References of "Peeters, Dominique"
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See detailLocal immune response in canine sino-nasal aspergillosis
Peeters, Dominique ULg

in Proceedings of the 16th Congress of the International Society for Human and Animal Mycology (2006, June)

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See detailLa peau : miroir de la santé
Peeters, Dominique ULg; Remy, Isabelle

in Proceedings of "Congrès SAVAB" (2006, February)

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See detailLes maladies transmises par les tiques chez le chien en Belgique
Peeters, Dominique ULg

in Proceedings of "Congrès SAVAB" (2006, February)

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See detailDiagnosis of canine sino-nasal aspergillosis: is quantification of Aspergillus DNA a useful technique?
Peeters, Dominique ULg; Peters, I. R.; Helps et al

in Proceedings of the 24th VCRS meeting (2006)

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See detailCytokine and chemokine expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinosinusitis.
Peeters, Dominique ULg; Peters, I. R.; Helps, C. et al

in Proceedings of the 16th Annual Congress of the ECVIM-CA (2006)

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See detailDistribution of leucocyte subsets in the canine pharyngeal tonsil
Billen, Frédéric ULg; Peeters, Dominique ULg; Dehard, Sandrine ULg et al

in Journal of Comparative Pathology (2006), 135(2-3, Aug-Oct), 63-73

This report describes the distribution and nature of lymphoid tissue in the nasopharyngeal mucosa of six puppies (mean age +/- SD, 0.3 +/- 0.25 years) and eight adult dogs (mean age +/- SD, 8.8 +/- 2.67 ... [more ▼]

This report describes the distribution and nature of lymphoid tissue in the nasopharyngeal mucosa of six puppies (mean age +/- SD, 0.3 +/- 0.25 years) and eight adult dogs (mean age +/- SD, 8.8 +/- 2.67 years) without respiratory disease. A non-encapsulated area of organized mucosa-associated lymphoid tissue was observed in the caudal part of the posterior wall of the nasopharynx, distal to the openings of the auditory tubes. This structure was consistent with the pharyngeal tonsil and was microscopically more extensive in puppies than in adult dogs. Histochemistry and immunohistochemistry were used to characterize and enumerate the leucocyte subsets in this part of the nasopharynx. Mast cells were found immediately beneath the respiratory epithelium but were also scattered in the glandular and muscular tissue. IgA(+) plasma cells outnumbered IgG(+) and IgM(+) plasma cells, especially in the glandular tissue. All classes of plasma cells were present in significantly greater numbers in adults than in puppies. MHC class II+ cells were mainly observed in areas containing diffuse and follicular aggregates of lymphoid cells. Both MHC class II+ cells and CD1c(+) cells with a dendritic morphology were predominantly found immediately beneath or within the epithelium, and cells expressing these markers were more abundant in puppies than in adult dogs. The anti-L1 marker labelled low numbers of cells with a neutrophilic morphology, which were significantly more abundant in puppies than in adult dogs. The majority of lymphoid cells were CD3(+) T lymphocytes and these were particularly abundant in areas containing aggregates of lymphold cells; CD4(+), CD8(+) and TCR alpha beta(+) cells had the same distribution as the CD3(+) cells. CD4(+) cells were more numerous than CD8(+) cells. The quantitative and qualitative data obtained will enable comparisons to be made with similar studies in dogs suffering from nasopharyngeal diseases, or when the local immune system needs to be investigated. (c) 2006 Elsevier Ltd. All rights reserved. [less ▲]

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See detailQuantification of mRNA encoding cytokines and chemokines in nasal biopsies from dogs with sino-nasal aspergillosis
Peeters, Dominique ULg; Peters, I. R.; Clercx, Cécile ULg et al

in Veterinary Microbiology (2006), 114(3-4), 318-326

Canine sino-nasal aspergillosis is usually caused by Aspergillus fumigatus and is similar to human chronic erosive non-invasive fungal sinusitis. The pathogenesis of the disease is poorly understood. We ... [more ▼]

Canine sino-nasal aspergillosis is usually caused by Aspergillus fumigatus and is similar to human chronic erosive non-invasive fungal sinusitis. The pathogenesis of the disease is poorly understood. We investigated the nature of the local immune response mounted in canine sino-nasal aspergillosis. Quantitative RT-PCR was carried out on RNA isolated from nasal biopsies from diseased and control dogs, using specific assays designed to amplify mRNA encoding a panel of cytokines and chemokines. Canine sino-nasal aspergillosis was associated with significantly increased expression of mRNA encoding MCP-1, -2, -3 and -4, IL-8, IL-10, EL-18 and TNF-alpha relative to controls (P < 0.01) but there was no difference between groups with respect to IL-4, IL-5, IL-6, IL-12, TGF-beta, and eotaxin-2 and -3. The up-regulation of proinflammatory cytokines and chemokines related to the influx of phagocytic cells might account for the localisation of this infection to the upper respiratory tract. The up-regulation of the expression of the immunomodulatory cytokine IL-10 in nasal tissue from affected dogs might be important in limiting the extent of local tissue destruction, but might also account for the fact that infected dogs are generally unable to clear this infection spontaneously. (c) 2005 Elsevier B.V. All rights reserved. [less ▲]

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See detailEffect of sampling method and culture conditions on the result of fungal culture in the diagnosis of canine sino-nasal aspergillosis.
Legarrérès, A.; Clercx, Cécile ULg; Mignon, Bernard ULg et al

in Proceedings of the 24th VCRS meeting (2006)

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See detailReal-time RT-PCR quantification of mRNA encoding cytokines, CC chemokines and CCR3 in bronchial biopsies from dogs with eosinophilic bronchopneurnopathy
Peeters, Dominique ULg; Peters, I. R.; Clercx, Cécile ULg et al

in Veterinary Immunology and Immunopathology (2006), 110(1-2), 65-77

Idiopathic canine eosinophilic bronchopneumopathy (EBP) is a disease characterized by eosinophilic infiltration of the pulmonary interstitium and bronchial mucosa, a cause for which has not yet been ... [more ▼]

Idiopathic canine eosinophilic bronchopneumopathy (EBP) is a disease characterized by eosinophilic infiltration of the pulmonary interstitium and bronchial mucosa, a cause for which has not yet been discovered. A recent study, examining the relative proportion of various lymphocyte cell subsets within bronchoalveolar lavage fluid from dogs with EBP, has shown a selective increase in CD4(+) T-cells and a selective decrease in CD8(+) T-cells, suggesting that a similar Th2 immune response might occur in EBP. The aim of the present study was to determine the profile of cytokine, chemokine and CC chemokine receptor 3 (CCR3) messenger RNA (mRNA) expression in bronchial tissue from dogs with EBP. Real-time RT-PCR assays were used for the quantification of mRNA encoding for a panel of cytokines, CC chemokines and CCR3 in perendoscopic bronchial biopsies from eight dogs with EBP and seven age-matched control dogs. Messenger RNA transcribed from the housekeeping gene glyceraldehyde-3 -phosphate dehydrogenase was used for normalisation of the threshold cycle in order to determine the relative copy numbers of the transcripts. No significant difference in the expression of any cytokine, MCP-1, -2, -4 and CCR3 was found between control and EBP dogs. The expression of transcript for MCP-3, eotaxin-2 and -3 was significantly greater in bronchial biopsies from dogs with EBP than in samples from control dogs while there was significantly less mRNA encoding RANTES in the mucosa of dogs with EBP. In conclusion, the cytokine mRNA expression profile in perendoscopic bronchial biopsies is similar in dogs with EBP and dogs without respiratory disease. Further studies on the quantification of mRNA encoding cytokines in isolated T lymphocytes from bronchoalveolar lavage fluid or bronchial biopsies are needed before any conclusion on the cytokine profile in canine EBP can be drawn. Eotaxin-2, -3 and MCP-3 appear to be implicated in the pathogenesis of the disease. (c) 2005 Elsevier B.V. All rights reserved. [less ▲]

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See detailSuspected drug-induced destructive cholangitis in a young dog.
Gabriel, Alexandra; van den Ingh, Ted; Clercx, Cécile ULg et al

in Journal of Small Animal Practice (2006), 47(6)

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See detailLaryngeal paralysis-polyneuropathy complex in young related Pyrenean Mountain dogs.
Gabriel, Alexandra; Poncelet, Luc; Van Ham, Luc et al

in Journal of Small Animal Practice (2006), 47(3)

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See detailHistochemical and immunohistochemical characterization of canine nasopharyngeal lymphoid tissue
Billen, Frédéric ULg; Peeters, Dominique ULg; Dehard, Sandrine ULg et al

in 15th ESVIM Meeting - Glasgow - Ecosse - Septembre 2005 (2005, September)

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See detailComparison of bronchoalveolar lavage cytospins ans smears in small animals
Dehard, Sandrine ULg; Bernaerts, Frederique ULg; Peeters, Dominique ULg et al

in 15th ESVIM Meeting - Glasgow - UK - 2005 (2005, September)

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See detailHistochemical and immunohistochemical characterisation of canine nasopharyngeal lymphoid tissue
Billen, Frédéric ULg; Peeters, Dominique ULg; Dehard, Sandrine ULg et al

in Proceedings of the 15th ECVIM-CA Congress (1-3/09/2005), Glasgow, Scotland (2005, September)

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See detailQuantification of mRNA encoding cytokines, chemokines and CCR3 in bronchial biopsies from dogs with eosinophilic bronchopneumopathy.
Peeters, Dominique ULg; Peters, I. R.; Clercx, Cécile ULg et al

in Proceedings of the 15th Annual Congress of the ECVIM-CA (2005)

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See detailQuantification of mRNA encoding cytokines and chemokines in nasal biopsies from dogs with sino-nasal aspergillosis.
Peeters, Dominique ULg; Peters, I. R.; Clercx, Cécile ULg et al

in Proceedings of the 15th Annual Congress of the ECVIM-CA (2005)

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See detailInhaled and systemic corticosteroids decrease Matrix Metalloproteinase-9 in bronchoalveolar lavage fluid of asthmatic cats
Leemans, Jérôme ULg; Kirschvink, Nathalie; Delvaux, François ULg et al

in In Proceedings:15th Congress European College of Veterinary Internal Medicine – companion animals (2005)

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See detailEffect of oral and inhaled corticosteroids on bronchial reactivity and airway inflammation in a feline model of asthma
Kirschvink, Nathalie; Leemans, Jérôme ULg; Delvaux, François ULg et al

in In proceedings: 15th Congress European College of Veterinary Internal Medicine – companion animals (2005)

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