References of "Michaux, Charles"
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See detailA serological and bacteriological survey of brucellosis in wild boar (Sus scrofa) in Belgium
Grégoire, Fabien ULg; Mousset, Bénédicte ULg; Hanrez, David et al

in BMC Veterinary Research (2012), 8(80),

Brucellosis is frequently reported among wild boar populations in Europe. The aim of the study was to assess the epidemiological situation in Belgium, regarding the steady increase of wild boar ... [more ▼]

Brucellosis is frequently reported among wild boar populations in Europe. The aim of the study was to assess the epidemiological situation in Belgium, regarding the steady increase of wild boar populations over the last decades. Several serological tests were used and compared with culture and IS711 polymerase chain reaction (PCR), to determine the most suitable combination of diagnostic tools for conducting a successful prevalence study in wildlife [less ▲]

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See detailA splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response.
Sartelet, Arnaud ULg; Druet, Tom ULg; Michaux, Charles ULg et al

in PLoS Genetics (2012), 15(3), 1002581

We herein report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle. By resequencing positional candidates, we identify the ... [more ▼]

We herein report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle. By resequencing positional candidates, we identify the causative c124-2A>G splice variant in intron 1 of the RNF11 gene, for which all affected animals are homozygous. We make the remarkable observation that 26% of healthy Belgian Blue animals carry the corresponding variant. We demonstrate in a prospective study design that approximately one third of homozygous mutants die prematurely with major inflammatory lesions, hence explaining the rarity of growth-stunted animals despite the high frequency of carriers. We provide preliminary evidence that heterozygous advantage for an as of yet unidentified phenotype may have caused a selective sweep accounting for the high frequency of the RNF11 c124-2A>G mutation in Belgian Blue Cattle. [less ▲]

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See detailImmune depression of the SJL/J mouse, a radioresistant and immunologically atypical inbred strain.
Glineur, Stéphanie ULg; Antoine-Moussiaux, Nicolas ULg; Michaux, Charles ULg et al

in Immunobiology (2011), 216(1-2), 213-217

As the inbred mouse strain SJL/J displays increased resistance to several pathogens and as its immune system shows multiple specificities, it is tempting to infer a causal link between these observations ... [more ▼]

As the inbred mouse strain SJL/J displays increased resistance to several pathogens and as its immune system shows multiple specificities, it is tempting to infer a causal link between these observations. The first question that comes to mind is whether adaptive immunity plays a role, and a way to answer this question is to see if the resistance phenotype persists when adaptive immunity is depressed. Although it has long been known that irradiation causes repression of leukopoiesis in mice, the technical data available in the literature are of no help in the case of strain SJL/J, because it displays exceptional radioresistance. Here we show that exposure of SJL/J to ∼9Gy, an intensity corresponding to the lethal dose 50 for the species Mus musculus, leads to serious but reversible alteration of leukopoiesis. This conclusion stems from an examination of the effects, 1-11 days post-exposure, of whole-body gamma-ray irradiation on leukocyte populations in the thymus and peripheral blood of young adult females. Immunodepression was most severe 4 days post-exposure. As in other strains, leukocyte populations displayed differential radiosensitivity, B (CD19(+)) cells being most sensitive, T (CD4(+)/CD8(+)) cells moderately sensitive, and natural killer (NK1.1(+)) cells most resistant. Surprisingly, however, the helper/inducer T lymphocytes proved more resistant than the cytotoxic/suppressor T lymphocytes, contrarily to what is observed in other strains. The procedure described will make it possible to refute or establish reliably the existence of causal links between SJL-specific phenotypic traits and immune aberrations and to elucidate further the respective roles of innate and acquired immunity in determining the resistance of this strain to an array of viral diseases. [less ▲]

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See detailBalancing selection of a frame-shift mutation in the MRC2 gene accounts for the outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle.
Fasquelle, Corinne ULg; Sartelet, Arnaud ULg; Li, Wanbo et al

in PLoS Genetics (2009), 5(9), 1000666

We herein describe the positional identification of a 2-bp deletion in the open reading frame of the MRC2 receptor causing the recessive Crooked Tail Syndrome in cattle. The resulting frame-shift reveals ... [more ▼]

We herein describe the positional identification of a 2-bp deletion in the open reading frame of the MRC2 receptor causing the recessive Crooked Tail Syndrome in cattle. The resulting frame-shift reveals a premature stop codon that causes nonsense-mediated decay of the mutant messenger RNA, and the virtual absence of functional Endo180 protein in affected animals. Cases exhibit skeletal anomalies thought to result from impaired extracellular matrix remodeling during ossification, and as of yet unexplained muscular symptoms. We demonstrate that carrier status is very significantly associated with desired characteristics in the general population, including enhanced muscular development, and that the resulting heterozygote advantage caused a selective sweep which explains the unexpectedly high frequency (25%) of carriers in the Belgian Blue Cattle Breed. [less ▲]

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See detailNon-Invasive Methods to Predict Breast Muscle Weight in Slow-Growing Chickens
Larivière, Jean-Marc ULg; Michaux, Charles ULg; Verleyen, Vincent ULg et al

in International Journal of Poultry Sciences (2009), 8(7), 689-691

This experiment aims to compare in vivo breast morphometric and ultrasound measurements, as well as live body weight to predict breast meat weight in slow-growing chickens. Traits included Thoracic ... [more ▼]

This experiment aims to compare in vivo breast morphometric and ultrasound measurements, as well as live body weight to predict breast meat weight in slow-growing chickens. Traits included Thoracic Circumference (TC), Chest Width (CW), Keel Length (KL) and angle (KA), Live Weight (LW), thickness of muscle determined by sonography (TM) and Breast Meat Weight (BMW). Birds were then slaughtered and total breast muscles (Pectoralis major and Pectoralis minor) were dissected and weighed. A linear model including sex effect and the different predictor measurements, as covariates, were adjusted to the data. Homogeneity test of slopes between sexes showed no difference. Means of the traits were 115.58g (±19.72) for BMW, 1031 g (±163.44) for LW, 68.65o (±6.89) for KA, 26.81 cm (±1.57) for TC, 10.40 cm (±0.62) for KL, 4.67 cm (±0.47) for CW and 11.52 mm (±1.11) for TM. All traits were highly correlated to BMW: TC (0.85), LW (0.84), KL (0.81) and TM (0.79), except for KA (0.28) and CW (0.19). Finally, TC, LW, KL and TM appear to be valuable indicators for estimating BMW in slow-growing chickens but KA and CW remain poor predictors [less ▲]

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See detailReproductive Performance of the Ardennaise Chicken Breed under Traditional and Modern Breeding Management Systems
Larivière, Jean-Marc ULg; Michaux, Charles ULg; Farnir, Frédéric ULg et al

in International Journal of Poultry Sciences (2009), 8(5), 446-451

Enhancing the use of traditional chicken breeds is necessary to insure long-term conservation of global genetic diversity in poultry. A logical start in this process is to evaluate performance. The ... [more ▼]

Enhancing the use of traditional chicken breeds is necessary to insure long-term conservation of global genetic diversity in poultry. A logical start in this process is to evaluate performance. The objective of this study was to estimate reproductive traits in the Ardennaise chicken breed under traditional and modern management systems. Reproductive performance indicated lighting programs [Natural (NAT) or Artificial (ART) day length] were highly significant for egg weight, hatchability (p<0.001), early and mid-term embryonic mortality (p<0.01). Feeding treatments [ad libitum (AL) or mild Feed-restriction (FR)] varied greatly with egg weight, hatchability, fertility (p<0.001) and late embryonic mortality (p<0.05). Most precocious age at first egg (23 weeks), longest duration of laying period (>27 weeks), utmost maximum production peak (56.67%), largest egg number (70.13 eggs/hen) and number of chicks hatched (24.10 chicks/hen) were performed under ART-AL. Heaviest egg weight (53.21g), highest fertility (70.20%), greatest hatchability (55.58%), highest liveability during rearing (95.74%) and lay (100%), lowest early (3.51%) and mid-term embryonic mortality (1.17%) were achieved under NAT-AL. To summarize, most of traits studied in the Ardennaise chicken were moderate when compared to those expected by broiler breeders. [less ▲]

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See detailGenetic and non genetic effects on growth traits of West African Dwarf sheep in Benin (West Africa)
Gbangboche, A. B.; Abiola, F. A.; Alimi, S. et al

in Livestock Production Science (2008)

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See detailPlasma concentration of insulin-like growth factor I (IGF-I) in growing Ardenner horses suffering from juvenile digital degenerative osteoarthropathy
Lejeune, Jean-Philippe ULg; Franck, Thierry ULg; Gangl, Monika et al

in Veterinary Research Communications (2007), 31(2), 185-195

Degenerative osteoarthropathy resulting in a reduced active lifespan was observed in Ardenner horses. In the context of joint biology, insulin-like growth factor I (IGF-I) is a potential candidate to ... [more ▼]

Degenerative osteoarthropathy resulting in a reduced active lifespan was observed in Ardenner horses. In the context of joint biology, insulin-like growth factor I (IGF-I) is a potential candidate to affect the anabolism of cartilage matrix molecules. A group of 30 Ardenner horses reared under standardized conditions from weaning were evaluated periodically from 15 to 28 months of age to detect the early manifestations of the disease. At the end of this period, horses were classified in two pathological groups related to the degree of interphalangeal degenerative osteoarthropathy based on clinical and radiographic evaluations: healthy (46.7%) and pathological (53.3%) horses. Seven sequential blood samples were taken from each horse (during the evaluation period) to study the variation of IGF-I plasma concentration. We tested the variations of the IGF-I plasma concentration during growth, and the effect of sex and of pathological classes. Significant variations were observed during the research period, with a maximum value corresponding to spring and a minimum in autumn. A significant reduction of the IGF-I plasma concentration was also observed in the pathological horses (433.5 +/- 19.5 ng/ml) compared to the healthy horses (493.9 +/- 18.2 ng/ml). An alteration in the level of this growth factor could induce a disregulation of the mechanisms involved in the local control of joint and bone tissue development. [less ▲]

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See detailProduire de la viande et du lait avec la Blanc-Bleu Belge de type mixte
Bastin, Catherine ULg; Mayeres, Patrick; Bertozzi, Carlo et al

in 12ième Carrefour des Productions animales: Le marché de la viande bovine, enjeux et perspectives: Gembloux, le 24 janvier 2007 (2007, January 24)

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See detailProduire de la viande et du lait avec la Blanc-Bleu Belge de type mixte
Bastin, Catherine ULg; Mayeres, Patrick; Bertozzi, Carlo et al

Poster (2007, January 24)

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See detailGenetic evaluation for birth traits in dual-purpose Belgian Blue using a mixed inheritance model
Mayeres, Patrick; Verkenne, C; Michaux, Charles ULg et al

Diverse speeche and writing (2007)

In this study a genetic evaluation, based on a mixed inheritance model, was developed for birth traits (calving ease, gestation length and birth weight) in dual-purpose Belgian Blue (dpBB), a separated ... [more ▼]

In this study a genetic evaluation, based on a mixed inheritance model, was developed for birth traits (calving ease, gestation length and birth weight) in dual-purpose Belgian Blue (dpBB), a separated type inside Belgian Blue Herd-book. About 80% of dpBB animals have a single or a double copy of the muscular hypertrophy gene. This heterogeneity is the reason of a great variability in birth performance traits like calving ease or birth weight. The muscular hypertrophy gene substitution and dominance effects for calf genotype had a significant impact both on birth weight and calving ease, in accordance with partially recessive expression of the muscular hypertrophy gene. Observed high heritability estimates of direct calving ease (0.334) and birth weight (0.260) suggested that a large genetic variability for birth traits was present in dpBB, and that genetic improvement was possible through selection. This variability has allowed dpBB breeders to apply mass selection successfully in the past. However analysis of breeding values showed that a sire selection for calving ease within genotype was progressively applied by breeders, the selection intensity being more important for calving ease in double muscled lines. This study illustrated the possible confusion that can appear by the use of a major gene in selection, and the importance to use appropriated models combining polygenic and monogenic information, like mixed inheritance models. [less ▲]

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See detailExamination of non-genetic factors affecting the growth performance of Djallonke sheep in soudanian zone at the Okpara Breeding farm of Benin
Gbangboche, A. B.; Youssao, A. K. I.; Adamou-Ndiaye, M. et al

in Tropical Animal Health and Production (2006), 38

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See detailEtude des variables spirométriques et des mesures morphométriques des veaux croisés Blanc-Bleu Belge x Holsteins pie noire
Jacqmot, Olivier ULg; Michaux, Charles ULg; Borceux, Ph et al

in Annales de Médecine Vétérinaire (2004), 148(1), 39-46

The bovine species is highly susceptible to respiratory dis-eases. A previous experiment has shown that Belgian Blue and White calves have lower spiro-metric variables than Holstein calves. The first aim ... [more ▼]

The bovine species is highly susceptible to respiratory dis-eases. A previous experiment has shown that Belgian Blue and White calves have lower spiro-metric variables than Holstein calves. The first aim of this study was to measure the spirometric variables (peak inspiratory flow, peak expiratory flow, maximal tidal volume, maximal ventilation in 15 seconds and ventilatory reserve) of 18 crossed Belgian Blue x Holstein calves and of 32 Dual purpose calves by the lobelin test and to compare them with 19 Holstein calves and 22 Belgian Blue and White calves. The second aim was to test the correlation between some mor-phometrical parameters (chest girth, thoracic width, thoracic length, thoracic height, thoracic section and costal angle) and those spirometric variables. The spirometric variables of the crossed calves and of the Dual purpose calves are situated between the ones of the Belgian Blue and White and of the Holstein. There is a positive sig-nificant correlation between these parameters and the spirometric variables. The higher cor-relation is obtained with the chest girth. All these parameters are easier and quicker measura-ble, and at lower cost than the spirometric variables [less ▲]

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See detailEvolution of blood parameters during weight loss in experimental obese Beagle dogs.
Diez, Marianne ULg; Michaux, Charles ULg; Jeusette, Isabelle et al

in Journal of Animal Physiology & Animal Nutrition (2004), 88(3-4), 166-71

The effects of weight loss on hormonal and biochemical blood parameters were measured monthly [carnitine, creatinine, urea, free T4 (fT4), total T4 (TT4), plasma alkaline phosphatases (ALP), aspartate ... [more ▼]

The effects of weight loss on hormonal and biochemical blood parameters were measured monthly [carnitine, creatinine, urea, free T4 (fT4), total T4 (TT4), plasma alkaline phosphatases (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), potassium and total proteins] or bimonthly [cholesterol, triglycerides, non-esterified fatty acids (NEFA), insulin-like growth factor I (IGF-I), glucose, insulin] in eight obese Beagles dogs fed either a high protein dry diet, DP (crude protein 47.5%, on dry matter basis) or a commercial high fibre diet, HF (crude protein 23.8%, crude fibre 23.3%). The dogs were allotted to two groups according to sex and body weight (BW) and they were respectively fed with the DP or the control HF diet during 12-26 weeks, until they reach their optimal BW. The plasma basal triglycerides and cholesterol concentrations were decreased by the two diets but the difference was only significant for the DP diet. The plasma mean NEFA concentration increased regularly over the period with the HF diet, without significant difference between the two diets. No effect of diet or weight loss was observed on plasma carnitine, urea, creatinine, ALP, AST, ALT, potassium, TT4, FT4, IGF-I, glucose and insulin. Weight loss induced a decrease in fT4 plasma concentration (p < 0.001). The high protein diet allowed a safe weight loss. [less ▲]

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See detailPrédiction du gras intermusculaire du porc Piétrain par l'ultrasonographie en temps réel
Youssao, A. K. I.; Verleyen, Vincent ULg; Michaux, Charles ULg et al

in Viandes & Produits Carnés - Hors série "10èmes journée Sciences du Muscle et Technologies des Viandes" (2004)

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