References of "Kirschvink, N."
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See detailClinical and functional responses to inhaled salmeterol in experimentally asthmatic cats with allergen-induced bronchospasm
Bernaerts, Frederique ULg; Leemans, Jérôme ULg; Kirschvink, N. et al

in Proceedings : 18th Congress European College of Veterinary Internal Medicine – companion animals (2008)

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See detailBarometric whole-body plethysmographic measurements in dogs suffering from brachycephalic airway obstruction syndrome.
Bernaerts, Frederique ULg; Talavera, J.; Leemans, J. et al

in Veterinary Journal (2008)

The clinical features of brachycephalic airway obstructive disease in 11 brachycephalic dogs are described in this study. The respiratory strategy was assessed before (n = 11) and after (n = 6) surgery ... [more ▼]

The clinical features of brachycephalic airway obstructive disease in 11 brachycephalic dogs are described in this study. The respiratory strategy was assessed before (n = 11) and after (n = 6) surgery using barometric whole-body plethysmography (BWBP), with the relationship between BWBP variables and the severity of the clinical signs assessed by the use of a respiratory score based on clinical, radiographic and endoscopic findings. Partial collapse of the left main bronchus was a common finding not previously described as part of the brachycephalic airway obstructive disease syndrome. Epiglottic cysts, laryngeal granulomas and nasopharyngeal turbinates in English Bulldogs were other previously unreported findings. No significant correlation between the respiratory score and any of the BWBP variables was detected. Compared to healthy dogs, brachycephalic dogs had a significantly lower Te/Ti ratio (expiratory time over inspiratory time), peak inspiratory flow (PIF) per kg bodyweight (BW), significantly higher peak expiratory flow (PEF) per kg BW, PEF/PIF, and enhanced pause. These variations are compatible with upper airway obstructions primarily in the extrathoracic airways. Following surgery, a significant decrease in PEF/PIF was detected. The study showed that BWBP could be used to characterise the respiratory strategy in brachycephalic dogs before and after surgery. [less ▲]

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See detailPregnancy-associated glycoprotein secretion in North Moroccan goats
Chentouf, M.; El Amiri, B.; Sulon, Joseph ULg et al

in Reproduction in Domestic Animals (2008), 43(6), 696-700

The plasma profile of pregnancy-associated glycoprotein (PAG) and its relationship with fetal number were studied in 14 North Moroccan goats using a semi-heterologous radioimmunoassay (RIA). Peripheral ... [more ▼]

The plasma profile of pregnancy-associated glycoprotein (PAG) and its relationship with fetal number were studied in 14 North Moroccan goats using a semi-heterologous radioimmunoassay (RIA). Peripheral blood was collected every day during the first month of pregnancy, afterward the blood samples were collected trice a week. The PAG were first detected at day 20 of pregnancy, their levels increase to week 8 of gestation then decrease slightly until parturition. Statistical differences between goats carrying one or two foetuses are observed from week 5 of pregnancy until parturition. Factorial Discriminant Analysis provides mathematical models for the discrimination between the litter size using the PAG level and the week of pregnancy. Using only one blood sample per week, high sensitivity, specificity and overall accuracy (74%, 88% and 81%) were obtained using these models. It is concluded that the PAG RIA is an effective tool for early diagnosis of pregnancy and for discrimination between the litter sizes in North Moroccan goats. [less ▲]

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See detailEffect of fish oil supplementation in a model of a feline asthma
Kirschvink, N.; Leemans, Jérôme ULg; Delvaux, F. et al

in Acta Physiologica (2008), 192(662 Suppl), 10

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See detailLe stress oxydant est modifié en fonction du statut clinique chez les trotteurs à l’entraînement
Van Erck, Emmanuelle; Lekeux, Pierre ULg; Kirschvink, N.

in 36èmes Journées AVEF (2008)

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See detailClinical and functional responses to inhaled albuterol, ipratropium bromide and combination of both in ascaris suum-sensitized cats with allergen-induced bronchospasm
Leemans, Jérôme ULg; Kirschvink, N.; Cambier, Carole ULg et al

in Proceedings: 26th Annual Symposium of the Veterinary and Comparative Respiratory Society (2008)

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See detailOral and inhaled corticosteroïds decreased eosinophilic airway inflammation and bronchial reactivity in ascaris suum-sensitized and challenged cats
Leemans, Jérôme ULg; Kirschvink, N.; Cambier, Carole ULg et al

in Proceedings: 26th Annual Symposium of the Veterinary and Comparative Respiratory Society (2008)

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See detailClinical aspects of bluetongue in ruminants
Guyot, Hugues ULg; Mauroy, Axel ULg; Kirschvink, N. et al

in Bluetongue in northern Europe (2008)

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See detailImpact de l’infection naturelle par le sérotype 8 du virus de la fièvre catarrhale ovine (BTV-8) sur la qualité de la semence des béliers
Kirschvink, N.; Raes, M.; Saegerman, Claude ULg

in Epidémiologie et Santé Animale (2008), 54

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See detailActivity of metalloproteinases mmp2 and mmp9 in matched serum and bronchoalveolar lavage fluidsamples from dogs with chronic bronchitis cvresus recurrent infectious bronchopneumonia
Bolognin, M.; Kirschvink, N.; Wiggers, L. et al

in 17th ECVIM Meeting - Budapest - Hongrie - Septembre 2007 (2007, September 13)

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See detailImpact of a natural bluetongue serotype 8 infection on semen quality of Belgian rams in 2007
Kirschvink, N.; Raes, M.; Saegerman, Claude ULg

in Veterinary Journal (2007)

In 2006, bluetongue (BT) virus serotype 8 emerged in northern Europe and numerous ruminants were affected in the following year. Infertility in males is one of the consequences of BT, although its ... [more ▼]

In 2006, bluetongue (BT) virus serotype 8 emerged in northern Europe and numerous ruminants were affected in the following year. Infertility in males is one of the consequences of BT, although its severity and duration after natural infection has not been documented. In this report, the impact of BT-8 on clinical signs and semen quality of naturally infected rams is described through a longitudinal study of two Belgian ram populations (n=12 and n=24) and a cross sectional study in a further ram population (n=43). Macroscopic semen characteristics, semen concentration, motility, percentage of living and dead spermatozoa were assessed in 167 semen samples collected on 1-6 occasions from 79 BT-8 infected rams within 5-138 days after onset of clinical disease. These were compared with healthy control animals. Significant changes in all variables were observed after natural BT-8 infection. Total recovery occurred around 85 days after clinical disease in animals undergoing a close follow-up of semen quality. Good correspondence between the results of the longitudinal and cross sectional studies suggests that semen quality of BT-8 affected rams reached normal references values 63-138 days after clinical diagnosis of BT. In addition, semen concentration seems to be a sound epidemiological indicator of ram semen quality. [less ▲]

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See detailNon-invasive assessment of airway responsiveness in healthy and allergen-sensitised cats by use of barometric whole body plethysmography
Kirschvink, N.; Leemans, Jérôme ULg; Delvaux, François et al

in Veterinary Journal (2007), 173(2), 343-352

This study aimed at determining whether airway responsiveness (AR) tests performed by use of barometric whole body plethysmography (BWBP) were repeatable in cats and to what extent AR was affected by the ... [more ▼]

This study aimed at determining whether airway responsiveness (AR) tests performed by use of barometric whole body plethysmography (BWBP) were repeatable in cats and to what extent AR was affected by the nebulization protocol used, the age of the animals, the inflammatory status of the airways and prior bronchodilator treatment. Repeatability of AR was tested on two occasions in 30 healthy cats. The concentration of carbachol inducing a 300% increase of the enhanced pause (Penh) - an estimator of airflow limitation - was calculated (C-Penh300) and did not differ significantly between the two tests (0.035 +/- 0.017% compared to 0.034 +/- 0.016%) and was significantly and positively correlated. The comparison between rapidly and slowly increasing carbachol concentrations was performed in ten healthy cats and showed a significantly lower C-Penh300 (%) when slowly increasing concentrations were used (0.037 +/- 0.013% compared to 0.039 +/- 10.015%, P < 0.05). A significant age-related increase of C-Penh300 was evidenced by performing AR tests in 15 healthy cats at 12, 18, 24 and 30 months (12 months: 0.026 +/- 0.008%, 18 months: 0.031 +/- 0.009%, 24 months: 0.038 +/- 0.01%, 30 months: 0.043 +/- 0.014%, P < 0.05). C-Penh300 significantly decreased in 12 Ascaris suum-sensitised cats after allergen exposure (0.026 +/- 0.016% compared to 0.033 +/- 0.016%, P < 0.05) and was negatively correlated with the granulocyte percentage of bronchoalveolar lavage fluid (r = -0.36, P < 0.01). Compared with a placebo inhalation, pretreatment with inhaled salbutamol significantly increased C-Penh300 in four healthy cats (0.093 +/- 0.021% compared to 0.036 +/- 0.004%, P < 0.05). This study provides evidence that AR determination by use of BWBP is promising as non-invasive indicator of lower airway inflammation or for monitoring response to bronchodilator treatment. (c) 2005 Elsevier Ltd. All rights reserved. [less ▲]

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See detailFunctional, inflammatory and morphological characterisation of a cat model of allergic airway inflammation
Kirschvink, N.; Leemans, Jérôme ULg; Delvaux, François et al

in Veterinary Journal (2007), 174(3), 541-553

The aims of this study were to characterise a model of feline allergic airway inflammation and to test through a longitudinal investigation whether five repeated allergen exposures would lead to signs of ... [more ▼]

The aims of this study were to characterise a model of feline allergic airway inflammation and to test through a longitudinal investigation whether five repeated allergen exposures would lead to signs of airway remodelling that would be detectable in vivo. Eight healthy control cats and eight cats sensitised with Ascaris suum allergens were investigated. Barometric whole body plethysmography (BWBP) was used for the assessment of respiratory variables and airway responsiveness (AR). Bronchoalveolar lavage fluid (BALF) was sampled for cytology and determination of F-2-isoprostane concentration and matrix metalloproteinase type 9 (MMP-9) activity. Thoracic radiography and bronchoscopy scores were also established. Cats were investigated prior to sensitisation and after inhalation of placebo or allergen challenge 1. BWBP measurements revealed a significant increase of enhanced pause (Penh), an index of bronchoconstriction, and AR in sensitised cats in response to allergen challenge 1. A significant increase in BALF neutrophil and eosinophil %, F-2-isoprostane concentration and MMP-9 activity, and increased radiography and bronchoscopy scores were recorded. After a recovery period of 6 weeks, all variables except BALF MMP-9 returned to baseline values. Four further allergen challenges induced similar changes to those seen in challenge I and no signs of persistent changes suggestive of bronchial remodelling were detectable. The model provides an in vivo approach to functional, inflammatory and morphological changes occurring in response to single and repeated allergen exposure. [less ▲]

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See detailChange in blood antioxidant status of horses moved from a stable following diagnosis of equine motor neuron disease
Delguste, Catherine ULg; de Moffarts, B.; Kirschvink, N. et al

in Canadian Veterinary Journal = Revue Vétérinaire Canadienne (2007), 48(11), 1165-1167

The antioxidant status of 10 horses living in stable 1 where 2 cases of equine motor neuron disease had previously been diagnosed was assessed before and 9 weeks after moving to another stable. Duration ... [more ▼]

The antioxidant status of 10 horses living in stable 1 where 2 cases of equine motor neuron disease had previously been diagnosed was assessed before and 9 weeks after moving to another stable. Duration of residence in stable 1, subsequent moving, or both, significantly affected several parameters of the antioxidant status. [less ▲]

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See detailEffects of age and Ascaris suum aerosol exposure on the pro- and antigelatinolytic activity in serum and airways of cats
Leemans, Jérôme ULg; Kirschvink, N.; Billen, Frédéric et al

in Proceedings : 17th Congress of the European College of Veterinary Internal Medicine – Companion Animals, Budapest (2007)

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See detailEffect of obesity on doxapram hydrochlorid-induced effects on whole body barometric plethysmography measurements in healthy Beagle dogs
Bolognin, M.; Bernaerts, Frederique ULg; Herpigny, F. et al

in 24th Symposium of the Veterinary Comarative Respiratory Society - Jena, Allemagne 8-10 octobre 2006 (2006, October 08)

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See detailInvestigation of airway reactivity by barometric whole body plethysmography in cats with spontaneous bronchial disease
Bernaerts, Frederique ULg; Merveille, Anne-Christine ULg; Bolognin, M. et al

in 24th Symposium of the Veterinary Comarative Respiratory Society - Jena, Allemagne 8-10 octobre 2006 (2006, October)

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See detailInvestigation of the effect of salbutamol and prenisolone on lung function test in healthy dogs with experimentally induced airway inflammation
Bolognin, M.; Talavera, J.; Bernaerts, Frederique ULg et al

in 16th ECVIM Meeting - Amsterdam - Nederlands - Septembre 2006 (2006, September)

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See detailAbsence of bronchoprotective effects to a histamine challenge test of intravenous theophylline and salbutamol in healthy dogs
Talavera, J.; Bernaerts, Frederique ULg; Kirschvink, N. et al

in 16th ECVIM Meeting - Amsterdam - Nederlands - Septembre 2006 (2006, September)

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