References of "Giet, Didier"
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See detailEffect of different contraceptive methods on the oxidative stress status in women aged 40-48 years from the ELAN study in the province of Liege, Belgium
Pincemail, Joël ULg; Vanbelle, Sophie ULg; Gaspard, Ulysse ULg et al

in Human Reproduction (2007), 22(8), 2335-2343

Oxidative stress is associated with the development of several disorders including cardiovascular disease and cancer. Among conditions known to influence oxidative stress, the use of oral contraception ... [more ▼]

Oxidative stress is associated with the development of several disorders including cardiovascular disease and cancer. Among conditions known to influence oxidative stress, the use of oral contraception (OC) in women has been a matter of ongoing discussion. METHODS: A total of 897 eligible and healthy volunteers were recruited from among the patients of 50 general practitioners participating in the ELAN study (Etude Liegeoise sur les ANtioxydants). A subsample consisting of 209 women aged 40-48 years was studied for a comprehensive oxidative stress status (OSS), including the analysis of antioxidants, trace elements and three markers of oxidative damage to lipids. Among 209 subsample, 49 (23%) were OC users (OCU), 119 (57%) non-contraception users (NCU) and 41 (20%) were intrauterine (hormonal and copper) devices users (IUD). RESULTS: After adjustment for smoking, systolic and diastolic blood pressure and BMI (or waist circumference), a marked and significant increase in lipid peroxides was observed among OCU women when compared with NCU and IUD users. A cut-off value of 660 mu M in lipid peroxides allowed the discrimination of OCU from the two other groups. In contrast, no difference was observed in the plasma concentration of both oxidized low-density lipoprotein (LDL) and their related antibodies. The increased level in lipid peroxides was strongly related to higher concentrations of copper (r < 0.84; P < 0.0001, cut-off value 1.2 mg/1). When compared with NCU and IUD users, plasma antioxidant defences were significantly altered in OCU women as shown by lower levels of beta-carotene (decrease of 39%; P < 0.01) andytocopherol (decrease by 22%; P < 0.01). In contrast, higher concentrations of selenium (increased by 11.8%; P < 0.01) were observed in OCU women. Blood concentrations of vitamin C, alpha-tocopherol and zinc were unaffected by OC use. CONCLUSIONS: The intake of OC significantly increases the lipid peroxidation in women aged 40-48 years. This may represent a potential cardiovascular risk factor for these women. [less ▲]

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See detailTest de Concordance de Script: un nouveau mode d’établissement des scores limitant l’effet du hasard
Vanbelle, Sophie ULg; Massart, Valérie ULg; Giet, Didier ULg et al

in Pédagogie médicale (2007), 8

Context: The method of combined scores is currently used to determine the score obtained by the Script Concordance Test (SCT). Goal: To propose a novel measure of agreement between the SCT responses given ... [more ▼]

Context: The method of combined scores is currently used to determine the score obtained by the Script Concordance Test (SCT). Goal: To propose a novel measure of agreement between the SCT responses given by the candidate and those provided by the panel of experts. Results: The current scoring method of the SCT does not take into account the fact that agreement between the candidate and the panel of experts may be arbitrary. The proposed measure allows correcting this fact. Conclusion: This article addresses the problem of scores obtained by guessing. The new measure of agreement allows to improve the actual scoring method. [less ▲]

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See detailMaltraitance des Aînés : ressentis et besoins de professionnels de soins à domicile
Vanmeerbeek, Marc ULg; Massart, Valérie ULg; Giet, Didier ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2007), 55

A la demande du Centre d’Aide aux Personnes Agées Maltraitées (CAPAM), le Département de Médecine Générale de l’Université de Liège a mené une recherche qualitative portant sur la maltraitance des aînés à ... [more ▼]

A la demande du Centre d’Aide aux Personnes Agées Maltraitées (CAPAM), le Département de Médecine Générale de l’Université de Liège a mené une recherche qualitative portant sur la maltraitance des aînés à domicile. Cette étude avait pour objectif d’analyser le ressenti, en matière de maltraitance des personnes âgées, de professionnels de la santé de trois disciplines intervenant fréquemment au domicile : médecins généralistes, aides familiales et infirmier(e)s. Pour chaque profession, une trentaine de représentants issus de pratiques variées (urbaines et rurales ; salariés et indépendants ; etc.) ont été sélectionnés et répartis en trois focus groups (groupes de discussion semi-structurés encadrés par un animateur) . La transcription intégrale du contenu des discussions a servi de base à l’analyse de contenu. Un guide d’entretien a été construit au départ des questions de recherche suivantes : Comment les professionnels de la santé concernés définissent-ils la maltraitance des personnes âgées ? Dans quel contexte la rencontrent-ils éventuellement ? Quels sont les signes qui peuvent leur faire suspecter cette maltraitance ? Quels rôles pensent-ils avoir et de quelle(s) manière(s) agissent-ils ? Quelles difficultés rencontrent-ils face à une situation de maltraitance à domicile ? Quels sont leurs besoins pour y faire face efficacement ? Quelles pistes d’action pourraient être apportées à cette problématique à un niveau sociétal ? [less ▲]

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See detailLe dosage de l'homocystéine intéresse-t-il le Médecin généraliste ?
Girs, Noella; Giet, Didier ULg

in Revue Médicale de Liège (2006), 61(5-6), 352-361

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See detailEditorial 2006 : le RMLg entre dans la 7e décénnie
Kulbertus, Henri ULg; Giet, Didier ULg

in Revue Médicale de Liège (2006), 61(1), 1-2

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See detailConseils pour une meilleure prescription medicamenteuse.
Scheen, André ULg; Parada, Alberto; Giet, Didier ULg

in Revue Médicale de Liège (2006), 61(5-6), 488-93

The prescription of a pharmacological agent concludes most medical visits. The rational basis of drug prescription by the physician relies on numerous pharmacodynamic, pharmacokinetic, pragmatic and ... [more ▼]

The prescription of a pharmacological agent concludes most medical visits. The rational basis of drug prescription by the physician relies on numerous pharmacodynamic, pharmacokinetic, pragmatic and economic considerations. However, it is a pity to notice that one patient out of two does not strictly follow the pharmacological treatment as it was prescribed. This article analyses some problems of the patient-doctor relationship, which may reduce medication compliance, and provides practical advice for improving such a situation in order to enhance both efficacy and safety of drug prescribing. [less ▲]

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See detailDix sites Internet d'usage frequent en medecine generale
Sepulchre, Christophe; Bouniton, Marc ULg; Collette, Georges ULg et al

in Revue Médicale de Liège (2006), 61(5-6), 520-37

Internet use is booming worldwide. The general practitioner can find on the Web a significant help for his research of information, as well as for his medical practice and the administrative management of ... [more ▼]

Internet use is booming worldwide. The general practitioner can find on the Web a significant help for his research of information, as well as for his medical practice and the administrative management of his office. The proportion of general practitioners who make use of Internet in their professional life is constantly increasing, but their major difficulty remains to know where to quickly find the reliable information. The purpose of this paper is to describe ten Websites of particular interest in general practice. [less ▲]

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See detailMise au point d'une hyperferritinémie
Delwaide, Jean ULg; Giet, Didier ULg; Lamproye, Anne ULg et al

in Revue Médicale de Liège (2006), 61(5-6), 329-333

Hemochromatosis is the most common genetic disorder in persons of northern European descent, and the majority of cases are caused by a mutation in the gene HFE. Genetic testing for hemochromatosis is ... [more ▼]

Hemochromatosis is the most common genetic disorder in persons of northern European descent, and the majority of cases are caused by a mutation in the gene HFE. Genetic testing for hemochromatosis is therefore indicated in all patients with increases in transferrine saturation and ferritin levels. When this genetic testing does not demonstrate a hemochromatosis, other diseases responsible for elevated ferritin levels have to be ruled out, mainly hemolytic anemia, chronic inflammatory disorders, liver diseases such as hepatitis B or C, alcohol abuse, and non alcoholic fatty liver disease. In demonstrated iron overload with absence of classic causes, second-line genetic testing should be considered. [less ▲]

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See detailMedecin de famille et intoxication au monoxyde de carbone
Burette, Philippe ULg; Bouüaert, Corine ULg; Vanmeerbeek, Marc ULg et al

in Revue Médicale de Liège (2006), 61(5-6, May-Jun), 285-90

Carbon monoxide poisoning is not easily identifiable. It is the first cause of death by accidental poisoning in Europe. The family practitioner, who has not been made aware of this problem, incurs the ... [more ▼]

Carbon monoxide poisoning is not easily identifiable. It is the first cause of death by accidental poisoning in Europe. The family practitioner, who has not been made aware of this problem, incurs the risk of diagnostic indecision or of involuntary personal poisoning. Since symptomatology is non specific, the general practitioner answering housecalls is sometimes confronted with an urgent medical problem linked to the complications of this intoxication (coronary, neurological problems...), without having ways of documenting its origin of the poisoning or any means to protect himself. Through direct contact with his patients' environment, the family practitioner, being made sensitive to this problem, can certainly contribute to care and aftercare of the patient suffering from carbon monoxide poisoning, but also to the prevention of this public health problem often called "the silent killer". [less ▲]

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See detailApproche de la complexité contextuelle et de la pluridisciplinarité de l'action médicale : mise en place de séances d'Apprentissage à la résolution de Problèmes complexes (ARPc) en fin de 2ème cycle d'études médicales
Giet, Didier ULg; Massart, Valérie ULg; Stir, Arielle et al

in Pédagogie Médicale (2005), (6), 88-97

Contexte: La formation des futurs médecins doit prendre en compte la portée éthique, socio-environnementale, économique, juridique et psychologique de l’action médicale ainsi que ses aspects ... [more ▼]

Contexte: La formation des futurs médecins doit prendre en compte la portée éthique, socio-environnementale, économique, juridique et psychologique de l’action médicale ainsi que ses aspects pluridisciplinaires. Dans le cadre d’un renouveau pédagogique décidé en Faculté de Médecine de l’Université de Liège, une modalité particulière de l’apprentissage par problèmes, les séances d’Apprentissage à la Résolution de Problèmes complexes (ARPc), a été instaurée. Buts : Les auteurs rapportent la méthodologie spécifique, étayée par des exemples concrets, développée lors de l’instauration des séances d’ARPc ainsi que les premières analyses d’une procédure d’évaluation qualitative. Sujet : Le dispositif s’adresse aux étudiants des deux dernières années du 2e cycle de formation médicale. Les objectifs pédagogiques spécifiques des ARPc sont l’approche de la complexité contextuelle de toute pratique médicale et l’initiation au travail pluridisciplinaire. Résultats : Les premières procédures d’évaluation qualitatives ciblant étudiants et enseignants donnent des résultats assez favorables. Conclusion : L’expérience est poursuivie moyennant quelques aménagements organisationnels mineurs. Elle s’ouvre à d’autres disciplines médicales et fait l’objet d’une évaluation quantitative à publier ultérieurement. [less ▲]

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See detailPrevention du diabete de type 2: un nouveau defi de sante publique.
Scheen, André ULg; Giet, Didier ULg

in Revue Médicale de Liège (2005), 60(5-6), 383-90

Owing to the epidemics of type 2 diabetes, it is important to develop strategies of prevention of the disease. The first step should detect patients at risk, in function of simple anamnesis, clinical and ... [more ▼]

Owing to the epidemics of type 2 diabetes, it is important to develop strategies of prevention of the disease. The first step should detect patients at risk, in function of simple anamnesis, clinical and biological criteria. Afterwards, those individuals should be encouraged to follow a prevention programme, which essentially comprises better lifestyle habits (diet and physical exercise), especially to prevent or correct weight excess. In at very high risk subjects, for instance because of moderately increased fasting or post-glucose load glucose levels, eventually in a context of family history of type 2 diabetes, a pharmacological approach could be considered. Various drugs (metformin, acarbose, glitazones, orlistat, inhibitors of the renin-angiotensin system) have proven their efficacy in reducing the incidence of type 2 diabetes, in particular in individuals with impaired glucose tolerance, with obesity and/or with arterial hypertension. [less ▲]

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See detailGPs working in solo practice : obstacles and motivations for working in a group ? A qualitative study
Feron, Jean-Marc; Cerexhe, F.; Pestiaux, Dominique et al

in BMC Family Practice (2003), 20(2), 167-172

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See detailLa melanogenese, expression de la differenciation de cellules cancereuses en culture
Bassleer, Roger; Gillet, Marie-Claire ULg; Giet, Didier ULg et al

in Bulletin de l'Association des Anatomistes (1982), 66(194), 291-295

In B16 mouse melanoma in culture, differentiated cells actively synthesize melanin. They are analyzed by cytological and cytochemical methods. When cultured for long periods (several months ... [more ▼]

In B16 mouse melanoma in culture, differentiated cells actively synthesize melanin. They are analyzed by cytological and cytochemical methods. When cultured for long periods (several months), melanogenesis is expressed according to a cyclic way, even when maintained in a culture medium of constant composition and without adding any chemical agent eventually able to influence this phenomenon. The spontaneous cyclic activity is analyseed and an explanation is given as an hypothesis. [less ▲]

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