References of "Focant, Jean-François"
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See detailFast Chromatographic Method for Explosive Profiling
Stefanuto, Pierre-Hugues ULg; Perrault, Katelynn A.; Focant, Jean-François ULg et al

in Chromatography (2015), 2

Security control is becoming a major global issue in strategic locations, such as airports, official buildings, and transit stations. The agencies responsible for public security need powerful and ... [more ▼]

Security control is becoming a major global issue in strategic locations, such as airports, official buildings, and transit stations. The agencies responsible for public security need powerful and sensitive tools to detect warfare agents and explosives. Volatile signature detection is one of the fastest and easiest ways to achieve this task. However, explosive chemicals have low volatility making their detection challenging. In this research, we developed and evaluated fast chromatographic methods to improve the characterization of volatile signatures from explosives samples. The headspace of explosives was sampled with solid phase micro-extraction fiber (SPME). Following this step, classical gas chromatography (GC) and comprehensive two-dimensional GC (GC×GC) were used for analysis. A fast GC approach allows the elution temperature of each analyte to be decreased, resulting in decreased thermal degradation of sensitive compounds (e.g., nitro explosives). Using fast GC×GC, the limit of detection is further decreased based on the cryo-focusing effect of the modulator. Sampling of explosives and chromatographic separation were optimized, and the methods then applied to commercial explosives samples. Implementation of fast GC methods will be valuable in the future for defense and security forensics applications. [less ▲]

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See detailGCxGC-TOFMS and supervised multivariate approaches to study human cadaveric decomposition olfactive signatures
Stefanuto, Pierre-Hugues ULg; Perrault, Katelynn A.; Stadler, Sonja et al

in Analytical Bioanalytical Chemistry (2015), 407(16), 4767-4778

In forensic thanato-chemistry, the understanding of the process of soft tissue decomposition is still limited. A better understanding of the decomposition process and the characterization of the ... [more ▼]

In forensic thanato-chemistry, the understanding of the process of soft tissue decomposition is still limited. A better understanding of the decomposition process and the characterization of the associated volatile organic compounds (VOC) can help to improve the training of victim recovery (VR) canines, which are used to search for trapped victims in natural disasters or to locate corpses during criminal investigations. The complexity of matrices and the dynamic nature of this process require the use of comprehensive analytical methods for investigation. Moreover, the variability of the environment and between individuals creates additional difficulties in terms of normalization. The resolution of the complex mixture of VOCs emitted by a decaying corpse can be improved using comprehensive two-dimensional gas chromatography (GC× GC), compared to classical singledimensional gas chromatography (1DGC). This study combines the analytical advantages of GC×GC coupled to timeof- flight mass spectrometry (TOFMS) with the data handling robustness of supervised multivariate statistics to investigate the VOC profile of human remains during early stages of decomposition. Various supervised multivariate approaches are compared to interpret the large data set. Moreover, early decomposition stages of pig carcasses (typically used as human surrogates in field studies) are also monitored to obtain a direct comparison of the two VOC profiles and estimate the robustness of this human decomposition analog model. In this research, we demonstrate that pig and human decomposition processes can be described by the same trends for the major compounds produced during the early stages of soft tissue decomposition. [less ▲]

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See detailINCREASE OF SENSITIVITY BY USING TIMED-CRYOGENIC ZONE COMPRESSION (t-CZC) APPLIED TO BDE-209 ON GC/HRMS
Mehlmann, H; Krumwiede, D; Focant, Jean-François ULg

Conference (2015, April)

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See detailHow far are we in the chase after the lowest detectable level for Dioxins?
Focant, Jean-François ULg; L'Homme, B; Calaprice, Chiara ULg et al

Scientific conference (2015, April)

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See detailGC×GC-TOFMS: A tool to demystify…
Focant, Jean-François ULg

Conference (2015, April)

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See detailMeasurement of ultra-trace levels of Dechloranes in food and feed. Assessment of dietary intake
Calaprice, Chiara ULg; L'Homme, Benjamin; Calvano, Cosima Damina et al

Conference (2015, April)

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See detailDioxins in food, Challenges in Analysis
Focant, Jean-François ULg

Scientific conference (2015, March 19)

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See detailDioxins in food, Challenges in Analysis
Focant, Jean-François ULg

Scientific conference (2015, March 17)

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See detailDioxin Strategies for the Triple Quadrupole Market
Focant, Jean-François ULg

Scientific conference (2015, March 16)

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See detailDioxins in food Challenges in Analysis
Focant, Jean-François ULg

Scientific conference (2015, March)

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See detailExploring new dimensions in cadaveric decomposition odour analysis
Stefanuto, Pierre-Hugues ULg; Perrault, Katelynn; Lloyd, Rebecca et al

in Analytical Methods (2015), 7

This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound ... [more ▼]

This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound analysis in the forensic sciences. High-resolution mass spectral data provided higher confidence in analyte identification. GC×GC-HRTOFMS will be valuable for future studies of decomposition odour and other complex volatile matrices. [less ▲]

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See detailLaboratoire de chimie analytique organique et biologique - Part 2
Focant, Jean-François ULg

in Bulletin ACLg (2015)

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See detailMeasurement of Human Internal Cadaveric VOC's by GCxGC-HRTOFMS
Stefanuto, Pierre-Hugues ULg; Varlet, Vincent; Silke et al

Conference (2015, January)

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See detailRecent Advances in the MS Measurement of Dioxins and other POPs
Focant, Jean-François ULg

Scientific conference (2015)

Detailed reference viewed: 14 (2 ULg)