References of "MAGIS, Delphine"
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See detailTherapeutic armamentarium in neurology: the birth of a new era
Belachew, Shibeshih ULg; Magis, Delphine ULg; Lievens, Isabelle ULg et al

in Revue Médicale de Liège (2007), 62(5-6), 432-448

The field of neurology was long infamous for a lack of therapeutic options. How many of you have once thought: "Neurologists don't cure the disease, they admire it". But those days have passed into ... [more ▼]

The field of neurology was long infamous for a lack of therapeutic options. How many of you have once thought: "Neurologists don't cure the disease, they admire it". But those days have passed into history, and the field is now vibrant with new treatments and hope even for patients with the worst neurodegenerative diseases. We summarized in the present review the latest major advances in therapeutic principles and practice for some of the most frequent chronic neurological disorders such as headaches, epilepsy, multiple sclerosis, dementias, Parkinson's disease, sleep/wake disturbances and peripheral neuropathies. We cannot cure or prevent, but we can now halt or control symptoms and disease progression to provide physical and psychological relief, and a better quality of life for patients who suffer from these otherwise devastating neurological conditions. [less ▲]

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See detailLong-term depression of trigeminal nociceptive evoked potentials by supraorbital 1Hz electrical stimulations is deficient in migraineurs but not in tension-type headache patients
Magis, Delphine ULg; Bolla, M.; De Pasqua, Victor ULg et al

in Cephalalgia : An International Journal of Headache (2006, November), 26(11), 1386

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See detailLong term follow-up study of occipital nerve stimulation (ONS) for refractory chronic cluster headache: drastic change from short term outcome
Magis, Delphine ULg; Remacle, J. M.; Schoenen, Jean ULg

in Cephalalgia : An International Journal of Headache (2006, November), 26(11), 1398

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See detailLes céphalées par abus d'antalgiques et d'anti-migraineux
Fumal, Arnaud ULg; Magis, Delphine ULg; Schoenen, Jean ULg

in Revue Médicale de Liège (2006), 61(4), 217-22

Medication overuse headache (MOH) insidiously evolves from episodic migraine or tension-type headache because of overconsumption of analgesics, ergotamine or triptans. It affects 1-2% of the general ... [more ▼]

Medication overuse headache (MOH) insidiously evolves from episodic migraine or tension-type headache because of overconsumption of analgesics, ergotamine or triptans. It affects 1-2% of the general population, but 15-20% of patients attending specialized headache centers. The precise neurobiologic mechanisms underlying this complication of episodic headaches are not well understood. Abnormalities of central monoaminergic systems have been suggested and substance dependence is more frequent in personal and family histories of affected subjects. In a recent FDG-PET study of 16 migraineurs with MOH before and after analgesics withdrawal we found a persistent hypometabolism of the medial orbitofrontal cortex, comparable to the one described after withdrawal in substance abuse. The orbitofrontal cortex plays a pivotal role in drive, decision-making and drug dependence. We postulate that its hypoactivity predisposes certain migraineurs to MOH and to relapse after withdrawal. There is no unique management strategy for these patients, but medication withdrawal is a prerequisite for the effectiveness of preventive treatments and headache improvement. [less ▲]

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See detailHerbal medicines and vitamins
Schoenen, Jean ULg; Magis, Delphine ULg

in Lipton, R. B.; Bigal, M. E. (Eds.) Migraines and Other headache disorders (2006)

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See detailProton MRS findings in migraine patients during visual stimulation
da Silva, H. M.; Magis, Delphine ULg; Balteau, Evelyne ULg et al

in Cephalalgia : An International Journal of Headache (2005, December), 25(12), 1196

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See detailOccipital nerve stimulation in refractory chronic cluster headache: a pilot study of efficacy and mechanisms in five patients
Magis, Delphine ULg; Allena, M.; Vandenheede, Michel et al

in Cephalalgia : An International Journal of Headache (2005, December), 25(12), 1197

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See detailOccipital nerve stimulation in refractory chronic cluster headache: a pilot study of efficacy and mechanisms in five patients.
MAGIS, Delphine ULg; Allena, Marta; Vandenheede, Michel et al

in Cephalalgia : An International Journal of Headache (2005, October), 25

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See detailLack of habituation of visual evoked gamma band oscillations in migraine patients between attacks
Coppola, G.; Ambrosini, A.; Di Clemente, L. et al

in Cephalalgia : An International Journal of Headache (2005, October), 25(10), 885

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See detailThe vestibulo-collic reflex is smaller and lacks habituation in migraine patients between attacks
Allena, M.; Magis, Delphine ULg; da Silva, H. M. et al

in Cephalalgia : An International Journal of Headache (2005, October), 25(10), 874-875

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See detailTrigeminal nociceptive evoked potentials (TNEP) in migraine
Magis, Delphine ULg; Allena, Marta; De Pasqua, Victor ULg et al

in Cephalalgia : An International Journal of Headache (2005, October), 25(10), 875

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See detailSearch for a correlation between MTHFR C677T polymorphism and efficacy of riboflavin in migraine prophylaxis
Magis, Delphine ULg; Allena, Marta; da Silva, Hilton Mariano et al

in Cephalalgia : An International Journal of Headache (2005, October), 25(10), 864

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See detailEffects of nitroglycerin on the nociception specific blink reflex
Di Clemente, Laura; Magis, Delphine ULg; Coppola, Gianluca et al

in Cephalalgia : An International Journal of Headache (2005, October), 25(10), 888

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See detailMTHFR C677T polymorphism and susceptibility to migraine with aura
Magis, Delphine ULg; Coppola, Gianluca; Allena, Marta et al

in Cephalalgia : An International Journal of Headache (2005, October), 25(10), 863-864

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See detailEfficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial
Sandor, P. S.; Di Clemente, L.; Coppola, G. et al

in Neurology (2005), 64(4), 713-715

Riboflavin, which improves energy metabolism similarly to coenzyme Q10 (CoQ10), is effective in migraine prophylaxis. We compared CoQ10 (3 x 100 mg/day) and placebo in 42 migraine patients in a double ... [more ▼]

Riboflavin, which improves energy metabolism similarly to coenzyme Q10 (CoQ10), is effective in migraine prophylaxis. We compared CoQ10 (3 x 100 mg/day) and placebo in 42 migraine patients in a double-blind, randomized, placebo-controlled trial. CoQ10 was superior to placebo for attack-frequency, headache-days and days-with-nausea in the third treatment month and well tolerated; 50%-responder-rate for attack frequency was 14.4% for placebo and 47.6% for CoQ10 (number-needed-to-treat: 3). CoQ10 is efficacious and well tolerated. [less ▲]

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See detailHeadache cases
MAGIS, Delphine ULg

Conference (2005)

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See detailA trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines.
Allena, Marta; Magis, Delphine ULg; Schoenen, Jean ULg

in Neurology (2005), 65(8), 1339-401339-40

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See detailNociceptive blink reflex and visual evoked potential habituations are correlated in migraine
Di Clemente, Laura; Coppola, Gianluca; Magis, Delphine ULg et al

in Headache (2005), 45(10, Nov-Dec), 1388-1393

BACKGROUND: Lack of habituation, as reported in migraine patients between attacks for evoked cortical responses, was also recently found for the nociceptive blink reflex (nBR) mediated by brainstem ... [more ▼]

BACKGROUND: Lack of habituation, as reported in migraine patients between attacks for evoked cortical responses, was also recently found for the nociceptive blink reflex (nBR) mediated by brainstem neurons. It is not known if both brain stem and cortical habituation deficits are correlated in the same patient, which would favor a common underlying mechanism. OBJECTIVE: To search for intraindividual correlations between habituation of pattern reversal-visual evoked potentials and that of the nociception-specific blink reflex in migraineurs and in healthy volunteers (HV). METHODS: We recorded 15 HV and 15 migraine without aura patients between attacks. Habituation for visual evoked potentials was measured by comparing the N1-P1 amplitude change (%) between the first and sixth block of 100 sequential averaged responses. Habituation for the nBR was defined as the percentage change of the R2 response area between the 1st and 10th block of five averaged EMG responses, elicited by stimulating the right side every 2 minutes for 32 minutes. We also calculated the slope of N1-P1 amplitude and R2 response area changes from the first to the last response and the correlation with attack frequency. RESULTS: A significant habituation deficit in both cortical and brain stem evoked activity characterized on average the group of migraineurs compared to controls. In migraine patients, but not in HV, we found a significant positive correlation between habituation of pattern reversal-visual evoked potentials and that of the nociception-specific blink reflex both for the degree of habituation between first and last blocks of averagings (r = 0.703; P = .003) and for the habituation slope (r = 0.751; P = .001). Moreover, nBR habituation was positively correlated with attack frequency (r = 0.548; P = .034). CONCLUSION: The positive correlation between visual evoked potential and nBR habituations is consistent with the idea that in migraine the same neurobiological dysfunction might be responsible for the habituation deficit both in cortex and brain stem. As nBR habituation increases with attack frequency, its interictal deficit is unlikely to be due to trigeminal sensitization. [less ▲]

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