References of "Kaux, Jean-François"
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See detailClassification Criteria for Neurogenic Claudication Caused by Lumbar Spinal Stenosis
Genevay, Stéphane; Courvoisier, Delphine; Konstantinou, Kika et al

in EuroSpine 2016 (2016, October)

BACKGROUND Classification criteria are recommended for diseases that lack highly specific biomarkers in order to improve homogeneity in clinical research. Since imaging evidence of lumbar spinal stenosis ... [more ▼]

BACKGROUND Classification criteria are recommended for diseases that lack highly specific biomarkers in order to improve homogeneity in clinical research. Since imaging evidence of lumbar spinal stenosis (LSS) or lumbar disc herniations (LDH) may not be associated with symptoms, clinical classification criteria based upon patient symptoms and physical examination findings are required. This study sought to develop a set of criteria identifying patients with neurogenic claudication (NC) caused by LSS and patient with radicular pain (RP) caused by LDH. This abstract reports the results concerning NC caused by LSS. METHODS Phase 1: Nineteen spine specialists (clinicians and researchers) from 8 countries participated in a Delphi process, using an internet program, to rank symptoms and signs which suggest LSS as the cause of NC or DH as the cause of RP. Phase 2: Nineteen different spine specialists (surgeons and non-surgeons) from 5 countries recruited patients during office visits and classify them with a high degree of confidence as having with either: 1) NC caused by LSS 2) RP caused by LDH or 3) non-specific low back pain (NSLBP) with non-specific leg pain radiation. Patients completed survey items and specialists documented examination signs. Signs and symptoms present in ≥ 10 patients were analyzed by using Generalized Estimating Equations (GEE). Patients with NC caused by LSS or NSLBP served as controls. Items with p<0.1 in univariate analysis were entered in the multivariate analysis. A score to predict NC caused by LSS was developed based on the coefficient of the GEE, and used to obtain a ROC curve and the associated area under the curve (AUC). RESULTS A list of 46 clinical signs and 28 patient-reported symptoms were selected by the group of spine specialists during the 1st phase. For the 2nd phase, 209 patients with high confidence in the diagnosis were included 63 NC caused by LSS, 89 RP caused by DH, and 57 NSLBP with non-specific leg pain radiation. Items which predicted NC with a p-value <0.1 included age >60, bilateral leg pain, leg pain relieved by sitting, leg pain decreased by leaning or flexing, positive30 seconds extension test, negative straight leg raise test. The score had an AUC of 0.91, and the cutoff to obtain a specificity of 92.1% resulted in a sensitivity of 80.0%. CONCLUSION An international collaboration of surgeon and non-surgeon spine specialists produced a set of diagnostic criteria with high specificity and sensitivity for identifying patients with NC caused by LSS. Using this set could improve the quality of basic science and clinical research in this field by improving homogeneity within groups of patients. [less ▲]

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See detailAdaptation interculturelles du questionnaire "Patient-Rated Tennis Elbow Evaluation" pour les patients francophones
Kaux, Jean-François ULiege; DELVAUX, François ULiege; SCHAUS, Jean ULiege et al

in 9ème Congrès commun SFMES - SFTS (2016, September)

Contexte: L’épicondylite latérale est une blessure commune chez les joueurs de tennis et les travailleurs physiques pour qui il existe un questionnaire en anglais qui en évalue la sévérité. Le ... [more ▼]

Contexte: L’épicondylite latérale est une blessure commune chez les joueurs de tennis et les travailleurs physiques pour qui il existe un questionnaire en anglais qui en évalue la sévérité. Le questionnaire « Patient-Rated Tennis Elbow Evaluation » (PRTEE) mesure la douleur et l’incapacité fonctionnelle du coude chez les patients souffrant d’une épicondylite latérale. Le questionnaire a déjà été traduit en suédois, en turc, en québécois, en italien, en néerlandais et en grec. Objectifs : Le but de cette étude est de traduire et de réaliser une adaptation interculturelle du questionnaire PRTEE en français et d’en évaluer sa fiabilité et sa validité. Matériel et Méthodes : Le PRTEE a été adapté interculturellement en français selon les lignes directrices internationales. Les participants (n=115) ont rempli le PRTEE-F, deux fois avec un intervalle de 30 minutes, le questionnaire Disabilities of Arm, Soulier and Hand (DASH), et le Short Form Health Survey (SF-36) pour évaluer la fiabilité et la validité du PRTEE-F. La cohérence interne (avec l’alpha de Cronbach), la fidélité test-retest (avec la corrélation intra-classe (ICC)) et la validité de construit (avec le coefficient de corrélation de Spearman). Résultats : Le PRTEE-F montre une fidélité test-retest bonne pour le score total (ICC 0,83) et pour les différents items (ICC 0,71-0,9). La traduction française possède une cohérence interne élevée (0,98). La corrélation entre le PRTEE-F et le DASH est forte pour le score total (rs=0,92, p<0.001), pour le sous-total symptomatique (rs=0,86, p<0.001) et fonctionnel (rs=0,93, p<0.001). Le PRTEE-F possède une corrélation forte avec une partie des sous-échelles convergentes du SF-36 (PF, RP et BP). Il y a une corrélation faible ou modérée avec les sous-échelles divergentes du SF-36 (REm, MH, SF et VT). Il n’y a pas d’effet plancher et plafond. Conclusion : La version française du questionnaire PRTEE a été adaptée interculturellement avec succès, et cette étude a montré que le PRTEE-F est fiable et valide pour évaluer les patients francophones souffrant d’une épicondylite latérale. [less ▲]

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See detailImpact d’une réathlétisation précoce sur les performances des sportifs opérés d’une rupture du ligament croisé antéro-externe du genou
Duval, Thomas; Kaux, Jean-François ULiege; LEHANCE, Cédric ULiege et al

in 9ème Congrès commun SFMES - SFTS (2016, September)

Introduction : La reconstruction du ligament croisé antéro-externe du genou est une chirurgie lourde qui est suivie d’une longue période de rééducation. Le retour au sport après cette opération reste ... [more ▼]

Introduction : La reconstruction du ligament croisé antéro-externe du genou est une chirurgie lourde qui est suivie d’une longue période de rééducation. Le retour au sport après cette opération reste toutefois un défi. Plus d’un tiers des athlètes est incapable de reprendre son activité au même niveau. La peur de subir un nouvel accident reste un obstacle majeur à cette reprise sportive et la persistance de déficits fonctionnels est la première cause de récidives de déchirure ligamentaire. Matériels et méthodes : Notre échantillon comprend dix sujets, cinq dans le groupe bénéficiant d’une réathlétisation précoce et cinq dans le groupe témoin. Le premier groupe réalise une séance de réathlétisation précoce hebdomadaire (à raison d’une fois par semaine et ce, durant six mois) associée à la rééducation en kinésithérapie durant une durée de six mois. Le deuxième groupe bénéficie uniquement de séances de kinésithérapie classique respectant un protocole bien défini du CHU de Liège. Nous avons choisi de réaliser, en pré-opératoire, dans les deux groupes, un test isocinétique. En post-opératoire (après six mois), les sujets des deux groupes ont réalisé dans l’ordre suivant : un test isocinétique, un questionnaire de KOOS et enfin des tests fonctionnels (Hop test). Les séances de réathlétisation et de kinésithérapie sont suivies selon un protocole spécifique respectant l’individualisation propre à chaque patient. Résultats : L’analyse des tests isocinétiques et du questionnaire de KOOS, nous a permis de constater des différences entre les deux groupes au niveau des valeurs chiffrées mais qui ne sont cependant pas significatives (P level= 0,07). Par contre, l’analyse des résultats obtenus dans les tests fonctionnels (tests de sauts en longueur évaluant la performance en distance) a montré des différences significatives (P level= 0,04 pour le single hop et le triple hop test, P level= 0,02 pour le cross over hop test) entre les deux groupes et celles-ci sont au bénéfice du groupe ayant bénéficié d’une réathlétisation précoce. Conclusion : Dans cette étude, nous constatons une amélioration globale des performances en faveur du groupe ayant bénéficié d’une réathlétisation précoce. Cependant lors de l’analyse statistique et ce surtout concernant dans le test isocinétique, peu d’éléments évoluent de manière significative voir aucun pour le questionnaire de KOOS. Le faible échantillonnage de cette étude préliminaire intervient certainement dans ce constat. [less ▲]

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See detailTraduction inter-culturelle et validation du Kujala Anterior Knee Pain Scale (AKPS) en français
Kaux, Jean-François ULiege; Bornheim, Stephen ULiege; Remy, Gaël et al

in 9ème Congrès commun SFMES - SFTS (2016, September)

Introduction : Le syndrome fémoro-patellaire est l'un des problèmes de genou les plus répandus qui se caractérise par une douleur antérieure du genou dans des activités mettant en charge l'articulation ... [more ▼]

Introduction : Le syndrome fémoro-patellaire est l'un des problèmes de genou les plus répandus qui se caractérise par une douleur antérieure du genou dans des activités mettant en charge l'articulation fémoro-patellaire. Le Kuala Anterior Knee Pain Scale (Kujala AKPS) est un questionnaire utilisé pour évaluer les symptômes subjectifs, tels que les limitations fonctionnelles et la douleur antérieure du genou. Le questionnaire a déjà été traduit et validé en portugais brésilien, en persan, en chinois, en turque, et en néerlandais. Le but de cette étude est de traduire ce questionnaire en français afin d'en évaluer sa fiabilité et sa validité. Matériel et méthode : La traduction et l’adaptation interculturelle du questionnaire a été adaptée selon les recommandations internationales qui se présentent en 6 étapes : traduction initiale, synthèse des traductions, traduction de retour vers la langue d’origine, comité d'experts, test de la version pré-finale et approbation du comité experts. Une fois la version française obtenue, les participants (n=101) ont remplis 2 fois le Kujula AKPS avec un intervalle de 7 jours, et le Short Form Health Survey (SF-36) afin d'en évaluer les propriétés psychométriques (la cohérence interne, la fidélité test-retest et la validité de construit). Résultats : Le Kujula AKPS montre une fidélité test-retest élevée pour le score total (ICC 0,97). La traduction française possède une cohérence interne élevée (0,87). Le Kujula AKPS possède une corrélation forte avec une partie des sous-échelles convergentes du SF-36 (PF, RP et BP). Il y a une corrélation faible ou modérée avec les sous-échelles divergentes du SF-36 (MH, SF et VT). Il n’y a pas d’effet plancher et plafond. Conclusion : La version française du questionnaire Kujula AKPS étant compréhensible, semble avoir une bonne adaptation interculturelle. Cette étude a démontré que le Kujula AKPS-F est fiable et valide pour les patients francophones souffrant d'un syndrome rotulien. [less ▲]

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See detailThe cardiovascular impact of intense eccentric isokinetic exercise versus aerobic treadmill running
LE GOFF, Caroline ULiege; Kaux, Jean-François ULiege; LAURENT, Terry ULiege et al

in Isokinetics & Exercise Science (2016), 24(3), 201-208

BACKGROUND: Regular physical activity is an important health factor, but intense physical stress can increase the risk of heart disease. OBJECTIVE: Our aim was to determine the potential cardiac ... [more ▼]

BACKGROUND: Regular physical activity is an important health factor, but intense physical stress can increase the risk of heart disease. OBJECTIVE: Our aim was to determine the potential cardiac repercussions of, and the oxidative stress resulting from a maximal eccentric isokinetic exercise and a 1-hour treadmill run at 75% ˙V O2 max (maximal exercise done 6 weeks before). METHODS: Twelve young sedentary healthy subjects randomly performed two tests separated by 6 weeks: 1) 3 sets of 30 maximal eccentric isokinetic contractions of the quadriceps; 2) a 1-hour running on treadmill at 75% ˙V O2 max. We drew blood samples just before each exercise (T1), and just after (T2), 3 hours after (T3), and 24 hours after (T4) the end of each exercise to measure cardiac and oxidative stress biomarkers. RESULTS: In the running group, we observed significant differences for myoglobin (T3: 145 ± 80 μg/L), creatinine kinase (T4: 593 ± 350 mg/L), oxidized glutathione (T2: 22 ± 15.6 μmol/L), and highly sensitive cardiac troponin T, (T3: 0.051 ± 0.038 ng/mL). In the isokinetic group, we observed significant differences for myoglobin (T3:1419 ± 2533 mg/L), creatine kinase (3303 ± 7159 mg/L), and oxidized glutathione (T4:24 ± 14 μmol/L). Between isokinetic exercise and running, we observed significant differences for uric acid (p < 0.05, running > eccentric), myoglobin (p < 0.05, ditto), NT-proBNP (p < 0.05, ditto), hsTnT (p < 0.01, ditto), and oxidized glutathione (p < 0.05). CONCLUSIONS: As cardiac biomarkers appear practically unmodified after the isokinetic exercise, despite the considerable oxidative stress, we suggest that the application of intense maximal eccentric isokinetic exercise, when indicated, should be safe for most patients including those whose cardiac status is unknown. On the other hand, the increase in cardiac biomarkers observed after running, could reflect leakage of these biomarkers from the cytosolic pool of cardiac cells, linked to membrane damage, rather than the result of a major injury and hence running is supposed to be a safe practice. However, since sudden death during running has been previously described, assesment of the cardiac biomarkers and a follow-up by a sport doctor is important especially if there is a cardiac family history. [less ▲]

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See detailRelation entre hygiène bucco-dentaire et tendinopathies chez les sportifs
Kipgen, Laurence; Kaux, Jean-François ULiege; Rompen, Eric ULiege et al

in Science & Sports (2016), 31(4), 227-229

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See detailRelease of cardiac biomarkers during a cycling race
LE GOFF, Caroline ULiege; Kaux, Jean-François ULiege; D'OTREPPE DE BOUVETTE, Stéphanie ULiege et al

in World Journal of Cardiovascular Diseases (2016), 6(8), 285-294

Objectives: Over the past two decades, a large interest in cardiac marker elevations has developed in endurance sports events. The intense effort is not without risk. We aim to see if the relatively ... [more ▼]

Objectives: Over the past two decades, a large interest in cardiac marker elevations has developed in endurance sports events. The intense effort is not without risk. We aim to see if the relatively cardiospecific biomarkers could show the damage on cardiac muscle cells. Methods: Fourteen cyclists were recruited for an international race (177km). We studied the release of injury related cardiac markers, risk related cardiac markers, renal function markers and blood cytology. The subjects were submitted to three blood test: one before (T0), one just after (T1) and the last one 3 hours after the race (T3). Results: Blood cytology markers, namely erythrocytes, hemoglobin, hematocrit, and average hemoglobin concentration, were found to evolve in a similar way. Renal function markers, such as creatinin, cystatin C and uric acid, showed a post effort increase that might be related to renal blood flow depletion during exercise. Cardiac and muscular markers were all increased at T1. Conclusions: Physiological stress induced by an international cycling race certainly has consequences on cardiac muscle cells. Fortunately, those blood concentration variations are more representative of a transitional state, due to an imbalance created by an intense aerobic effort maintained during several hours, rather than an irreversible injury. [less ▲]

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See detailImpact of a mountain ultra-marathon (UTMB) on cardiac biomarkers
Le Goff, Caroline ULiege; Gergelé, Laurent; Kaux, Jean-François ULiege et al

in European journal of sport sciences (2016, July)

Objectives. While moderate exercise has beneficial effects on the cardiovascular system, consequences of a supra-physiological effort are not clear yet. In particular, the physiological consequences of ... [more ▼]

Objectives. While moderate exercise has beneficial effects on the cardiovascular system, consequences of a supra-physiological effort are not clear yet. In particular, the physiological consequences of ultramarathons need to be further documented. The aim of the study was to assess the changes of various cardiac biomarkers after a mountain ultra-marathon. Material and methods. Blood and urine samples were collected on 28 runners (17 men) participating to the Ultra-Trail du Mont Blanc (105km, total positive elevation: 5600 m) at 3 different times: before the race (Pre), within 1 h after the finish (Post) and 7 days after the finish (D+7). Several biomarkers involved in heart disease (coronary syndrome, heart failure and fibrosis) and in inflammation were assayed on different analyzers such a COBAS® (for CKMB,TnThs, NT-proBNP, H-FABP and CRPs) and KRYPTOR® (for Copeptin). ST2 was measured manually with the Presage kit from CRITICAL DIAGNOSTIC®. Results. Plasma levels of cardiac markers (CKMB, TnThs, NT-proBNP, copeptin, H FABP, ST2) and inflammation (CRPs) increased significantly at Post. Means values increased from Pre to Post as follows: 2.3 to 91.9 UI/L for CKMB (p<0.0001); 7.6 to 31.7 ng/L for TnThs (p<0.0001); 41.7 to 1190.5 ng/L for NT-proBNP, 4.2 to 22.9 pmol/L for copeptin (p=0.001); 3.6 to 107.8 ng/mL for H-FABP (p<0.0001), 29.7 to 126.2 ng/mL for ST2 (p<0.0001); 0.5 to 29.1 mg/L for CRPs (p<0.0001). With the exception of a few (H-FABP, ST2, CRPs) biomarkers in some subjects, all values were back to Pre values at D+7. Discussion-conclusion. Prolonged strenuous running exercise caused an elevation in cardiac biomarkers. Elevation in CK-MB levels lacks specificity for cardiac damage as runners have increased CKMB from skeletal muscles as well. Previous studies suggested that exercise induced TnThs elevation is a benign reversible physiologic phenomenon but this parameter, as well as H-FABP, could be a sign of ischemia. Different phenomena occurred such as stretch of myocytes causing an increase in pressure or volume and neurohormonal activation which can explain the Copeptine and NT-proBNP increase, while ST2 is a biomarker of cardiac remodeling and fibrosis. CRP is an acute phase compound that tends to increase following a strenuous and prolonged bout of exercise and/or muscular injury. As the values tended to return within the normal reference range values within 7 days after the race, our study suggests that there is no permanent structural damage at the myocardium level. [less ▲]

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See detailValidity and reliability of the French translation of the Patient-Related Tennis Elbow Evaluation Questionnaire
Kaux, Jean-François ULiege; DELVAUX, François ULiege; SCHAUS, Jean ULiege et al

in Crossing borders through sport science (2016, July)

Background: The lateral elbow tendinopathy is a common injury in tennis players and physical workers. The Patient-Rated Tennis Elbow Evaluation (PRTEE) questionnaire was created to measure pain and ... [more ▼]

Background: The lateral elbow tendinopathy is a common injury in tennis players and physical workers. The Patient-Rated Tennis Elbow Evaluation (PRTEE) questionnaire was created to measure pain and functional disabilities specifically reported in patient with lateral epicondylitis (tennis elbow). Developed in English, this questionnaire has since then been translated into several languages but not in French. Objectives: The aims of the study were to translate and cross-culturally adapt the PRTEE questionnaire into French and to evaluate the reliability and validity of this new version of the questionnaire (PRTEE-F). Methods: The PRTEE was cross-culturally adapted into French according to the international guidelines. To assess the reliability and validity of the PRTEE-F, 115 participants filled in the PRTEE-F twice, and the Disabilities of Arm, Shoulder and Hand questionnaire (DASH) and the Short Form Health Survey (SF-36) once. Internal consistency (with Cronbach’s alpha), test-retest reliability (with intra-class correlation (ICC)), convergent and divergent validity (by calculating the Spearman’s correlation coefficients with the DASH and some sub scales of the SF-36, respectively) were assessed. Results: The PRTEE was translated in French without problem. PRTEE-F showed a good test-retest reliability for the overall score (ICC 0.83) and for each items (ICC 0.71-0.9) and a high internal consistency (Cronbach’s alpha = 0.98). The correlation analyses revealed high correlation coefficients between PRTEE-F and DASH (good convergent validity) and, as expected, a low or moderate correlations with the divergent subscales of the SF-36 (discriminant validity). There was no floor or ceiling effect. Conclusions: The PRTEE questionnaire was successfully cross-culturally adapted into French the PRTEE-F is reliable and valid for evaluating the French-speaking patient with lateral elbow tendinopathy. [less ▲]

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See detailUn neurinome intra-canalaire lombaire
Manto, Florence; HOUET, Elise ULiege; LACREMANS, Pierre ULiege et al

in Revue Médicale de Liège (2016), 71(6), 269-271

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See detailLes lésions musculo-squelettiques de l’adolescent sportif
Kaux, Jean-François ULiege

in 14èmes Journées de l’Enseignement Post-Universitaire de la Faculté de Médecine de Liège (2016, May 21)

Le développement des activités sportives augmente la fréquence des lésions musculo-squelettiques de l’adolescent. Ces lésions dépendent non seulement du mécanisme mais également de l’âge du sportif et de ... [more ▼]

Le développement des activités sportives augmente la fréquence des lésions musculo-squelettiques de l’adolescent. Ces lésions dépendent non seulement du mécanisme mais également de l’âge du sportif et de sa maturation osseuse, particulièrement des noyaux d’ossification. Les aphophysoses, ostéochondroses ou ostéodystrophies se manifestent par une douleur au niveau de l’insertion tendineuse sur le noyau d’ossification secondaire en croissance. Elles sont souvent provoquées par des contraintes en traction-cisaillement chez des enfants sportifs entre 3 et 16 ans. L’excès pondéral constitue également un facteur de risque. La guérison spontanée s’observe généralement après trois à 12, voire 18 mois d’évolution. La maladie de Sever est l’ostéodystophie du pied la plus fréquente ; elle touche le noyau postérieur du calcanéum, qui apparaît entre sept et dix ans et qui fusionne à la fin de la puberté (16–18 ans) et sur lequel s’insèrent le tendon d’Achille et le court fléchisseur plantaire. Les contraintes en traction et compression (réception de saut) sont importantes à ce niveau surtout chez les sportifs de sept à 15 ans pratiquant diverses impulsions (basket-ball, volley-ball, saut en longueur. . . ). La talalgie se manifeste lors de la pratique sportive. La douleur est bilatérale dans 60% des cas. Il faut rechercher des troubles de statique plantaire (pieds creux) régulièrement associés à la maladie de Sever. Le bilan radiologique reste souvent décevant et peu spécifique. Le diagnostic différentiel doit s’établir avec une tendinopathie achilléenne, une fracture du calcaneus, un kyste osseux, un ostéome ostéoïde, une ostéomyélite ou une éventuelle enthésopathie (spondylarthropathie). La base du traitement est le repos sportif en phase algique, l’usage de la cryothérapie, le port de talonnettes amortissantes ou encore la prise temporaire d’AINS (ibuprofène). Au niveau du genou, l’apophysose de croissance la plus fréquente est la maladie d’Osgood-Schlatter qui est plus fréquente chez les adolescents pratiquant des sports de sauts. Au niveau du bassin tous les noyaux d’ossifications peuvent être atteints et même être le site de fractures-avulsions lors de contractions musculaires excessives ou brutales car le cartilage de croissance présente une faiblesse locale par rapport aux structures musculo-tendineuses. L’ostéochondrite disséquante correspond à un noyau osseux séparé du corps de l’os et recouvert de cartilage normal ; localisée à la partie supéromédiale du talus ou au niveau des condyles fémoraux. Elle est souvent asymptomatique, voire entraine une discrète limitation douloureuse de la mobilisation mais entraine une douleur à la palpation locale. Elle nécessite cependant un traitement adéquat. En cas de lésion peu ou pas évolutive, une surveillance radiologique (IRM / arthroscanner) est suffisante. Chez le très jeune adolescent une immobilisation plâtrée de six semaines permettrait la fusion du noyau (au niveau du dôme talien). L’arthroscopie sera justifiée en cas de séquestre osseux afin de l’extraire, et ce, avec de bons résultats postopératoires. L’ostéosynthèse d’un noyau volumineux peut être également indiquée, les résultats restant plus aléatoires. En conclusion, la pathologie traumatique ou microtraumatique de l’adolescent sportif n’est pas rare et ne doit jamais être négligée. Toute douleur exige une exploration radiologique comparative afin de poser un diagnostic précis et d’entreprendre un traitement adéquat, le plus souvent conservateur. [less ▲]

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See detailEchographie nerveuse
Kaux, Jean-François ULiege

Conference (2016, May 03)

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See detailSelf-Medication Practice among Amateur Runners: Prevalence and Associated Factors
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; LARBUISSON, Robert ULiege et al

in Journal of Sports Science & Medicine (2016), 15(2), 387-8

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See detailCross-cultural adaptation and validation of the victorian institute of sport assessment-patella questionnaire for French-speaking patients with patellar tendinopathy
Kaux, Jean-François ULiege; Delvaux, François ULiege; Oppong-Kyei, Julian et al

in Journal of Orthopaedic & Sports Physical Therapy (2016), 46(5), 384-393

Study Design Clinical measurement study. Background The Victorian Institute of Sports Assessment–Patellar tendinopathy questionnaire (VISA-P), originally developed in English, assesses the severity of ... [more ▼]

Study Design Clinical measurement study. Background The Victorian Institute of Sports Assessment–Patellar tendinopathy questionnaire (VISA-P), originally developed in English, assesses the severity of patellar tendinopathy symptoms. No French version of the questionnaire exists. Objectives The aim of our study was to translate the VISA-P in French and verify its psychometric properties. Methods The translation and cultural adaptation were performed according to international recommendations in six steps: initial translation, translation merging, back translation to the original language, expert committee to reach a pre-final version, test of the pre-final version, and expert committee appraisal of a final version. Afterwards, the psychometric properties the final French version (VISA-PF) were assessed in 92 subjects, divided into three groups: pathological subjects (n = 28), asymptomatic subjects (n = 22) and sports-risk subjects (n = 42). Results All members of the expert committee agreed with the final version. On a scale ranging from 0 to 100 (asymptomatic subject), the average scores of the VISA-PF obtained were 53 (± 17) for the pathological group, 99 (± 2) for the healthy group and 86 (± 14) for the sports-risk group. The test-retest reliability of the VISA-PF was excellent and good internal consistency. Correlations between the VISA-PF and diverging validity of the SF-36 were low and the correlation coefficient values measured between the VISA-PF scores and converged items of the SF-36 were higher. Conclusion The VISA-PF is understandable, valid and suitable for French-speaking patients with patellar tendinopathy. [less ▲]

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See detailPlatelet Rich Plasma for Treating Chronic Tendinopathy
Kaux, Jean-François ULiege

in Aspetar Sports Medicine Journal (2016), 4(1), 118-122

Tendinopathy is a major problem in medicine and sports traumatology. It is due, inter alia, to mechanical overload. It remains a challenge for the medical world to the extent that its frequent resistance ... [more ▼]

Tendinopathy is a major problem in medicine and sports traumatology. It is due, inter alia, to mechanical overload. It remains a challenge for the medical world to the extent that its frequent resistance to conventional treatments never promises the patient a favourable response following therapeutic management. The development of platelet-rich plasma (PRP) is a new hope when therapeutic treatments such as NSAIDs, corticosteroid injections, eccentric rehabilitation, shock waves, etc. have shown their limits. Furthermore, since January 2011, it is no longer included on the list of doping substances (http://www.wada-ama.org/). Indeed, platelets contain various growth factors (PDGF, TGF-β, FGF, VEGF, HGF, IGF-1) which participate to the tendon healing process. PRP is obtained by centrifugation of autologous blood to obtain a platelet concentration greater than that of the blood, which varies according to the production method. PRP also contains a variable amount of lymphocytes and erythrocytes that can have a detrimental effect on wound healing. Currently, there is no formal consensus regarding the production method or the biological composition of PRP. Many laboratory studies (in vitro and/or on animal) emphasize the acceleration of the healing tendon process after injection of PRP, each growth factor exerting a specific action during healing. PRP would cause the proliferation, migration and differentiation of cells derived from circulation, improving the initial phase of the tendon healing. This anabolic process initiates the type I collagen synthesis. Although currently the effectiveness of PRP on tendon healing in vitro or in animals seems to be confirmed, clinical studies are currently still controversial. In addition, there is still only a limited number of randomized and controlled studies reviewing PRP for treating tendinopathy. However, it seems that PRP can be efficient to treat lateral epicondylitis, patellar tendinopathies and plantar fasciitis, even if the level of proofs remains low. Up to now there is not enough proofs concerning the use of PRP to treat rotator cuff or Achilles tendinopathies. More randomized, controlled and blinded studies remain needed. In conclusion, experimentally, PRP, through the local release of various growth factors stimulates tendon healing. This therapy could optimize the healing of pathological human tendons. PRP should be analysed to see whether it improves tendon healing in both humans and animals through other randomized controlled trials. [less ▲]

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See detailValidity of algometry and video assessment to diagnose pain in sheep with knee synovitis
Niessen, J; Nisolle, JF; Hontoir, F et al

Poster (2016, April 23)

Reasons to perform study. To assess lameness in animals, semi-objective scales are used. Video is sometimes used to enable blinding of the clinician. In addition, the assessment of pain is particularly ... [more ▼]

Reasons to perform study. To assess lameness in animals, semi-objective scales are used. Video is sometimes used to enable blinding of the clinician. In addition, the assessment of pain is particularly difficult in animals since they cannot report their feelings. The interpretation of the reactions of the animals can be different between observers. A method to quantify pain is the measure of mechanical nociceptive thresholds (MNT), a method called algometry. Since synovitis is often linked to swelling of periarticular tissues and to synovial fluid effusion, palpation of the joint is also a useful test. The objectives of the current study were to assess in sheep whether (1) video assessment of lameness is in agreement with real observation; (2) algometry of the knee is correlated with lameness evaluation; (3) algometry is correlated with identification of swelling by palpation. Material and methods. The population of sheep enrolled in a controlled trial at the Ovine Research Center of UNamur was used for the current study. Results. There was a moderate inter-rater agreement (value of kappa was 0,41) between the experimenter who evaluated the ewes on site and the one who watched the videos. No significant correlation was identified between lameness scores and algometry. A negative correlation (algometry reactive threshold is lower when palpation score is higher) was identified between palpation scores and MNT (P<0.05). Discussion. Video assessment can be used in research to assess lameness. The experience of the observer must be taken into account. Algometry is not entirely valid since an adaptation or learning process seems to develop in sheep. [less ▲]

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See detailActualités dans la prise en charge des tendinopathies
Kaux, Jean-François ULiege

Conference (2016, April 16)

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See detailNew conservative and regenerative treatments for cartilage and tendon lesions
Kaux, Jean-François ULiege

Conference (2016, April 05)

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See detailExploring the effect of a second closely-timed infiltration of platelet-rich plasma to treat proximal patellar tendinopathies
Kaux, Jean-François ULiege; CROISIER, Jean-Louis ULiege; FORTHOMME, Bénédicte ULiege et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 54(Suppl. 1 No. 2), 199

Intorduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Intorduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. Purpose: The aim of this study was to evaluate whether 2 infiltrations of PRP proves more effective than a single treatment. Methods: Twenty patients suffering from chronic jumper’s knee were enrolled into the study and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. Discussion and Conclusion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups at short to mid term. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. A second infiltration should perhaps be envisaged later, but this remains to be demonstrated. [less ▲]

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See detailGood prognosis factors after a platelet rich plasma (PRP) injection for tendinopathies ?
Kaux, Jean-François ULiege; Sancerne, Audrey; Libertiaux, Vincent ULiege

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 251

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors ... [more ▼]

Introduction : Platelet-rich plasma injections are a recent treatment for chronic tendinopathies. However, this theraeutic remains controversed in litterature. Up to now, there is no prognosis factors identified to predict a good evolution after injection of PRP. Purpose: The aims of this study were to evaluate the effect of PRP injection followed by a standardized reeducation protocol among patients suffering from different tendinopathies and to determine the good prognosis factors, if any. Methods : 51 patients suffering from different tendinopathies and refractory to conventional physiotherapy were treated with a PRP injection. Prior to the injection, a blood sample was drawn and some biological parameters (glycemia, cholesterol level, …). A pain assessment was then made using a visual analog scale (VAS) and a pressure algometer. The same assessment was carried out after 6 weeks and 12 weeks when possible. Results : There is an overall significant improvement VAS score at the end of the 12 weeks follow- up. However, no correlation was found between the evolution of the clinical scores and the biological parameters measured. Discussion and Conclusions : A PRP injection followed by a program of eccentric rehabilitation positively affects the algo-functional scores of patients with tendinopathie who were refractory to conventional physiotherapy, whatever their initial biological parameters. [less ▲]

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