References of "REGINSTER, Jean-Yves"
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See detailNumerus clausus en fin de troisieme candidature en medecine: mort annoncee d'une heresie?
Rabenda, Véronique ULg; Boniver, Jacques ULg; Reginster, Jean-Yves ULg

in Revue Médicale de Liège (2003), 58(7-8, Jul-Aug), 508-14

Owing to the establishment of a procedure aiming at a reduction of the medical supply (numerus clausus), the French Community of Belgium had decided to introduce, at the end of the third year of medical ... [more ▼]

Owing to the establishment of a procedure aiming at a reduction of the medical supply (numerus clausus), the French Community of Belgium had decided to introduce, at the end of the third year of medical studies (third candidature), a procedure of selective attribution of the certificate allowing for a unlimited medical practice. We assessed the predictive value of the results obtained during and at the end of the first candidature (first year of medicine) for the attribution of this certificate. We studied the results of the 225 students enrolled in the first candidature in medicine at the University of Liege during the academic year 1997-1998, and we correlated them to the subsequent attribution (1999-2000- and 2000-2001) of the certificate. The success of the first candidature in the first or second session is an important predicting factor towards the reception of the certificate. A non-authorization to continue the studies in medicine in case of failure in the first session or a non-authorization to repeat the first candidature in case of failure in the second session would have, respectively, a negative predictive value (NPV) of 91.9% and 97.4% and would allow to restream 111 students at the end of the first session or 39 students at the end of the first candidature. The results of the preliminary assessments mode during the month of January are also highly predictive of the chances to get the certificate. Among the 160 students who have not successfully passed a minimum of 3 exams, only 14 students obtained the certificate. The restreaming of those students would correspond to a NPV of 91.2%. Students who were not successful in a minimum of 2 exams would have less than 5% chance to obtain the certificate. In this case, 109 students would be restreamed (NPV = 95.4%). In conclusion, the selection of the students who will obtain, at the end of the third year of medicine, the certificate allowing them for an unlimited medical practice is obtained, in a large proportion, during the first candidature and especially after the session of January. In view of those results and considering the decree abolishing the selection at the end of the third year of medical studies, one could argue about the appropriateness of the current procedure, chosen by the French Community of Belgium, compared to other solutions prioritising an earlier selection of the future doctors. [less ▲]

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See detailPrevention of early postmenopausal bone loss by strontium ranelate: The randomized, two-year, double-masked, dose-ranging, placebo-controlled PREVOS trial
Reginster, Jean-Yves ULg; Deroisy, Rita ULg; Dougados, M. et al

in Osteoporosis International (2002), 13(12), 925-931

Early postmenopausal women (n = 160) were randomised to receive placebo or strontium ranelate (SR) 125 mg/day, 500 mg/day or 1 g/day for 2 years (40 participants per group). All participants received ... [more ▼]

Early postmenopausal women (n = 160) were randomised to receive placebo or strontium ranelate (SR) 125 mg/day, 500 mg/day or 1 g/day for 2 years (40 participants per group). All participants received calcium 500 mg/day. The primary efficacy parameter was the percent variation in lumbar bone mineral density (BMD), measured using dual-energy X-ray absorptiometry. Secondary efficacy criteria included hip BMD and biochemical markers of bone turnover. At month 24, SR I g/day significantly increased lumbar BMD compared with placebo [mean (SD) +5.53% (5.12); p < 0.001] for measured values and [mean (SD) + 1.41% (5.33%); p < 0.05] for values adjusted for bone strontium content. The annual increase for adjusted values was +0.66% compared with -0.5% with placebo, with an overall beneficial effect after 2 years of about 2.4% with SR I g/day relative to placebo. There were no other significant between-group differences in adjusted lumbar BMD. Femoral neck and total hip BMD were also significantly increased at month 24 with SR I g/day compared with placebo [mean (SD): +2.46% (4.78) and +3.21% (4.68), respectively; both p < 0.001)]. SR 1 g/day significantly increased bone alkaline phosphatase at all time points (p < 0.05) compared with baseline and between-group analysis showed a significant increase, compared with placebo, at month 18 (p = 0.048). No effect on markers of bone resorption was observed. SR was as well tolerated as placebo. The minimum does at which SR is effective in preventing bone loss in early postmenopausal non-osteoporotic women is therefore 1 g/day. [less ▲]

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See detailDevelopment of the Osteoporosis Risk Assessment by Composite Linear Essay (ORACLE)
Richy, Florent; Uhoda, Emmanuelle ULg; Reginster, Jean-Yves ULg

in Osteoporosis International (2002, November), 13(Suppl.3), 11

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See detailStructure modifying drugs in osteoarthritis
Reginster, Jean-Yves ULg; Kvasz, A.

Conference (2002, November)

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See detailL'evaluation de la qualite de vie dans les essais therapeutiques: un pas vers une approche holistique de la sante
Ethgen, Olivier ULg; Reginster, Jean-Yves ULg

in Revue Médicale de Liège (2002), 57(11), 695-700

The concept of quality of life has been widely developed over the last two decades. As they provide subjective assessment of health, quality of life measures may be broadly and relevantly applied in many ... [more ▼]

The concept of quality of life has been widely developed over the last two decades. As they provide subjective assessment of health, quality of life measures may be broadly and relevantly applied in many areas. Numerous measures are available today to perform discriminative, evaluative or analytical studies in the epidemiological, the therapeutic or the health economic fields. Such measures are increasingly used and may be added to clinical, biological or radiographical criteria to assess medical benefits and health outcomes in order to strengthen decisional choice in health. [less ▲]

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See detailStrontium ranelate treatment prevents health related quality of life impairement in results from the SOTI study
Marquis, P.; De la Loge, C.; Roux, Christian et al

in Osteoporosis International (2002, November), 13(Suppl.3), 11

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See detailClinical severity of knee osteoarthritis poorly predicts long-term radiographic outcomes
Bruyère, Olivier ULg; Ethgen, Olivier ULg; Lejeune, Eric ULg et al

in Osteoporosis International (2002, November), 13(Suppl.3), 51

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See detailSubchondral tibial bone mineral density predicts joint space narrowing at the medial femoro-tibial compartment in patients with knee osteoarthritis
Bruyère, Olivier ULg; Lambert, V.; Dardenne, C. et al

in Osteoporosis International (2002, November), 13(Suppl.3), 51-52

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See detailInhaled corticosteroids effects on bone in asthmatic and COPD patients: what is the evidence?
Richy, Florent; Bousquet, Jean; Devogelaer, Jean-Pierre et al

in Osteoporosis International (2002, November), 13(Suppl.3), 22

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See detailPain relief is not a confounder in joint space narrowing assessment of full extension knee radiographs in osteoarthritis structure-modifying drug trials
Pavelka, K.; Rovati, Lucio C; Gatterova, J. et al

in Osteoporosis International (2002, November), 13(Suppl.3), 19-20

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See detailStructural and symptomatic efficacy of glucosamine and chondroitine sulfate in osteoarthrits: a comprehensive meta-analysis
Richy, Florent; Bruyère, Olivier ULg; Ethgen, Olivier ULg et al

in Osteoporosis International (2002, November), 13(Suppl.3), 55-56

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See detailMusculoskeletal disorders in a time demographic changes: a real challenge for the future in Europe and Northern America
Ethgen, Olivier ULg; Richy, Florent; De Ceulaer, F. et al

in Osteoporosis International (2002, November), 13(Suppl.3), 48-49

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See detailIs there any rationale for prescribing hormone replacement therapy (HRT) to prevent or to treat osteoarthritis?
Kvasz, Angela ULg; Bruyère, Olivier ULg; Neuprez, Audrey ULg et al

in Osteoporosis International (2002, November), 13(Suppl.3), 59

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See detailStrontium ranelate reduces the risk of hip fracture in women with postmenopausal osteoporosis
Reginster, Jean-Yves ULg; Sawicki, A.; Devogelaer, Jean-Pierre et al

in Osteoporosis International (2002, November), 13(Suppl.3), 14

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See detailThe urinary levels of type II collagen peptide COLL 2-1 and its nitrated form (COLL 2-1 NO2) are correlated with the clinical severity of knee osteoarthritis
Deberg, Michelle ULg; Christgau, Stephan; Henriksen, Dennis Bang et al

in Osteoporosis International (2002, November), 13(Suppl.3), 54

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