References of "Mc Entee, Kathleen"
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See detailUse of ciliogenesis in the diagnosis of primary ciliary dyskinesia in a dog
Clercx, Cécile ULg; Peeters, Dominique ULg; Beths, T. et al

in Journal of the American Veterinary Medical Association [=JAVMA] (2000), 11

Primary ciliary dyskinesia is a congenital condition that may cause chronic rhinitis and bronchopneumonia. Primary ciliary dyskinesia may be diagnosed by induction of ciliogenesis by use of in vitro cell ... [more ▼]

Primary ciliary dyskinesia is a congenital condition that may cause chronic rhinitis and bronchopneumonia. Primary ciliary dyskinesia may be diagnosed by induction of ciliogenesis by use of in vitro cell culture. Induction of ciliogenesis allows for differentiation between primary and secondary ciliary dyskinesia. [less ▲]

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See detailDoppler Echocardiographic Study of Left and Right Ventricular Function During Dobutamine Stress Testing in Conscious Healthy Dogs
Mc Entee, Kathleen ULg; Clercx, Cécile ULg; Amory, Hélène ULg et al

in American Journal of Veterinary Research (1999), 60(7), 865-71

OBJECTIVE: To evaluate left and right ventricular filling and ejection performances by use of Doppler echocardiography in healthy, conscious dogs submitted to dobutamine stress testing. ANIMALS: 10 ... [more ▼]

OBJECTIVE: To evaluate left and right ventricular filling and ejection performances by use of Doppler echocardiography in healthy, conscious dogs submitted to dobutamine stress testing. ANIMALS: 10 unsedated, healthy adult Beagles. PROCEDURE: Doppler echocardiography was performed during cardiac stress testing on each dog twice at 24-hour intervals. Dobutamine was infused in 10 micrograms/kg of body weight/min incremental dosages, from 12.5 to 42.5 micrograms/kg/min. Duration of each step was 15 minutes. Doppler measurements were recorded at baseline and at each stage of dobutamine infusion, whereas aortic diameter was measured at baseline and at peak dosage by use of two-dimensional echocardiography. RESULTS: Dobutamine infusion induced a significant increase in velocity time integrals and in peak flow velocities at the aortic, pulmonic, mitral, and tricuspid valves. Acceleration time-to-deceleration time ratio at the aortic wave also was increased significantly. On the other hand, ejection time, acceleration time, and deceleration time at the aortic and pulmonic valves and peak flow velocity of the E wave-to-peak flow velocity of the A wave ratio at the mitral and tricuspid valves decreased significantly during the test. The acceleration time-to-deceleration time ratio at the pulmonic wave was unchanged. A significant, progressive increase in cardiac index also was observed during dobutamine infusion, with a maximal increase of 104% from baseline. This was mediated initially by an increase in stroke index and, at higher dosages, by an increase in heart rate. CONCLUSIONS AND CLINICAL RELEVANCE: Doppler echocardiography performed during dobutamine stress testing may be a reliable method of assessing myocardial function in dogs with cardiovascular disease. [less ▲]

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See detailNonresponsive Generalized Bacterial Infection Associated with Systemic Lupus Erythematosus in a Beauceron
Clercx, Cécile ULg; Mc Entee, Kathleen ULg; Gilbert, S. et al

in Journal of the American Animal Hospital Association (1999), 35(3, May-Jun), 220222224-8

A case of concurrent canine systemic lupus erythematosus (SLE) and generalized bacterial infection in a six-year-old female Beauceron is reported. The dog presented with purulent nasal and ocular ... [more ▼]

A case of concurrent canine systemic lupus erythematosus (SLE) and generalized bacterial infection in a six-year-old female Beauceron is reported. The dog presented with purulent nasal and ocular discharges, skin lesions (including seborrhea, hyperkeratotic areas, and papules as well as ecchymoses around the eyes, on both sides of the pinnae, and on the vulva), generalized lymph node enlargement, a mitral murmur, and lameness. Later, facial swelling, a retrobulbar abscess, and a cough also developed. Occurrence of a generalized bacterial infection was established by culture of group-C, beta-hemolytic Streptococcus from the throat, the mouth, a biopsy site (popliteal lymph node area), the retrobulbar abscess, and the lung. The diagnosis of SLE was based on the clinical signs and particularly on the occurrence of antinuclear antibody (ANA) and antidoublestranded-desoxyribonucleic acid (ds-DNA) antibody. Interestingly, the latter type of antibodies were also detected in two young female puppies whelped by this dog. Salient histological findings included an extreme cell depletion of the lymph nodes and spleen and severe pneumonitis and peribronchiolitis. The results of this case indicate that a definite diagnosis of canine SLE can, at times, be made on the basis of the presence of serum ANA and ds-DNA antibodies. [less ▲]

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See detailPhysiologic Response to Dobutamine Infusion During Cardiac Stress Testing of Dogs
Mc Entee, Kathleen ULg; Amory, Hélène ULg; Clercx, Cécile ULg et al

in American Journal of Veterinary Research (1998), 59(9), 1160-5

OBJECTIVE: To evaluate response of various cardiovascular variables after administration of incremental doses of dobutamine in healthy conscious dogs, using standardized dobutamine stress echocardiography ... [more ▼]

OBJECTIVE: To evaluate response of various cardiovascular variables after administration of incremental doses of dobutamine in healthy conscious dogs, using standardized dobutamine stress echocardiography (DSE). ANIMALS: 8 healthy dogs. PROCEDURE: A DSE was performed twice on each dog within 24 hours. Dobutamine was infused at a rate of 12.5 to 42.5 microg/kg/min, using incremental increases of 10 microg/kg/min. Doppler sphygmomanometry, electrocardiography, and echocardiography were performed. Left ventricular size, global ventricular performance, and left ventricular systolic myocardial function were measured by means of echocardiography. RESULTS: At the highest dosage, dobutamine induced an increase of 20+/-3% and 109+/-12% in systolic blood pressure and cardiac index, respectively. The latter was associated with a significant increase in heart rate and stroke index. Fractional shortening of the left ventricle, fractional thickening of the left ventricular free wall and interventricular septum, ejection fraction, and mean velocity of fiber shortening had a progressive and significant increase during dobutamine infusion. Preejection period and left ventricular ejection time had a progressive and significative decrease during the stress test. CONCLUSIONS: The technique used was feasable, safe, and repeatable in healthy conscious dogs. Control values were determined. CLINICAL RELEVANCE: Data for these healthy dogs might be useful for comparison with results obtained from dogs with known or suspected cardiovascular disease. [less ▲]

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See detailDobutamine stress testing in a canine model of progressive heart failure by rapid ventricular pacing: preliminary results
Mc Entee, Kathleen ULg; Clercx, Cécile ULg; Balligand, Marc ULg et al

in 8th ESVIM Meeting - Vienne - Autriche - septembre 1998 (1998, September)

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See detailLaryngeal Rhabdomyoma in a Golden Retriever
Clercx, Cécile ULg; Desmecht, Daniel ULg; Michiels, L. et al

in Veterinary Record : Journal of the British Veterinary Association (1998), 143(7), 196-8

A three-year-old male golden retriever had had progressive dyspnoea, exercise intolerance, stridor, and a modified bark for five months. A mass 2 cm in diameter was present dorsal to the right side of the ... [more ▼]

A three-year-old male golden retriever had had progressive dyspnoea, exercise intolerance, stridor, and a modified bark for five months. A mass 2 cm in diameter was present dorsal to the right side of the larynx. Histological examination revealed cross-striations in some elongated cells, consistent with a diagnosis of rhabdomyoma, a diagnosis which was confirmed by positive immunohistochemical staining for myoglobin and desmin. The mass could not be removed without total laryngectomy and a permanent tracheostomy and the dog was euthanased. [less ▲]

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See detailEffects of Dobutamine on Isovolumic and Ejection Phase Indices of Cardiac Contractility in Conscious Healthy Dogs
Mc Entee, Kathleen ULg; Amory, Hélène ULg; Pypendop, B. et al

in Research in Veterinary Science (1998), 64(1, Jan-Feb), 45-50

The aim of this study was to determine cardiac contractility using indices derived from cardiac catheterisation in conscious healthy dogs during dobutamine infusion. Eight dogs were studied. An ECG was ... [more ▼]

The aim of this study was to determine cardiac contractility using indices derived from cardiac catheterisation in conscious healthy dogs during dobutamine infusion. Eight dogs were studied. An ECG was recorded together with left ventricular pressure and volume which were measured using a conductance catheter with an integrated microtip pressure sensor. Eight indices of left ventricular systolic performance were derived from these records. Measurements were realised under basal conditions and during an incremental dobutamine challenge. The maximal rate of rise in ventricular pressure (max dP/dt), max dP/dt divided by the developed pressure and the mean systolic ejection rate were the most sensitive indices to detect dobutamine induced changes in contractility with maximal percentage changes of 122+/-11 per cent, 130+/-7 per cent and 102+/-24 per cent respectively. Ejection fraction increased significantly during dobutamine infusion (maximal percentage change of 43+/-9 per cent) whereas the pre-ejection period (PEP) and the left ventricular ejection time (LVET) decreased significantly (maximal percentage change of -41+/-2 per cent and -28+/-3 per cent respectively). All these six indices were significantly correlated with each other. Conversely, the ratio PEP/LVET and the LVET corrected for heart rate dependency showed a maximal percentage change of only -10+/-1 per cent and -16+/-7 per cent, respectively, during the dobutamine infusion and were not significantly correlated with the other contractility indices. This study demonstrated the feasibility of the conductance method to determine cardiac contractility in conscious healthy dogs submitted to a pharmacological stress testing and provides control values for eight indices of left ventricular contractility during dobutamine infusion at increasing dosages. [less ▲]

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See detailClinical Vignette. Tetralogy of Fallot Associated with a Patent Ductus Arteriosus in a German Shepherd Dog
Mc Entee, Kathleen ULg; Snaps, Frédéric ULg; Clercx, Cécile ULg et al

in Journal of Veterinary Internal Medicine (1998), 12(1, Jan-Feb), 53-5

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See detailEosiniphilic bronchopulmonary disease in dogs (EBP): a clinical analysis of 25 cases.
Clercx, Cécile ULg; Snaps, Frédéric ULg; Peeters, Dominique ULg et al

in Proceedings of the 8th Annual Congress of the ESVIM (1998)

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See detailPrimary ciliary dyskinesia in a Bull Mastiff.
Clercx, Cécile ULg; Peeters, Dominique ULg; Beths, Thierry et al

in Proceedings of the 7th Annual Congress of the ESVIM (1997)

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See detailSignes cliniques et diagnostic des tumeurs de la cavité nasale chez le chien: une analyse de 81 cas.
Clercx, Cécile ULg; Peeters, Dominique ULg; Gilbert, S. et al

in Annales de Médecine Vétérinaire (1997), 141

The paper describes clinical signs and diagnosis in 81 cases of intranasal tumors n the dog, examined at the Small Animal Clinic of the Faculty of Veterinary Medicine of the University of Liege (1990-1995 ... [more ▼]

The paper describes clinical signs and diagnosis in 81 cases of intranasal tumors n the dog, examined at the Small Animal Clinic of the Faculty of Veterinary Medicine of the University of Liege (1990-1995). Recent diagnostic techniques and therapeutic options are discussed. The most frequently encountered signs included a decreased or absence of unilateral air passage, observed in 78 cases (96%), and hemorrhagic discharge, observed in 65 cases (80%). Histopathology identified 2 benign and 79 malignant tumors, 57 epithelial and 22 mesenchymatous, including 2 lymphomas. In 74 cases, rhinoscopy identified an intranasal neoplastic mass; in the 7 remaining cases, tissular material of undetermined nature was observed, and histology of biospsied material confirmed the neoplastic nature. The time interval between the diagnosis and the death of the animal (spontaneous or by euthanasia) was longer in dogs with an intranasal sarcoma (mean time interval of 7 months) than in dogs with an intranasal carcinoma (mean time interval of 3 months). [less ▲]

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See detailCardiac Performance in Conscious Healthy Dogs During Dobutamine Infusion
Mc Entee, Kathleen ULg; Clercx, Cécile ULg; Pypendop, B. et al

in Research in Veterinary Science (1996), 61(3), 234-9

The aim of this study was to determine the cardiac performance of conscious healthy dogs during stimulation with dobutamine. Eight healthy unsedated beagle dogs were used. Cardiac output was measured by ... [more ▼]

The aim of this study was to determine the cardiac performance of conscious healthy dogs during stimulation with dobutamine. Eight healthy unsedated beagle dogs were used. Cardiac output was measured by the thermodilution technique and blood pressures by extravascular pressure transducers. Dobutamine challenge at a dosage ranging from 27.5 to 50 micrograms kg-1 min-1 induced a significant rise in cardiac power index (CPI), cardiac index (CI), stroke index (SI) and heart rate (HR) and a significant decrease in pulmonary vascular resistance (PVR) and systemic vascular resistance (SVR). The highest CPI was 2.05 times greater than its basal resting value. The CI was primarily responsible for this increase in CPI. The SI and HR contributed approximately 55 per cent and 45 per cent respectively of the maximal increase in CI. [less ▲]

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See detailDobutamine cardiac stress testing in conscious healthy dogs
Mc Entee, Kathleen ULg; Amory, Hélène ULg; Pypendop, B. et al

in 6th ESVIM Meeting - Velhoven - Septembre 1996 (1996, September)

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See detailBronchopulmonary and Disseminated Granulomatous Disease Associated with Aspergillus Fumigatus and Candida Species Infection in a Golden Retriever
Clercx, Cécile ULg; Mc Entee, Kathleen ULg; Snaps, Frédéric ULg et al

in Journal of the American Animal Hospital Association (1996), 32(2, Mar-Apr), 139-45

A seven-year-old, female golden retriever was referred for a paroxysmal, chronic cough and dyspnea, dysphagia, facial pruritus, anterior uveitis, and deteriorating general condition. A severe, mixed ... [more ▼]

A seven-year-old, female golden retriever was referred for a paroxysmal, chronic cough and dyspnea, dysphagia, facial pruritus, anterior uveitis, and deteriorating general condition. A severe, mixed interstitial and alveolar pattern, with poorly defined amorphous lesions, was seen on thoracic radiographs. Multiple, whitish nodules disseminated on the hyperemic respiratory mucosa were noted on bronchoscopy. Escherichia coli and Aspergillus fumigatus were cultured from the bronchoalveolar lavage. Granulomatous lesions in numerous organs were identified during necropsy, and Aspergillus fumigatus and Candida spp. were cultured from lung and kidney tissues. Microscopic granulomatous lesions were compatible with mycotic infection; however fungal organisms were not observed. [less ▲]

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See detailClosantel Intoxication in a Dog
Mc Entee, Kathleen ULg; Grauwels, Magda ULg; Clercx, Cécile ULg et al

in Veterinary and Human Toxicology (1995), 37(3), 234-6

A case of overdosage with closantel, a salicynalide derivative, in a dog is described. The dog received 6 times the recommended dosage. Closantel induced optic neuritis, retinal degeneration, partial ... [more ▼]

A case of overdosage with closantel, a salicynalide derivative, in a dog is described. The dog received 6 times the recommended dosage. Closantel induced optic neuritis, retinal degeneration, partial deafness, hepatotoxicosis and myopathy. Only the blindness was irreversible. The therapy included albumin administration to reduce the acute toxicity of closantel. [less ▲]

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See detailComparative assessment of right ventricular performance from the pressure-volume relationship in double-muscled and conventional calves.
Amory, Hélène ULg; Mc Entee, Kathleen ULg; Linden, Annick ULg et al

in Canadian Journal of Veterinary Research = Revue Canadienne de Recherche Vétérinaire (1995), 59(2), 135-141

Forty-one and 55 records of right-sided and systemic arterial pressures, cardiac output, and end-diastolic and end-systolic right ventricular volumes were collected from a group of 6 conventional and 6 ... [more ▼]

Forty-one and 55 records of right-sided and systemic arterial pressures, cardiac output, and end-diastolic and end-systolic right ventricular volumes were collected from a group of 6 conventional and 6 double-muscled calves, respectively. In each group, the mean right ventricular pressure-volume loop was constructed. Global cardiac performance was significantly lower in the double-muscled than in the conventional calves. The right ventricular end-diastolic and end-systolic volumes, as well as the diastolic portion of the mean pressure-volume loop, were similar in the 2 groups. Those results suggest that the reduced cardiac performance of double-muscled calves is not due to a lowered ventricular preload and that diastolic properties of their myocardium are similar to those of conventional calves. When expressed on a body weight basis, however, the right ventricular end-diastolic and end-systolic volumes were lower in the double-muscled than in conventional calves. When expressed as a function of probable metabolic demand, therefore, the volumetric capacity of the cardiac pump appears to be reduced in double-muscled calves. The significantly lower right ventricular ejection fraction, maximal rate of ventricular pressure rise and right ventricular peak-systolic pressure to end-systolic volume ratio measured in double-muscled as compared with conventional calves suggest that reduced myocardial contractility may also be partly responsible for the significantly lower stroke index of the former calves. The cardiac pump of double-muscled cattle thus seems to be less effective than that of conventional cattle because of reduced volumetric capacity and lowered strength of contraction. [less ▲]

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See detailMaximal cardiac pumping capacity in double-muscled cattle as determined by a pharmacological test
Amory, Hélène ULg; Mc Entee, Kathleen ULg; Linden, Annick ULg et al

in Pflügers Archiv : European Journal of Physiology (1995), 430

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