References of "Pirotte, Bernard"
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See detailStereoselective hydrogenation of methacycline to doxycycline catalysed by rhodium-carborane complexes
Fontaine, M.; Demonceau, Albert ULg; Noels, A. F. et al

Poster (1993, July)

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See detailNew inhibitors of serine proteinases
Jiang, K. Y.; Schynts, M.; Fesquet, S. et al

Poster (1993, June)

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See detailLoop diuretics and the renal Na+K+2Cl- cotransport: interaction model
Masereel, B.; Schynts, M.; Pirotte, Bernard ULg et al

Conference (1993, March)

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See detailStereoselective hydrogenation of methacycline to doxycycline catalysed by rhodium-carborane complexes
Pirotte, Bernard ULg; Felekidis, Apostolos ULg; Fontaine, M. et al

in Tetrahedron Letters (1993), 34

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See detailImproved pancreatic K-ATP channel openers belonging to the pyridothiadiazine chemical class
Pirotte, Bernard ULg; De Tullio, Pascal ULg; Lebrun, P. et al

in Journal de Pharmacie de Belgique (1993), 48

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See detailBPDZ 44: a new and potent activator of ATP-sensitive K+ channels
Lebrun, P.; Pirotte, Bernard ULg; Antoine, M.-H. et al

in Diabetologia (1993), 36

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See detailLoop diuretics and the renal Na+K+2Cl- cotransport: interaction model
Masereel, B.; Schynts, M.; Pirotte, Bernard ULg et al

in Journal de Pharmacie de Belgique (1993), 48

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See detailA sulfonylthiourea (BM 20) related to torasemide: a new loop diuretic with relative potassium-sparing properties
Masereel, B.; Schynts, M.; Krzesinski, Jean-Marie ULg et al

in Journal of Pharmacy & Pharmacology (1993), 45

A series of sulphonylthioureas related to torasemide, a high ceiling loop diuretic, were synthesized and found to inhibit the Na+ 2Cl- K+ co-transporter of the thick ascending limb of the loop of Henlé ... [more ▼]

A series of sulphonylthioureas related to torasemide, a high ceiling loop diuretic, were synthesized and found to inhibit the Na+ 2Cl- K+ co-transporter of the thick ascending limb of the loop of Henlé. Their diuretic properties were studied (30 mg kg-1) after oral administration to rats. Lipophilic derivatives very active in-vitro, were found inactive orally and intraperitoneally in rats. The four most active compounds were examined for their dose-dependent diuresis. Three of them showed a potency, water and electrolyte excretion similar to torasemide. The fourth molecule, a sulphonylthiourea (BM 20), exhibited relative potassium-sparing properties and a minimal diuretic dose of 0.001 mg kg-1, 200 times lower than torasemide. [less ▲]

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See detailNew dihydrocoumarine derivatives as potential mechanism-based inactivators of serine proteinases
Schynts, M.; Boggetto, N.; Masereel, B. et al

Poster (1992, November 06)

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See detailStereoselective hydrogenation of methacycline to doxycycline catalysed by rhodium-carborane complexes
Fontaine, M.; Demonceau, Albert ULg; Noëls, A. F. et al

Poster (1992, November)

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See detailsynthesis of sulfonylthioureas related to torasemide as new "high ceiling diuretics
Masereel, B.; Schynts, M.; Pirotte, Bernard ULg et al

Poster (1992, July)

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See detailNew relative K+-sparing high ceiling diuretics related to torasemide
Masereel, B.; Schynts, M.; Lohrmann, E. et al

Conference (1992)

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See detailAction of diuretics at the cellular level
Lohrmann, E.; Masereel, B.; Nitschke, R. et al

in Progress in Pharmacology and Clinical Pharmacology (1992)

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