Image du mois. Fibrodysplasie musculaire de l'artère rénale.

in Revue Médicale de Liège (2004), 59(11), 624-5

Angioplastie percutanee coronaire chez le patient diabetique Partie 1 : echecs relatifs lies a la restenose apres angioplastie simple.

in Revue Médicale de Liège (2004), 59(10), 584-90

Diabetes mellitus, essentially type 2 diabetes, is markedly associated with a high risk of cardiovascular diseases, especially coronary artery disease (CAD). Revascularization techniques, first coronary ... [more ▼]

Diabetes mellitus, essentially type 2 diabetes, is markedly associated with a high risk of cardiovascular diseases, especially coronary artery disease (CAD). Revascularization techniques, first coronary artery bypass graft (CABG) and second percutaneous transluminal coronary angioplasty (PTCA), have drastically changed the management of patients with CAD. Unfortunately, overall results of such revascularization procedures are less impressive in diabetic patients than in nondiabetic subjects, because of a worse vascular bed due to a more diffuse disease including small vessels. The diabetic population is indeed characterized by higher rates of both post-CABG thrombosis and post-PTCA restenosis, as compared to the corresponding rates observed in a nondiabetic population. Such vascular complications result in a higher incidence of coronary events leading to greater morbidity and mortality in both the short (weeks-months) and long (years) term. The bad quality of blood glucose control appears to play a crucial role in the risk of restenosis and further complications. The use of endovascular stents, especially new drug-eluting stents reducing the risk of restenosis, may represent a new opportunity for the management of a high-risk population such as diabetic patients. [less ▲]

Angioplastie percutanee coronaire chez le patient diabetique. Partie 3: Nouvelles perspectives apportees par les stents enrobes.

in Revue Médicale de Liège (2004), 59(12), 711-6

Coronary revascularization procedures are associated with less favourable outcomes in diabetic patients as compared to non-diabetic individuals. Especially, percutaneous coronary angioplasty (PTCA) is ... [more ▼]

Coronary revascularization procedures are associated with less favourable outcomes in diabetic patients as compared to non-diabetic individuals. Especially, percutaneous coronary angioplasty (PTCA) is associated with a high level of restenosis and recurrent cardiac morbidity and mortality. In diabetic patients, PTCA should ideally be combined with stents. Bare-metal stents reduce by almost half the risk of restenosis, but this favourable effect decreases with the vessel calibre, a common finding in diabetic patients. Drug-eluting stents containing pharmacological agents that can reduce the risk of restenosis (sirolimus, paclitaxel) provide better angiographic results, including in small coronary arteries, and this effect has been shown to be accompanied by significant reduction of both morbidity and mortality. Such preliminary results obtained in the general population (including around 20% of diabetic subjects) deserve further confirmation in a large clinical trial specifically devoted to diabetic patients. Drug-eluting stents may represent a major advance in the management of diabetic patients with coronary heart disease in the near future. [less ▲]

Periodontal condition in Belgian patients with acute or chronic heart disease

in Journal of Dental Research (2002, December), 81(Sp. Iss. B), 240-240

Apports des troponines au diagnostic et traitement des cardiopathies ischémiques

Conference (2002, June 26)

Relationship between lipoprotein (a) and cardiac troponins in PTCA patients

in Acta Clinica Belgica (2001), 56

Association between lipoprotein (A) and cardiac troponins in PTCA patients

in Clinical Chemistry & Laboratory Medicine (2001), 39(suppl), 278

Prognostic significance of increased baseline plasma troponin I levels in PTCA patients

Poster (2000, April)

Prognostic significance of increased baseline plasma troponin I levels in PTCA patients

in Heart (2000), 83(suppl. II), 24

Inflammatory response to coronary angioplasty: determinants and clinical applications

Poster (1999, December 01)