References of "Mc Entee, Kathleen"
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See detailSerum endothelin-1 concentration in terrier dogs with idiopathic pulmonary fibrosis.
Krafft, Emilie ULg; Heikkilä, H.; Jespers, P. et al

in Proceedings of the 28th ACVIM Forum (2010, June)

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See detailEvaluation of the influence of age on pulmonary arterial pressure by use of right ventricular catheterization, pulsed-wave Doppler echocardiography, and pulsed-wave tissue Doppler imaging in healthy Beagles.
Mercier, Elise ULg; Mathieu, Myrielle; Sandersen, Charlotte ULg et al

in American Journal of Veterinary Research (2010), 71(8), 891-7

OBJECTIVE: To assess the influence of age on pulmonary hemodynamics and hemorheological properties in healthy dogs. ANIMALS: 14 healthy Beagles. PROCEDURES: Dogs were placed in 2 age groups as follows ... [more ▼]

OBJECTIVE: To assess the influence of age on pulmonary hemodynamics and hemorheological properties in healthy dogs. ANIMALS: 14 healthy Beagles. PROCEDURES: Dogs were placed in 2 age groups as follows: young dogs (<or= 5 years old; n = 8) and old dogs (>or= 8 years old; 6). Hematologic characteristics, plasma total protein and fibrinogen concentrations, and blood viscosity were measured. Systolic time intervals of pulmonary blood flow were recorded by pulsed-wave Doppler echocardiography. Early (E') and late (A') diastolic myocardial velocities, isovolumic contraction velocity, and systolic myocardial velocity of the free tricuspid annulus were recorded by pulsed-wave tissue Doppler imaging (TDI). Dogs were anesthetized and pulmonary arterial pressures (PAP) and cardiac output were recorded with a pediatric thermodilution Swan-Ganz catheter. RESULTS: Hemorheological measurements were not different between the 2 groups. Systolic, mean, and diastolic PAP were higher in old dogs, compared with values in young dogs; this difference was attributed to a high pulmonary vascular resistance and low arterial compliance in old dogs. Systolic time intervals of pulmonary blood flow stayed unchanged. The A' wave of the free tricuspid annulus was increased in old, compared with that young dogs, and the E':A' ratio was decreased. Pulmonary vascular resistance was inversely correlated with compliance. CONCLUSIONS AND CLINICAL RELEVANCE: The age of dogs should be taken into account when interpreting pulmonary hemodynamic results and TDI variables of right ventricular diastolic function. [less ▲]

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See detailSerum endothelin-1 concentration in terrier dogs with idiopathic pulmonary fibrosis.
Krafft, Emilie ULg; Heikkilä, H.; Jespers et al

in Proceedings of the 35th Annual WSAVA Congress (2010)

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See detailEndothelin-1 as a serum biomarker in idiopathic pulmonary fibrosis in dogs
Krafft, Emilie ULg; Heikkilä, H.P.; Jespers, P. et al

in Proceedings of the 20th ECVIM-CA Congress (2010)

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See detailIs transforming growth factor- beta 1 involved in the pathogenesis of IPF in dogs ?
Krafft, Emilie ULg; Heikkilä, H. P.; De Lorenzi, D. et al

in Proceedings of the 20th Annual Congress of the ECVIM-CA (2010)

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See detailProcollagen Type-III aminoterminal peptide in serum, bronchoalveolar lavage fluid and bronchial brush specimens in a model of chronic bronchitis in dogs
Lonneux, M.; Bolognin, M.; Jespers, P. et al

in 19h ECVIM Meeting - Porto, Portugal - 8-10 septembre 2009 (2009, September 08)

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See detailCardiac Power Output during Dobutamine Stress
Sandersen, Charlotte ULg; Mc Entee, Kathleen ULg; Deleuze, Stefan ULg et al

in Journal of Equine Veterinary Science (2009)

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See detailComparison of bronchoalveolar lavage cytospins and smears in dogs and cats.
Dehard, Sandrine ULg; Bernaerts, Frederique ULg; Peeters, Dominique ULg et al

in Journal of the American Animal Hospital Association (2008), 44(6), 285-94

Differences in the cytological interpretation of bronchoalveolar lavage fluid (BALF) after cytospin preparation (CP) or manual smearing of pelleted cells preparation (MSP) were investigated in client ... [more ▼]

Differences in the cytological interpretation of bronchoalveolar lavage fluid (BALF) after cytospin preparation (CP) or manual smearing of pelleted cells preparation (MSP) were investigated in client-owned dogs and cats with inflammatory or infectious lower respiratory disease. Bronchoalveolar lavage fluid from healthy cats was also examined. With MSP, cell lysis was more frequently observed, and cellular distribution was more heterogeneous throughout the slide. When samples from healthy and diseased animals were considered together, a significantly greater percentage of neutrophils was seen on CP than on MSP slides (P<0.002). Cytospin preparations were considered of better quality in all individual comparisons. Cytospin preparation is advised in the evaluation of BALF with low total cell count. When only MSPs are evaluated, clinicians should be aware that differential neutrophil counts may underestimate the counts found on CP slides. [less ▲]

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See detailPretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium
Bartunek, Joseph; Croissant, J. D.; Wijns, William et al

in American Journal of Physiology - Heart and Circulatory Physiology (2007), 292(2), 1095-1104

The in vivo cardiac differentiation and functional effects of unmodified adult bone marrow mesenchymal stem cells (MSCs) after myocardial infarction (MI) is controversial. We postulated that ex vivo ... [more ▼]

The in vivo cardiac differentiation and functional effects of unmodified adult bone marrow mesenchymal stem cells (MSCs) after myocardial infarction (MI) is controversial. We postulated that ex vivo pretreatment of autologous MSCs using cardiomyogenic growth factors will lead to cardiomyogenic specification and will result in superior biological and functional effects on cardiac regeneration of chronically infarcted myocardium. We used a chronic dog MI model generated by ligation of the coronary artery (n = 30). Autologous dog bone marrow MSCs were isolated, culture expanded, and specified into a cardiac lineage by adding growth factors, including basic FGF, IGF-1, and bone morphogenetic protein-2. Dogs underwent cell injection > 8 wk after the infarction and were randomized into two groups. Group A dogs (n = 20) received MSCs specified with growth factors (147 +/- 96 x 10(6)), and group B (n = 10) received unmodified MSCs (168 +/- 24 x 10(6)). After the growth factor treatment, MSCs stained positive for the early muscle and cardiac markers desmin, antimyocyte enhancer factor-2, and Nkx2-5. In group A dogs, prespecified MSCs colocalized with troponin I and cardiac myosin. At 12 wk, group A dogs showed a significantly larger increase in regional wall thickening of the infarcted territory (from 22 +/- 8 to 32 +/- 6% in group A; P < 0.05 vs. baseline and group B, and from 19 +/- 7 to 21 +/- 7% in group B, respectively) and a decrease in the wall motion score index (from 1.60 +/- 0.05 to 1.35 +/- 0.03 in group A; P < 0.05 vs. baseline and group B, and from 1.58 +/- 0.07 vs. 1.56 +/- 0.08 in group B, respectively). The biological ex vivo cardiomyogenic specification of adult MSCs before their transplantation is feasible and appears to improve their in vivo cardiac differentiation as well as the functional recovery in a dog model of the chronically infarcted myocardium. [less ▲]

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See detailA randomised double blinded placebo controlled study of spironolactone as adjunct to conventional congestive heart failure treatment in dogs: clinical, biochemical and neurohormonal parameters
Schuller, S.; Van Israel; Van Belle, S. et al

in 16th ECVIM Meeting - Amsterdam - Nederland - Septembre 2006 (2006, September)

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See detailA randomised double blinded placebo controlled study of spironolactone as adjunct to conventional congestive heart failure treatment in dogs: electrocardiographic, radiographic, echocardiographic and survival analysis
Van Israel, N.; Schuller, S.; Van Belle, S. et al

in 16th ECVIM Meeting - Amsterdam - Nederland - Septembre 2006 (2006, September)

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See detailProcollagen type-III aminoterminal peptide in serum and bronchoalveolar lavage fluid in dogs with chronic bronchopneumopathies – preliminary results
Schuller, S.; Talavera, J.; Jespers, P. et al

in 15th ESVIM Meeting - Glasgow - Ecosse - Septembre 2005 (2005, September)

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See detailAnalytical, physiological and clinical validation of a radioimmunoassay for serum Procollagen Type-III aminoterminal peptide in the dog
Schuller, S.; Valentin, S.; Remy, B. et al

in 14th ESVIM Meeting - Barcelona - Espagne (2004, June)

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See detailEarly activation of cardiac and renal endothelin systems in experimental heart failure
Motte, S.; van Beneden, R.; Mottet, J. et al

in American Journal of Physiology - Heart and Circulatory Physiology (2003), 285(6), 2482-2491

We investigated the time course of the expression of cardiac and renal endothelin systems in tachycardia-induced heart failure in dogs. Eleven beagles underwent rapid pacing at a progressively increased ... [more ▼]

We investigated the time course of the expression of cardiac and renal endothelin systems in tachycardia-induced heart failure in dogs. Eleven beagles underwent rapid pacing at a progressively increased rate over a period of 5 wk, with a weekly clinical examination, echocardiography, measurement of circulating and urinary endothelin-1 (ET-1), and myocardial and renal tissue biopsies. Real-time quantitative PCR was used for determinations of tissue prepro-ET-1 (ppET-1), ET-1-converting enzyme (ECE-1), and ETA and ETB receptor mRNA. Cardiac and renal tissue ET-1 contents were evaluated by immunostaining and measured by radioimmunoassay at autopsy. Rapid pacing caused a progressive increase in end-systolic and end-diastolic ventricular volumes (P<0.05) from week 2 together with a decrease in ejection fraction and in mean velocity of circumferential shortening (P<0.05) from week 1. These changes were tightly correlated to myocardial ppET-1 and renal ETA receptor mRNA and less so to myocardial ECE-1 mRNA, and they occurred before any increase in plasma and urinary ET-1 (P<0.05 from week 4) and clinical signs of heart failure. Renal ppET-1 did not change. Both cardiac and renal ET-1 peptide contents were increased at autopsy. We conclude that tachycardia-induced heart failure in dogs is characterized by an early activation of the cardiac and renal tissue endothelin systems, which occurs before any changes in circulating and urinary ET-1 and is closely related to altered ventricular function. [less ▲]

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See detailRhinitis/Bronchopneumonia syndrome in Irish Wolfhounds.
Clercx, Cécile ULg; Reichler, I.; Peeters, Dominique ULg et al

in Journal of Veterinary Internal Medicine (2003), 17(6), 843-9

This study describes the clinical, immunologic, genetic, and pathologic features of Irish Wolfhounds with rhinitis/bronchopneumonia syndrome. The dogs examined were from Belgium, The Netherlands, UK ... [more ▼]

This study describes the clinical, immunologic, genetic, and pathologic features of Irish Wolfhounds with rhinitis/bronchopneumonia syndrome. The dogs examined were from Belgium, The Netherlands, UK, Canada, Germany, and Switzerland. Signs included transient to persistent mucoid or mucopurulent rhinorrhea, cough, and respiratory dyspnea. Radiographic, rhinoscopic, and bronchoscopic findings were variable. Analysis of ciliary ultrastructure was performed in 5 affected dogs, but no characteristic primary ciliary defects (primary ciliary dyskinesia) were detected. Serum and bronchoalveolar lavage fluid (BALF) concentrations of IgA, IgG, and IgM were determined in some affected dogs and clinically normal Irish Wolfhounds. Serum IgA concentration was below the reference range in 5 of 8 affected dogs tested, whereas BALF IgA concentration was above the normal range in 2 affected adult dogs. The CD4 to CD8 lymphocyte subset ratio (CD4:CD8) in peripheral blood was tested in 3 affected dogs and was within the normal range. BALF CD4:CD8 was tested in 1 affected dog and was higher than the normal range. Decreased neutrophil phagocytosis was observed in 1 of the 4 dogs tested. Analysis of pedigrees of the Belgian, Canadian, German, and Swiss dogs revealed common ancestry, suggesting a heritable syndrome. [less ▲]

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See detailUse of atropine to inhibit vagally mediated baroreceptor reflex in horses undergoing dobutamine stress test
Sandersen, Charlotte ULg; Detilleux, Johann ULg; Delguste, Catherine ULg et al

in Pflügers Archiv : European Journal of Physiology (2003), 446(5), 4

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See detailAn Immunologic investigation of canine eosinophilic bronchopneumopathy.
Clercx, Cécile ULg; Peeters, Dominique ULg; German, Alex et al

in Journal of Veterinary Internal Medicine (2002), 16

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