References of "Kolh, Philippe"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailAnalysis of Aortic Energetics from Pulse Wave Examination in a Porcine Study of Septic Shock
Revie, JA; Stevenson, D; Chase, JG et al

in Prceedings of BMS 2012 (2012)

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailEssential messages from the ESC/EACTS guidelines on myocardial revascularization.
Kolh, Philippe ULg; Wijns, William

in European Journal of Cardio - Thoracic Surgery (2012), 41(5), 983-5

Detailed reference viewed: 13 (2 ULg)
Full Text
Peer Reviewed
See detailInvited commentary.
Kolh, Philippe ULg

in Annals of Thoracic Surgery (2012), 93(2), 522

Detailed reference viewed: 9 (3 ULg)
Full Text
Peer Reviewed
See detailEACTS guidelines for the use of patient safety checklists.
Clark, SC; Dunning, J; Alfieri, OR et al

in European Journal of Cardio - Thoracic Surgery (2012), 41(5), 993-1004

The Safety Checklist concept has been an integral part of many industries that face high-complexity tasks for many decades and in industries such as aviation and engineering checklists have evolved from ... [more ▼]

The Safety Checklist concept has been an integral part of many industries that face high-complexity tasks for many decades and in industries such as aviation and engineering checklists have evolved from their very inception. Investigations of the causes of surgical deaths around the world have repeatedly pointed to medical errors that could be prevented as an important cause of death and disability. As a result, the World Health Organisation developed and evaluated a three-stage surgical checklist in 2007 demonstrating that complications were significantly reduced, including surgical infection rates and even mortality. Together with the results from other large cohort studies into the utility of the surgical checklist, many countries have fully implemented the use of surgical checklists into routine practice. A key factor in the successful implementation of a surgical checklist is engagement of the staff implementing the checklist. In surgical specialties such as our own it was quickly seen that there were many important omissions in the generic checklist that did not cover issues particular to our specialty, and thus the European Association for Cardio-Thoracic Surgery embarked on a process to create a version of the checklist that might be more appropriate and specific to cardiothoracic surgery, including checks on preparations for excessive bleeding, perfusion arrangements and ICU preparations, for example. The guideline presented here summarizes the evidence for the surgical checklist and also goes through in detail the changes recommended for our specialty. [less ▲]

Detailed reference viewed: 11 (3 ULg)
Full Text
Peer Reviewed
See detailAcute coronary syndromes: considerations for improved acceptance and implementation of management guidelines.
Van de Werf, Frans; Ardissino, Diego; Bueno, Hector et al

in Expert Review of Cardiovascular Therapy (2012), 10(4), 489-503

The management of acute coronary syndrome in Europe is covered by various European Society of Cardiology guidelines, which although valuable, are complex and may not always provide clear guidance in ... [more ▼]

The management of acute coronary syndrome in Europe is covered by various European Society of Cardiology guidelines, which although valuable, are complex and may not always provide clear guidance in everyday clinical practice. Consequently, implementation of the guideline recommendations is frequently suboptimal. To complicate matters further, a wealth of new data from large trials examining novel anti-thrombotic agents will become or are already available, necessitating guideline updates. This article summarizes the gaps between current guideline-recommended treatment of acute coronary syndrome and daily practice as dictated by the evidence base, including recent trials. Reasons for the suboptimal implementation of the current European Society of Cardiology guidelines and possible solutions to making these more practice oriented are presented. [less ▲]

Detailed reference viewed: 9 (3 ULg)
Full Text
Peer Reviewed
See detailStructural model of the mitral valve included in a cardiovascular closed loop model
Paeme, Sabine ULg; Moorhead, Kate; Chase, J. Geoffrey et al

Poster (2011, December)

A minimal cardiovascular system (CVS) model including mitral valve dynamics has been previously validated in silico. However parameters of this model are difficult to link with structural and anatomical ... [more ▼]

A minimal cardiovascular system (CVS) model including mitral valve dynamics has been previously validated in silico. However parameters of this model are difficult to link with structural and anatomical components of the valve. This research describes the integration of a structural model of the mitral valve in an existing closed-loop cardiovascular system (CVS) model [less ▲]

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailMathematical multi-scale model of the cardiovascular system including mitral valve dynamics. Application to ischemic mitral insufficiency
Paeme, Sabine ULg; Moorhead, Katherine; Chase, J. Geoffrey et al

in BioMedical Engineering OnLine (2011), 10(1), 86

Valve dysfunction is a common cardiovascular pathology. Despite significant clinical research, there is little formal study of how valve dysfunction affects overall circulatory dynamics. Validated models ... [more ▼]

Valve dysfunction is a common cardiovascular pathology. Despite significant clinical research, there is little formal study of how valve dysfunction affects overall circulatory dynamics. Validated models would offer the ability to better understand these dynamics and thus optimize diagnosis, as well as surgical and other interventions. A cardiovascular and circulatory system (CVS) model has already been validated in silico, and in several animal model studies. It accounts for valve dynamics using Heaviside functions to simulate a physiologically accurate “open on pressure, close on flow” law. However, it does not consider real-time valve opening dynamics and therefore does not fully capture valve dysfunction, particularly where the dysfunction involves partial closure. This research describes an updated version of this previous closed-loop CVS model that includes the progressive opening of the mitral valve, and is defined over the full cardiac cycle. Simulations of the cardiovascular system with healthy mitral valve are performed, and, the global hemodynamic behaviour is studied compared with previously validated results. The error between resulting pressure-volume (PV) loops of already validated CVS model and the new CVS model that includes the progressive opening of the mitral valve is assessed and remains within typical measurement error and variability. Simulations of ischemic mitral insufficiency are also performed. Pressure-Volume loops, transmitral flow evolution and mitral valve aperture area evolution follow reported measurements in shape, amplitude and trends. The resulting cardiovascular system model including mitral valve dynamics provides a foundation for clinical validation and the study of valvular dysfunction in vivo. The overall models and results could readily be generalised to other cardiac valves. [less ▲]

Detailed reference viewed: 65 (28 ULg)
Full Text
Peer Reviewed
See detailMinimal cardiovascular system model including a physiological description of progressive mitral valve orifice dynamics for studying valve dysfunction
Paeme, Sabine ULg; Moorhead, Katerine; Chase, J. Geoffrey et al

in XXIIIrd congress of the International Society of Biomechanics, July 3-7, 2011 (2011, July)

This research presents a new closed-loop cardiovascular system model including a description of the progressive opening and closing dynamic of the mitral valve. Furthermore, this model includes a ... [more ▼]

This research presents a new closed-loop cardiovascular system model including a description of the progressive opening and closing dynamic of the mitral valve. Furthermore, this model includes a mathematical description of the left atrium. This new CVS model enables the study of valve dysfunction in the appropriate clinical context of the overall cardiac and circulatory hemodynamics. [less ▲]

Detailed reference viewed: 65 (9 ULg)
Full Text
Peer Reviewed
See detailPatient out-of-pocket contributions related to hip fracture hospital costs in Belgium
Hiligsmann, Mickaël ULg; Gathon, Henry-Jean ULg; Bruyère, Olivier ULg et al

in Osteoporosis International (2011, March), 22(Suppl.1), 333

Detailed reference viewed: 45 (23 ULg)
Full Text
Peer Reviewed
See detailPulmonary embolism diagnostics from the driver function
Stevenson, DJ; Revie; Chase, JG et al

in Critical Care (2011), 15 (Suppl 1)

Detailed reference viewed: 12 (1 ULg)
Full Text
Peer Reviewed
See detailModel-based cardiovascular monitoring of acute pulmonary embolism in porcine trials
Revie, JA; Stevenson, DJ; Chase, JG et al

in Critical Care (2011), 15 (Suppl 1)

Detailed reference viewed: 17 (0 ULg)
Full Text
Peer Reviewed
See detailModel-based cardiovascular monitoring of large pore hemofiltration during endotoxic shock in pigs
Revie, JA; Stevenson, DJ; Chase, JG et al

in Critical Care (2011), 15 (Suppl 1)

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC).
Regitz-Zagrosek, Vera; Blomstrom Lundqvist, Carina; Borghi, Claudio et al

in European Heart Journal (2011), 32(24), 3147-97

Detailed reference viewed: 36 (2 ULg)
Full Text
Peer Reviewed
See detailAssessing the causes inducing lengthening of hospital stays by means of the Appropriateness Evaluation Protocol.
Fontaine, Pierre ULg; Jacques, Jessica ULg; Gillain, Daniel ULg et al

in Health Policy (2011)

OBJECTIVES: The objective is to evaluate the use of the Appropriateness Evaluation Protocol (AEP) as a screening tool for determining the causes of the non-justified days to help hospitals to decrease the ... [more ▼]

OBJECTIVES: The objective is to evaluate the use of the Appropriateness Evaluation Protocol (AEP) as a screening tool for determining the causes of the non-justified days to help hospitals to decrease the length of stay while preserving the quality of care. METHODS: Three successive cross-sectional surveys were conducted from 2003 till 2005, in 23 Belgian hospitals. During this period, 10921 days were audited by means of the AEP. This study is focused on adult acute non-intensive care units. The appropriateness of each day of the sample was assessed, and for those considered as inappropriate, the reasons explaining the prolongation of the stay were investigated. RESULTS: The proportion of inappropriate days was 24.61%. There is a high variability across specialties and hospitals. Regarding inappropriate days, the analysis of causes of prolongation, globally, by bed index or by hospital, indicated clearly internal and external factors that lengthen stays. The most frequent reasons are waits for an examination (22%) and the lack of extra-hospital structures (31%). CONCLUSIONS: The use of AEP as a tool of internal audit to measure the proportion of non-justified days and their causes turns out to be possible and the obtained results has provided some accurate and useful information for the participating, and allowed them to take concrete decisions which lead to shrinking of the length of hospital stay. [less ▲]

Detailed reference viewed: 39 (13 ULg)
Full Text
Peer Reviewed
See detailPatient specific identification of the cardiac driver function in a cardiovascular system model.
Hann, C. E.; Revie, J.; Stevenson, D. et al

in Computer Methods & Programs in Biomedicine (2011)

The cardiac muscle activation or driver function, is a major determinant of cardiovascular dynamics, and is often approximated by the ratio of the left ventricle pressure to the left ventricle volume. In ... [more ▼]

The cardiac muscle activation or driver function, is a major determinant of cardiovascular dynamics, and is often approximated by the ratio of the left ventricle pressure to the left ventricle volume. In an intensive care unit, the left ventricle pressure is usually never measured, and the left ventricle volume is only measured occasionally by echocardiography, so is not available real-time. This paper develops a method for identifying the driver function based on correlates with geometrical features in the aortic pressure waveform. The method is included in an overall cardiovascular modelling approach, and is clinically validated on a porcine model of pulmonary embolism. For validation a comparison is done between the optimized parameters for a baseline model, which uses the direct measurements of the left ventricle pressure and volume, and the optimized parameters from the approximated driver function. The parameters do not significantly change between the two approaches thus showing that the patient specific approach to identifying the driver function is valid, and has potential clinically. [less ▲]

Detailed reference viewed: 12 (2 ULg)
Full Text
Peer Reviewed
See detailPorcine trial validation of model-based cardiovascular monitoring of acute pulmonary embolism
Revie, JA; Stevenson, DJ; Shaw, GM et al

in Proceedings of ANZICS 2011 (2011)

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailProcessing aortic and pulmonary artery waveforms to derive the ventricle time-varying elastance
Stevenson, D; Chase, JG; Hann, CE et al

in Proceedings of the 18th IFAC World Congress, 2011 (2011)

Detailed reference viewed: 10 (0 ULg)