Efficacy of intrasinusal administration of bifonazole cream alone or in combination with enilconazole irrigation in canine sino-nasal aspergillosis: 17 cases.

in Canadian Veterinary Journal = Revue Vétérinaire Canadienne (2010), 51(2)

Correlation of palpated pulse and invasive arterial blood pressure in dogs.

in Proceedings of the 9th EVECCS Annual meeting (2010)

Emesis in dogs: a review

in Journal of Small Animal Practice (2010), 51

Cytokine expression by Aspergillus fumigatus stimulated peripheral blood mononuclear cells from dogs with sino-nasal aspergillosis.

in Proceedings of the 20th Annual Congress of the ECVIM-CA (2010)

Comparison of the value of fungal culture and galactomannan detection in nasal secretions obtained by three non-invasive sampling methods in the diagnosis of canine sinonasal aspergillosis

in Proceedings of the 19th ECVIM-CA Congress (2009, September)

Comparison of the value of measurement of serum galactomannan and Aspergillus-specific antibodies in the diagnosis of canine sino-nasal aspergillosis.

in Veterinary Microbiology (2009), 133(4), 358-65

Serology is currently used for the diagnosis of canine sino-nasal aspergillosis (SNA). However, the accuracy of serological testing using commercially available, standardized purified antigen preparations ... [more ▼]

Serology is currently used for the diagnosis of canine sino-nasal aspergillosis (SNA). However, the accuracy of serological testing using commercially available, standardized purified antigen preparations of Aspergillus (CAPurAspAg) has only been poorly documented. The aim of the present study was to assess the diagnostic value of an agar-gel double immunodiffusion (AGDD) test and an anti-Aspergillus IgG ELISA, using CAPurAspAg and the commercially available Platelia test for the detection of serum galactomannan. Sera from 17 dogs with SNA, 18 dogs with a nasal tumour (NT), 11 dogs with lymphoplasmacytic rhinitis (LPR) and 33 control dogs were tested with the 3 methods. AGDD result was positive in 76.5% of dogs with SNA, whereas all sera from dogs with non-fungal nasal disease and control dogs were negative. A positive IgG ELISA result was obtained in 88% of dogs with SNA and in 18% of dogs with LPR. All patients with NT and control dogs had a negative IgG ELISA result. The Platelia test was positive in 24% of dogs with SNA, 11% of dogs with NT, 9% of dogs with LPR and 24% of control dogs. The results of this study suggest that (1) the detection of serum Aspergillus-specific antibodies with AGDD or ELISA, using CAPurAspAg, provides excellent specificity and good sensitivity, (2) the specificity is higher for AGDD (100%) than for ELISA (96.8%) while sensitivity is higher for ELISA (88.2%) than for AGDD (76.5%) and (3) serum galactomannan quantification with the Plateliat test is unreliable for the diagnosis of canine SNA. [less ▲]

Characterisation of the acute and reversible airway inflammation induced by cadmium chloride inhalation in healthy dogs and evaluation of the effects of salbutamol and prednisolone.

in Veterinary Journal (2009), 179(3), 443-450

The aims of this study were firstly to characterise a model of subclinical and reversible bronchial inflammation induced by cadmium chloride inhalation in healthy dogs and then to examine the effect of ... [more ▼]

The aims of this study were firstly to characterise a model of subclinical and reversible bronchial inflammation induced by cadmium chloride inhalation in healthy dogs and then to examine the effect of prednisolone or salbutamol treatment on the resulting bronchitis. The model characterisation and the effects of treatment were studied using clinical symptoms, haematology, thoracic radiography, bronchoscopy and bronchoalveolar lavage, barometric whole-body plethysmography and histamine broncho-provocation tests. In addition, the activity of matrix metalloproteinases (MMP)-2 and -9 were determined in serum and bronchoalveolar lavage fluid (BALF). Cadmium inhalation induced: (1) a transient bronchial inflammation, dominated by neutrophils; (2) a neutrophilia of the blood that persisted for up to 4weeks; (3) a transient increased bronchial reactivity, and (4) a significant increase in MMP-9 activity in the BALF. Prednisolone treatment reduced the influx of inflammatory cells into the BALF, but not significantly, had no effect on pulmonary function, and did not reduce of airway hypersensitivity. Salbutamol had almost no effect on any of the parameters investigated. [less ▲]

Concentration of allergen-specific IgE in serum and bronchoalveolar lavage fluid in dogs with eosinophilic bronchopneumopathy and dogs with chronic bronchitis.

in Proceedings of the 19th Annual Congress of the ECVIM-CA (2009)

Clinical efficacy of intrasinusal administration of bifonazole cream through perendoscopically placed catheters alone or in combination with enilconazole irrigation in canine sinonasal aspergillosis.

in Proceedings of the 18th ECVIM-CA Congress (2008, September)

Familial glomerulopathy in seven French Mastiff dogs.

in Proceedings of the 18th Annual Congress of the ECVIM-CA (2008)