References of "Kaux, Jean-François"
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See detailEccentric training for tendon healing after lesion: a rat model
Kaux, Jean-François ULg; Libertiaux, Vincent ULg; Leprince, Pierre ULg et al

in American Journal of Sports Medicine (2017), 45(6), 1440-1446

BACKGROUND:The tendon is a dynamic entity that remodels permanently. Platelet-rich plasma (PRP) injection has been shown to have a beneficial effect on tendon healing after lesion in rats. Furthermore ... [more ▼]

BACKGROUND:The tendon is a dynamic entity that remodels permanently. Platelet-rich plasma (PRP) injection has been shown to have a beneficial effect on tendon healing after lesion in rats. Furthermore, eccentric exercise seems to improve the mechanical quality of the tendon. HYPOTHESIS:A combination of PRP injection and eccentric training might be more effective than either treatment alone. STUDY DESIGN:Controlled laboratory study. METHODS:Adult male rats were anesthetized, an incision was performed in the middle of their left patellar tendon and an injection of physiological fluid (PF) or homologous PRP was randomly made at the lesion level. The rats were then divided into 2 groups: the eccentric group, undergoing eccentric training 3 times a week, and the untrained group, without any training. Thus, 4 groups were compared. After 5 weeks, the tendons were removed and their ultimate tensile strength and energy were measured. Tendons were frozen for proteomic analyses when all biomechanical tests were completed. Statistical analysis was performed with linear mixed effect models. RESULTS:No significant difference was found between the treatments using PF injection or PRP injection alone. However, the value of the ultimate tensile force at rupture was increased by 4.5 N (108% of control, P = .006) when eccentric training was performed. An intragroup analysis revealed that eccentric training significantly improved the ultimate force values for the PRP group. Proteomic analysis revealed that eccentric training led to an increase in abundance of several cytoskeletal proteins in the PF group, while a decrease in abundance of enzymes of the glycolytic pathway occurred in the PRP treated groups, indicating that this treatment might redirect the exercise-driven metabolic plasticity of the tendon. CONCLUSION: Eccentric training altered the metabolic plasticity of tendon and led to an improvement of injured tendon resistance regardless of the treatment injected (PF or PRP). CLINICAL RELEVANCE:This study demonstrates the necessity of eccentric rehabilitation and training in cases of tendon lesion regardless of the treatment carried out. [less ▲]

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See detailPlatelet-rich plasma versus hyaluronic acid to treat patellar tendinopathies
Kaux, Jean-François ULg; Roberjot, Mathieu; SAMSON, Antoine ULg

in The Future of Football Medicine (2017, May)

Introduction: The treatment of patellar tendinopathies could be difficult. This is the reason why new treatments have been developed, among which platelet rich plasma (PRP) injections. Some clinical ... [more ▼]

Introduction: The treatment of patellar tendinopathies could be difficult. This is the reason why new treatments have been developed, among which platelet rich plasma (PRP) injections. Some clinical series have previously evaluated the effect of PRP in the treatment of proximal patellar tendinopathies. Recent systematic review concluded that PRP could be recommend as a treatment in such indication (1). Recently, the viscoelastic properties of hyaluronic acid (HA) on liquid connective tissue have been proposed for the treatment of tendinopathies (2). Some fundamental studies show encouraging results on HA’s ability to promote tendon gliding and reduce adhesion as well as to improve tendon architectural organisation. Some observations also support its use in a clinical setting to improve pain and function. Purpose: We aimed to compare the effect of PRP injection versus two injections of HA after three months on patients who have a proximal patellar tendinopathy. Methods: Eleven leisure football players with proximal patellar tendinopathies being not relieved after minimum three months of physiotherapy treatments where included. Six of them (group 1: 29.5±9.9 y.o.; 78.9±12.8kg; 177.4±6;9cm) have received a leukocyte poor PRP injection (obtained using an aphaeresis machine) under US guidance. This technique of PRP collection enable to obtain reproducible pure PRP with the same chosen concentration of 850 000 platelets/microliter. The other five subjects (group 2: 29.3±8.1 y.o.; 77.1±10.6kg; 178.1±5.8cm) received two HA 2% (40mg/2mL) injections (2mL) at one week apart. All of them have benefited of standardized rehabilitation, 3 times a week. Concerning the evaluation of the pathology, algo-functional tests (visual analogic scale (VAS), pressure algometer, IKDC score, VISA-P score), isokinetics (Cybex Norm; concentric 60°/s (C60), concentric 240°/s (C240) and eccentric 30°/s(E30)) associated to VAS, along with the patellar tendon ultrasonography (US) have been realized over three times (pre-injection, after 6 weeks, after 3 months post-injections). Results: The results of VAS (p<0,01), algometric scores (p<0,01), IKDC scores (p<0,01) and VISA-P (p<0,01) show a considerable improvement in the two groups, but not for the US findings. For the group 1 (Table 1), isokinetic tests show significant results for the hamstrings in C60°/s with an improvement of maximum peak torque (p=0,01) for the pathological limb, a diminution (p>0,05) for the healthy limb and during the analysis of the bilateral difference (p=0,0002). For the group 2, the improvement of quadriceps maximum peak torque in C240°/s is significant (p>0,01) for the pathological knee after 6 weeks post-injections only. The VAS associated with isokinetic tests decreases significantly for all contraction modes after three months of study. Conclusions: Both PRP and HA can improve the symptoms of proximal patellar tendinopathy, even if the results are slightly better in the PRP group. [less ▲]

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See detailMotion analysis: a prevention tool
Schwartz, Cédric ULg; CROISIER, Jean-Louis ULg; Forthomme, Bénédicte ULg et al

Conference (2017, April 28)

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See detailQuel « PRP » pour traiter les tendinopathies chroniques ?
Kaux, Jean-François ULg; Emonds-Alt, Thibault ULg

in Journal de Traumatologie du Sport (2017), 34(1), 76-90

Plasma rich platelets (PRP) consist of blood plasma with a high concentration of platelets autologous constituting a huge reservoir of growthfactors. The clinical use of the PRP is widespread in various ... [more ▼]

Plasma rich platelets (PRP) consist of blood plasma with a high concentration of platelets autologous constituting a huge reservoir of growthfactors. The clinical use of the PRP is widespread in various medical applications. Even it is very popular with athletes, the use of PRP intendinopathies is still scientifically discussed, particularly related to a disparity in the products called PRP. In order to optimize employment, itshould be interested in the different stages of obtaining of the PRP. In this literature review, we analyzed in particular 8 parameters that can influencethe quality of the PRP: (1) anticoagulants used to preserve the best feature of platelet; (2) centrifuge speeds used in order to extract platelets; (3)platelet concentrations and the presence of leukocytes and erythrocytes in the PRP; (4) the platelet activators for the mast of platelets and thus therelease of growth factors; (5) use of local anesthetics to achieve infiltration, in addition to these parameters, it might be interesting to analyze othervariables like: (6) employment or not of buffer to neutralize the acidity caused by anticoagulants; (7) injection under US guidance or not; and (8)volume of PRP injected to determine their influence on the healing potential. [less ▲]

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See detailImpact of an ultra-marathonof 330km on plasma levels of cardiac biomarkers
Le Goff, Caroline ULg; Kaux, Jean-François ULg; Gergelé, Laurent et al

in British Journal of Sports Medicine (2017, February), 51(4), 347

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See detailSelf-Administration of Medicines and Dietary Supplements Among Female Amateur Runners: A Cross-Sectional Analysis.
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Larbuisson, Robert ULg et al

in Advances in Therapy (2017), 33(12), 2257-2268

INTRODUCTION: Self-administration of medicines or dietary supplements without any physician's advice is a widespread behavior and appears to be more frequently practiced by women. Moreover, reasons to ... [more ▼]

INTRODUCTION: Self-administration of medicines or dietary supplements without any physician's advice is a widespread behavior and appears to be more frequently practiced by women. Moreover, reasons to self-administer products are often pains and injuries especially among athletes who might also use remedies to improve physical performance. The objective of this study was thus to assess the prevalence of self-administration of medicines and dietary supplements as well as its determinants among female amateur runners. METHODS: Our sample was comprised of women who took part in amateur running events. Data regarding self-administration of substances, exclusively aiming at being physically prepared for the running event (i.e., intake the week before), were collected through an anonymous self-administered questionnaire including four specific themes (i.e., general information, self-administered medicines and dietary supplements, context of self-administration of substances and knowledge of the anti-doping regulations). RESULTS: A total of 136 women, with a median age of 39 years (interquartile range: 27-47), volunteered. Among them, 34.6% reported self-administration of medicines during the period immediately preceding the running event, with the aim to be physically prepared. More than one third (33.8%) also declared self-administration of dietary supplements. Furthermore, we observed that about 8.1% of the sample had consumed a potentially doping substance. After adjustments for confounding variables, the probability of self-administration of products (medicines or supplements) increased significantly with the intensity of the activity and the membership in a sports club. CONCLUSIONS: Our study showed that self-administration of products among female runners seems to be a widespread behavior, where the intensity of the sports practice and the network of runners seem to influence the decision to resort to this behavior. [less ▲]

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See detailCoude - Poignet - Main
Kaux, Jean-François ULg

Learning material (2017)

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See detailAvulsion fracture of the ischial tuberosity in a young sprinter: conservative or surgical treatment?
Tyberghein, Maëlle; Kaux, Jean-François ULg; GODON, Bernard ULg et al

in Abstract Book of Annual Congress of Physical & Rehabilitation Medicine 2016 (2016, December 09)

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See detailIntracanalar lumbar neurinoma
Manto, Florence; HOUET, Elise ULg; LACREMANS, Pierre ULg et al

in Abstract Book of Annual Congress of Physical & Rehabilitation Medicine 2016 (2016, December 09)

Neurinoma are slow growing encapsulated tumors, coming from Schwann cells. They are a rare cause of low back pain, possibly with a radiating pain in the inferior limb. This case report describes the ... [more ▼]

Neurinoma are slow growing encapsulated tumors, coming from Schwann cells. They are a rare cause of low back pain, possibly with a radiating pain in the inferior limb. This case report describes the managing of a patient with right cruralgia without strength lost. The CT- scan had failed to highlight a lesion corresponding to the symptoms of the patient. A MRI was therefore realized, and was able to show a lumbar intradural tumor. The MRI signal of neurinoma is usually typical. However, in this case, the histo-pathological analysis has been necessary to confirm the diagnosis. The patient underwent laminectomy and tumor resection with nearly complete resolution of symptoms, excepting a right perineal hemihypoesthesia, probably corresponding to the location of the concerned nervous root. The MRI is the best method to explore cruralgia or a sciatica not responding to treatment, and without precipitating factor such as disc herniation explaining the symptoms. [less ▲]

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See detailRecurrent stress fracture of tibial tubercule in a volleyball player - a case report
SANFILIPPO, Damien ULg; Kaux, Jean-François ULg

in Abstract Book of Annual Congress of Physical & Rehabilitation Medicine 2016 (2016, December 09)

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See detailScapulothoracic bursitis and kyphoscoliosis: a case report
MILANTS, Christophe ULg; Kaux, Jean-François ULg

in Abstract Book of Annual Congress of Physical & Rehabilitation Medicine 2016 (2016, December 09)

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See detailCortical desmoid: Case Report and Literature Review
COLLIN, Romain ULg; Kaux, Jean-François ULg

in Abstract Book of Annual Congress of Physical & Rehabilitation Medicine 2016 (2016, December 09)

We describe a cortical desmoid lesion in a 13-year-old male football player. This case is the typical illustration of symptoms and radiological findings founded in cortical desmoid. Cortical desmoid is ... [more ▼]

We describe a cortical desmoid lesion in a 13-year-old male football player. This case is the typical illustration of symptoms and radiological findings founded in cortical desmoid. Cortical desmoid is benign cortical fibro-osseous lesion that most frequently occurs in the medial supracondylar femur. A traumatic pathogenesis of this lesion is the most probable cause due to higher traction forces at the insertion site of gastrocnemius or the aponeurosis of adductor magnus. It’s usually diagnosed in 10-15-year-old male adolescent who present knee pain, tenderness or swelling. It also can be asymptomatic and incidental finding on radiological exam. Radiologic features depend on the shape and the stage of lesion evolution. It is important to make a correct diagnosis to avoid many additional tests and biopsy, thinking it is a malignant bone tumor. Despite no published therapeutic guideline exists in literature, symptomatic treatment can be considered efficient. [less ▲]

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See detailCross-cultural adaptation and validation of the Patient-Rated Tennis Elbow Evaluation (PRTEE) questionnaire on lateral elbow tendinopathy for French-speaking patients
Kaux, Jean-François ULg; DELVAUX, François ULg; SCHAUS, Jean ULg et al

in Journal of Hand Therapy (2016), 29(4), 496-504

Background: The lateral elbow tendinopathy is a common injury in tennis players and physical workers. The Patient-Rated Tennis Elbow Evaluation (PRTEE) questionnaire was specifically designed to measure ... [more ▼]

Background: The lateral elbow tendinopathy is a common injury in tennis players and physical workers. The Patient-Rated Tennis Elbow Evaluation (PRTEE) questionnaire was specifically designed to measure pain and functional limitations in patients with lateral epicondylitis (tennis elbow). First developed in English, this questionnaire has since been translated into several languages. Objectives: The aims of the study were to translate and cross-culturally adapt the PRTEE questionnaire into French and to evaluate the reliability and validity of this translated version of the questionnaire (PRTEE-F). Methods: The PRTEE was translated and cross-culturally adapted into French according to international guidelines. To assess the reliability and validity of the PRTEE-F, 115 participants were asked twice to fill in the PRTEE-F, and once the Disabilities of Arm, Shoulder and Hand questionnaire (DASH) and the Short Form Health Survey (SF-36). Internal consistency (using Cronbach’s alpha), test-retest reliability (using intra-class correlation coefficient (ICC), Standard Error of Measurement (SEM) and Minimal Detectable Change (MDC)), and convergent and divergent validity (using the Spearman’s correlation coefficients respectively with the DASH and with some sub scales of the SF-36) were assessed. Results: The PRTEE was translated into French without any problems. PRTEE-F showed a good test-retest reliability for the overall score (ICC 0.86) and for each item (ICC 0.8-0.96) and a high internal consistency (Cronbach’s alpha = 0.98). The correlation analyses revealed high correlation coefficients between PRTEE-F and DASH (convergent validity) and, as expected, a low or moderate correlation with the divergent subscales of the SF-36 (discriminant validity). There was no floor or ceiling effect. Conclusions: The PRTEE questionnaire was successfully cross-culturally adapted into French. The PRTEE-F is reliable and valid for evaluating French-speaking patients with lateral elbow tendinopathy. [less ▲]

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See detailValidity and reliability of the French translation of the VISA-A questionnaire for Achilles tendinopathy
Kaux, Jean-François ULg; Delvaux, François ULg; Oppong-Kyei, Julian et al

in Disability & Rehabilitation (2016), 38(26), 2593-2599

Purpose The Victorian Institute of Sport Assessment – Achilles tendinopathy questionnaire (VISA-A) evaluates the clinical severity of Achilles tendinopathy. The aim of this study was to translate the VISA ... [more ▼]

Purpose The Victorian Institute of Sport Assessment – Achilles tendinopathy questionnaire (VISA-A) evaluates the clinical severity of Achilles tendinopathy. The aim of this study was to translate the VISA-A into French and to study the reliability and validity of this French version, the VISA-AF. Method The VISA-A was translated into French to produce the VISA-AF using a validated methodology in six steps. Thereafter, several psychometric properties of this French version such as test–retest reliability, internal consistency, construct validity and floor and ceiling effects were evaluated. Therefore, we recruited 116 subjects, distributed into 3 groups: pathological patients (n¼31), at-risk athletes (n¼63) and healthy people (n¼22). Results The final version of the VISAAF was approved by an expert committee. On a scale ranging from 0 to 100, the average scores of the VISA-AF obtained were 59 (± 18) for the pathological group, 99 (± 1) for the healthy group and 94 (± 7) for the at-risk group. The VISA-AF shows excellent reliability, low correlations with the discriminant subscales of the SF-36 and moderate correlations with the convergent subscales of the SF-36. Conclusions The French version of the VISA-A is equivalent to its original version and is a reliable and valid questionnaire for French-speaking patients with Achilles tendinopathy. [less ▲]

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See detailReturn to play after injection of PRP to treat tendinopathies
Kaux, Jean-François ULg

Conference (2016, November 26)

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See detailEntorse de cheville - Le traitement fonctionnel
Kaux, Jean-François ULg

Conference (2016, November 03)

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See detailCaractéristiques et évolution de la force après rééducation de la rupture de coiffe des rotateurs
Forthomme, Bénédicte ULg; Schwartz, Cédric ULg; MAHIEU, Xavier ULg et al

in Abstract Book des XVIIIèmes RENCONTRES ISOCINETIQUES MEDIMEX / ROTSCHILD (2016, November)

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See detailRécupération musculaire après plastie LCA : conséquences sur le retour au sport
Croisier, Jean-Louis ULg; Delvaux, François ULg; Kaux, Jean-François ULg et al

in Abstract Book des XVIIIèmes RENCONTRES ISOCINETIQUES MEDIMEX / ROTSCHILD (2016, November)

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See detailAre there biologic factors of good prognosis after a platelet rich plasma (PRP) injection for tendinopathies ?
Libertiaux, Vincent ULg; Sancerne, Audrey; LE GOFF, Caroline ULg et al

in Journal of Exercise, Sports & Orthopedics (2016), 3(2), 1-4

Background : The aims of this study were to evaluate the effect of a single PRP injection followed by a standardized reeducation protocol among patients suffering from different tendinopathies, but ... [more ▼]

Background : The aims of this study were to evaluate the effect of a single PRP injection followed by a standardized reeducation protocol among patients suffering from different tendinopathies, but otherwise healthy, and to determine the biomarkers that constitute good prognosis factors, if any. Methods : 48 patients suffering from different tendinopathies and refractory to conventional physiotherapy were treated with a single PRP injection. Prior to the injection, a blood sample was drawn and some biological parameters (glycemia, cholesterolemia,...) were measured. A pain assessment was then made using a Visual Analog Scale of pain (VAS) and a pressure algometer. The same assessment was carried out after 6 weeks and 12 weeks when possible. Results : There is an overall significant improvement in VAS score at the end of the 12 weeks follow- up. However, no correlation was found between the evolution of the clinical scores and the biological parameters measured. Conclusion: A PRP injection followed by a program of eccentric rehabilitation positively affects the algo-functional scores of patients with tendinopathies who were refractory to conventional physio- therapy, whatever the initial values of the measuured biological parameters. [less ▲]

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