References of "PIERARD, Luc"
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See detailPrognostic importance of exercise brain natriuretic peptide in asymptomatic degenerative mitral regurgitation
Magne, Julien ULg; Mahjoub, H.; Pibarot, P. et al

in European Journal of Heart Failure (2012), 14(11), 1293-1302

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See detailThe importance of exercise echocardiography for clinical decision making in primary mitral regurgitation
Van De Heyning, C. M.; Magne, Julien ULg; Lancellotti, Patrizio ULg et al

in Journal of Cardiovascular Medicine (Hagerstown, Md.) (2012), 13(4), 260-265

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See detailThe role of multi-imaging modality in primary mitral regurgitation
Van de Heyning, C.; Magne, Julien ULg; Vrints, C. et al

in European Journal of Echocardiography (2012), 13(2), 139-151

Primary mitral regurgitation (MR) is the first cause of valvular regurgitation in Western countries. Echocardiography is the cornerstone for diagnosing MR and more specifically for establishing its ... [more ▼]

Primary mitral regurgitation (MR) is the first cause of valvular regurgitation in Western countries. Echocardiography is the cornerstone for diagnosing MR and more specifically for establishing its aetiology and mechanism, for quantifying its severity, progression, and repercussion and for assessing the likelihood of successful of valve repair. Two-dimensional/three-dimensional transthoracic and transoesophageal echocardiography <br />are the most widely used methods. Interest is growing for exercise echocardiography particularly in patients in whom symptoms do not correlate well with MR severity and for risk stratification. The experience of multi-slice computed tomography in primary MR is still limited. Conversely, cardiovascular magnetic resonance has gained progressive relevance and represents the alternative method of choice. [less ▲]

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See detailPrognostic Importance of Exercise Brain Natriuretic Peptide in Asymptomatic Degenerative Mitral Regurgitation.
Magne, Julien ULg; Mahjoub, H; Pibarot, P et al

Conference (2012)

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See detailOutcome prediction in asymptomatic degenerative MR: the usefulness of exercise BNP.
Magne, Julien ULg; Mahjoub, H; Pibarot, P et al

Conference (2012)

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See detailGuidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS).
Vahanian, Alec; Alfieri, Ottavio; Andreotti, Felicita et al

in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2012), 42(4), 1-44

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See detailComplications cardiaques de l'acromégalie : cas rare de cardiopathie dilatée
Devoitille, A.; Beckers, Albert ULg; Pierard, Luc ULg

in Revue Médicale de Liège (2012), 67(4), 174-178

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See detailLeft atrial function: pathophysiology, echocardiographic assessment, and clinical applications.
Rosca, M.; Lancellotti, Patrizio ULg; Popescu, B. A. et al

in Heart (2011), 97(23), 1982-9

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See detailL'image du mois: un serpent en liberté.
ANCION, Arnaud ULg; MARCHETTA, Stella ULg; BERTHE, Christian ULg et al

in Revue Médicale de Liège (2011)

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See detailMathematical multi-scale model of the cardiovascular system including mitral valve dynamics. Application to ischemic mitral insufficiency
Paeme, Sabine ULg; Moorhead, Katherine; Chase, J. Geoffrey et al

in BioMedical Engineering OnLine (2011), 10(1), 86

Valve dysfunction is a common cardiovascular pathology. Despite significant clinical research, there is little formal study of how valve dysfunction affects overall circulatory dynamics. Validated models ... [more ▼]

Valve dysfunction is a common cardiovascular pathology. Despite significant clinical research, there is little formal study of how valve dysfunction affects overall circulatory dynamics. Validated models would offer the ability to better understand these dynamics and thus optimize diagnosis, as well as surgical and other interventions. A cardiovascular and circulatory system (CVS) model has already been validated in silico, and in several animal model studies. It accounts for valve dynamics using Heaviside functions to simulate a physiologically accurate “open on pressure, close on flow” law. However, it does not consider real-time valve opening dynamics and therefore does not fully capture valve dysfunction, particularly where the dysfunction involves partial closure. This research describes an updated version of this previous closed-loop CVS model that includes the progressive opening of the mitral valve, and is defined over the full cardiac cycle. Simulations of the cardiovascular system with healthy mitral valve are performed, and, the global hemodynamic behaviour is studied compared with previously validated results. The error between resulting pressure-volume (PV) loops of already validated CVS model and the new CVS model that includes the progressive opening of the mitral valve is assessed and remains within typical measurement error and variability. Simulations of ischemic mitral insufficiency are also performed. Pressure-Volume loops, transmitral flow evolution and mitral valve aperture area evolution follow reported measurements in shape, amplitude and trends. The resulting cardiovascular system model including mitral valve dynamics provides a foundation for clinical validation and the study of valvular dysfunction in vivo. The overall models and results could readily be generalised to other cardiac valves. [less ▲]

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See detailInfluence of thermoelectric coupling on pacemaker activity generated by mechano-electric feedback in a one-dimensional ring-shaped model of cardiac fiber
Collet, Arnaud ULg; Desaive, Thomas ULg; Pierard, Luc ULg et al

in XXIIIrd congress of the International Society of Biomechanics, July 3-7, 2011 (2011, July 05)

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See detailInfluence of thermoelectric coupling on pacemaker activity generated by mechano-electric feedback in a one-dimensional ring-shaped model of cardiac fiber
Collet, Arnaud ULg; Desaive, Thomas ULg; Pierard, Luc ULg et al

Poster (2011, July 05)

Recently, the influence of thermal processes on electrophysiology has clearly been underlined, using a FitzHugh–Nagumo-type (FHN-type) model. When the temperature is raised, the action potential duration ... [more ▼]

Recently, the influence of thermal processes on electrophysiology has clearly been underlined, using a FitzHugh–Nagumo-type (FHN-type) model. When the temperature is raised, the action potential duration (APD) has been shown to shorten, while the action potential (AP) amplitude decreases, and the conduction velocity increases. In the present study, we investigate the effects of thermoelectric coupling on mechano-electric feedback (MEF), and more specifically, on pacemaker activity generated by MEF. To investigate these effects, thermoelectric coupling is introduced in a one-dimensional ring-shaped electromechanical model of cardiac fiber, which takes into account excitation-contraction coupling (ECC), as well as MEF. [less ▲]

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See detailComment j'explore... une insuffisance cardiaque chronique
ANCION, Arnaud ULg; NELLESSEN, Eric ULg; Lancellotti, Patrizio ULg et al

in Revue Médicale de Liège (2011)

Heart failure is defined by precise criteria associating clinical signs and cardiac abnormalities. The exploration for signs and symptoms must be associated with the systematic realization of an ... [more ▼]

Heart failure is defined by precise criteria associating clinical signs and cardiac abnormalities. The exploration for signs and symptoms must be associated with the systematic realization of an electrocardiogram, a chest X-ray and an echocardiogram to rapidly obtain the diagnosis and direct the patient to an adapted complementary clarification. Other additional tests are available (catheterization, nuclear cardiology imaging,...). The purpose is to confirm the diagnosis, to determine the aetiology and to identify factors of poor prognosis. [less ▲]

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See detailInfluence of thermoelectric coupling on pacemaker activity generated by mechano-electric feedback in a one-dimensional ring-shaped model of cardiac fiber
Collet, Arnaud ULg; Desaive, Thomas ULg; Pierard, Luc ULg et al

Poster (2011, June 01)

The mechano-electric feedback (MEF) in the heart consists in the influence of the tissue deformations on the cardiac electrical activity. Under certain conditions, tissue deformations can generate ... [more ▼]

The mechano-electric feedback (MEF) in the heart consists in the influence of the tissue deformations on the cardiac electrical activity. Under certain conditions, tissue deformations can generate electrical perturbations via stretch-activated channels, such that the membrane potential can exceed the threshold value needed in order to trigger cardiac action potentials (APs). In the present study, we have developed a one-dimensional ring-shaped model of cardiac fiber taking into account three different couplings: the excitation-contraction coupling (ECC), the MEF and the thermoelectric coupling (TEC). The main goal of this work is to examine the effects of the TEC on the different properties of the pacemaker activity generated by the MEF. [less ▲]

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