Reginster, Jean-Yves ULiege; Chen, P.; Dore, R. K. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 10-11

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See detailIntermittent intravenous ibandronate injections and daily oral ibandronate provide at least equivalent increases in bone mineral density: 1-year results from DIVA
Delmas, P. D.; Sambrook, P.; Recker, R. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 7

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See detailVertebral and non-vertebral anti-fracture efficacy of strontium ranelate in very elderly women with osteoporosis
Seeman, E.; Vellas, B.; Meunier, Pierre J et al

in Osteoporosis International (2005, March), 16(Suppl.3), 6

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See detailIdentification of responders to teriparatide therapy by procollagen Type I N-Propeptide (P1NP) using the least significant change approach
Eastell, R.; Chen, P.; Krege, J. H. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 5

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See detailScreening for osteoporosis: systematic DXA or pre-screening with questionnaires? An economic point of view
Richy, Florent; Ethgen, Olivier ULiege; Bruyère, Olivier ULiege et al

in Osteoporosis International (2005, March), 16(Suppl.3), 101

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See detailResponders to glucosamine sulfate in knee osteoarthritis
Bruyère, Olivier ULiege; Pavelka, K.; Richy, Florent et al

in Osteoporosis International (2005, March), 16(Suppl.3), 77

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See detailA critical analysis of the efficacy of estrogens on spinal and non-spinal fracture reduction
Reginster, Jean-Yves ULiege; Richy, Florent; Bruyère, Olivier ULiege

in Osteoporosis International (2005, March), 16(Suppl.3), 47

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See detailOne-year progression of knee osteoarthritis: correlations between X-Rays and magnetic resonance imaging changes
Bruyère, Olivier ULiege; Kothari, M.; Zaim, S. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 46-47

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See detailFemoro-tibial joint space width, assessed by standard X-Ray, is associated with tibial cartilage volume and thickness, assessed by magnetic resonance imaging
Bruyère, Olivier ULiege; Kothari, M.; Zaim, S. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 46

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See detailAn indirect comparison of the efficacies of vitamin D and its hydroxylated analogs in postmenopausal and corticosteroid-induced osteoporosis
Richy, Florent; Schacht, E.; Bruyère, Olivier ULiege et al

in Osteoporosis International (2005, March), 16(Suppl.3), 29

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See detailKnee whole-organ MRI score (WORMS) as a surrogate marker for X-ray joint space narrowing
Bruyère, Olivier ULiege; Kothari, M.; Zaim, S. et al

in Osteoporosis International (2005, March), 16(Suppl.3), 6

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