References of "Kulbertus, Henri"
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See detailHemodynamic profile of patients with acute myocardial infarction at risk of infarct expansion.
Pierard, Luc ULg; Albert, Adelin ULg; Gilis, F et al

in American Journal of Cardiology (1987), 60(1), 5-9

To identify patients at risk of cardiac expansion during hospital stay for a first acute myocardial infarction (AMI), 41 patients underwent right-sided cardiac catheterization soon after admission and ... [more ▼]

To identify patients at risk of cardiac expansion during hospital stay for a first acute myocardial infarction (AMI), 41 patients underwent right-sided cardiac catheterization soon after admission and serial 2-dimensional echocardiography on days 1, 3 or 4 and between days 7 and 10. Infarct expansion was recognized by echocardiography in 11 patients (27%), most often on the second recording (day 3 or 4). Age, sex, time from onset of pain to catheterization, peak levels of creatine kinase and creatine kinase-MB isoenzyme, heart rate, mean pulmonary artery wedge pressure and left ventricular stroke work index were similar in the 2 groups. Patients in whom infarct expansion developed had a higher incidence of previous systemic hypertension (73% vs 27%, p less than 0.01) and anterior AMI (91% vs 30%, p less than 0.001) and a higher mortality rate at 1 year (73 vs 7%, p less than 0.001) than those who did not. They also had higher systolic (139 +/- 24 vs 126 +/- 18 mm Hg, p less than 0.05) and diastolic (91 +/- 14 vs 75 +/- 13 mm Hg, p less than 0.001) arterial pressures, lower stroke volume index (31 +/- 10 vs 40 +/- 10 ml/m2, p less than 0.01) and much higher systemic vascular resistance (SVR) values (1,713 +/- 380 vs 1,253 +/- 264 dynes s cm-5, p less than 0.0001). In the subgroups of patients with anterior AMI, differences were significant for diastolic arterial pressure, stroke volume index, SVR and mortality.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailShort and long-term prognosis of small acute myocardial infarction : a natural history study
Dubois, Christophe ULg; Pierard, Luc ULg; Albert, Adelin ULg et al

in European Heart Journal Supplements : Journal of the European Society of Cardiology (1987), 8(suppl.2), 110

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See detailEarly pronostic index and late exercise test compared in survivors from acute myocardial infarction
Chapelle, Jean-Paul ULg; Smeets, J. P.; El Allaf, M. et al

in European Heart Journal Supplements : Journal of the European Society of Cardiology (1987), 8(suppl.2), 11

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See detailThrombolysis in anterior myocardial infarction: effect on regional viability studied with positon emission tomography
de landsheere, C. M.; Raets, D.; Pierard, Luc ULg et al

in Circulation (1987), 76(suppl.IV), 5

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See detailIncidence and significance of pericardial effusion in acute myocardial infarction as determined by two-dimensional echocardiography
PIERARD, Luc ULg; Albert, Adelin ULg; Henrard, L. et al

in Journal of the American College of Cardiology (1986), 8

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See detailComplementary role of thallium-201 scintigraphy to predischarge exercise electrocardiography for patients stratification after a first myocardial infarction.
Legrand, Victor ULg; Albert, Adelin ULg; Rigo, Pierre ULg et al

in European Heart Journal (1986), 7(8), 644-53726

The value of a predischarge exercise test combined with thallium-201 myocardial scintigraphy in detecting patients with severe multivessel disease (MVD) was studied in 58 consecutive patients discharged ... [more ▼]

The value of a predischarge exercise test combined with thallium-201 myocardial scintigraphy in detecting patients with severe multivessel disease (MVD) was studied in 58 consecutive patients discharged after a first acute myocardial infarction. Twelve electrocardiographic, clinical and scintigraphic variables were analysed. Angiography at one month revealed MVD (greater than 70% narrowing in vessels unrelated to infarction) in 26 patients (45%). ST segment depression of 1mm or greater, thallium defects in multiple vascular distributions (MVTL), and reversible thallium defects in a vascular distribution different from the infarct related vessel predicted patients at risk for MVD (predictive value respectively of 68%, 65% and 75%). The other variables were not significantly associated with the presence of MVD. Only ST segment depression and thallium defects in multiple vascular distributions emerged as independent predictors of MVD. Their combination yielded a 77% sensitivity and a 59% specificity for MVD. Combination of thallium imaging with the predischarge exercise ECG significantly improved the stratification provided by the exercise test alone (P less than 0.05). A positive thallium scan (MVTl defects) associated with a positive ECG (ST depression) carried a risk for MVD of 80% in the population studied. When both tests were negative, MVD was infrequent (risk 22%). Because improvement in the stratification of patients is not as clear as expected from studies performed at a later stage, it appears that exercise thallium scintigraphy at a submaximal level one or two weeks after infarction does not provide optimal information. Predischarge exercise thallium-201 scintigraphy, however, is superior to an exercise tolerance test alone in separating patients into those with high and low risk of MVD. [less ▲]

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See detailSerum creatine kinase isoenzyme MB concentration after endomyocardial biopsy.
Chapelle, Jean-Paul ULg; El Allaf, Dia ULg; el Allaf, M. et al

in Clinica Chimica Acta (1986), 157(1), 55-63

Serum total creatine kinase (CK), CK-MB and myoglobin (Mb) were serially determined in 17 patients who underwent endomyocardial biopsy. Mean total CK levels increased from 36 +/- 27 U/l 30 min before ... [more ▼]

Serum total creatine kinase (CK), CK-MB and myoglobin (Mb) were serially determined in 17 patients who underwent endomyocardial biopsy. Mean total CK levels increased from 36 +/- 27 U/l 30 min before biopsy to a maximum of 112 +/- 77 U/l 8 h following the procedure (p less than 0.05). Similarly, Mb concentrations rose from 57 +/- 55 micrograms/l to 119 +/- 57 micrograms/l 30 min after biopsy (p less than 0.05). Normalization of total CK and Mb levels occurred within 16 and 8 h, respectively. A new immunoenzymetric assay (IEMA) was used to measure the mass concentration of the CK-MB molecule. The initial CK-MB levels were 0.2 +/- 0.4 microgram/l; a small but significant elevation was recorded as early as 2 h after biopsy (1.6 +/- 1.5 micrograms/l, p less than 0.05). CK-MB returned to initial concentration 16 h after the beginning of the procedure. Comparison with the maximum CK-MB levels recorded in 16 myocardial infarction patients (258 +/- 172 micrograms/l, range 90-680 micrograms/l) indicated that the modest increase of CK-MB level detected after biopsy probably reflects a limited endomyocardium lesion at the sampling site, excluding any significant myocardial damage. Total CK and Mb, which showed more pronounced elevations than CK-MB, are likely to originate from other sources than the myocardium. [less ▲]

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See detailPatterns of total CK, CK-MB and myoglobin release following endomyocardial biopsy
Chapelle, Jean-Paul ULg; El Allaf, Dia ULg; El Allaf, M. et al

Poster (1985, September)

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See detailContribution de la chimie clinique au diagnostic et au pronostic de l'infarctus du myocarde.
Heusghem, C.; Chapelle, Jean-Paul ULg; Kulbertus, Henri ULg

in Bulletin de l'Académie Nationale de Médecine (1985), 169(7), 1097-107

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See detailOn the interpretation of serial laboratory measurements in acute myocardial infarction.
Albert, Adelin ULg; Harris, E. K.; CHAPELLE, Jean-Paul ULg et al

in Clinical Chemistry (1984), 30(1), 69-76

Serial laboratory determinations are now routinely performed on patients admitted to intensive-care units. Adequate interpretation of such cumulative information for clinical decision-making purposes is a ... [more ▼]

Serial laboratory determinations are now routinely performed on patients admitted to intensive-care units. Adequate interpretation of such cumulative information for clinical decision-making purposes is a challenging problem. We describe a statistical method for predicting--sequentially as the data become available--the patient's outcome, death or survival. Thus, the method goes beyond previously reported techniques that base such prediction on only a single multivariate observation. The method has been applied to daily measurements of serum urea and lactate dehydrogenase, performed during one week on patients hospitalized in the coronary-care unit with acute myocardial infarction. Two baseline variables were also included in the dynamic risk index so derived: the age of the patient and the number of previous myocardial infarctions recorded on admission. We also discuss the problems of selecting the most-predictive laboratory tests and of determining for each test the amount of past data needed to achieve satisfactory prediction. We distinguish between global evaluation of the dynamic risk index obtained (in terms of specificity and sensitivity) and individual interpretation (in terms of posterior/prior probability ratio) of a given risk score for a particular patient. The approach described may contribute to more effective use of results of repeated laboratory tests on critically ill patients. [less ▲]

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See detailContinuous risk assessment using serial data in patients with myocardial infarction
Albert, Adelin ULg; Chapelle, Jean-Paul ULg; Heusghem, C. et al

Poster (1983, September)

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See detailContinuous risk assessment using serial data in patients with myocardial infarction
Albert, Adelin ULg; Chapelle, Jean-Paul ULg; Heusghem, C. et al

in European Heart Journal Supplements : Journal of the European Society of Cardiology (1983), 4(Suppl. E), 61

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See detailFirst year prognosis after myocardial infarction assassed from simple clinical findings
Smeets, J. P.; Foidart, G.; Dubois, Christophe ULg et al

Poster (1982, September)

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See detailHyperuricemia: a risk factor for acute myocardial infarction in women?
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Smeets, J. P. et al

Poster (1982, August)

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See detailSerum myoglobin determinations in the assessment of acute myocardial infarction.
Chapelle, Jean-Paul ULg; Albert, Adelin ULg; Smeets, J. P. et al

in European Heart Journal (1982), 3(2), 122-129

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