References of "Pirard, Catherine"
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See detailLevels of PCDDs, PCDFs and PCBs in International Fast Food Samples
Focant, Jean-François ULg; Pirard, Catherine; De Pauw, Edwin ULg

in Organohalogen Compounds (2003), 60-65

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See detailLevels and profiles of PCDDs, PCDFs and cPCBs in Belgian breast milk. Estimation of infant intake
Focant, Jean-François ULg; Pirard, Catherine; Thielen, Caroline ULg et al

in Chemosphere (2002), 48(8), 763-770

Congener-specific analyses of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and non-ortho (coplanar) polychlorinated biphenyls (cPCBs) were performed on 20 non-pooled ... [more ▼]

Congener-specific analyses of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and non-ortho (coplanar) polychlorinated biphenyls (cPCBs) were performed on 20 non-pooled breast milk samples collected in or close to an industrial area of Wallonia (Belgium). PCDD/F concentrations ranged between 16.0 and 52.1 pg TEQ/g fat, with a mean value of 29.4 pg TEQ/g fat. If coplanar PCBs (77, 126, 169) are included in TEQ calculations, levels ranged between 22.2 and 100.2 pg TEQ/g fat, with a mean value of 40.8 pg TEQ/g fat. It appears that 2,3,7,8-TCDD, 1,2,3,7,8-PeCDD, 2,3,4,7,8-PeCDF and PCB-126 account for more than 90% of the TEQ. Estimated PCDD/F dietary intake is 76 pg TEQ/kg body weight (bw)/day. This value is almost 20 times higher than the World Health Organization tolerable daily intake. A value of 103 pg TEQ/kg bw/day represents the intake of PCDDs, PCDFs and cPCBs (no mono-ortho PCBs included). (C) 2002 Published by Elsevier Science Ltd. [less ▲]

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See detailAn improved clean-up strategy for simultaneous analysis of polychlorinated dibenzo-p-dioxins (PCDD), polychlorinated dibenzofurans (PCDF), and polychlorinated biphenyls (PCB) in fatty food samples
Pirard, Catherine; Focant, Jean-François ULg; De Pauw, Edwin ULg

in Analytical and Bioanalytical Chemistry (2002), 372(2), 373-381

The study and extension of a simple automated clean-up method for polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF) to a broad range of polychlorinated biphenyls (PCB) is ... [more ▼]

The study and extension of a simple automated clean-up method for polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF) to a broad range of polychlorinated biphenyls (PCB) is described. The isolation of seven PCDD, ten PCDF, and three coplanar PCB (cPCB) is extended to eight monoortho substituted PCB and seven so-called "marker PCB" (Aroclor 1260) for fatty food samples. This enables quantification of 35 compounds - including all congeners with a WHO toxic equivalent factor (TEF)--in a single extraction and single purification step. The chromatographic behaviour of mono-ortho PCB and marker PCB on a variety of adsorbents, including basic alumina, has been studied. Partitioning of analytes through multi-column sequences is described and correlated with their structural and electronic properties, by use of molecular modelling calculations. The fractionation process available with the Power-Prep automated clean-up system enables rapid independent analysis of the different groups of compounds. Gas chromatography with high resolution mass spectrometry (GC-HRMS) is used for the PCDD/F and cPCB fraction and quadrupole ion-storage tandem in time mass spectrometry (GC-QISTMS) for analysis of the remaining PCB. A comparison study was performed on quality-control samples and real fatty food samples to evaluate the robustness of the new strategy compared with a reference method. On the basis of this simultaneous clean-up, a rapid simplified strategy for PCDD/F and selected PCB analysis determination is proposed for fatty food samples. [less ▲]

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See detailClean-up and determination of Organochlorine and Organobromine Compounds
Pirard, Catherine; Douny, Caroline ULg; Eppe, Gauthier ULg et al

in Organohalogen Compounds (2002)

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See detailAssesment of the situation, three years later, on 'the Belgian Dioxin Crisis'. Probable impact on the health of the Belgian population
Focant, Jean-François ULg; Pirard, Catherine; Douny, Caroline ULg et al

in Annales de Médecine Vétérinaire (2002), 146(6, DEC-JAN), 321-327

In January 1999, Belgium encounters an accidental contamination of the food chain, which was named "the Belgian Dioxin Crisis". The aim of the present review is to estimate the impact of this crisis on ... [more ▼]

In January 1999, Belgium encounters an accidental contamination of the food chain, which was named "the Belgian Dioxin Crisis". The aim of the present review is to estimate the impact of this crisis on public health. Currently, it does not really exist any exhaustive epidemiological study. Various scientific studies actually report somewhat conflicting results. As an example, concerning the population living in Wallonia, recorded dioxin levels are not higher than background levels reported for other industrialized countries, despite the 1999 "dioxin crisis". Conversely, based on levels measured in foodstuffs collected by the end of the crisis period, the dioxin body burden of potential consumers would have increased in the range of 40 to 75 %. The real impact of this crisis on consumers' health could thus only be estimated through well structured epidemiological campaigns. [less ▲]

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See detailFast Clean-up for Polychlorinated Dibenzo-P-Dioxins, Dibenzofurans and Coplanar Polychlorinated Biphenyls Analysis of High-Fat-Content Biological Samples
Focant, Jean-François ULg; Eppe, Gauthier ULg; Pirard, Catherine et al

in Journal of Chromatography. A (2001), 925(1-2), 207-21

A fast clean-up procedure for the low level analysis of polychlorinated dibenzo-p-dioxins. polychlorinated dibenzofurans and coplanar polychlorinated biphenyls in highly fatty biological matrices using ... [more ▼]

A fast clean-up procedure for the low level analysis of polychlorinated dibenzo-p-dioxins. polychlorinated dibenzofurans and coplanar polychlorinated biphenyls in highly fatty biological matrices using high capacity disposable multi-layer silica columns is presented. Results were compared with gel permeation chromatography for removal of lipids. Analytical criteria such as recovery rates, repeatability, reproducibility and robustness are evaluated through a broad range of biological matrices and reference materials analysis. The final proposed procedure for the complete analysis, including pressurized liquid extraction, Power-Prep system clean-up and GC-high-resolution MS analysis requires only 48 h, and allows the simultaneous preparation of up to 10 samples. [less ▲]

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