Evolution of serum cardiac troponin-I and CK-MB during and after coronary bypass surgeryChapelle, Jean-Paul ; ; Faymonville, Marie-Elisabeth et alPoster (1995, May) Detailed reference viewed: 11 (0 ULg) Opioids in intensive careLamy, Maurice ; Joris, Jean ; Damas, Pierre et alin Lawin, P.; Von Loewenich, V.; Schuster, H.-P. (Eds.) et al Intensivmedizin notfallmedizin anästhesiologie (1995) Detailed reference viewed: 14 (2 ULg) Les morphinomimétiques en réanimationLamy, Maurice ; Joris, Jean ; Damas, Pierre et alin Réan urg (1993), 2(4bis), 488-494 Detailed reference viewed: 23 (6 ULg) Myeloperoxidase and elastase as markers of leukocyte activation during cardiopulmonary bypass in humansFaymonville, Marie ; Pincemail, Joël ; et alin Journal of Thoracic and Cardiovascular Surgery (The) (1991), 102 Detailed reference viewed: 36 (8 ULg) Plasma renin activity and urine beta 2-microglobulin during and after cardiopulmonary bypass: pulsatile vs non-pulsatile perfusionCanivet, Jean-Luc ; Larbuisson, Robert ; Damas, Pierre et alin European Heart Journal (1990), 11(12), 1079-1082 Fourteen patients with normal preoperative renal function underwent aortocoronary bypass graft using cardiopulmonary bypass (CPB) with pulsatile (P;n = 7) or non pulsatile (NP;n = 7) perfusion. In the two ... [more ▼] Fourteen patients with normal preoperative renal function underwent aortocoronary bypass graft using cardiopulmonary bypass (CPB) with pulsatile (P;n = 7) or non pulsatile (NP;n = 7) perfusion. In the two groups prebypass values of plasma renin activity (PRA) and urine beta 2-microglobulin (beta 2-M) were within normal limits. PRA increased significantly during CPB and the first 6 h after CPB only in the non-pulsatile group. In both groups, the urine beta 2-M level increased significantly during and after CPB; however, there was no significant difference in urine beta 2-M levels between the two groups. Also, the amount of beta 2-M excreted in urines per unit of time increased significantly in both groups during and after CPB; there was no significant difference between the two groups. [less ▲] Detailed reference viewed: 20 (1 ULg) Fluid management and plasma renin activity in organ donorsCanivet, Jean-Luc ; Damas, Pierre ; Hans, Pol et alin Transplant International : Official Journal of the European Society for Organ Transplantation (1989), 2(3), 129-132 Fluid management and assessment of organ perfusion in organ donors with hypotonic polyuria remain poorly investigated problems. In our protocol, urinary losses (565 +/- 202 ml/h) were replaced volume for ... [more ▼] Fluid management and assessment of organ perfusion in organ donors with hypotonic polyuria remain poorly investigated problems. In our protocol, urinary losses (565 +/- 202 ml/h) were replaced volume for volume by 3.3% dextrose/0.3% natrium chloride solution (Baxter) with 20 mmol/l potassium chloride. Concentrated red blood cells were administered to maintain hematocrit at about 30%, and volume expansion (central venous pressure above 6 mmHg) was obtained by gelatin (haemaccel) infusion. In all donors (n = 9), plasma electrolytes remained within normal limits despite hypotonic polyuria. Suppression of initial plasma renin activity (PRA: 9.7 +/- 3.6 ng/ml per hour) was obtained by subacute volume expansion. In eight donors the hemodynamic status improved, dopamine administration, when used, was discontinued, and PRA decreased (2.3 +/- 0.7 ng/ml per hour; P less than 0.05). The only donor who failed to respond to fluid therapy had increased PRA (24.2 ng/ml per hour). During fluid challenge, an inverse relationship was demonstrated between mean arterial pressure and PRA in all nine donors (r = -0.61; P less than 0.001), while there were no significant changes in blood urea. creatinine, or urine output. It is concluded that in organ donors, proper maintenance of the hemodynamic status and suppression of the renin stress response may be obtained by an adequate fluid management, involving both qualitative restoration and expansion of intravascular volume. [less ▲] Detailed reference viewed: 20 (0 ULg) Interest of Face Mask--Cpap in One Case of Severe Accidental HypothermiaCanivet, Jean-Luc ; Larbuisson, Robert ; Lamy, Maurice ![]() in Acta Anaesthesiologica Belgica (1989), 40(4), 281-3 one case of severe accidental hypothermia; rectal temperature was 25 degrees C. Hypoxemia unmodified by 100 O2 inhalation in an ordinary face-mask was easily corrected using a face-mask CPAP; a ... [more ▼] one case of severe accidental hypothermia; rectal temperature was 25 degrees C. Hypoxemia unmodified by 100 O2 inhalation in an ordinary face-mask was easily corrected using a face-mask CPAP; a ventilation-perfusion mismatching could be implicated in the cold induced hypoxemia. Active rewarming (1.5 degrees C/h) was pursued from 25 to 37 degrees C, using non aggressive methods: warming blankets and a Bennett heated humidifier inserted in the CPAP system. Even in severe hypothermia successful results may be obtained without resort to sophisticated methods. [less ▲] Detailed reference viewed: 15 (0 ULg) Le prélèvement multiorganes: maillon essentiel d'une chaîne de solidaritéDefraigne, Jean-Olivier ; Canivet, Jean-Luc ; Bonnet, Pierre et alin Revue Médicale de Liège (1989), XLIII(4), 138-148 Detailed reference viewed: 9 (0 ULg) Inhibiteurs de la monoamine oxydase et anesthésie; Larbuisson, Robert ; Lamy, Maurice ![]() in Revue Médicale de Liège (1988), XLIII(2), 51-56 Detailed reference viewed: 13 (2 ULg) Evolution of serum creatine kinase (CK)-MB isoforms during and after coronary surgeryChapelle, Jean-Paul ; ; Faymonville, Marie-Elisabeth et alPoster (1988) Detailed reference viewed: 6 (0 ULg) Un cas de maladie métabolique hépatique de Wilson traité radicalement par une transplantation de foieHonore, Pierre ; Meurisse, Michel ; et alin Revue Médicale de Liège (1988), 43 Les auteurs présentent un cas de cirrhose, développée sur une maladie de Wilson. Une greffe orthotopique de foie a été réalisée avec succès. Ils reprennent les principales indications de cette technique ... [more ▼] Les auteurs présentent un cas de cirrhose, développée sur une maladie de Wilson. Une greffe orthotopique de foie a été réalisée avec succès. Ils reprennent les principales indications de cette technique et décrivent également les manifestations de la maladie de Wilson en général et son diagnostic. [less ▲] Detailed reference viewed: 62 (2 ULg) Evolution of serum creatine kinase (CK)-MB isoforms during and after coronary surgeryChapelle, Jean-Paul ; ; Faymonville, Marie-Elisabeth et alin European Heart Journal Supplements : Journal of the European Society of Cardiology (1988), 9(suppl.1), 244 Detailed reference viewed: 9 (0 ULg) Greffe combinée rein-pancréas dans la néphropathie diabétique terminale. Rapport de la première transplantation à l'ULg.RevueMeurisse, Michel ; ; Honoré, Pierre et alin Revue Médicale de Liège (1986), XLI(21), 855-863 Detailed reference viewed: 26 (1 ULg) Prostaglandin E2, prostacyclin, and thromboxane changes during nonpulsatile cardiopulmonary bypass in humans.Faymonville, Marie ; Deby, Ginette ; Larbuisson, Robert et alin Journal of Thoracic and Cardiovascular Surgery (The) (1986), 91(6), 858-66 To study the effect of lung bypass on the production of prostaglandin E2, prostacyclin, and thromboxane A2, we measured simultaneously arterial and venous plasma concentrations of prostaglandin E2, 6-keto ... [more ▼] To study the effect of lung bypass on the production of prostaglandin E2, prostacyclin, and thromboxane A2, we measured simultaneously arterial and venous plasma concentrations of prostaglandin E2, 6-keto-prostaglandin F1 alpha (stable metabolite of prostacyclin), and thromboxane B2 (stable metabolite of thromboxane A2) before, during, and after cardiopulmonary bypass. Seventeen patients (age range 46 to 69 years) undergoing aorta-coronary bypass grafts were investigated. The prostaglandin E2 production rose sharply immediately after the onset of bypass (baseline: 9.7 +/- 2.9 pg/ml to 85 +/- 16.6 pg/ml in venous and 87 +/- 12 pg/ml in arterial plasma, p less than 0.03) and rapidly decreased after pulmonary reperfusion (53 +/- 6.4 and 57 +/- 20 pg/ml, respectively, in venous and arterial plasma at the end of bypass). The increase in prostaglandin E2 was influenced by the heart-lung machine itself (as demonstrated by a closed "bypass" circuit) and by lung bypass. Pulmonary metabolism of prostaglandin E2 was maintained after bypass. The prostacyclin production rose significantly at the beginning of bypass (154 +/- 26 pg/ml venous prebypass level to 361 +/- 94 pg/ml after aortic clamping, p less than 0.03). Prostacyclin decreased progressively during rewarming of the patient, pulmonary reperfusion, and discontinuation of bypass. When prostacyclin decreased, thromboxane B2 production rose significantly and reached peak arterial levels when the lungs were reperfused (112 +/- 33 pg/ml prebypass levels to 402 +/- 101 pg/ml, p less than 0.01). Except for prostaglandin E2, there were no significant differences between arterial and venous plasma levels of these substances. The same prostanoids were also measured in five patients undergoing major orthopedic operations, and no significant changes in prostanoids were observed. Our data demonstrate significant production of prostaglandin E2 in the systemic circulation during cardiopulmonary bypass in humans. They further indicate that lung bypass disturbs the plasma prostaglandin/thromboxane balance. [less ▲] Detailed reference viewed: 26 (2 ULg) The value of serum CK-MB and myoglobin measurements for assessing perioperative myocardial infarction after cardiac surgery.Chapelle, Jean-Paul ; ; Larbuisson, Robert et alin Scandinavian Journal of Clinical & Laboratory Investigation (1986), 46(6), 519-26 In 41 patients who underwent coronary bypass surgery, creatine kinase (CK)-MB mass concentration was repeatedly measured in serum during and after the intervention using a new two-site immunoenzymetric ... [more ▼] In 41 patients who underwent coronary bypass surgery, creatine kinase (CK)-MB mass concentration was repeatedly measured in serum during and after the intervention using a new two-site immunoenzymetric assay (IEMA). Serum CK-MB activity was determined with the use of four different techniques: immunoinhibition, immunoinhibition-immunoprecipitation, column chromatography and electrophoresis. Myoglobin (Mb) was also measured in each specimen by radioimmunoassay. In the 33 patients who followed a completely uneventful postoperative course, the cumulated CK-MB release was, on the average, 12.2-fold less than after acute myocardial infarction. The CK-MB peak concentrations using the IEMA were 33 +/- 3 micrograms/l (X +/- SEM) and occurred 6.4 +/- 0.5 h after the intervention was started; CK-MB levels had decreased to 2.9 +/- 0.4 micrograms/l at the end of the first postoperative day. The evolution of the CK-MB concentration was parallel to that of the enzyme activity. The serum Mb maximum concentrations (518 +/- 39 micrograms/l) were reached after 3.3 +/- 0.1 h. The other eight patients developed perioperative myocardial infarction (PMI); in this group, the cumulated CK-MB release was higher, and the serum CK-MB postoperative curves were of three different types. The patients with delayed CK-MB peaks (type I pattern) or sustained elevations (type III) of this isoenzyme also showed increased serum Mb levels at the end of the first postoperative day. The PMI patients with early (10 h) CK-MB elevations (type II) did not demonstrate abnormal serum Mb levels.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲] Detailed reference viewed: 15 (0 ULg) Improved detection of perioperative myocardial infarction after cardiac surgery using CK-MB mass measurementsChapelle, Jean-Paul ; ; Larbuisson, Robert et alConference (1985, November) Detailed reference viewed: 4 (0 ULg) Activite serique de l'enzyme de conversion de l'angiotensine pendant la circulation extracorporelle chez l'homme.Faymonville, Marie-Elisabeth ; Larbuisson, Robert ; Radermecker, Maurice et alin Comptes Rendus des Séances de la Société de Biologie et de ses Filiales (1983), 177(2), 252-8 Serum activity of angiotensin converting enzyme (ACE) were measured during extra-corporeal circulation in five patients undergoing aorto-coronary bypass surgery. We observed a significant decrease of ... [more ▼] Serum activity of angiotensin converting enzyme (ACE) were measured during extra-corporeal circulation in five patients undergoing aorto-coronary bypass surgery. We observed a significant decrease of serum ACE levels in the absence of pulmonary circulation, suggesting that in man the lungs were the major source of circulating ACE. An effective extra-pulmonary liberation of ACE could take place during cardiopulmonary bypass. The levels of serum ACE increased with pulmonary recirculation, but preoperative levels were not reached 24 h later. [less ▲] Detailed reference viewed: 16 (0 ULg) Quelques facteurs d'augmentation du taux de thromboxane et de prostacycline chez l'hommeDeby, Ginette ; ; Larbuisson, Robert et alin Bulletin de l'Académie Royale de Médecine de Belgique (1983) Detailed reference viewed: 30 (1 ULg) Release of thromboxane B2 during adult respiratory distress syndrome and its inhibition by non steroidal anti-inflammatory substances in manDeby, Ginette ; ; et alin Archives Internationales de Pharmacodynamie et de Thérapie (1982), 259 Detailed reference viewed: 6 (2 ULg) Effet de drogues utilisées en anesthésie sur l'index de viabilité de l'endocarde (EVR ou "endocardial viability ratio") en chirurgie cardiaqueLarbuisson, Robert ; ; et alin Annales de l'Anesthésiologie Française (1979), 20(5), 469-474 Detailed reference viewed: 24 (0 ULg) |
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