References of "Lins, Laurence"
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See detailModeling of the cyclic lipodepsipeptide Pseudodesmin A self-assembly through molecular dynamic simulations
Crowet, Jean-Marc ULg; Sinnaeve, Davy; Fehér, Kristina et al

Poster (2016, April)

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See detailRe-visiting plant plasma membrane lipids in tobacco: a focus on sphingolipids
Cacas, Jean Luc; Buré, Corinne; Grosjean, Kevin et al

in Plant Physiology (2016), 170

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See detailInteractions of sugar-based bolaamphiphiles with biomimetic systems of plasma membranes
Nasir, Mehmet Nail ULg; Crowet, Jean-Marc ULg; Lins, Laurence ULg et al

in Biochimie (2016), 130

Glycolipids constitute a class of molecules with various biological activities. Among them, sugar-based bolaamphiphiles characterized by their biocompatibility, biodegradability and lower toxicity, became ... [more ▼]

Glycolipids constitute a class of molecules with various biological activities. Among them, sugar-based bolaamphiphiles characterized by their biocompatibility, biodegradability and lower toxicity, became interesting for the development of efficient and low cost lipid-based drug delivery systems. Their activity seems to be closely related to their interactions with the lipid components of the plasma membrane of target cells. Despite many works devoted to the chemical synthesis and characterization of sugar-based bolaamphiphiles, their interactions with plasma membrane have not been completely elucidated. In this work, two sugar-based bolaamphiphiles differing only at the level of their sugar residues were chemically synthetized. Their interactions with membranes have been investigated using model membranes containing or not sterol and with in silico approaches. Our findings indicate that the nature of sugar residues has no significant influence for their membrane interacting properties, while the presence of sterol attenuates the interactions of both bolaamphiphiles with the membrane systems. The understanding of this distinct behavior of bolaamphiphiles towards sterol-containing membrane systems could be useful for their applications as drug delivery systems. [less ▲]

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See detailNegatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY*
Sautrey, Guillaume; El Khoury, Micheline; Dos Giros, Andrea et al

in Journal of Biological Chemistry (2016), 291(26), 13864-13874

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See detailSimulation par dynamique moléculaire de membranes lipidiques complexes
Crowet, Jean-Marc ULg; Dauchez, Manuel; Lins, Laurence ULg

Scientific conference (2015, November 25)

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See detailModeling of the cyclic lipodepsipeptide Pseudodesmin A self- assembly through molecular dynamic simulations
Crowet, Jean-Marc ULg; Sinnaeve, Davy; Fehér, Kristina et al

Poster (2015, October)

Detailed reference viewed: 9 (0 ULg)