References of "Quatresooz, Pascale"
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See detailLe cas clinique du mois. Erytheme polymorphe sur infection a Mycoplasma
Maquet, Julien ULg; Strull, N.; Quatresooz, Pascale ULg et al

in Revue Médicale de Liège (2008), 63(1), 6-10

Erythema multiforme (EM) is an immune-mediated disease categorized into EM minor and EM major, also called Stevens-Johnson syndrome (SJS), not to be confused with toxic epidermal necrosis (TEN), as ... [more ▼]

Erythema multiforme (EM) is an immune-mediated disease categorized into EM minor and EM major, also called Stevens-Johnson syndrome (SJS), not to be confused with toxic epidermal necrosis (TEN), as physiopathological pathways are throughly different. Mycoplasma pneumoniae is an intracellular germ, generally responsible for atypical respiratory infections. It may be associated with erythema multiforme, eventually recurrent, illustrated by the present case report. [less ▲]

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See detailDeciphering Langer’s lines using dermoscopy.
QUATRESOOZ, Pascale ULg

Conference (2008)

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See detailLaddering melanotic pattern of Langer's lines in skin of colour.
Quatresooz, Pascale ULg; Hermanns, Jean-Francois; Hermanns-Lê, Trinh ULg et al

in European Journal of Dermatology (2008), 18(5), 575-8

Mechanobiological stimulation of the skin influences melanocyte activity. The clinical impact on melanocytes can be perceived by dermoscopy. Our aim was to assess the orientation of Langer's lines using ... [more ▼]

Mechanobiological stimulation of the skin influences melanocyte activity. The clinical impact on melanocytes can be perceived by dermoscopy. Our aim was to assess the orientation of Langer's lines using the combination of ultrasound shear wave propagation and dermoscopy in 70 adults of darker skin complexion. On the back, 44/70 patients showed a honeycomb melanotic pattern without any main orientation. By contrast, a streaky parallel pattern of melanotic lines oriented in the direction of Langer's lines was found in 26/70 patients. Indeed, the maximum speed of ultrasound propagation was found parallel to the main orientation of the laddering melanotic pattern. The parallel melanotic pattern probably reflects the main orientation of the epidermal rete ridges aligned in the direction of Langer's lines. This aspect could be ascribed to the deepening of these structures and/or to mechanobiology affecting melanocytes. The aspect is reminiscent of that previously described in striae distensae and atrophic scars. [less ▲]

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See detailMolecular mapping of Factor XIIIa-enriched dendrocytes in the skin (Review).
Quatresooz, Pascale ULg; Paquet, Philippe ULg; Hermanns-Lê, Trinh ULg et al

in International Journal of Molecular Medicine (2008), 22(4), 403-9

The human dermis contains a series of dendritic cells which express different phenotypes including Factor XIIIa immunoreactivity. This compound is related to a blood coagulation factor participating in ... [more ▼]

The human dermis contains a series of dendritic cells which express different phenotypes including Factor XIIIa immunoreactivity. This compound is related to a blood coagulation factor participating in angiogenesis, in the final stages of the clotting cascade and in wound healing. In normal skin, Factor XIIIa is expressed in specific dermal dendrocytes (DD) derived from the monocyte/macrophage lineage or from a mesenchymal origin. DD are located predominantly around the microvasculature in the adventitial dermis, at the dermo-epidermal junction, and around skin appendages, but normally not within the epidermis. Increased numbers of Factor XIIIa+ DD are present in a host of specific cutaneous inflammatory and fibrotic conditions. In tumor pathology, immunophenotypic differences are found between dermatofibromas and other fibrohistiocytic entities, most notably dermatofibrosarcoma protuberans. In addition, Factor XIIIa+ DD are likely to be involved in the progression and regression of some malignancies including cutaneous melanoma and basal cell carcinoma. [less ▲]

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See detailHedgehog ringworm in humans and a dog.
Pierard-Franchimont, Claudine; Hermanns, Jean-François ULg; Collette, C. et al

in Acta Clinica Belgica (2008), 64

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See detailPorokératoses verruqueuses multipes.
ARRESE ESTRADA, Jorge ULg; QUATRESOOZ, Pascale ULg; AL RUSTOM, K. et al

in Dermatologie Actualité (2008), 106

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See detailEstablished and emerging oral antifungals in dermatology
PIERARD, Gérald ULg; PIERARD-FRANCHIMONT, Claudine ULg; vroome, v et al

in Dermatologic, cosmeceutic and cosmetic development (2008)

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See detailDes vérités diagnostiques à la réalité
QUATRESOOZ, Pascale ULg; PIERARD, Gérald ULg

Scientific conference (2008)

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See detailLe fond de l'air est frais, le froid est piquant et la peau en pâtit.
Quatresooz, Pascale ULg; Pierard, Claudine ULg; Paquet, Philippe ULg et al

in Revue Médicale de Liège (2008), 63(1), 18-22

Contrasting with many animals, the human physiological capacity to resist to cold is quite limited. Severe cold exerts its major physiopathological effects on the skin and the whole body. The skin and ... [more ▼]

Contrasting with many animals, the human physiological capacity to resist to cold is quite limited. Severe cold exerts its major physiopathological effects on the skin and the whole body. The skin and body thermoregulations become quite rapidly unsatisfactory. Cold is then responsible for a series of dermatoses which could, however, be often prevented by simple means. The severity and the duration of exposure to cold, combined to wind speed, altitude and environmental hygrometry condition the nature and severity of the potential disorders. Some lesions may remain moderate in severity, self-limited and transitory. Others lead to irreversible damage with necrosis of the skin and the deeper tissues. Death secondary to hypothermia is the risk of performing some outdoor activities in inhospitable and extreme cold conditions. [less ▲]

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See detailLe melanome cutane: innovations conceptuelles et therapeutiques, fruit de la recherche translationnelle.
Pierard, Gérald ULg; Quatresooz, Pascale ULg; Rorive, Andrée ULg et al

in Revue Médicale de Liège (2008), 63(10), 579-84

The scientific information about melanoma is on the rise. It has a direct impact on the diagnostic acuteness and on the therapeutic management. The most recent aspects of the utmost importance are ... [more ▼]

The scientific information about melanoma is on the rise. It has a direct impact on the diagnostic acuteness and on the therapeutic management. The most recent aspects of the utmost importance are presented. The concept of the duality between fast-growing (high malignancy) and slow-growing (reduced malignancy) melanoma is stressed. A new international multicentric approach using adjuvant therapy for stage III melanomas involves the clinical oncology department of the CHU of Liege. It concerns a targeted immunotherapy directed to the Mage A3 protein. [less ▲]

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See detailComment j'explore... une metastase cutanee. Qui es-tu, d'ou viens-tu?
Quatresooz, Pascale ULg; Pierard, Claudine ULg; Rorive, Andrée ULg et al

in Revue Médicale de Liège (2008), 63(9), 559-63

Cutaneous metastases may accompany up to 3 to 10% of all malignancies. They are usually identified after diagnosing the primary neoplasm. However, their disclosure can be synchronous, or the metastasis ... [more ▼]

Cutaneous metastases may accompany up to 3 to 10% of all malignancies. They are usually identified after diagnosing the primary neoplasm. However, their disclosure can be synchronous, or the metastasis may be the initial finding qualified as "precocious". The identification of the primary neoplasm sometimes proves to be difficult. Gender of the patient, the aspect and distribution of the metastases, as well as the histological and immunohistological examinations help establishing the diagnosis. The prognosis of the metastatic disease is often poor. [less ▲]

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See detailLe cas clinique du mois. Pemphigoide bulleuse apres brulure thermique.
Blaise, G.; Pierard, Claudine ULg; Quatresooz, Pascale ULg et al

in Revue Médicale de Liège (2008), 63(4), 182-3

In rare instances, some injuring physical factors such as thermal burns can be at the origin of bullous pemphigoid lesions. The early lesions are most often restricted to the injured skin area. Secondary ... [more ▼]

In rare instances, some injuring physical factors such as thermal burns can be at the origin of bullous pemphigoid lesions. The early lesions are most often restricted to the injured skin area. Secondary generalization is the natural evolution to be expected. However, once the episode is resolved, recurrence is exceptional. When the natural history of bullous pemphigoid differs from the regular type, the peculiar condition of development of these lesions does not change any of the diagnostic clinical and histological criteria, as well as the therapeutic procedures to follow. [less ▲]

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See detailLa peau et ses principales neurocristopathies.
Quatresooz, Pascale ULg; Vandenbossche, Géraldine ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2008), 63(5-6), 354-8

The neurocristopathies encompass genetic disorders targeting some structures originating from the neural crest development. Hence, skin is affected by some clinical manifestations of these disorders. This ... [more ▼]

The neurocristopathies encompass genetic disorders targeting some structures originating from the neural crest development. Hence, skin is affected by some clinical manifestations of these disorders. This review covers the main aspects found in neurofibromatosis, tuberous sclerosis, incontinentia pigmenti, neurocutaneous melanoblastosis, basal cell naevomatosis and the epidermal naevus syndrome. [less ▲]

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See detailComment j'explore... un lymphome T cutane. Nouveaux horizons.
Quatresooz, Pascale ULg; Pierard, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2008), 63(4), 208-12

Although cutaneous T cell lymphomas remain rare, their incidence seems progressively on the rise. The main diagnostic criteria are issued from the clinico-pathological confrontation. Other methods help ... [more ▼]

Although cutaneous T cell lymphomas remain rare, their incidence seems progressively on the rise. The main diagnostic criteria are issued from the clinico-pathological confrontation. Other methods help support the diagnosis and establish a prognosis. [less ▲]

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See detailL'image du mois. Tinea incognito.
Vandenbossche, Géraldine ULg; Legrain, A.; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2008), 63(7-8), 463-4

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See detailComment j'explore...Un patient avec un erytheme palmaire.
Vandenbossche, Géraldine ULg; Pierard, Claudine ULg; Quatresooz, Pascale ULg et al

in Revue Médicale de Liège (2008), 63(2), 101-4

Palmar erythema occurs in a series of physiological and pathological conditions. The first group encompasses hereditary and idiopathic conditions, as well as the time of pregnancy and ageing. The ... [more ▼]

Palmar erythema occurs in a series of physiological and pathological conditions. The first group encompasses hereditary and idiopathic conditions, as well as the time of pregnancy and ageing. The pathological states include some dermatoses as well as hepatic, autoimmune, infectious and paraneoplastic conditions. Medications may also be responsible for palmar erythema, in particular some chemotherapy agents. [less ▲]

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See detailBiometrology of physical properties of skin in thyroid dysfunction.
Szepetiuk, Grégory ULg; Pierard, Gérald ULg; Betea, Daniela ULg et al

in Journal of the European Academy of Dermatology & Venereology (2008), 22(10), 1173-1177

OBJECTIVE: There is ample clinical evidence that skin is responsive to physiopathological levels of circulating thyroid hormones. The aim of the study was to assess some physical changes of the skin in ... [more ▼]

OBJECTIVE: There is ample clinical evidence that skin is responsive to physiopathological levels of circulating thyroid hormones. The aim of the study was to assess some physical changes of the skin in the presence of moderate thyroid dysfunction. SETTING: University Hospital. PATIENTS AND METHODS: A total of 119 adults suffering from hypothyroidism or hyperthyroidism and 60 healthy controls were enrolled in this study. Hormonal dosages (TSH, fT3, fT4) were assessed in the serum. A series of biometrological assessments were also performed on the volar and dorsal aspects of the forearms. These included electrometric assessments (Nova Dermal Phase Meter, Corneometer), evaporimetry (Tewameter)), colorimetry (Mexameter), ultrasound shear wave propagation (Reviscometer) and squamometry X. Correlations were searched between each of the serum hormonal dosages and each of the biometrological parameters. RESULTS: The hormonal changes in the untreated patients with thyroid dysfunction were modest in intensity. A few outlier values with regard to the normal range were found for each biometrological parameter. No correlations were found between fT3 or fT4 and each of the physical parameters. By contrast, significant negative linear correlations were found between thyroid-stimulating hormone (TSH) and skin hydration measured by the Corneometer and the Nova DPM. CONCLUSION: This multipronged exploratory study shows that direct or indirect effects of TSH may influence the stratum corneum hydration. This correlation seemed very sensitive, as no other specific biophysical parameter was significantly correlated with the thyroid hormonal concentrations in the serum. However, our findings do not exclude the possibility of some other skin changes supervening in case of more severe thyroid dysfunction. The mechanism by which TSH alters the stratum corneum hydration is yet unknown. [less ▲]

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