References of "Kulbertus, Henri"
     in
Bookmark and Share    
Peer Reviewed
See detailEffect of the haptoglobin phenotype on the size of a myocardial infarct.
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Smeets, J P et al

in New England Journal of Medicine [=NEJM] (1982), 307(8), 457-63

We investigated the relation between haptoglobin (Hp) phenotypes and serum levels of various biochemical markers after myocardial infarction in 496 patients. In 122 subjects selected on the basis of short ... [more ▼]

We investigated the relation between haptoglobin (Hp) phenotypes and serum levels of various biochemical markers after myocardial infarction in 496 patients. In 122 subjects selected on the basis of short delays until hospitalization, patients with Hp 2-2 had higher cumulated creatine kinase activity than patients with Hp 1-1, or Hp 2-1 (P less than 0.05), as well as higher myoglobin concentrations (P less than 0.02) 12 to 28 hours after admission. Comparison of serum enzyme activities in the remaining 374 patients confirmed that Hp 2-2 patients had significantly higher total creatine kinase, creatine kinase isoenzyme MB fraction, aspartate aminotransferase, and lactate dehydrogenase peak levels. Complications of left ventricular failure were more frequent in these patients (P = 0.05). Our results suggest that Hp 2-2 patients have more severe myocardial infarctions than Hp 1-1 and Hp 2-1 patients, However, no difference in the distribution of haptoglobin phenotype was found between patients who had a myocardial infarction and healthy subjects, indicating that Hp 2-2 does not predispose to the occurrence of infarction. [less ▲]

Detailed reference viewed: 6 (2 ULg)
Peer Reviewed
See detailCritical evaluation of serum uric acid levels in acute myocardial infarction.
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Boland, Jean et al

in Clinica Chimica Acta (1982), 121(2), 147-157

Serial measurements of serum uric acid were performed on patients suffering from acute myocardial infarction. Nearly 80 percent of the cases demonstrated a fall in uric acid concentrations during the ... [more ▼]

Serial measurements of serum uric acid were performed on patients suffering from acute myocardial infarction. Nearly 80 percent of the cases demonstrated a fall in uric acid concentrations during the first two days of hospitalization and a subsequent return to initial levels within six to eight days. There was a relationship between the decrease in uric acid levels and the serum lactate dehydrogenase activity. No evidence could be found that male patients were hyperuricemic as compared to control subjects. However, female patients between 40 and 60 years of age demonstrated significantly higher uric acid levels than healthy women of corresponding ages, even after adjustment for diuretic use. [less ▲]

Detailed reference viewed: 24 (2 ULg)
See detailQuantitative aspects of serum myoglobin changes in acute myocardial infarction
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Smeets, J. P. et al

Poster (1981, September)

Detailed reference viewed: 2 (0 ULg)
See detailEvaluation of risk using serial laboratory data in acute myocardial infarction
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Heusghem, C. et al

Conference (1981, September)

Detailed reference viewed: 10 (0 ULg)
Peer Reviewed
See detailThe prognostic significance of serum alpha 1-acid glycoprotein changes in acute myocardial infarction.
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Smeets, J. P. et al

in Clinica Chimica Acta (1981), 115(2), 199-209

Serum alpha 1-acid glycoprotein and haptoglobin concentrations were evaluated in 151 patients with acute myocardial infarction (MI) during the first ten days of hospitalization. Maximum glycoprotein ... [more ▼]

Serum alpha 1-acid glycoprotein and haptoglobin concentrations were evaluated in 151 patients with acute myocardial infarction (MI) during the first ten days of hospitalization. Maximum glycoprotein concentrations were found to be related to myoglobin and enzyme peak levels. Glycoprotein levels recorded upon patients' admission did not vary for acute phase survivors and early deaths (15 patients), but the latter demonstrated significantly higher alpha 1-acid glycoprotein levels (p less than 0.05) on day 1. The maximum glycoprotein concentrations were, however, reached too long after the onset of acute MI to be of interest for short-term prognosis. Comparison of the evolution of the two glycoproteins investigated in late deaths (10 patients) and in 6-month survivors indicated increased alpha 1-acid glycoprotein levels in non-survivors, with a maximum discrimination occurring on day 8 (p less than 0.001). Haptoglobin was not significantly different in the two groups and even demonstrated lower concentrations from day 4 to day 10 in non-survivors. The decrease of haptoglobin levels in patients with hepatic dysfunction could explain the divergent results given by the serum concentrations of the two glycoproteins to predict mortality. We show in this study that alpha 1-acid glycoprotein measured at the end of hospitalization can give relevant prognostic information for the 6-month period following acute MI. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Peer Reviewed
See detailQuantitative aspect of serum myoglobin changes in acute myocardial infarction
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Smeets, J. P. et al

in European Heart Journal (1981), 2(A), 213

Detailed reference viewed: 9 (1 ULg)
Peer Reviewed
See detailEarly assessment of risk in patients with acute myocardial infarction.
Chapelle, Jean-Paul ULg; Albert, A.; Smeets, J. P. et al

in European Heart Journal (1981), 2(3), 187-96

Detailed reference viewed: 9 (0 ULg)
See detailPlasma alpha-1-acid glycoprotein and haptoglobin changes in acute myocardial infarction: relationship to early mortality
Chapelle, Jean-Paul ULg; Smeets, J. P.; Sourdeau, L. et al

Poster (1980, November)

Detailed reference viewed: 7 (0 ULg)
See detailInfarct size estimates from myocardial thallium and phosphate scans. prognostic implications
Rigo, P.; Betz-Rigo, Ch; Smeets, J. P. et al

Poster (1980, March)

Detailed reference viewed: 3 (0 ULg)
Peer Reviewed
See detailPredictive value of serum enzyme determinations in acute myocardial infarction.
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Heusghem, C. et al

in Clinica Chimica Acta (1980), 106(1), 29-38

Detailed reference viewed: 12 (3 ULg)
Peer Reviewed
See detailStrategie nouvelle en matiere d'interpretation des donnees en biologie medicale.
Heusghem, C.; Albert, Adelin ULg; Plomteux, Guy ULg et al

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1979), 134(11), 659-77

Detailed reference viewed: 26 (1 ULg)
See detailBiochemical approach to the Prognosis of acute myocardial infarction
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Heusghem, C. et al

Poster (1978, June 25)

Detailed reference viewed: 6 (0 ULg)
See detailMultivariate analysis of biochemical data in acute myocardial infarction
Heusghem, C.; Chapelle, Jean-Paul ULg; Albert, Adelin ULg et al

Poster (1978)

Detailed reference viewed: 4 (1 ULg)
See detailEléments de pronostic dans l'infarctus du myocarde au stade aigu
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Demoulin, J. C. et al

Conference (1977, October 08)

Detailed reference viewed: 11 (2 ULg)