References of "Gabriel, Annick"
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See detailLes tendinopathies et desmopathies des régions métacarpienne et –tarsienne: revue des thérapies actuelles. Seconde partie : les traitements
Verwilghen, Denis ULg; Caudron, Isabelle; Van Galen, Gaby ULg et al

in Annales de Médecine Vétérinaire (2010), 154(1), 1-15

Lesions to the horse’s tendon are very frequent and are a non negligible reason for early retirement of sport and leisure horses. For decades man has been searching for “the” treatment but unfortunately ... [more ▼]

Lesions to the horse’s tendon are very frequent and are a non negligible reason for early retirement of sport and leisure horses. For decades man has been searching for “the” treatment but unfortunately most of the known treatments have empiric bases and very few have actually proven their real efficiency. Diagnostic techniques like ultrasound allows to better evaluate the improvements made in tendonitis therapies. Stem cells and gene therapy are probably the most innovating of them, but their long-term effectiveness still has to stand the test of times. This article gives an overview of the possible treatments of tendonitis today. [less ▲]

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See detailMorphological and histological studies of sheep’s brain
Salouci, Moustafa ULg; Engelen, Virginie; Jacqmot, Olivier ULg et al

Poster (2010)

Introduction: The study of normal structures of the sheep’s brain is very important to understand pathological changes caused by the bluetongue virus in the fetus’s brain at various stages of the ... [more ▼]

Introduction: The study of normal structures of the sheep’s brain is very important to understand pathological changes caused by the bluetongue virus in the fetus’s brain at various stages of the gestation. Bluetongue is an arthropod-borne viral disease of domestic and wild ruminants. The serotype 8 is responsible for outbreaks in Northern Europe in 2006. This virus causes lesions in the brain of fetuses as hydrancephaly and porencephaly. The aim of this work is to improve knowledge of anatomy and histology of the central nervous system of the sheep. Methods: Seven heads of adult sheep and one from a fetus aged 4,5 months were used. All heads were first opened in the frontal area using bone’s saw and immerged in a formalin solution for 10 days. After a good fixation, the brains were extracted and sectioned. Transversal, frontal and sagittal sections were realized. The sections of two brains were stained with Berlin-blue and treated to be embedded in methylmetacrylate for gross morphology. The different parts of the 6 resting brains were then embedded in paraffin, cut and the histological sections were stained with haematoxylin/eosin, cresyl violet or by use of silver impregnation. Results: Gross morphological examination of the brains embedded in methylmetacrylate showed the detailed anatomy of the different parts. The staining with haematoxylin/eosin permitted to differentiate the grey matter, the different nucleus and the layers of cerebral and cerebellum cortex. The cresyl violet technique permitted to visualize the Nissl bodies and the silver impregnation revealed nerve fibers. In the fetus brain, blood vessels were very numerous in the brainstem, the cerebellum and the cerebrum. The grey matter was less organized and looser. Conclusion: This work establishes an anatomical and histological approach allowing future studies in ovine fetuses with and without brain lesions potentially caused by the bluetongue virus. [less ▲]

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See detailBone Turnover During Pregnancy in Horses
Greiner, Claudia; Cavalier, Etienne ULg; Remy, Benoit et al

in Journal of Bone and Mineral Research (2010), 25

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See detailLes tendinopathies et desmopathies de la région métacarpienne et –tarsienne: une revue des thérapies actuelles. Première partie : la structure, les lésions du tendon et le diagnostic.
Verwilghen, Denis ULg; Gabriel, Annick ULg; Busoni, Valeria ULg et al

in Annales de Médecine Vétérinaire (2009), 3(153), 145-155

Lesions to the horse’s tendon are very frequent and are a non negligible reason for early retirement of sport and leisure horses. For decades man has been searching for “the” treatment but unfortunately ... [more ▼]

Lesions to the horse’s tendon are very frequent and are a non negligible reason for early retirement of sport and leisure horses. For decades man has been searching for “the” treatment but unfortunately most of the known treatments have empiric bases and very few have actually proven their real efficiency. Better knowledge of tendon anatomy and pathophysiology of tendonitis together with evolutions in diagnostic techniques like ultrasonography allows us to better evaluate the improvements made in tendonitis therapies today. The first part of this article gives a review on tendon structure, tendon healing and ultrasonographic evaluation of the tendon. In the second part an overview of therapeutic options for tendonitis will be discussed. [less ▲]

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See detailVascularisation of the equine menisci
De Busscher, V.; Maitre, D.; Busoni, Valeria ULg et al

Poster (2009)

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See detailExamen échographique de l'encolure chez le cheval
Busoni, Valeria ULg; Heinen, Marie-Pierre ULg; Gabriel, Annick ULg

in Pratique Vétérinaire Equine Numéro Spécial: Pathologie du rachis chez les équidés (2008)

This paper illustrates the application of ultrasonography to the assessment of the equine neck and describe technique and normal and abnormal ultrasonographic findings. Interventional procedures are also ... [more ▼]

This paper illustrates the application of ultrasonography to the assessment of the equine neck and describe technique and normal and abnormal ultrasonographic findings. Interventional procedures are also briefly described. [less ▲]

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See detailMagnetic resonance imaging arteriography of canine normal brain: an anatomic study
Jacqmot, Olivier ULg; Hoffmann, A. C.; Bustin, P. H. et al

Poster (2008)

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See detailDo tonsilar FDCs express PrPc in sheep?
Toppets, Vinciane ULg; Piret,J; Minne,M et al

Poster (2007, October)

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See detailNeuroimmune connections in jejunal and ileal Peyer's patches at various bovine ages: potential sites for prion neuroinvasion
Defaweux, Valérie ULg; Dorban, Gauthier ULg; Antoine, Nadine ULg et al

in Cell & Tissue Research (2007), 329(1), 35-44

During preclinical stages of cattle orally infected with bovine spongiform encephalopathy (BSE), the responsible agent is confined to ileal Peyer's patches (IPP), namely in nerve fibers and in lymph ... [more ▼]

During preclinical stages of cattle orally infected with bovine spongiform encephalopathy (BSE), the responsible agent is confined to ileal Peyer's patches (IPP), namely in nerve fibers and in lymph follicles, before reaching the peripheral and central nervous systems. No infectivity has been reported in other bovine lymphoid organs, including jejunal Peyer's patches (JPP). To determine the potential sites for prion neuroinvasion in IPP, we analyzed the mucosal innervation and the interface between nerve fibers and follicular dendritic cells (FDC), two dramatic influences on neuroinvasion. Bovine IPP were studied at three ages, viz., newborn calves, calves less than 12 months old, and bovines older than 24 months, and the parameters obtained were compared with those of JPP. No differences in innervation patterns between IPP and JPP were found. The major difference observed was that, in calves of less than 12 months, IPP were the major mucosal-associated lymphoid organ that possessed a large number of follicles with extended FDC networks. Using a panel of antibodies, we showed that PP in 24-month-old bovines were highly innervated at various strategic sites assumed to be involved in the invasion and replication of the BSE pathogen: the suprafollicular dome, T cell area, and germinal centers. In PP in calves of less than 12 months old, no nerve fibers positive for the neurofilament markers NF-L (70 kDa) and NF-H (200 kDa) were observed in contact with FDC. Thus, in view of the proportion of these protein subunits present in neurofilaments, the innervation of the germinal centers can be said to be an age-dependent dynamic process. This variation in innervation might influence the path of neuroinvasion and, thus, the susceptibility of bovines to the BSE agent. [less ▲]

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See detailUltrasonography and histology of equine menisci; a comparative study of the medial
De Busscher,V; Gabriel, Annick ULg; Cassart, Dominique ULg et al

Poster (2007, January)

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See detailDie Notfalltracheotomie beim Pferd
Carstanjen, B.; Gabriel, Annick ULg

in Praktische Tierarzt (Der) (2007)

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See detailMorphology of the stifle menisci in dogs: preliminary study
De Busscher, Virginie; Letesson, Julien; Busoni, Valeria ULg et al

in Slovenian Veterinary Research (2007), 44

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See detailEvaluation of serum osteocalcin and CTX-I in Ardenner horses with special reference to juvenile interphalangeal joint disease.
Pastoret, V.; Carstanjen, B.; Lejeune, Jean-Luc ULg et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (2007), 54(9), 458-63

The first aim of this study was to establish a profile of age-related normal serum concentrations of osteocalcin (OC) in Ardenner horses. For this first part, blood samples from 49 healthy Ardenner horses ... [more ▼]

The first aim of this study was to establish a profile of age-related normal serum concentrations of osteocalcin (OC) in Ardenner horses. For this first part, blood samples from 49 healthy Ardenner horses were collected. The second aim was to study two biochemical markers of bone metabolism, OC and a carboxy-terminal cross-linking telopeptide of type I collagen (CTX-I), in 30 young Ardenner horses during 1 year. Amongst them, 17 showed lesions of juvenile degenerative joint disease in the distal forelimbs. A specific radioimmunoassay for equine OC was used to measure the serum concentration of the marker. The serum concentration of CTX-I was measured using a commercially available human assay validated for use in the horse. The effect of age, sex, season and health status (with or without lesions) was assessed. Levels of OC fall between birth and the adult stage: this decrease being most marked between birth and 1 year of age. This age-related decrease of OC was confirmed in the 30 young Ardenner horses, but CTX-I levels remained constant in this group. The Levels of the two markers changed significantly with the season with higher concentrations during the winter. No significant difference was shown either between the two sexes or between the two health statuses. [less ▲]

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See detailComparative ultrasonographic and morphologic appearance of femorotibial menisci in horses: a preliminary study
De Busscher, V.; Busoni, Valeria ULg; Schreder, A. et al

in Canifelis Hippos Proceedings (2007)

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See detailDistribution of nerve fibres in bovine and human mucosal associated lymphoid tissues
Defaweux, Valérie ULg; Dorban, G.; Antoine, Nadine ULg et al

Poster (2006, October)

Prion cell tropism varies significantly among animal species, depending on both the agent strain and host-specific factors. For example, prions show high lymphotropism in scrapie infected sheep and vCJD ... [more ▼]

Prion cell tropism varies significantly among animal species, depending on both the agent strain and host-specific factors. For example, prions show high lymphotropism in scrapie infected sheep and vCJD, but little, if any, in sCJD or BSE. In particular, the BSE strain is associated with significant PrP-res accumulation in tonsils, spleen and appendix in humans, whereas it is largely confined to the nervous system in infected cattle. Therefore, at least in the case of BSE and vCJD, it appears that host properties can influence the accumulation of the infectious agent in lymphoid organs. Mature FDC play an important role in prion pathogenesis, since neuroinvasion following peripheral challenge is significantly impaired in their absence. The proximity between these FDC and sympathetic nerve endings is known to affect the speed of prion neuroinvasion. In this study, we analysed the mucosal innervation and the interface between nerve fibres and FDC in bovine and human tonsils and in ileal and jejunal bovine Peyer’s patches using a panel of antibodies observed by confocal microscopy. Since differences in the innervation of lymphoid organs depending on age have been reported, we analysed three categories of bovine ages (new born calves, calves less than 12 months old and bovines older than 24 months) and two categories of human ages (patients less than 5 years old and patients older than 25 years). In both species, hypothetical ways of innervation by-passing germinal centre could be postulated: nerve fibres are widely distributed in antigens/cells traffic area (the lamina propria, the interfollicular zone, the suprafollicular dome in Peyer’s patches and the lymphoepithelial area in tonsils). We pointed out that, only in ileal and jejunal Peyer’s patches and in tonsils of bovines older than 24 months, nerve fibres are observed to be in contact with FDC. In contrast, in human tonsils, no nerve fibres established contact with FDC, whatever the age. Thus, innervation of germinal centres can be said to be an age-dependent dynamic process in bovines and a weak innervation of the secondary lymphoid organs could thus be a rate-limiting step to neuroinvasion in humans. This variation could influence the way of neuroinvasion and thus, the differences of susceptibility of bovines and humans to the BSE agent. [less ▲]

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