References of "Peulen, Olivier"
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See detailWHICH ARE THE ARGUMENTS ALLOWING TO PROPOSE THAT MILK POLYAMINES ARE PREVENTIVE AGENTS OF FOOD ALLERGY?
Dandrifosse, Guy ULg; Peulen, Olivier ULg; Kheffif, El et al

in European Commission Directorate General DG XII Sciences (2000)

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See detailPolycations: relationship between chemical structure and biological behaviour
Grandfils, Christian ULg; Peulen, Olivier ULg; Deloyer, P et al

in Biologically active amines in food (2000)

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See detailIntestinal maturation induced by spermine in young animals
Peulen, Olivier ULg; Deloyer, P; Grandfils, Christian ULg et al

in Livestock Production Science (2000), 66

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See detailAre there arguments suggesting that polyamines are preventive agents of food allergy?
Dandrifosse, Guy ULg; Peulen, Olivier ULg; El Khefif, Nor Eddine et al

in Morgan, D.; White, A.; Sanchez-Jimenez, F. (Eds.) et al COST 917 Biologically active amines in food. Volume IV (2000)

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See detailPolycations : relationship between chemical structure and biological behavior
Grandfils, Christian ULg; Peulen, Olivier ULg; Deloyer, Patricia et al

in Morgan, D.; White, A.; Sanchez-Jimenez, F. (Eds.) et al COST 917 Biologically active amines in food. Volume IV (2000)

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See detailLe point sur les polyamines
Dandrifosse, Guy ULg; Deloyer, P.; Grandfils, Christian ULg et al

in Revue Médicale de Liège (1999), 54(3), 175-83

Polyamines are ubiquitous substances. Their intracellular concentration is controlled quickly and rigorously by extremely sophisticated systems. It depends on metabolism and cellular permeability ... [more ▼]

Polyamines are ubiquitous substances. Their intracellular concentration is controlled quickly and rigorously by extremely sophisticated systems. It depends on metabolism and cellular permeability. Polyamines act as structural and functional elements in the cell (nucleic acid conformation, cytoskeleton, radioprotection, apoptosis, proliferation and differentiation of cells...). They also play a role in various diseases (origin of food allergy, cancers...). They present a great therapeutic interest (oncology, molecular transfer to cell nucleus, transfer across the blood-brain barrier, parasitosis, effects on NMDA and GABA receptors in the central nervous system...). [less ▲]

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See detailBiogenic amines in different types of Belgian beers: a first survey
Loret, S.; Bianchi, D.; Peulen, Olivier ULg et al

in Bardocz, S.; Koninckx, J.; Grillo, M. (Eds.) et al COST 917 Biogenically active amines in food. Volume III : Biologically active amines in food processing and amines produced by bacteria, and polyamines and tumour growth (1999)

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See detailAre there arguments allowing to propose that polyamines are preventive agents of food allergy
Dandrifosse, Guy ULg; Peulen, Olivier ULg; El Khefif, N et al

Conference (1998, November)

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See detailAmine polymers : relation : chemical structure
Grandfils, Christian ULg; Peulen, Olivier ULg; Deloyer, P et al

Conference (1998, November)

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See detailThe Relationship between Spermine Content of Human Milk During the First Postnatal Month and Allergy in Children
Peulen, Olivier ULg; Dewé, Walthère ULg; Dandrifosse, Guy ULg et al

in Public Health Nutrition (1998), 1(3), 181-4

DESIGN: Qualitative case study and mathematical model. SETTING: Belgium. OBJECTIVES: To evaluate the correlation between the polyamine mean concentration of the milk drunk during the first postnatal month ... [more ▼]

DESIGN: Qualitative case study and mathematical model. SETTING: Belgium. OBJECTIVES: To evaluate the correlation between the polyamine mean concentration of the milk drunk during the first postnatal month and the appearance of allergy in children who drank this milk. RESULTS: A model that describes the dependence of the allergy appearance with the spermine mean concentration of milk drunk during the first postnatal month was established. CONCLUSIONS: This model shows that 5.02 nmol ml(-1) of spermine is a critical value to prevent the appearance of allergy. [less ▲]

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See detailPolyamines as preventive agents of food allergy (CEE, COST 917)
Grandfils, Christian ULg; Peulen, Olivier ULg; Deloyer, P et al

Conference (1998, May)

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See detailComparison between the Natural Postnatal Maturation and the Spermine-Induced Maturation of the Rat Intestine
Peulen, Olivier ULg; Pirlet, Christine; Klimek, Monique ULg et al

in Archives of Physiology & Biochemistry (1998), 106(1), 46-55

In the suckling rats, orally provided spermine induced structural and biochemical changes in the intestine, which are characteristics of the postnatal maturation. This induced maturation was compared to ... [more ▼]

In the suckling rats, orally provided spermine induced structural and biochemical changes in the intestine, which are characteristics of the postnatal maturation. This induced maturation was compared to that occurring spontaneously. Eight mumol spermine were administered orally once a day, for one or three days, to suckling rats which were 11 days old at the beginning of the experiment. The animals were killed 0, 2, 4, 6, 8, 10 hours or 3 days after the first treatment. Control rats from the same litter were treated in the same way but received only the vehicle. In order to complete the study of the naturally occurring maturation, another group of rats was killed when they were 12, 13, 15, 16, 17, 18, 19, 20, 21 or 30 days old. Animal and intestine weights were measured. Disaccharidase specific activity, and protein, DNA and RNA contents were estimated in the small intestine. Histological and ultrastructural aspects of the intestinal mucosa were examined. For all these parameters, the maturation induced by spermine ingestion appeared close to that occurring naturally at weaning. Consequently, dietary spermine induces all the morphological and biochemical modifications characterizing the intestinal postnatal maturation in the suckling rat suggesting a role of the polyamines in the naturally occurring processes. [less ▲]

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See detailEffects of a long-term low-polyamine diet on biochemical parameters and polyamine content in different organs of the germ-free rat
Deloyer, Patricia; Peulen, Olivier ULg; Klimek, Monique ULg et al

in Bardocz, S.; White, A.; Hajos, G. (Eds.) COST 917 Biogenically active amines in food. Volume II : Metabolic effects of biologically active amines in food (1998)

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See detailDietary polyamines during lactation
Dandrifosse, Guy ULg; Deloyer, Patricia; El Khefif, Nor Eddine et al

in Bardocz, Suzan; White, Ann (Eds.) Polyamines in health and nutrition (1998)

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See detailRole of Interleukin-1 Beta, Interleukin-6, and Tnf-Alpha in Intestinal Maturation Induced by Dietary Spermine in Rats
Kaouass, M.; Deloyer, Patricia; Gouders, Isabelle et al

in Endocrine (1997), 6(2), 187-94

In the present investigation, the authors aimed to evaluate the role of cytokines in intestinal postnatal maturation induced by dietary polyamines. Neonatal rats were administered either saline (8 mumol ... [more ▼]

In the present investigation, the authors aimed to evaluate the role of cytokines in intestinal postnatal maturation induced by dietary polyamines. Neonatal rats were administered either saline (8 mumol) orally. Spermine increased interleukin-1 beta (IL-1 beta), IL-6, and TNF-alpha plasma concentration. The maximum concentrations of IL-1 beta, IL-6, and TNF-alpha were, respectively, observed at 4, 4, and 8 h posttreatment. Intraperitoneal (i.p.) injection of IL-1 beta increased the specific activity of sucrase in whole small intestine, whereas the specific activities of maltase and lactase were significantly enhanced only in the jejunum. IL-6 elicited sucrase and increased maltase specific activity in the whole small intestine, but lactase specific activity was not affected. TNF-alpha had no effect on sucrase and maltase specific activity, but a slight augmentation of lactase specific activity was detected in the jejunum. Spermine and spermidine content in the intestine was increased by i.p. injection of IL-1 beta and IL-6. Corticosterone secretion was elevated by single i.p. injection of IL-1 beta, IL-6, or TNF-alpha. These findings suggest that spermine could induce postnatal intestinal development and corticosterone secretion through a cytokine-dependent mechanism. [less ▲]

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