References of "PIERARD, Luc"
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See detailLeft atrial function and remodelling in aortic stenosis.
O'Connor, K.; Magne, Julien ULg; Rosca, M. et al

in European Journal of Echocardiography (2011), 12(4), 299-305

AIMS: The present study sought to determine the relationship between left atrial (LA) volume (structural changes) and LA function as assessed by strain rate imaging in patients with aortic stenosis (AS ... [more ▼]

AIMS: The present study sought to determine the relationship between left atrial (LA) volume (structural changes) and LA function as assessed by strain rate imaging in patients with aortic stenosis (AS). <br />METHODS AND RESULTS: The study consisted of a total of 64 consecutive patients with severe AS (<1 cm²) and 20 healthy control subjects. The phasic LA volumes and function (tissue Doppler-derived strain) were assessed in all patients. As compared with healthy controls, all strain-derived parameters of LA function were reduced in patients with AS. Conversely, only indexed LA passive volume (increased) (7.6 ± 3.8 vs. 10.5 ± 5.1 ml/m², P= 0.02) and LA active fraction (decreased) (43 ± 6.7 vs. 31 ± 13.3%, P< 0.001) (volume-based parameters) were significantly different between AS and controls. In AS, LA volume-derived function parameters were poorly correlated with LA strain parameters. In fact, by multivariable analysis, no LA phasic strain parameters emerged as independently associated with LA phasic volume parameters. <br />CONCLUSIONS: In AS, changes in LA function did not parallel changes in LA size. Furthermore, the increase in LA volume does not necessarily reflect the presence of intrinsic LA dysfunction [less ▲]

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See detailImpact of aortic stenosis on longitudinal myocardial deformation during exercise.
Donal, E.; Thebault, C.; O'Connor, K. et al

in European Journal of Echocardiography (2011)

In aortic stenosis (AS), left ventricular (LV) adaptation to exercise has poorly been examined. Changes in LV ejection fraction may lack accuracy in identifying the presence of intrinsic myocardial ... [more ▼]

In aortic stenosis (AS), left ventricular (LV) adaptation to exercise has poorly been examined. Changes in LV ejection fraction may lack accuracy in identifying the presence of intrinsic myocardial impairment. AIMS: We sought to determine the impact of aortic stenosis (AS) on left ventricular (LV) longitudinal function at exercise in a series of asymptomatic patients with AS and preserved LV ejection fraction. METHODS AND RESULTS: Long-axis function was assessed at rest and at exercise by using 2D speckle tracking of myocardial deformation in 207 AS patients (aortic valve area 0.87 ± 0.19 cm²) and 43 aged-matched control subjects. When compared with control subjects, patients with AS have reduced longitudinal myocardial function at rest (-20.2 ± 2.7 vs. -15.4 ± 4.0%) and at peak exercise (-25.0 ± 3.7 vs. -16.5 ± 4.9%) (P < 0.0001 for both). Exercise changes in global longitudinal strain were correlated with changes in LV ejection in controls but not in patients with AS. Changes in LV global longitudinal strain during test were lower in AS patients with an abnormal response to exercise (-0.5 ± 2.7 vs. -1.5 ± 2.8%, P = 0.001). In multivariate analysis, a lower global longitudinal strain at rest (P = 0.04), a higher increase in mean trans-valvular pressure gradient (P < 0.001) at exercise, and smaller exercise-induced changes in global longitudinal strain (P < 0.001) were associated with an abnormal exercise test. CONCLUSION: In AS, subnormal LV function can be reliably identified by 2D strain imaging at rest and during a sub-maximal exercise. That sensitive measure of LV systolic function is depressed in AS and even more in patients having the most severe AS. [less ▲]

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See detailLa Vignette diagnostique de l'étudiant: Critères électrocardiographiques d’une tachycardie ventriculaire
GARWEG, Christophe ULg; BOLOGNE, Jean-Christophe ULg; MELON, Pierre ULg et al

in Revue Médicale de Liège (2011)

Recording of a regular wide QRS tachycardia is often source of panic and anxiety for the young clinician who has to make the differential diagnosis between ventricular tachycardia and supraventricular ... [more ▼]

Recording of a regular wide QRS tachycardia is often source of panic and anxiety for the young clinician who has to make the differential diagnosis between ventricular tachycardia and supraventricular tachycardia with aberration associated with fundamentally different vital prognosis. Most of the time, a rigorous approach and a systematic analysis of the electrocardiogram associated with clinical examination allow to obtain the correct diagnosis. [less ▲]

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See detailUse of contrast echocardiography in intensive care and at the emergency room.
Cosyns, Bernard; Roossens, Bram; Hernot, Sophie et al

in Current Cardiology Reviews (2011), 7(3), 157-62

Bedside echocardiography in emergency room (ER) or in intensive care unit (ICU) is an important tool for managing critically ill patients, to obtain a timely accurate diagnosis and to immediately stratify ... [more ▼]

Bedside echocardiography in emergency room (ER) or in intensive care unit (ICU) is an important tool for managing critically ill patients, to obtain a timely accurate diagnosis and to immediately stratify the risk to the patient's life. It may also render invasive monitoring unnecessary. In these patients, contrast echocardiography may improve quality of imaging and also may provide additional information, especially regarding myocardial perfusion in those with suspected coronary artery disease. This article focuses on the principle of contrast echocardiography and the clinical information that can be obtained according to the most frequent presentations in ER and ICU. [less ▲]

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See detailComment j'explore... Une arythmie ventriculaire chez le sportif
Tombeux, C.; MELON, Pierre ULg; Close, P. et al

in Revue Médicale de Liège (2011), 66(1), 30-33

How I explore : ventricular arrhythmhmias in athletes <br />SUMMARY : Documented ventricular tachyarrhythmias or related symptoms need meticulous cardiac investigations. The mechanism of ventricular ... [more ▼]

How I explore : ventricular arrhythmhmias in athletes <br />SUMMARY : Documented ventricular tachyarrhythmias or related symptoms need meticulous cardiac investigations. The mechanism of ventricular arrhythmia must be defined. The prognosis is related to underlying cardiac electrical or structural disorders. In the absence of cardiovascular abnormalities, the prognosis is good. No disqualification to competitive activity is required in most cases. Assessment of the risk of sudden death remains a continuing challenge in athletes. This article reviews the diagnostic and therapeutic approaches of ventricular arrhythmias encountered in trained athletes. [less ▲]

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See detailClinical significance of active myeloperoxidase in carotid atherosclerotic plaques
GACH, Olivier ULg; Magne, Julien ULg; Franck, Thierry ULg et al

in International Journal of Cardiology (2011), 152(1), 149-151

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See detailImpact of aortic stiffness on left ventricular function and B-type natriuretic peptide release in severe aortic stenosis.
Rosca, M.; Magne, Julien ULg; Calin, A. et al

in European Journal of Echocardiography (2011), 12(11), 850-856

Aims: In aortic stenosis (AS), both reduced systemic arterial compliance and increased valvular load have been shown to contribute to impaired left ventricular (LV) function. However, the relationship ... [more ▼]

Aims: In aortic stenosis (AS), both reduced systemic arterial compliance and increased valvular load have been shown to contribute to impaired left ventricular (LV) function. However, the relationship between LV function and aortic stiffness has not yet been investigated. We aimed to assess the relationship between aortic stiffness and LV global longitudinal strain (GLS), LV filling pressures (E/E′) and B-type natriuretic peptide (BNP) in AS. <br />Methods and results : A comprehensive echocardiogram was performed in 48 consecutive patients with severe AS (,0.6 cm2/m2) and preserved LV ejection fraction (≥50%). Aortic stiffness index (beta) was calculated based on aortic diameters measured by echocardiography and blood pressure. Systemic arterial compliance (SAC) and valvulo-arterial impedance (Zva) <br />were also determined. Aortic beta index was significantly correlated with Zva (r ¼ 0.30, P ¼ 0.03) and SAC (r ¼ 20.29, P ¼ 0.04). GLS (r ¼ 0.45, P ¼ 0.001), E/E′ (r ¼ 0.48, P ¼ 0.001) and BNP levels (r ¼ 0.45, P ¼ 0.001) were significantly related to aortic beta index. No significant correlation was found between GLS or E/E′ and SAC or Zva. In multivariate regression analysis, aortic beta index remained correlated with GLS, E/E′, and BNP levels. <br />Conclusions : In patients with severe AS and preserved LV ejection fraction, independently of the valvular load, an increase in aortic rigidity, as assessed by aortic beta index, is independently correlated with reduced LV longitudinal function, increased LV filling pressures, and BNP levels. [less ▲]

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See detailDeterminant and Impact on Outcome of Exercise Pulmonary Hypertension in Asymptomatic Severe Aortic Stenosis.
Magne, Julien ULg; Donal, E; O'Connor, K et al

Conference (2011)

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See detailBrain natriuretic peptide in asymptomatic degenerative mitral regurgitation: determinants and impact on outcome.
Van de Heyning, C; Magne, Julien ULg; Mahjoub, H et al

Conference (2011)

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See detailValvular heart disease: mitral valve disease
LANCELLOTTI, Patrizio ULg; Magne, Julien ULg; O'Connor, K et al

in The EAE textbook of echocardiography (2011)

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See detailPrediction of exercise pulmonary hypertension in asymptomatic degenerative mitral regurgitation
Magne, Julien ULg; Lancellotti, Patrizio ULg; O'Connor, K. et al

in Journal of the American Society of Echocardiography (2011), 24(9), 1004-1012

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See detailAssessment and management of aortic stenosis [Evaluation et traitement de la sténose aortique]
Pirlet, C.; Magne, Julien ULg; Lancellotti, Patrizio ULg et al

in Revue Medicale Suisse (2011), 7(306), 1606-1611

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See detailStress testing in valvular heart disease: Clinical benefit of echocardiographic imaging
Roşca, M.; Lancellotti, Patrizio ULg; Magne, Julien ULg et al

in Expert Review of Cardiovascular Therapy (2011), 9(1), 81-92

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See detailInfluence of thermoelectric coupling on ectopic beats generated by mechano-electric feedback (MEF) in a one-dimensional cardiac fiber model
Collet, Arnaud ULg; Desaive, Thomas ULg; Pierard, Luc ULg et al

in 9th Belgian Day on Biomedical Engineering, Friday November 26th 2010 in the Academy Palace, Hertogstraat 1, 1000 Brussels (2010, November 26)

The influence of thermal processes on electrophysiology has clearly been underlined by Bini et al., using a FitzHugh--Nagumo-type (FHN-type) model. When the temperature is raised, the action potential ... [more ▼]

The influence of thermal processes on electrophysiology has clearly been underlined by Bini et al., using a FitzHugh--Nagumo-type (FHN-type) model. When the temperature is raised, the action potential duration (APD) has been shown to shorten, while the action potential (AP) amplitude decreases, and the conduction velocity increases. In this research, we investigate the effects of thermoelectric coupling on mechano-electric feedback (MEF), and more specifically, on ectopic beats generated by MEF. To investigate these effects, thermoelectric coupling is introduced in a one-dimensional electromechanical model of a cardiac fiber, which considers excitation-contraction coupling (ECC), as well as MEF. [less ▲]

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See detailInfluence of thermoelectric coupling on ectopic beats generated by mechano-electric feedback (MEF) in a one-dimensional cardiac fiber model
Collet, Arnaud ULg; Desaive, Thomas ULg; Pierard, Luc ULg et al

Poster (2010, November 26)

The influence of thermal processes on electrophysiology has clearly been underlined by Bini et al., using a FitzHugh--Nagumo-type (FHN-type) model. When the temperature is raised, the action potential ... [more ▼]

The influence of thermal processes on electrophysiology has clearly been underlined by Bini et al., using a FitzHugh--Nagumo-type (FHN-type) model. When the temperature is raised, the action potential duration (APD) has been shown to shorten, while the action potential (AP) amplitude decreases, and the conduction velocity increases. In this research, we investigate the effects of thermoelectric coupling on mechano-electric feedback (MEF), and more specifically, on ectopic beats generated by MEF. To investigate these effects, thermoelectric coupling is introduced in a one-dimensional electromechanical model of a cardiac fiber, which considers excitation-contraction coupling (ECC), as well as MEF. [less ▲]

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