References of "Ghuysen, Alexandre"
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See detailELISA : ECHELLE LIÉGEOISE DE L’INDICE DE SÉVÉRITÉ À L’ADMISSION
JOBE, Jérôme ULg; Ghuysen, Alexandre ULg; D'Orio, Vincenzo ULg

in Revue Médicale de Liège (2012), 67(12), 632-637

Les services d’urgence sont régulièrement confrontés au problème d’encombrement à l’admission par une demande qui dépasse l’offre de soins. Il est essentiel de réguler le flux d’entrée par la mise en ... [more ▼]

Les services d’urgence sont régulièrement confrontés au problème d’encombrement à l’admission par une demande qui dépasse l’offre de soins. Il est essentiel de réguler le flux d’entrée par la mise en place d’un dispositif de tri. Ce mécanisme s’affine depuis une quinzaine d’années. Nous proposons un algorithme de tri (ELISA ou Echelle Liégeoise de l’Indice de Sévérité à l’Admission) qui vise à définir l’état d’urgence selon 5 niveaux depuis la catégorie U1 (urgence absolue) à U5 (urgence relative). Ces niveaux sont associés à un délai de contact médical (immédiat à 120 minutes) et à un trajet de soin correspondant (salle de déchoquage, secteur B ou brancard, secteur A ou ambulatoire, salle d’attente) réunissant ainsi des impératifs de temps et de lieu de prise en charge optimaux. Notre algorithme de tri montre une excellente fiabilité par la comparaison du niveau initial de la catégorisation au devenir du patient (soins intensifs, hospitalisation, et sortie du service). [less ▲]

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See detailEstimating afterload, systemic vascular resistance and pulmonary vascular resistance in an intensive care setting
Stevenson, D; Revie, J.; Chase, JG et al

in Proceedings of BMS2012 (2012)

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See detailModel-based Monitoring of Septic Shock Treated with Large-Pore Hemofiltration Therapy
Revie; Stevenson, D; Chase, JG et al

in Proceedings of BMS 2012 (2012)

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See detailAnalysis of Aortic Energetics from Pulse Wave Examination in a Porcine Study of Septic Shock
Revie, JA; Stevenson, D; Chase, JG et al

in Prceedings of BMS 2012 (2012)

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See detailAlgorithmic Processing of Pressure Waveforms to FacilitateEstimation of Cardiac Elastance
Stevenson, D.; Revie, J.; Chase, J. G. et al

in BioMedical Engineering OnLine (2012), 11

Introduction: Cardiac elastances are highly invasive to measure directly, but are clinically useful due tothe amount of information embedded in them. Information about the cardiac elastance, which can be ... [more ▼]

Introduction: Cardiac elastances are highly invasive to measure directly, but are clinically useful due tothe amount of information embedded in them. Information about the cardiac elastance, which can be used toestimate it, can be found in the downstream pressure waveforms of aortic pressure (Pao) and the pulmonaryartery (Ppa). However these pressure waveforms are typically noisy and biased, and require processing in orderto locate the specific information required for the cardiac elastance estimation. This paper presents the methodto algorithmically process the pressure waveforms. Methods: A shear transform is developed in order to helplocate information in the pressure waveforms. This transform turns difficult to locate corners into easy to locatemaximum or minimum points as well as providing error correction. Results: The method located all points 87out of 88 waveforms for Ppa to within the sampling frequency. For Pao, out of 616 total points, 605 were foundwithin 1%, 5 within 5%, 4 within 10% and 2 within 20%. Conclusions: The presented method provides arobust, accurate and dysfunction independent way to locate points on the aortic and pulmonary artery pressurewaveforms, allowing the non-invasive estimation of the left and right cardiac elastance. [less ▲]

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See detailBeat-to-beat estimation of the continuous left and right cardiac elastance from metrics commonly available in clinical settings.
Stevenson, David; Revie, James; Chase, J. Geoffrey et al

in BioMedical Engineering OnLine (2012), 11(1), 73

ABSTRACT: INTRODUCTION: : Functional time-varying cardiac elastances (FTVE) contain a rich amount of information about the specific cardiac state of a patient. However, a FTVE waveform is very invasive to ... [more ▼]

ABSTRACT: INTRODUCTION: : Functional time-varying cardiac elastances (FTVE) contain a rich amount of information about the specific cardiac state of a patient. However, a FTVE waveform is very invasive to directly measure, and is thus currently not used in clinical practice. This paper presents a method for the estimation of a patient specific FTVE, using only metrics that are currently available in a clinical setting. METHOD: : Correlations are defined between invasively measured FTVE waveforms and the aortic and pulmonary artery pressures from 2 cohorts of porcine subjects, 1 induced with pulmonary embolism, the other with septic shock. These correlations are then used to estimate the FTVE waveform based on the individual aortic and pulmonary artery pressure waveforms, using the "other" dysfunction's correlations as a cross validation. RESULTS: : The cross validation resulted in 1.26% and 2.51% median errors for the left and right FTVE respectively on pulmonary embolism, while the septic shock cohort had 2.54% and 2.90% median errors. CONCLUSIONS: : The presented method accurately and reliably estimated a patient specific FTVE, with no added risk to the patient. The cross validation shows that the method is not dependent on dysfunction and thus has the potential for generalisation beyond pulmonary embolism and septic shock. [less ▲]

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See detailA medieval shot
LOMBARD, Xavier ULg; Ghuysen, Alexandre ULg; D'Orio, Vincenzo ULg

Poster (2012)

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See detailBlue... is a bad sign
LORCE, Aurélie ULg; BODSON, Lucien ULg; Ghuysen, Alexandre ULg et al

Poster (2012)

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See detailEfficiency of elisa : a new french-language triage algorithm
JOBE, Jérôme ULg; Ghuysen, Alexandre ULg; Gerard, P. et al

in Acta Clinica Belgica (2011)

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See detailTraining on the alert phone CPR protocol in belgium : evaluation of the dispatchers
El Fassi, Mehdi; Skivee, V.; STIPULANTE, Samuel ULg et al

in Acta Clinica Belgica (2011), 66(2), 9

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See detailDispatcher-assisted telephone cardiopulmonary resuscitation using a French-language compression-only protocol in volunteers with or without prior life support training: A randomized trial.
Ghuysen, Alexandre ULg; Collas, D.; Stipulante, Samuel ULg et al

in Resuscitation (2011)

OBJECTIVES: Due to the recent interest in hands-only protocols for dispatcher-assisted cardiopulmonary resuscitation (CPR) and the lack of any validated algorithms in French, our primary objective was to ... [more ▼]

OBJECTIVES: Due to the recent interest in hands-only protocols for dispatcher-assisted cardiopulmonary resuscitation (CPR) and the lack of any validated algorithms in French, our primary objective was to evaluate a new French-language protocol in terms of its efficacy to help previously untrained volunteers in performing basic life support efforts of appropriate quality, and secondarily to investigate its potential utility in subjects with previous training. METHODS: Untrained volunteers were recruited among adults in a public movie centre and previously trained volunteers among undergraduate nursing students. Participants were randomly assigned to 'phone CPR' versus 'no phone CPR' by drawing sets of envelopes. Primary outcome measures were the results of the Cardiff evaluation test; the secondary measures were global scoring of a complete 5min period of CPR, in a manikin model of cardiac arrest. RESULTS: Out of 146 volunteers assessed for eligibility, 36 previously untrained candidates declined participation. 110 participants, distributed into four groups, completed the study: the previously untrained non-guided group (group A, n=30), the previously untrained guided group (group B, n=30), the previously trained non-guided group (group C, n=25) and the previously trained guided group (group D, n=25). Results of the Cardiff test and global evaluation of CPR performance revealed a significant improvement in group B as compared with group A, approaching the level of the group C. Previously trained guided bystanders had the best CPR scores, notably because of an improvement in the quality of airway management. CONCLUSION: When used by dispatchers, this new French-language algorithm offers the opportunity to help previously untrained bystanders initiate CPR. The same protocol may serve to guide volunteers with prior basic life support training to reach their best CPR performance. [less ▲]

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See detailModel-based cardiovascular monitoring of acute pulmonary embolism in porcine trials
Revie, JA; Stevenson, DJ; Chase, JG et al

in Critical Care (2011), 15 (Suppl 1)

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See detailModel-based cardiovascular monitoring of large pore hemofiltration during endotoxic shock in pigs
Revie, JA; Stevenson, DJ; Chase, JG et al

in Critical Care (2011), 15 (Suppl 1)

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See detailPatient specific identification of the cardiac driver function in a cardiovascular system model.
Hann, C. E.; Revie, J.; Stevenson, D. et al

in Computer Methods & Programs in Biomedicine (2011)

The cardiac muscle activation or driver function, is a major determinant of cardiovascular dynamics, and is often approximated by the ratio of the left ventricle pressure to the left ventricle volume. In ... [more ▼]

The cardiac muscle activation or driver function, is a major determinant of cardiovascular dynamics, and is often approximated by the ratio of the left ventricle pressure to the left ventricle volume. In an intensive care unit, the left ventricle pressure is usually never measured, and the left ventricle volume is only measured occasionally by echocardiography, so is not available real-time. This paper develops a method for identifying the driver function based on correlates with geometrical features in the aortic pressure waveform. The method is included in an overall cardiovascular modelling approach, and is clinically validated on a porcine model of pulmonary embolism. For validation a comparison is done between the optimized parameters for a baseline model, which uses the direct measurements of the left ventricle pressure and volume, and the optimized parameters from the approximated driver function. The parameters do not significantly change between the two approaches thus showing that the patient specific approach to identifying the driver function is valid, and has potential clinically. [less ▲]

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