References of "Kolh, Philippe"
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See detail'JBR' has been a long-term supporter of both the ESVS and the EJVES.
Naylor, A. R.; Kolh, Philippe ULg

in European Journal of Vascular and Endovascular Surgery (2013), 46(5), 505

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See detailGuideline for the surgical treatment of atrial fibrillation.
Dunning, Joel; Nagendran, Myura; Alfieri, Ottavio R. et al

in European Journal of Cardio - Thoracic Surgery (2013), 44(5), 777-91

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and its prevalence is approximately 1-2% of the general population, but higher with increasing age and in patients with concomitant ... [more ▼]

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and its prevalence is approximately 1-2% of the general population, but higher with increasing age and in patients with concomitant heart disease. The Cox-maze III procedure was a groundbreaking development and remains the surgical intervention with the highest cure rate, but due to its technical difficulty alternative techniques have been developed to create the lesions sets. The field is fast moving and there are now multiple energy sources, multiple potential lesion sets and even multiple guidelines addressing the issues surrounding the surgical treatment of AF both for patients undergoing this concomitantly with other cardiac surgical procedures and also as stand-alone procedures either via sternotomy or via videothoracoscopic techniques. The aim of this document is to bring together all major guidelines in this area into one resource for clinicians interested in surgery for AF. Where we felt that guidance was lacking, we also reviewed the evidence and provided summaries in those areas. We conclude that AF surgery is an effective intervention for patients with all types of AF undergoing concomitant cardiac surgery to reduce the incidence of AF, as demonstrated in multiple randomized studies. There is some evidence that this translates into reduced stroke risk, reduced heart failure risk and longer survival. In addition, symptomatic patients with AF may be considered for surgery after failed catheter intervention or even as an alternative to catheter intervention where either catheter ablation is contraindicated or by patient choice. [less ▲]

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See detail2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology.
Montalescot, Gilles; Sechtem, Udo; Achenbach, Stephan et al

in European heart journal (2013), 34(38), 2949-3003

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See detailWytyczne ESC dotyczace cukrzycy, stanu przedcukrzycowego i chorob ukladu sercowo-naczyniowego opracowane we wspolpracy z EASD.
Ryden, Lars; Grant, Peter J.; Anker, Stefan D. et al

in Kardiologia polska (2013), 71 Suppl 11

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See detailBenefit of revascularization for stable ischaemic heart disease: the jury is still out.
Fassa, Amir-Ali; Wijns, William; Kolh, Philippe ULg et al

in European heart journal (2013), 34(21), 1534-8

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See detailActualizacion de las guias de la Sociedad Europea de Cardiologia (ESC) para el manejo de la fibrilacion auricular de 2010 Elaborada en colaboracion con la Asociacion Europea del Ritmo Cardiaco.
Camm, A. John; Lip, Gregory Y. H.; Caterina, Raffaele De et al

in Revista espanola de cardiologia (2013), 66(1), 541-5424

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See detailA multi-scale cardiovascular system model can account for the load-dependence of the end-systolic pressure-volume relationship.
Pironet, Antoine ULg; Desaive, Thomas ULg; Kosta, Sarah ULg et al

in BioMedical Engineering OnLine (2013), 12(1), 8

ABSTRACT: BACKGROUND: The end-systolic pressure-volume relationship is often considered as a load-independent property of the heart and, for this reason, is widely used as an index of ventricular ... [more ▼]

ABSTRACT: BACKGROUND: The end-systolic pressure-volume relationship is often considered as a load-independent property of the heart and, for this reason, is widely used as an index of ventricular contractility. However, many criticisms have been expressed against this index and the underlying time-varying elastance theory: first, it does not consider the phenomena underlying contraction and second, the end-systolic pressure volume relationship has been experimentally shown to be load-dependent. METHODS: In place of the time-varying elastance theory, a microscopic model of sarcomere contraction is used to infer the pressure generated by the contraction of the left ventricle, considered as a spherical assembling of sarcomere units. The left ventricle model is inserted into a closed-loop model of the cardiovascular system. Finally, parameters of the modified cardiovascular system model are identified to reproduce the hemodynamics of a normal dog. RESULTS: Experiments that have proven the limitations of the time-varying elastance theory are reproduced with our model: (1) preload reductions, (2) afterload increases, (3) the same experiments with increased ventricular contractility, (4) isovolumic contractions and (5) flow-clamps. All experiments simulated with the model generate different end-systolic pressure-volume relationships, showing that this relationship is actually load-dependent. Furthermore, we show that the results of our simulations are in good agreement with experiments. CONCLUSIONS: We implemented a multi-scale model of the cardiovascular system, in which ventricular contraction is described by a detailed sarcomere model. Using this model, we successfully reproduced a number of experiments that have shown the failing points of the time-varying elastance theory. In particular, the developed multi-scale model of the cardiovascular system can capture the load-dependence of the end-systolic pressure-volume relationship. [less ▲]

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See detailEnregistrement des données infirmières : exploitation des données et intégration dans le financement des soins infirmiers
THONON, Olivier ULg; LEROY, Stéphanie ULg; MACLOT, Eric ULg et al

in Actes de la 6ème conférence francophone en Gestion et Ingénierie des SystèmEs Hospitaliers - GISEH (2012, September)

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See detailStructural model of the mitral valve included in a cardiovascular closed loop model. Static and dynamic validation
Paeme, Sabine ULg; Pironet, Antoine ULg; Chase, J. Geoffrey et al

in proceedings of 8th IFAC Symposium on Biological and Medical Systems, Budapest 29-31 août 2012 (2012, August 31)

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See detailAnimal Models of Mitral Regurgitation Induced by Mitral Valve Chordae Tendineae Rupture.
Leroux, Aurélia ULg; Moonen, Marie ULg; Pierard, Luc ULg et al

in Journal of Heart Valve Disease (The) (2012), 21

Background – Mitral regurgitation (MR) is a common valvular disease throughout the world. Various diagnostic techniques have been developed to assess the causes and severity of MR, and the therapeutic ... [more ▼]

Background – Mitral regurgitation (MR) is a common valvular disease throughout the world. Various diagnostic techniques have been developed to assess the causes and severity of MR, and the therapeutic approaches to this disease have been widely documented. However, treatments for chronic MR remain controversial, and various animal models of chronic MR (including chordae tendineae rupture, rapid pacing and ischemia) have been developed to study the pathophysiology and therapeutic approaches to this disease. The objective of this paper is to review the animal MR models that have been developed using a mitral valve chordae tendineae rupture technique. Animal models – Dogs and sheep have been the animals most commonly used in MR models induced by mitral valve chordae tendineae rupture, mainly due to considerations of cardiac size. Chordae tendineae cutting is performed using closed or open chest techniques. In the closed chest model, long flexible grasping forceps are positioned percutaneously in order to tear the mitral valve chordae. In the open chest model, cardiopulmonary bypass is performed and either selected chordae are cut under direct visualization, or a non specified number of chordae are cut using a metal device inserted through the left ventricular apex. Whatever the model used, MR has been found to become chronic 3 to 6 months after the induction of MR by chordae rupture. The reported mortality and complication rates of these models are high. Conclusion – In the long term, experimental evolution of chronic MR is similar to the evolution occurring naturally in patients suffering from chronic MR. These models could thus be useful in understanding the disease better and in testing new therapeutic modalities. This review summarizes the physiological effects of each of these techniques and compares the advantages and disadvantages of each procedure. [less ▲]

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See detailGuidelines on the management of valvular heart disease (version 2012).
Vahanian, Alec; Alfieri, Ottavio; Andreotti, Felicita et al

in European Heart Journal (2012), 33(19), 2451-96

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See detailThird universal definition of myocardial infarction.
Thygesen, Kristian; Alpert, Joseph S.; Jaffe, Allan S. et al

in European Heart Journal (2012), 33(20), 2551-67

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See detail2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation--developed with the special contribution of the European Heart Rhythm Association.
Camm, A. John; Lip, Gregory Y. H.; De Caterina, Raffaele et al

in Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology (2012), 14(10), 1385-413

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See detailThird universal definition of myocardial infarction.
Thygesen, Kristian; Alpert, Joseph S.; Jaffe, Allan S. et al

in Circulation (2012), 126(16), 2020-35

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