References of "PIERARD, Gérald"
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See detailComment j'explore ... une bouche brulante
Claessens, N.; Pierard-Franchimont, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2000), 55(11), 1011-4

Burning mouth is a symptom typical for the oral mucosa. In contrast, pruritus is absent at this site. The situation which is the reverse on the skin can be explained by microanatomical differences in the ... [more ▼]

Burning mouth is a symptom typical for the oral mucosa. In contrast, pruritus is absent at this site. The situation which is the reverse on the skin can be explained by microanatomical differences in the sensorial innervation and by a different balance between neuromediators. Burning mouth sensation calls for the search of a series of diseases. However, it is most often a monosymptomatic expression of a minimal lichenoid stomatitis. [less ▲]

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See detailLe cas clinique du mois. Fusariose disseminee chez un patient immunodeprime
Quatresooz, Pascale ULg; Meiers, I.; Arrese, J. E. et al

in Revue Médicale de Liège (2000), 55(11), 974-6

Fusarium spp are ubiquitous soil saprophytes and occasional plant pathogens. Fusariosis in humans is usually limited to superficial mycoses. We report the case of a disseminated fungal infection due to ... [more ▼]

Fusarium spp are ubiquitous soil saprophytes and occasional plant pathogens. Fusariosis in humans is usually limited to superficial mycoses. We report the case of a disseminated fungal infection due to Fusarium spp in an immunosuppressed patient suffering from acute lymphoblastic leukemia. This report and review of the recent literature suggest that Fusarium spp are emerging fungal pathogens in immunosuppressed patients. [less ▲]

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See detailTatouages. Du rituel a la parure avec leurs complications
Paquet, Philippe ULg; Pierard, Gérald ULg; Nikkels, Arjen ULg et al

in Revue Médicale de Liège (2000), 55(9), 847-849

Tattoos are performed for distinct purposes which range from social rituals to aesthetic aims. They are permanent or transient according to the site of the pigments being located either in the dermis or ... [more ▼]

Tattoos are performed for distinct purposes which range from social rituals to aesthetic aims. They are permanent or transient according to the site of the pigments being located either in the dermis or in the stratum corneum, respectively. Tattoos may be responsible for allergic reactions, infections or psychological distress of the subject who requests to be relieved of it. [less ▲]

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See detailReactions indesirables au contact d'organismes marins
Letot, Bernard ULg; Kharfi, M.; Mandojana, R. et al

in Revue Médicale de Liège (2000), 55(6), 531-7

The contact of some marine organisms with the skin may prove to be traumatic and sometimes very dangerous. Some coelenterates, fishes, urchins, sea snakes, cephalopods, molluscs and other sea organisms ... [more ▼]

The contact of some marine organisms with the skin may prove to be traumatic and sometimes very dangerous. Some coelenterates, fishes, urchins, sea snakes, cephalopods, molluscs and other sea organisms are responsible for dermatological lesions, associated or not with toxic or allergic reactions exhibiting systemic effects. [less ▲]

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See detailOrientations diagnostiques chez le voyageur au retour d'un pays exotique
Pierard, Gérald ULg

in Revue Médicale de Liège (2000), 55(6), 490-1

On a medical ground, a traveller returning from an exotic country may suffer from three main categories of diseases: fever, diarrhoea and unusual dermatosis. The present review is a synoptic aid at the ... [more ▼]

On a medical ground, a traveller returning from an exotic country may suffer from three main categories of diseases: fever, diarrhoea and unusual dermatosis. The present review is a synoptic aid at the diagnosis. [less ▲]

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See detailApproche factuelle du traitement de l'herpes genital
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2000), 55(5), 430-437

Genital herpes is a sexually transmitted disease. After the primary infection, the virus establishes a life-long latency in the sacral dorsal root ganglia. Recurrences may occur at an unpredictable rate ... [more ▼]

Genital herpes is a sexually transmitted disease. After the primary infection, the virus establishes a life-long latency in the sacral dorsal root ganglia. Recurrences may occur at an unpredictable rate. The clinical signs are not always easy to recognize and viral identification techniques may be helpful such as immunohistochemistry and in situ hybridization on Tzanck smears and muco-cutaneous biopsies. The treatment of genital herpes can follow one of three strategies using antiviral drugs, non-specific immunomodulators, and vaccination. The new oral antiviral drugs decrease the severity of clinical manifestations without, however, providing a definitive cure. In this article recent knowledge about the clinical aspects, differential diagnosis, diagnostic methods, treatment options and management is reviewed. [less ▲]

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See detailRelativite de la prise en charge des cancers cutanes. Plaidoyer pour la synergie entre le medecin generaliste et le dermatologue-oncologue
Pierard, Gérald ULg; Pierard-Franchimont, Claudine ULg; Cornil, F. et al

in Revue Médicale de Liège (2000), 55(4), 247-252

The clinical diagnosis and treatment of cutaneous cancers represent a frequent situation in cancerology. About one third of all human cancers take their origin from the skin. The general practitioner and ... [more ▼]

The clinical diagnosis and treatment of cutaneous cancers represent a frequent situation in cancerology. About one third of all human cancers take their origin from the skin. The general practitioner and the dermatologist-oncologist play the key role in that field of health care. [less ▲]

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See detailSkin Tensile Strength Modulation by Compressive Garments in Burn Patients. A Pilot Study
Fournier, R.; Pierard, Gérald ULg

in Journal of Medical Engineering & Technology (2000), 24(6, Nov-Dec), 277-80

Compression therapy is frequently used to prevent hypertrophy of post-burn scars. This pilot study was performed in 6 patients to assess non-invasive changes induced in the tensile strength of the skin ... [more ▼]

Compression therapy is frequently used to prevent hypertrophy of post-burn scars. This pilot study was performed in 6 patients to assess non-invasive changes induced in the tensile strength of the skin before any clinical improvement can be perceived. Assessments were performed using a computerized suction device delivering three 5 s cycles of 500 mbar depression. Measurements were made at one-month intervals for three months after initiating the garment compression therapy. Comparisons were made between the intact skin, the ungrafted and grafted post-burn scars and the graft donor sites. Data show that garment compression therapy alters the tensile strength in the skin of all test sites. The most reliable variations consist of an increase in both the extensibility and elasticity of the tissues submitted to traction. [less ▲]

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See detailViroses tropicales éruptives
Fraiture, A. L.; Nikkels, Arjen ULg; Pierard-Franchimont, Claudine ULg et al

in Revue Médicale de Liège (2000), 55

Eruptive tropical viroses are severe diseases which may prove to be sometimes fatal diseases. They are characterized by erythémato-purpuric cutaneous lesions associated with hyperthermia. Polyarthralgia ... [more ▼]

Eruptive tropical viroses are severe diseases which may prove to be sometimes fatal diseases. They are characterized by erythémato-purpuric cutaneous lesions associated with hyperthermia. Polyarthralgia or severe haemorrhage can also be part of the clinical presentation. Rapid diagnosis and preventive measures are mandatory, particularly when human transmission is possible. [less ▲]

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See detailExperimental gerontology in Belgium: from model organisms to age-related pathologies
Toussaint, Olivier; Baret, P. V.; Brion, J.-P. et al

in Experimental Gerontology (2000), 35(8), 901-916

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See detailCellulite: from standing fat herniation to hypodermal stretch marks.
Pierard, Gérald ULg; NIZET, Jean-Luc ULg; PIERARD-FRANCHIMONT, Claudine ULg

in American Journal of Dermatopathology (2000), 22(1), 34-7

There are glaring discrepancies in the microanatomical descriptions of cellulite in the literature. We revisited this common skin condition in women with a microscopic examination of 39 autopsy specimens ... [more ▼]

There are glaring discrepancies in the microanatomical descriptions of cellulite in the literature. We revisited this common skin condition in women with a microscopic examination of 39 autopsy specimens. A control group consisted of 4 women and 11 men showing no evidence of cellulite. The lumpy aspect of the dermohypodermal interface appeared to represent a gender-linked characteristic of the thighs and buttocks without being a specific sign of cellulite. Incipient cellulite identified by the mattress phenomenon was related to the presence of focally enlarged fibrosclerotic strands partitioning the subcutis. Such strands possibly serve as a physiologic buttress against fat herniation limiting the outpouching of fat lobules on pinching the skin. These structures might represent a reactive process to sustained hypodermal pressure caused by fat accumulation. Full-blown cellulite likely represents subjugation of the hypertrophic response when connective tissue is overcome by progressive fat accumulation. Histologic aspects reminiscent of stretch marks are identified within the hypodermal strands, resulting in clinical skin dimpling. [less ▲]

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See detailLes Scarabées.
Pierard, Sébastien ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Revue Verviétoise d'Histoire Naturelle (2000), 57

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See detailL'appareil aptychial chez les ammonoïdes.
Pierard, Sébastien ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Association des Géologues Amateurs de Belgique Minibul (2000), 33

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See detailLes rhyncholites.
Pierard, Sébastien ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Association des Géologues Amateurs de Belgique Minibul (2000), 33

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See detailControl of perimenstrual flares of perioral dermatitis by isotretinoin
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Journal of Dermatological Treatment (2000), 11

BACKGROUNDS: Some cases of perioral dermatitis (POD) appear in young women after the interruption of oral contraception. Perimenstrual POD flares may also occur. Blue-brown, post-inflammatory macules and ... [more ▼]

BACKGROUNDS: Some cases of perioral dermatitis (POD) appear in young women after the interruption of oral contraception. Perimenstrual POD flares may also occur. Blue-brown, post-inflammatory macules and atrophic scarring often persist. Conventional treatment modalities include topical and oral tetracyclines, topical metronidazole and oral contraceptives. However, such therapies mau fail or offer only transient results. Isotretinoin efficacy was reported in a patient with difficult-to-treat POD. METHODS: We studied the outcome of a 6-month course of isotretinoin with a 1-year follow-up in 14 women suffering from chronic or recurrent POD refractory to or dependent on long-term conventional treatments. The isotretinoin dosing regiments were based on acne management guidelines. RESULTS: At 1-year follow-up, 12 of 14 (85,7 %) of the women remained free of POD recurrences, one patient (7,1 %) experienced a significant improvement, and one patient (7,1 %) showed only transient improvement during therapy, and rapidly relapsed after completing two 6-month treatment courses. The muco-cutaneous side effects were similar to those already known for isotretinoin. No other adverse effects occured. CONCLUSION: Isotretinoin represents a valuable therapeutic alternative for women suffering from chronic or recurrent POD refractory to or dependent on conventional treatment options. [less ▲]

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See detailAn Appraisal of 18-Fluorodeoxyglucose Positron Emission Tomography for Melanoma Staging
Paquet, Philippe ULg; Henry, Frédérique ULg; Belhocine, Tarik et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (2000), 200(2), 167-9

BACKGROUND: Positron emission tomography (PET scan) using fluorodeoxyglucose (FDG) is increasingly recognized as a reliable diagnostic method to detect metastases of malignant melanoma (MM). OBJECTIVE: To ... [more ▼]

BACKGROUND: Positron emission tomography (PET scan) using fluorodeoxyglucose (FDG) is increasingly recognized as a reliable diagnostic method to detect metastases of malignant melanoma (MM). OBJECTIVE: To compare the diagnostic performance of 18-FDG PET scan to that of conventional imaging. METHODS: A total of 28 assessments were conducted in 24 patients at risk of metastatic MM. Results: The diagnostic accuracy was over 80% and similar for PET scan and conventional imaging. CONCLUSION: Both the specificity and sensitivity of PET scan are high although not perfect. Confrontation of data with anatomical location and clinicopathological findings remains mandatory. [less ▲]

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See detailComment j'explore...une mycobactériose cutanée atypique
Henry, Frédérique ULg; Hayette, Marie-Pierre ULg; Melin, Pierrette ULg et al

in Revue Médicale de Liège (2000), 55(12), 1058-1063

Atypical mycobacteriosis affecting the skin are diverse and their treatments are different as well. These diseases show an increasing prevalence. The contamination occurs from the environment while ... [more ▼]

Atypical mycobacteriosis affecting the skin are diverse and their treatments are different as well. These diseases show an increasing prevalence. The contamination occurs from the environment while interhuman transmission does not occur. [less ▲]

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See detailClinical course and predictive factors for cyclosporin-induced autologous graft-versus-host disease after autologous haematopoietic stem cell transplantation.
Baron, Frédéric ULg; Gothot, André ULg; Salmon, Jean ULg et al

in British Journal of Haematology (2000), 111(3), 745-53

The administration of cyclosporin A (CyA) after autologous haematopoietic stem cell transplantation (HSCT) induces a systemic autoimmune syndrome mimicking graft-vs.-host disease (GVHD). This syndrome ... [more ▼]

The administration of cyclosporin A (CyA) after autologous haematopoietic stem cell transplantation (HSCT) induces a systemic autoimmune syndrome mimicking graft-vs.-host disease (GVHD). This syndrome, termed autologous GVHD has notable anti-tumour activity in animal studies. We intended to induce autologous GVHD with CyA in patients undergoing an autologous HSCT. We prospectively studied 118 patients with miscellaneous malignancies undergoing an autologous HSCT with low-dose CyA to characterize the clinical syndrome, its frequency and clinical course, and to determine the factors affecting its incidence. Patients received CyA from d -1 through to d 28, first starting at 2 mg/kg intravenously and then orally as soon as feasible. The dose was adjusted to achieve pre-dose blood levels around 100 ng/ml. A skin biopsy was performed when a skin rash was observed. Thirty-three percent of the patients developed clinical GVHD: clinical stage 1 in 21 patients, stage 2 in seven patients, and stage 3 in three patients. Although total body irradiation (TBI) or high-dose cyclophosphamide were previously thought to be needed, autologous GVHD occurred in five out of 12 patients (42%) after a preparative regimen with high-dose melphalan alone. Autologous GVHD was significantly more frequent in patients older than 33 years, in patients who had received high doses of granulocyte-macrophage colony forming units (CFU-GM) and in those with a diagnosis of myeloid malignancy, compared with those with lymphoid malignancies or solid tumours. A significant negative association was also found with HLA-DR6. In lymphoma patients, GVHD occurred more frequently in advanced disease than in first or second complete remission (CR1-2) patients. All other factors studied were not predictive for GVHD. In conclusion, CyA-induced GVHD is reproducibly and safely induced with doses of CyA adapted to achieve blood levels around 100 ng/ml. In retrospective analysis, there was no survival advantage for patients with GVHD. Phase III trials with this approach are needed to evaluate its anti-tumoral effect. [less ▲]

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