References of "Krzesinski, Jean-Marie"
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See detailÉpidémiologie de la maladie rénale chronique en République démocratique du Congo: une revue synthétique des études de Kinshasa, la capitale
Sumaili, E. K.; Krzesinski, Jean-Marie ULg; Cohen, E. P. et al

in Néphrologie & Thérapeutique (2010), 6

Chronic kidney disease (CKD) is a worldwide public health problem. Little is known about its burden in Africa. This paper reviews the knowledge of CKD in Kinshasa, summarizing four studies undertaken in ... [more ▼]

Chronic kidney disease (CKD) is a worldwide public health problem. Little is known about its burden in Africa. This paper reviews the knowledge of CKD in Kinshasa, summarizing four studies undertaken in the general population and traditional health system of Kinshasa. CKD was defined by either kidney damage (proteinuria 300 mg/day) or reduced kidney function (eGFR < 60 ml/min/1.73 m2). In the general population, the prevalence of CKD all stage is 12.4 %. Our work shows also the high prevalence of proteinuria among subjects who do not have diabetes or hypertension, the lack of early detection and management of CKD risk factors in the traditional health care system leading to late referral or premature deaths, and the limits of renal replacement treatment. CKD affects young people in the DRC, in contrast to the United States, where CKD is more prevalent in older people. Major determinants of CKD in our studies were hypertension, diabetes, overweight, age, lower socioeconomic status, and Human immunodeficiency virus (HIV) infection. Glomerular nephropathy (mainly focal segmental glomerulosclerosis) remains the leading cause of end stage renal disease. An annual screening of the population for proteinuria and CKD risk factors is feasible and will, it is hoped, provide the basis for building a nationwide prevention strategy. [less ▲]

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See detailEstimation of the Stability of Parathyroid Hormone when Stored at -80°C for a Long Period
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Hubert, Philippe ULg et al

in Clinical Journal of the American Society of Nephrology (2009), 4(12), 1988-92

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See detailMise au point sur l'hypertension artérielle chez le sujet transplanté
Krzesinski, Jean-Marie ULg

Conference (2009, November 17)

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See detailAvancées concernant l’Aliskiren (Rasilez®), inhibiteur direct de la rénine, et l’Aliskiren-hydrochlorothiazide (Rasilez HCT ®)
Boxho, G.; Krzesinski, Jean-Marie ULg; Scheen, André ULg

in Revue Médicale de Liège (2009), 64(11), 560-565

Aliskiren (Rasilez®), a direct renin inhibitor, is currently indicated for the treatment of essential hypertension, as monotherapy or in combination, especially with hydrochlorothiazide (Rasilez HCT®). It ... [more ▼]

Aliskiren (Rasilez®), a direct renin inhibitor, is currently indicated for the treatment of essential hypertension, as monotherapy or in combination, especially with hydrochlorothiazide (Rasilez HCT®). It may also be use to obtain a more complete blockade of the renin-angiotensin-aldosterone system (RAAS) when it is associated with an angiotensin converting enzyme inhibitor (ACEI) (or an AT1 angiotensin receptor antagonist) (ARA). There is some room for agents that may be more efficacious in reducing the progression of diabetic nephropathy than ACEI or ARA. In this context, the dual blockade of RAAS most probably offers a better efficacy than the simple blockade, but also exposes to a higher risk. Should ongoing trials confirm the preliminary favourable results, aliskiren might reach a forefront position among the armamentarium now available to optimize the RAAS blockade. The present article will summarize advances concerning the biochemical effects of the specific mode of action of aliskiren, especially the potential interferences related to increased renin/pro-renin levels, as well as results of recent clinical trials, not only in hypertension, but also in the fields of diabetes, renal insufficiency and cardiology. The objectives and design of the landmark study ALTITUDE will also be briefly presented. [less ▲]

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See detailPulse pressure and pulse wave velocity as markers of arterial stiffness in patients with type 1 diabetes
Philips, Jean-Christophe ULg; Xhignesse, Patricia ULg; Marchand, Monique ULg et al

Conference (2009, October 19)

Type 1 diabetes was associated with an increase in both PP and PWV as compared to a nondiabetic population. In the diabetic population, a close correlation between the two indirect markers of arterial ... [more ▼]

Type 1 diabetes was associated with an increase in both PP and PWV as compared to a nondiabetic population. In the diabetic population, a close correlation between the two indirect markers of arterial stiffness was found and also between each of them and age (or diabetes duration), but not in controls. These observations support the concept of an earier arterial stiffness in type 1 diabetes with rather poor glycemic control. [less ▲]

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See detailPrevalence of Chronic Kidney Disease in an Elderly Population: Impact of the Choice of the Equation Used for Estimating GFR
Mariat, Christophe; Cavalier, Etienne ULg; Maillard, Nicolas et al

Poster (2009, October)

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See detailL'insuffisance rénale
Krzesinski, Jean-Marie ULg

Conference given outside the academic context (2009)

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See detailL'insuffisance rénale
Krzesinski, Jean-Marie ULg

Conference given outside the academic context (2009)

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See detailHypertension, prévention, traitements et conséquences
Krzesinski, Jean-Marie ULg

Conference (2009, September 22)

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See detailPulse pressure and ambulatory arterial stiffness index (AASI) in patients wit type 1 diabetes
Philips, Jean-Christophe ULg; Marchand, Monique ULg; Saint-Remy, Annie ULg et al

Conference (2009, September 19)

Results of PP and AASI measurements performed during a 24H AMBP recording and a 3 min posture test are not superimposable, but gave complementary information, in a population with type 1 diabetes mellitus ... [more ▼]

Results of PP and AASI measurements performed during a 24H AMBP recording and a 3 min posture test are not superimposable, but gave complementary information, in a population with type 1 diabetes mellitus. Our proof-of-concept study does not support the use of AASI as a cardiovascular risk marker when calculated during a short posture test. [less ▲]

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See detailBP reduction, organ protection and CV risk : what's new?
Krzesinski, Jean-Marie ULg

in Journal de Cardiologie [= JDC] = Tijdschrift voor Cardiologie [= TVC] (2009), 21(5), 257-262

Résumé et commentaires à propos d’un symposium satellite organisé lors du 19 ème congrès de l’European Society of Hypertension tenu à Milan en juin 2009. L’HTA est un facteur majeur de risque ... [more ▼]

Résumé et commentaires à propos d’un symposium satellite organisé lors du 19 ème congrès de l’European Society of Hypertension tenu à Milan en juin 2009. L’HTA est un facteur majeur de risque cardiovasculaire. Sa détection doit être validée. Une fois définie, il faut évaluer le risque cardiovasculaire de l’hypertendu. Le contrôle de l’hypertension artérielle mérite une meilleure attention et plus d’initiatives de la part du médecin. Le traitement passe par une approche multifactorielle où les règles hygiénodiététiques sont capitales. Si nécessaire, il faut ajouter des médicaments en choisissant ceux qui sont efficaces et bien tolérés pour un traitement au long cours. Les associations ‘bloqueurs du système rénine-angiotensine et antagoniste calcique’ constituent une nouvelle approche efficace et métaboliquement plus favorable que celles où les diurétiques sont associés à ces bloqueurs de l’axe rénineangiotensine. L’association énalapril – lercanidipine offre des perspectives fort intéressantes notamment dans le haut risque cardiovasculaire pour une efficacité et une adhérence au traitement excellentes. [less ▲]

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See detailSevikar° ou Forzaten° : combinaison fixe olmésartan médoxomil-amlodipine bésylate dans le traitement de l'hypertension artérielle
Krzesinski, Jean-Marie ULg; Scheen, André ULg

in Revue Médicale de Liège (2009), 64(9), 468-473

The interest for powerful and better tolerated antihypertensive combinations is searched in the field of hypertension, because of a too large number of people still not well controlled. The recent ... [more ▼]

The interest for powerful and better tolerated antihypertensive combinations is searched in the field of hypertension, because of a too large number of people still not well controlled. The recent association between an angiotensin receptor blocker, olmesartan, and a long-acting dihydropyridine, amlodipine, reinforces our therapeutic possibilities. The synergistic effect of the two molecules potentiate the antihypertensive activity, which allows improving the quality and the rapidity of the blood pressure control. Furthermore, the fixed combination should improve patient’s compliance. The contra-indications still remain those of the sartan family. The most frequent side-effect of amlodipine monotherapy, oedema, occurs in a much lower proportion with the addition of olmesartan. [less ▲]

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See detailHypertension chez la femme: trois situations particulières
Krzesinski, Jean-Marie ULg

Article for general public (2009)

Dans cette interview du Pr Jean-Marie Krzesinski (Service de Néphrologie, CHU du Sart Tilman, ULg, Liège), seront successivement abordés les problèmes d'hypertension artérielle survenant dans le cadre d ... [more ▼]

Dans cette interview du Pr Jean-Marie Krzesinski (Service de Néphrologie, CHU du Sart Tilman, ULg, Liège), seront successivement abordés les problèmes d'hypertension artérielle survenant dans le cadre d'une contraception orale, de la grossesse ou de la ménopause. Les troubles hypertensifs survenant en cours de grossesse demandent une réeelle surveillance; si l'HTA essentielle bien contrôlée est une affection bénigne, l'apparition d'une pré-éclampsie, constatée chez 5 à 20% des femmes enceintes hypertendues, met en jeu le pronostic maternel et foetal. C'est une urgence. Lors de la ménopause, l'erreur la plus fréquente est de négliger l'accélération du risque cardiovasculaire qui affecte les femmes qui ont perdu leur protection oestrogénique. Leur prise en charge doit être aussi appliquée que chez les hommes d'âge correspondant. [less ▲]

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