References of "Quetin-Leclercq, Joëlle"
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See detailToxic and mitogenic activities of culture media conditioned by B16 melanoma cells
Coucke, Paul; Siwek, Brigitte; Gillet, Marie-Claire ULg et al

Conference (1990)

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See detailAn indolinic cryptoalkaloid from Strychnos mattogrossensis
Angenot, Luc ULg; Belem-Pinheiro, Maria-Lucia; Imbiriba da Rocha, Arnaldo et al

in Phytochemistry (1990), 29(8), 2746-2749

A new indolinic cryptoalkaloid, mattogrossine, has een isolated from the roots and branches of Strychnos mattogrossensis collected near Manaus. Elucidation of its structure is based mainly on 2D NMR ... [more ▼]

A new indolinic cryptoalkaloid, mattogrossine, has een isolated from the roots and branches of Strychnos mattogrossensis collected near Manaus. Elucidation of its structure is based mainly on 2D NMR studies. Two other indolinic alkaloids were also obtained: strychnobrasiline and 12-hydroxy-11-methoxystrychnobrasiline, and their 13C NMR data are provided [less ▲]

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See detailVenecurine, an Indole Alkaloid from Curare
Quetin-Leclercq, Joëlle; Warin, Roger; Bisset, Norman et al

in Phytochemistry (1989), 28(9), 2221-2223

A new quaternary indole alkaloid, venecurine, has been isolated by chromatographic techniques from a curare obtained from the Hoti tribe of Venezuela. Elucidation of its structure is based mainly on 2D ... [more ▼]

A new quaternary indole alkaloid, venecurine, has been isolated by chromatographic techniques from a curare obtained from the Hoti tribe of Venezuela. Elucidation of its structure is based mainly on 2D-NMR studies. Concurrently with the structural work, frog bioassays were carried out. The curare and venecurine exhibit the same type of activity that is relatively low as compared with the dimeric curarizing alkaloids.These results may be an indication that the sample of curare investigated was a weak one intended to be used for capturing rather than killing animals. [less ▲]

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See detail10-Hydroxy-Nb-methyl-corynantheol, a new quaternary alkaloid from the stem bark of Strychnos usambarensis
Quetin-Leclercq, Joëlle; Angenot, Luc ULg

in Phytochemistry (1988), 27(6), 1923-1926

A new quaternary indole alkaloid: 10-hydroxy-Nb-methyl-corynantheol has been isolated from the stem bark of Strychnos usambarensis by High Speed Counter Current Chromatography (HSCCC). Its IUPAC name is 2 ... [more ▼]

A new quaternary indole alkaloid: 10-hydroxy-Nb-methyl-corynantheol has been isolated from the stem bark of Strychnos usambarensis by High Speed Counter Current Chromatography (HSCCC). Its IUPAC name is 2-(2-hydroxyethyl)-3-vinyl-5-methyl-1,2,3,4,6,7,12,12b-octahydro-indolo quinolizinium-9-ol. The structure was established by spectral (UV,IR,EIMS and NMR data) and chemical methods.The stereochemistry was proposedo n the basis of CD curve, NMR studies and biogenetic hypothesis. [less ▲]

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See detailIsolation and Purification of Panarine, a Quaternary Alkaloid from a Venezuelian Curare
Quetin-Leclercq, Joëlle; Angenot, Luc ULg; Dupont, Léon et al

in Phytochemistry (1988), 27(12), 4002-4004

High Speed Counter Current Chromatography (HSCCC) has been used to isolate and purify two quaternary alkaloids from a sample of curare prepared by the Panare Indians of Estado Bolivar, Venezuela. One of ... [more ▼]

High Speed Counter Current Chromatography (HSCCC) has been used to isolate and purify two quaternary alkaloids from a sample of curare prepared by the Panare Indians of Estado Bolivar, Venezuela. One of the compounds is the known base Macusine B. The other one is a new but related base named panarine. Its structure has been established unequivocally by spectral and X-ray cristallographic analysis. [less ▲]

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See detailAlkaloids of Rauwolfia sellowii from Amazonia
Belem-Pinheiro, Maria-Lucia; Imbiriba da Rocha, Arnaldo; Quetin-Leclercq, Joëlle et al

in Journal de Pharmacie de Belgique (1988), 43(5), 379-381

Reserpiline, sarpagine, lochnerine, harman and beta-yohimbine were the main alkaloids identified in the bark of Rauwolfia sellowii collected in Amazonia. This chemical race could be used for the ... [more ▼]

Reserpiline, sarpagine, lochnerine, harman and beta-yohimbine were the main alkaloids identified in the bark of Rauwolfia sellowii collected in Amazonia. This chemical race could be used for the commercial preparation of reserpiline, which is included in various pharmaceutical proprietary preparations used as antihypertensive. [less ▲]

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See detailStrychnochromine, an unusual C18 indoline alkaloid from Strychnos gossweileri
Angenot, Luc ULg; Coune, Claude; Quetin-Leclercq, Joëlle et al

in Phytochemistry (1988), 27(2), 595-597

Through a combination of spectroscopic techniques (UV, IR, MS, 1H and 13C NMR) it has been possible to propose a plane structure and the relative configuration of strychnochromine a dextrorotatory ... [more ▼]

Through a combination of spectroscopic techniques (UV, IR, MS, 1H and 13C NMR) it has been possible to propose a plane structure and the relative configuration of strychnochromine a dextrorotatory alkaloid isolated from the root bark of Strychnos gossweileri. [less ▲]

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See detailAlkaloids of Rauwolfia sellowii from Amazonia
Belem-Pinheiro, Maria-Lucia; Imbiriba da Rocha, Arnaldo; Quetin-Leclercq, Joëlle et al

in Fitoterapia (1988), 59(5), 429

Five indole alkaloids ( reserpiline, sarpagine, lochnerine, harman, beat-yohimbine) are identified in the root bark of Rauwolfia sellowii collected for the first time in Amazonian forest (Rio Branco, Acre ... [more ▼]

Five indole alkaloids ( reserpiline, sarpagine, lochnerine, harman, beat-yohimbine) are identified in the root bark of Rauwolfia sellowii collected for the first time in Amazonian forest (Rio Branco, Acre). [less ▲]

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See detailAntimitotic and cytotoxic Activities of Guattegaumerine, a Bisbenzylisoquinoline Alkaloid
Quetin-Leclercq, Joëlle; Gillet, Marie-Claire ULg; Bassleer, Roger et al

in Planta Medica (1987), 53

Guattegaumerine was isolated from the bark of Guatteria gaumeri ( cf Dehaussy, Tits and Angenot, Planta Med. (1983) 49, 25-27) , a medicinal plant called Yumel in Yucatan (South Mexico).Guattegaumerine ... [more ▼]

Guattegaumerine was isolated from the bark of Guatteria gaumeri ( cf Dehaussy, Tits and Angenot, Planta Med. (1983) 49, 25-27) , a medicinal plant called Yumel in Yucatan (South Mexico).Guattegaumerine exerts a good activity at 5 micrograms/ml on B16 melanoma which is a relatively resistant tumor. It is less active against 2002 cells that are normal human cells. [less ▲]

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