References of "Melin, Pierrette"
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See detailPrevalence of ermB, ermTR and mefA/B gene classes among erythromycine resistant group B streptococcus isolates collected in Belgium
MELIN, Pierrette ULg; Rodriguez Cuns, Grisel; Tsobo, Chantal et al

Poster (2001, October)

Background: Emergence of erythromycin (Er) and clindamycin (C) resistance (R) observed in GBS, is currently becoming recognized. Methods: Clinical isolates were obtained from a Belgian surveillance for ... [more ▼]

Background: Emergence of erythromycin (Er) and clindamycin (C) resistance (R) observed in GBS, is currently becoming recognized. Methods: Clinical isolates were obtained from a Belgian surveillance for invasive GBS disease in newborns and adults in 1996-1998 (N1=235) and from consecutive specimens submitted, during 1999-2000, to the University hospital of Liege (N2=165). MICs of Er were determined buy using Etest® strip (interpretive criteria of NCCLS). Furthermore, for the ErR isolates, the inducible (iMLS), constitutive (cMLS) and M phenotypes were assessed by disk diffusion and by a double-disk test; the distribution of genes encoding RNA methylases and efflux pumps was investigated by PCR. Results: Of the N1 and N2 isolates, 16 (6.8%) and 19 (11.5%) were respectively R to Er. Among these 35 ErR isolates, 21 (60%) exhibited the cMLS phenotype. They demonstrated a high level R to Er with MICs ranging from 16 to >256 mg/L. The ermB gene was harbored by 19/21 isolates, the ermTR gene by 1 isolate and both ermB and ermTR were present in another isolate. The iMLS phenotype was observed in 10 (29%) ErR isolates; the ermTR gene was present in all isolates except one harboring an ermTR gene. These strains demonstrated low level of R to Er, with MICs of 1-12 mg/L. All 4 isolates (11%) expressing an M phenotype, displayed low level R to Er alone (MICs, 2 mg/L) and were positive for the mefA/B gene. Conclusion: In Belgium, by year 2000, prevalence of R to macrolide in GBS exceeded 10%. R was mainly caused by target-site modification (ermB, ermTR) mechanisms; efflux (mefA/B) R mechanism was also prevalent among the isolates tested. These results indicate the possibility of inappropriate prophylaxis or therapy using C or E as the recommended alternatives in penicillin-allergic patients. [less ▲]

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See detailAutomation in Identification and Susceptibility Testing
Melin, Pierrette ULg; De Mol, Patrick ULg

Conference (2001, June 14)

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See detailAutomatisation in blood cultures
Melin, Pierrette ULg; De Mol, Patrick ULg

Conference (2001, June 14)

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See detailDetection of Aspergillus spp. by PCR in Bronchoalveolar Lavage Fluid
Hayette, Marie-Pierre ULg; Vaira, Dolorès ULg; Suzin, Fabrice et al

in Journal of Clinical Microbiology (2001), 39(6), 2338-2340

The usefulness of a nested PCR assay for detection of Aspergillus sp. DNA was evaluated in 177 bronchoalveolar lavage (BAL) fluid specimens. This test was accurate both to diagnose culture-negative BAL ... [more ▼]

The usefulness of a nested PCR assay for detection of Aspergillus sp. DNA was evaluated in 177 bronchoalveolar lavage (BAL) fluid specimens. This test was accurate both to diagnose culture-negative BAL fluid specimens from patients with invasive pulmonary aspergillosis and to confirm culture-positive samples. However, it did not differentiate between infection and colonization. [less ▲]

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See detailIntérêt et techniques de dépistages des infections virales
Melin, Pierrette ULg

Scientific conference (2001, March 19)

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See detailPrevention of neonatal group B streptococcal disease in Belgium: hospital policy, obstetricians' practice and laboratory processing
MELIN, Pierrette ULg; Schmitz, Myriam; Heinrichs, I. et al

Poster (2000, November 25)

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See detailAntimicrobial Susceptibility of Streptococcus agalactiae Isolated from Patients in Belgium Through 1989-1991 and 1996-1999
MELIN, Pierrette ULg; Rodriguez Cuns, Grisel; Vincento Fernandez, Walter et al

in Martin, Diana R.; Tagg, John R. (Eds.) Streptococci and Streptococcal Diseases Entering the New Millenium - Proceeding of the XIV LISSSD (2000, November)

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See detailSerotype Distribution of Invasive Streptococcus agalactiae Isolated from Neonates and Adults in Belgium over a 4-years Period (1995-1999)
Melin, Pierrette ULg; De Mol, Patrick ULg

in Martin, Diana R; Tagg, John R (Eds.) Streptococci and Streptococcal Diseases - Entering the New Millenium", Proceedings of the XIV Lancefield International Symposium on Streptococci and Streptococcal Diseases (2000)

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See detailAntimicrobial Susceptibility of Streptococcus agalactiae Isolated from Patients in Belgium through 1989-1991 and 1996-1999
Melin, Pierrette ULg; Rodriguez Cuns, Grisel; Vicentino Fernandez, Walter et al

in Martin, Diana R; Tagg, John R (Eds.) Streptococci and Streptococcal Diseases - Entering the New Millenium", Proceedings of the XIV Lancefield International Symposium on Streptococci and Streptococcal Diseases (2000)

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Peer Reviewed
See detailSerotype distribution of invasive Streptococcus agalactiae isolated from neonates and adults in Belgium over a 4-year period (1995-1999)
MELIN, Pierrette ULg; De Mol, Patrick ULg

in Martin, Diana R.; Tagg, John R. (Eds.) Streptococci and Streptococcal Diseases Entering the New Millenium - Proceeding of the XIV LISSSD (2000, November)

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See detailStrep B OIA and prenatal cultures for identification of GBS carriers at delivery
Melin, Pierrette ULg

Conference (2000, October 31)

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See detailPrévention des infections périnatales à streptocoques du groupe B.
Melin, Pierrette ULg

Scientific conference (2000, October 05)

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