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	References of "Pirotte, Bernard" in Showing results 41 to 60 of 672 1 2 3 4 5 6 7 8 Ring-fused thiadiazines as core structures for the development of potent AMPA receptor potentiators Pirotte, Bernard ; Francotte, Pierre ; Goffin, Eric et al in Current Medicinal Chemistry (2010), 17 Detailed reference viewed: 24 (5 ULg) Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs? Robert, S.; Ghiotto, J.; Pirotte, Bernard et al Conference (2009, November) Detailed reference viewed: 13 (1 ULg) Preparation of cycloalkylated benzothiadiazine derivatives and their use as AMPA receptor modulators Francotte, Pierre ; De Tullio, Pascal ; Pirotte, Bernard et al Patent (2009) Detailed reference viewed: 2 (1 ULg) Original cromakalim analogues as KATP channel openers Florence, X.; De Tullio, Pascal ; Pirotte, Bernard et al Conference (2009, June) Detailed reference viewed: 5 (0 ULg) Developpement d’inhibiteurs de cyclooxygénases: les analogues pyridiniques du nimésulide Renard, Jean-François ; Arslan, Deniz ; Garbacki, Nancy et al Poster (2009, May) Detailed reference viewed: 14 (4 ULg) Stabilisation métabolique par introduction d’atomes de fluor : application aux benzothiadiazine 1,1-dioxydes agissant en tant que potentialisateurs AMPA Francotte, Pierre ; Fraikin, Pierre; Goffin, Eric et al Poster (2009, May) Detailed reference viewed: 9 (1 ULg) Les canaux potassiques ATP-dépendants: nouvelles cibles potentielles pour le traitement de divers troubles métaboliques Florence, X.; De Tullio, Pascal ; Lebrun, P. et al Poster (2009, May) Detailed reference viewed: 8 (0 ULg) Conception, synthèse et évaluation biologique de dérivés coumariniques en tant qu’agents anti-cancéreux potentiels Hemmer, Marc ; Bambi Nyanguile, Sylvie-Mireille ; De Tullio, Pascal et al Poster (2009, May) Detailed reference viewed: 35 (19 ULg) Synthèse, étude de la métabolisation et évaluation pharmacologique du 3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxyde (BPDZ 73) et de ses métabolites Dintilhac, Gaëlle ; Florence, X.; Guillotin, F. et al Conference (2009, April 28) Detailed reference viewed: 14 (1 ULg) Les canaux potassiques ATP-dépendants : nouvelles cibles potentielles pour le traitement de divers troubles métaboliques Florence, X.; De Tullio, Pascal ; Lebrun, Ph. et al Conference (2009, February 03) Detailed reference viewed: 9 (0 ULg) Conception, synthèse et évaluation biologique de dérivés coumariniques en tant qu’agents anti-cancéreux potentiels Hemmer, M.; De Tullio, Pascal ; Konradowski, Erika et al Conference (2009, February 03) Detailed reference viewed: 10 (5 ULg) A short series of antidiabetic sulfonylureas exhibit multiple ligand PPARgamma-binding patterns Arrault, Alban; Rocchi, Stéphane; Picard, Frédéric et al in Biomedicine & Pharmacotherapy (2009), 63 Detailed reference viewed: 10 (1 ULg) New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as KATP channel openers: modulation of the 4-position Florence, Xavier ; Sebille, Sophie; De Tullio, Pascal et al in Bioorganic & Medicinal Chemistry (2009), 17 Detailed reference viewed: 17 (5 ULg) Coumarinic derivatives show anti-inflamatory effects on alveolor macrophages, but their anti-elastase activity is essential to reduce lung inflammation in vivo Bissonnette, E. Y.; Tremblay, G. M.; Turmel, V. et al in International Immunopharmacology (2009), 9 Detailed reference viewed: 25 (4 ULg) Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs ? Robert, S.; Ghiotto, J.; Pirotte, Bernard et al in Pharmacological Research (2009), 59 Detailed reference viewed: 10 (2 ULg) Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors Renard, Jean-François ; Arslan, Deniz ; Garbacki, Nancy et al in Journal of Medicinal Chemistry (2009), 52 Detailed reference viewed: 32 (6 ULg) Original cromakalim analogues as KATP channel openers Florence, Xavier ; De Tullio, Pascal ; Pirotte, Bernard et al in Metabolic and Functional Research on Diabetes (2009), 2 Detailed reference viewed: 25 (9 ULg) 6-Substituted 2-Oxo-2h-1-Benzopyran-3-Carboxylic Acid Derivatives in a New Approach of the Treatment of Cancer Cell Invasion and Metastasis Kempen, I.; Hemmer, Marc ; Counerotte, Stéphane et al in European Journal of Medicinal Chemistry (2008), 43(12), 2735-50 Novel 6-substituted 2-oxo-2H-1-benzopyran-3-carboxylic acid derivatives were synthesized and their potency in reducing the invasive behaviour of HT 1080 fibrosarcoma cells was evaluated. Structure ... [more ▼] Novel 6-substituted 2-oxo-2H-1-benzopyran-3-carboxylic acid derivatives were synthesized and their potency in reducing the invasive behaviour of HT 1080 fibrosarcoma cells was evaluated. Structure-activity relationships were deduced from biological results and will be used in further design of new active compounds. In particular, the acetoxymethyl substituent found at the 6-position of previously described active compounds can be replaced by an acetamidomethyl substituent without loss of potency; while the presence of an aryl ester function at the 3-position was preferred to a thioester or an amide function to induce marked biological activity. This work confirms the interest of aryl esters of 6-substituted coumarin-3-carboxylic acids as potential new anti-cancer agents. [less ▲] Detailed reference viewed: 85 (23 ULg) 1H NMR metabolomic approach of the laser-induced choroidal neovascularization in mice Lambert, Vincent ; Frederich, Michel ; Rousseau, Rousseau et al Poster (2008, August) Detailed reference viewed: 59 (30 ULg) Design, synthesis and pharmacological evaluation of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides acting as AMPA potentiators Francotte, Pierre ; De Tullio, Pascal ; Fraikin, Pierre et al Poster (2008, May 17) Detailed reference viewed: 3 (0 ULg) 1 2 3 4 5 6 7 8