References of "Pirotte, Bernard"
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See detailDevelopment of original pyridinic analogues of nimesulide as cycloxygenase inhibitors
Renard, Jean-François ULg; de Leval, Xavier; Pirotte, Bernard ULg

Conference (2007, October)

Detailed reference viewed: 7 (1 ULg)
Peer Reviewed
See detailDesign, synthesis, and pharmacological evaluation of cromakalim analogues as pancreatic β-cell-selective KATP channel openers
Florence, X.; De Tullio, Pascal ULg; Lebrun, Ph. et al

Conference (2007, October)

Detailed reference viewed: 40 (0 ULg)
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See detailThrombin activity profile: a rapid, reliable and relevant ex vivo screening test for the development of anticoagulant drugs
Robert, S.; Ghiotto, J.; Pirotte, Bernard ULg et al

Conference (2007, October)

Detailed reference viewed: 8 (0 ULg)
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See detailDesign, synthesis and anticancer activity of novel hydroxylated coumarin derivatives
Hemmer, Marc ULg; De Tullio, Pascal ULg; Bernard, Y. et al

Conference (2007, October)

Detailed reference viewed: 24 (0 ULg)
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See detailCromakalim analogues as pancreatic β-cell-selective KATP channel openers
Florence, X.; De Tullio, Pascal ULg; Lebrun, P. et al

Poster (2007, July)

Detailed reference viewed: 9 (1 ULg)
Peer Reviewed
See detailThrombin activity profile : a powerful ex vivo screening test for the development of anticoagulant drugs
Robert, S.; Ghiotto, J.; Pirotte, Bernard ULg et al

Poster (2007, July)

Detailed reference viewed: 8 (0 ULg)
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See detailConception et synthèse d’outils pharmacologiques originaux pour l’étude des récepteurs au thromboxane
Moray, A. L.; Dogne, J. M.; Neven, P. et al

Poster (2007, May)

Detailed reference viewed: 16 (1 ULg)
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See detailAChE Inhibitors and their Clinical Assessment
Francotte, Pierre ULg; De Tullio, Pascal ULg; Pirotte, Bernard ULg

in Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies (2007)

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See detailDesign, synthesis, and pharmacology of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors
Francotte, Pierre ULg; De Tullio, Pascal ULg; Goffin, Eric ULg et al

in Journal of Medicinal Chemistry (2007), 50(13), 3153-3157

A series of 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides have been synthesized and evaluated as potentiators of AMPA receptors. Attention was paid to the impact of the substituent introduced at the ... [more ▼]

A series of 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides have been synthesized and evaluated as potentiators of AMPA receptors. Attention was paid to the impact of the substituent introduced at the 7-position of the heterocycle. The biological evaluation was achieved by measuring the AMPA current in rat cortex mRNA-injected Xenopus oocytes. The most potent compound, 4-ethyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (12a) was found to be active in an object recognition test in rats demonstrating cognition enhancing effects in vivo after oral administration. [less ▲]

Detailed reference viewed: 57 (23 ULg)
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See detailCholinergic Transmission and Acetylcholine release enhancers
Francotte, Pierre ULg; De Tullio, Pascal ULg; Pirotte, Bernard ULg

in Protein Misfolding in neuro degenerative Diseases : Mechanisms and Therapeutic Strategies (2007)

Detailed reference viewed: 20 (5 ULg)