References of "MARTIN, Didier"
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See detailIs paralysing lumbar disc herniation a surgical emergency ?
DUBUISSON, Annie ULg; BORLON, Sarah ULg; NGUYEN KHAC, Minh-Tuan ULg et al

Conference (2011, March 26)

Detailed reference viewed: 53 (7 ULg)
See detailLa personne âgée en neurochirurgie
Martin, Didier ULg

Scientific conference (2011, March 23)

Detailed reference viewed: 25 (2 ULg)
See detailLa neuro-urologie
Martin, Didier ULg

Scientific conference (2011, January 12)

Detailed reference viewed: 15 (0 ULg)
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See detailPost-mortem assessment of rat spinal cord injury and white matter sparing using inversion recovery-supported proton density magnetic resonance imaging
Scholtes, Félix ULg; Theunissen, E.; Phan Ba, Remy ULg et al

in Spinal Cord : The Official Journal of the International Medical Society of Paraplegia (2011)

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See detail36-year-old man with sudden severe headache.
SIMONI, Paolo ULg; MEUNIER, Benoît ULg; Deprez, Manuel ULg et al

in Skeletal Radiology (2011), 40(10), 1361-21387-8

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See detailHuman glioblastoma-initiating cells invade specifically the subventricular zones and olfactory bulbs of mice after striatal injection.
Kroonen, Jérôme ULg; Nassen, Jessica ULg; Boulanger, Yves-Gauthier et al

in International Journal of Cancer = Journal International du Cancer (2011), 129(3), 574-585

This study reports the subsequent isolation of human glioblatoma cells able to initiate experimental brain tumors, specifically and repeatedly found in the subventricular zones and olfactory bulbs ... [more ▼]

This study reports the subsequent isolation of human glioblatoma cells able to initiate experimental brain tumors, specifically and repeatedly found in the subventricular zones and olfactory bulbs following xenograft in the caudate putamen of immunodeficient mice.In patients with glioblastoma multiforme, recurrence is the rule despite continuous advances in surgery, radiotherapy and chemotherapy. Within these malignant gliomas, glioblastoma stem cells or initiating cells have been recently described and they were shown to be specifically involved in experimental tumorigenesis. In this study, we show that some human glioblastoma cells injected into the striatum of immunodeficient nude mice exhibit a tropism for the subventricular zones. There and similarily to neurogenic stem cells, these subventricular glioblastoma cells were then able to migrate towards the olfactory bulbs. Finally, the glioblastoma cells isolated from the adult mouse subventricular zones and olfactory bulbs display high tumorigenicity when secondary injected in a new mouse brain. Together, these data suggest that neurogenic zones could be a reservoir for particular cancer-initiating cells. [less ▲]

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See detailComa and head traumatism
Martin, Didier ULg

Conference (2010, December 11)

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See detailDonnées chirurgicales récentes - adénomes hypophysaires
Martin, Didier ULg

Conference (2010, November 19)

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See detailTraumatisme médullaire : de la Clinique à la Recherche Fondamentale.
Martin, Didier ULg

Conference (2010, October 25)

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See detailLes céphalées qui inquiètent
Martin, Didier ULg

Scientific conference (2010, October 13)

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See detailThiamine Status in Humans and Content of Phosphorylated Thiamine Derivatives in Biopsies and Cultured Cells
Gangolf, Marjorie ULg; Czerniecki, Jan; Radermecker, Marc ULg et al

in PLoS ONE (2010), 5(10), 13616

Background Thiamine (vitamin B1) is an essential molecule for all life forms because thiamine diphosphate (ThDP) is an indispensable cofactor for oxidative energy metabolism. The less abundant thiamine ... [more ▼]

Background Thiamine (vitamin B1) is an essential molecule for all life forms because thiamine diphosphate (ThDP) is an indispensable cofactor for oxidative energy metabolism. The less abundant thiamine monophosphate (ThMP), thiamine triphosphate (ThTP) and adenosine thiamine triphosphate (AThTP), present in many organisms, may have still unidentified physiological functions. Diseases linked to thiamine deficiency (polyneuritis, Wernicke-Korsakoff syndrome) remain frequent among alcohol abusers and other risk populations. This is the first comprehensive study on the distribution of thiamine derivatives in human biopsies, body fluids and cell lines. Methodology and Principal Findings Thiamine derivatives were determined by HPLC. In human tissues, the total thiamine content is lower than in other animal species. ThDP is the major thiamine compound and tissue levels decrease at high age. In semen, ThDP content correlates with the concentration of spermatozoa but not with their motility. The proportion of ThTP is higher in humans than in rodents, probably because of a lower 25-kDa ThTPase activity. The expression and activity of this enzyme seems to correlate with the degree of cell differentiation. ThTP was present in nearly all brain and muscle samples and in ~60% of other tissue samples, in particular fetal tissue and cultured cells. A low ([ThTP]+[ThMP])/([Thiamine]+[ThMP]) ratio was found in cardiovascular tissues of patients with cardiac insufficiency. AThTP was detected only sporadically in adult tissues but was found more consistently in fetal tissues and cell lines. Conclusions and Significance The high sensitivity of humans to thiamine deficiency is probably linked to low circulating thiamine concentrations and low ThDP tissue contents. ThTP levels are relatively high in many human tissues, as a result of low expression of the 25-kDa ThTPase. Another novel finding is the presence of ThTP and AThTP in poorly differentiated fast-growing cells, suggesting a hitherto unsuspected link between these compounds and cell division or differentiation. [less ▲]

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See detailSpinal Cord Research on the Way to Translation
Martin, Didier ULg

Conference (2010, August 26)

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See detailPlace de la chimiothérapie dans le traitement des gliomes
Martin, Didier ULg

Scientific conference (2010, June 02)

Detailed reference viewed: 14 (3 ULg)
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See detailLa S-3D et réalité augmentée au service de la médecine et de la science
Audrit, Pierre; Martin, Didier ULg

Conference (2010, June 01)

Detailed reference viewed: 27 (3 ULg)
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See detailPostoperative sialadenitis with chronic brachial plexopathy
Reuter, Gilles; Racaru, Tudor ULg; Nguyen khac, Minh-Tuan et al

Poster (2010, March 20)

Detailed reference viewed: 14 (1 ULg)