References of "Gillet, Marie-Claire"
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See detailCytological effects of culture media conditioned B16 melanoma cells and 3T3 fibroblasts
Coucke, Paul; Siwek, B.; Gillet, Marie-Claire ULg et al

in Anticancer Research (1991), 11(2), 801-804

Cytotoxic soluble fractions (M.W.<1,000) were prepared from media conditioned by mixed cultures of 3T3 fibroblasts and B16 cells. The ultrastructural analyses of cells (B16 or 3T3) treated with these ... [more ▼]

Cytotoxic soluble fractions (M.W.<1,000) were prepared from media conditioned by mixed cultures of 3T3 fibroblasts and B16 cells. The ultrastructural analyses of cells (B16 or 3T3) treated with these fractions revealed in them mitochondria swelling, blebs, broken membranes and dead cells. [less ▲]

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See detailCytotoxic and mitogenic activities in culture media conditioned by mouse B16 melanoma cells and 3T3 fibroblasts
Siwek, Brigitte; Wauthy, Jacques ULg; Coucke, Paul et al

in Anticancer Research (1991), 11(2), 755-759

Cytotoxic (M.W.< 1000) and mitogenic (M.W.>10000) soluble factors are released into media conditioned by pure or mixed populations of mouse 3T3 fibroblasts and B16 melanoma cells cutivated in vitro. They ... [more ▼]

Cytotoxic (M.W.< 1000) and mitogenic (M.W.>10000) soluble factors are released into media conditioned by pure or mixed populations of mouse 3T3 fibroblasts and B16 melanoma cells cutivated in vitro. They are generally more active on B16 than on fibroblasts. [less ▲]

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See detailEffects of Strychnopentamine on Cells Cultured in Vitro
Quetin-Leclercq, J.; Gillet, Marie-Claire ULg; Angenot, Luc ULg et al

in Chemico-Biological Interactions (1991), 80(2), 203-16

This paper describes the powerful cytotoxic action exerted by strychnopentamine (SP), a dimeric indole alkaloid extracted from Strychnos usambarensis Gilg, on B16 melanoma cells and on non-cancer human ... [more ▼]

This paper describes the powerful cytotoxic action exerted by strychnopentamine (SP), a dimeric indole alkaloid extracted from Strychnos usambarensis Gilg, on B16 melanoma cells and on non-cancer human fibroblasts cultured in vitro. SP strongly inhibits cell proliferation and induces cell death at a relatively low concentration (less than 1 microgram/ml) after 72 h of treatment in the two lines. Incorporation of [3H]thymidine and [3H]leucine by B16 cells significantly decreases after only 1 h of treatment at 0.5 microgram/ml. SP induces the formation of dense lamellar bodies and vacuolization in the cytoplasm, intense blebbing at the cell surface and various cytological alterations leading to cell death. [less ▲]

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See detailEffects of metals on mouse B16 melanoma and 3T3 fibroblasts
Siwek, Brigitte; Bahbouth, E; Gillet, Marie-Claire ULg et al

Poster (1990, October)

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See detailEffects of FeSO4 on B16 melanoma cells differentiation and proliferation
Gillet, Marie-Claire ULg; Siwek, Brigitte; Pozzi, G. et al

in Anticancer Research (1990), 10(4), 1029-1033

The paper shows that FeS04 can increase or reduce B16 cell proliferation and melanogenesis. Vitamin C toxicity for B16 cells was reduced in the presence of FeSO4.

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See detailControl of B16 mealnoma cells differentiation and proliferation by CuSO4 and vitamin C
Gillet, Marie-Claire ULg; Siwek, Brigitte; Pozzi, G. et al

in Anticancer Research (1990), 10(2A), 391-405

The paper demonstrates that the toxicity of CuSO4 in B16 melanoma cells is increased in serum-free medium and in the presence of Vitamin C. Vitamin C toxicity for B16 cells was increased in the presence ... [more ▼]

The paper demonstrates that the toxicity of CuSO4 in B16 melanoma cells is increased in serum-free medium and in the presence of Vitamin C. Vitamin C toxicity for B16 cells was increased in the presence of CUS04. [less ▲]

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See detailToxic and mitogenic activities of culture media conditioned by B16 melanoma cells
Coucke, Paul; Siwek, Brigitte; Gillet, Marie-Claire ULg et al

Conference (1990)

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See detailIdentification of cytotoxic factors in media conditioned by mouse B16 melanoma cells
Siwek, Brigitte; Gillet, Marie-Claire ULg; Sabbioni, Enrico et al

in Anticancer Research (1990), 10(5B), 1390

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See detailAntimitotic and cytotoxic Activities of Guattegaumerine, a Bisbenzylisoquinoline Alkaloid
Quetin-Leclercq, Joëlle; Gillet, Marie-Claire ULg; Bassleer, Roger et al

in Planta Medica (1987), 53

Guattegaumerine was isolated from the bark of Guatteria gaumeri ( cf Dehaussy, Tits and Angenot, Planta Med. (1983) 49, 25-27) , a medicinal plant called Yumel in Yucatan (South Mexico).Guattegaumerine ... [more ▼]

Guattegaumerine was isolated from the bark of Guatteria gaumeri ( cf Dehaussy, Tits and Angenot, Planta Med. (1983) 49, 25-27) , a medicinal plant called Yumel in Yucatan (South Mexico).Guattegaumerine exerts a good activity at 5 micrograms/ml on B16 melanoma which is a relatively resistant tumor. It is less active against 2002 cells that are normal human cells. [less ▲]

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See detailEffects of copper sulfate given alone or with alpha-MSH and L-tyrosine on B16 melanoma cells cultured in serum-free media.
Gillet, Marie-Claire ULg; wang, François; Simonon, A. et al

in Archives of Biology (1987), 98(3), 327-39

This study shows that copper sulphate (0.1mM) has antiproliferative effects in B16 melanoma cells cutured in various serum-free media.

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See detailLe mélanome B16 de la souris en culture à trois dimensions
Gillet, Marie-Claire ULg; Christiane, Y.; Foidart, Jean-Michel ULg et al

in Bulletin de l'Association des Anatomistes (1986), 70(210), 21-4

Multicellular spheroids composed of mouse B16 melanoma cells have been prepared in non agitated culture on solid agar. Cells present frequent contacts and an extracellular matrix appears during ... [more ▼]

Multicellular spheroids composed of mouse B16 melanoma cells have been prepared in non agitated culture on solid agar. Cells present frequent contacts and an extracellular matrix appears during cultivation (up to 2 months in agitated suspension); it contains laminin, fibronectin and collagen I, III and IV. Cellular differentiation takes place inside these spheroids (melanogenesis progressively increases), but a relatively intense cell proliferation rate is also maintained. [less ▲]

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See detailEtude de la matrice extracellulaire dans des sphéroïdes multi-cellulaires de mélanome B16 en culture
Gillet, Marie-Claire ULg; Vanstichel, Sabine; Bassleer, Roger

Poster (1986, May)

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See detailOur research program in neurobiology and experimental cancerology
Bassleer, Roger; Moonen, Gustave ULg; Gillet, Marie-Claire ULg et al

Conference (1986, April)

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See detailCo-cultures of mouse B16 melanoma cells and 3T3 fibroblasts in three dimensions
Gillet, Marie-Claire ULg; Dequinze, Benoit; Borlon, Anne et al

in European Journal of Cell Biology. Supplement (1986), 42(Suppl 15), 49

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See detailScreening of cytotoxic activities of Strychnos alkaloids ( methods and results)
Leclercq, Joëlle; Gillet, Marie-Claire ULg; Bassleer, Roger et al

in Journal of Ethnopharmacology (1986), 15

The potential cytotoxic activities of 46 alkaloids isolated from different Strychnos species were tested on different cancer or normal cells cultured in vitro. The authors use a relatively simple ... [more ▼]

The potential cytotoxic activities of 46 alkaloids isolated from different Strychnos species were tested on different cancer or normal cells cultured in vitro. The authors use a relatively simple microtest which gives good reproducibility. Most of the active compounds belong to the usambarane skeleton but other structure-activity relationships are being discussed. [less ▲]

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See detailQuantitative cytochemical analysis by microdensitometry of spontaneous or alpha-MSH-stimulated melanogenesis in B16 melanoma cells cultivated in vitro
Gillet, Marie-Claire ULg; Hennet, Jacques; Bassleer, Roger

in European Journal of Cancer & Clinical Oncology (1985), 21(8), 951-956

Spontaneous and alpha-MSH stimulated melanogenesis has been studied in B16 cells by densitometry. De novo synthesis of the enzyme dopa-oxydase takes place following alpha-MSH treatment.

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See detailControl of proliferation and differentiation in B16 melanoma cells in bi- or tridimensional cultures
Bassleer, Roger; Gillet, Marie-Claire ULg; Simonon, Anne et al

Poster (1985, May)

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See detailMechanism of action of free or incorporated into liposomes cis-DDPt : a comparative study in Ehrlich tumour cells
Gillet, Marie-Claire ULg; Houssier, Claude ULg; weber, georges et al

in Hacher, M. P.; Douple, F. B.; Krakoff, I. M. (Eds.) Platinum Coordination Complexes in Cancer Chemotherapy (1984)

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