References of "Pasleau, Françoise"
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See detailThe CD-Rom's in the Medical Library : an 8 year Follow-up Evaluation.
Pasleau, Françoise ULiege; Quinaux, N.; Severyns, A.-M. et al

Poster (1996, September)

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See detailIdentification du site de fixation d'un facteur de transcription contribuant à la surexpression du gène c-erbB2 dans les cellules tumorales BT-474.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Hodzic, Didier et al

Conference (1996, February 14)

Detailed reference viewed: 25 (3 ULiège)
See detailIdentification of the cis element recognized by a transcription factor specific to the tumor BT-474 mammary cells.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Hodzic, Didier et al

Conference (1996, February 03)

Detailed reference viewed: 7 (0 ULiège)
Peer Reviewed
See detailSpecific transcription factors control the c-erbB2 gene expression in the mammary tumor BT-474 cells.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Garsoux, G. et al

Conference (1995, December)

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See detailSpecific transcription factors regulate the c-erbB2 expression in the tumor BT-474 mammary cells.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Gol-Winkler, Rose

Conference (1995, March 24)

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See detailDes facteurs de transcription spécifiques contrôlent l'expression du gène c-erbB2 dans les cellules épithéliales mammaires tumorales BT-474.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Winkler-Gol, Rose

Conference (1995, February 16)

Detailed reference viewed: 14 (0 ULiège)
See detailSpecific transcription factors of the tumor BT-474 mammary cells.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Winkler-Gol, Rose

Conference (1995, January 21)

Detailed reference viewed: 19 (0 ULiège)
See detailSpecific transcription factors of the tumor BT-474 mammary cells regulate the c-erbB2 gene expression.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Gol-Winkler, Rose

Conference (1994, December 22)

Detailed reference viewed: 12 (0 ULiège)
Peer Reviewed
See detailThe 6 kb c-erbB2 promoter contains positive and negative regulatory elements functional in human mammary cell lines.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Dijkmans, Huguette et al

Conference (1994, September)

Detailed reference viewed: 20 (3 ULiège)
Peer Reviewed
See detailThe expression of ps2 and c-myc mRNAs are powerful predictors of relapse and death in breast cancers.
Gol-Winkler, R.; Hardy, L.; Autier, P. et al

Conference (1994, September)

Detailed reference viewed: 27 (2 ULiège)
Full Text
Peer Reviewed
See detailThe 6-Kilobase C-Erbb2 Promoter Contains Positive and Negative Regulatory Elements Functional in Human Mammary Cell Lines
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Dijkmans, Huguette et al

in Cancer Research (1994), 54(15), 4193-9

A 6-kilobase fragment extending at the 5'-end of the c-erbB2 protooncogene was isolated from a normal human lymphocyte genomic DNA library. The full-length fragment and five subfragments with identical 3 ... [more ▼]

A 6-kilobase fragment extending at the 5'-end of the c-erbB2 protooncogene was isolated from a normal human lymphocyte genomic DNA library. The full-length fragment and five subfragments with identical 3'-ends were obtained by progressive unidirectional deletion from the 5'-end and were cloned in front of the luciferase reporter gene. The hybrid genes were analyzed for transcriptional activity in human mammary cell lines synthesizing low (HBL-100 and T-47D), moderate (MDA-MB-453), or high (BT-474) amounts of the c-erbB2 mRNA and were also analyzed in HeLa cells. Gene-specific expression was observed, indicating the presence of multiple cis-acting sequences in the c-erbB2 promoter. A major negative element is located in the -2- to -4-kilobase region. It is flanked on both sides by positive elements that display enhanced transcriptional activity in the BT-474 tumor cells only. While predominant in the low-expressing cells, the effect of the repressor appears to be overcome by the distal transactivator in the high-expressing BT-474 cells, resulting in a 15 to 50 times increase in luciferase activity relative to the HBL-100 and T-47D cells, respectively. Cell-specific expression relies on the trans-acting factors present in the different cell lines. The formation of cell-specific protein-DNA complexes was demonstrated by gel retardation assay. [less ▲]

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See detailRégulation de l'expression de l'oncogène c-erbB2 dans les cancers mammaires humains.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Dijkmans, Huguette et al

Conference (1994, May 06)

Detailed reference viewed: 63 (1 ULiège)
See detailThe c-erbB2 upstream regulatory region contains positive and negative cis-acting elements differentially active in human mammary tumor cell lines.
Grooteclaes, Madeleine; Pasleau, Françoise ULiege; Berzi, Paulette et al

Conference (1994, January 29)

Detailed reference viewed: 12 (2 ULiège)
See detailBreast-specific expression of erbB2-LUC reporter genes.
Pasleau, Françoise ULiege; Grooteclaes, Madeleine; Berzi, Paulette et al

Conference (1993, November 11)

Detailed reference viewed: 13 (1 ULiège)
See detailMolecular alterations in breast cancers : deregulation of c-erbB2 gene expression.
Gol-Winkler, Rose; Pasleau, Françoise ULiege; Grooteclaes, Madeleine et al

Conference (1993, September)

Detailed reference viewed: 19 (0 ULiège)