References of "Focant, Jean-François"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailIn vitro monitoring of human tissue degradation by TD-GC×GC-TOFMS
Stefanuto, Pierre-Hugues ULg; Dubois, Lena ULg; DELPORTE, Géraldine ULg et al

Conference (2016, January 27)

Human rescue dog unit are amongst the most efficient tools to locate cadaver or individuals trapped after a natural disaster. However, the dog training process is long and expensive. Dog trainers are ... [more ▼]

Human rescue dog unit are amongst the most efficient tools to locate cadaver or individuals trapped after a natural disaster. However, the dog training process is long and expensive. Dog trainers are still looking for a better understanding of the dog olfaction matching mechanism to improve their training methods (1). How does the decomposition process differ between organs? Are there specific body parts better suited for dog training? What are the major volatile compounds responsible of the dogs’ match response? In the line of these questions, this project was monitoring the headspace of various human organs during the decomposition process. Five different organs, from five different bodies, were used: heart, lung, liver, kidney, and blood. Each organs were sampled in triplicates and let to decompose in glass jar. Regularly, the headspace of the jar was sampled by dynamic pumping to sorbent tubes that were further be desorbed on a comprehensive two-dimensional gas chromatography system (GC×GC). GC×GC is a powerful analytical tool that allows the resolution of “the smell of death”, i.e. the decomposition odor (2-3). The development of an in vitro approach for decomposition monitoring provided several analytical improvements in the decomposition field. Indeed, the study of dead bodies is always limited in the number of replicates (4). The sampling process developed for this project allows intra and inter corpse comparison with at least triplicates sampling. These comparisons were conducted using advanced chemometric methods (Fisher ratio, PCA, hierarchical analysis…) that will contribute to better understand key parameters of rescue the dog training. References 1. Hoffman et al. FSI (2009) 186, 6-13. 2. Stefanuto et al. CPC (2014) 79, 786-789. 3. Perrault et al. J. Sep. Sci. (2015) 38, 73-80. 4. Stefanuto et al. ABC (2015) 407, 4767-4778 [less ▲]

Detailed reference viewed: 49 (3 ULg)
Full Text
Peer Reviewed
See detailGC×GC-TOFMS, the Swiss Knife for VOC Mixtures Analysis in Soil Forensic Investigations
Stefanuto, Pierre-Hugues ULg; Focant, Jean-François ULg

in Soil in Criminal and Environmental Forensics (2016)

The study of the ‘smell of death’ is an important part of the thanatochemistry, the chemistry of death. Since 2004 (Vass et al. 2004), an increasing number of studies have been conducted to understand the ... [more ▼]

The study of the ‘smell of death’ is an important part of the thanatochemistry, the chemistry of death. Since 2004 (Vass et al. 2004), an increasing number of studies have been conducted to understand the body decomposition process by measuring the Volatile Organic Compounds (VOCs) released by decaying bodies. However, the chemical profi le of the decomposition odor is still far for from being resolved. Indeed, the complexity of the VOC mixture makes it diffi cult to be carried out by classical GC-MS. A better understanding of the decomposition process could thus possibly be achieved using a multidimensional technique such as Comprehensive Two Dimensional Gas Chromatography coupled to time of fl ight mass spectrometry (GC×GC-TOFMS). The high peak capacity of this multidimensional technique combined with the visualization power of multivariate statistical methods allows a deeper understanding of complex VOC matrices. [less ▲]

Detailed reference viewed: 10 (2 ULg)
Full Text
Peer Reviewed
See detailCryogenic zone compression GC-HRTOFMS for the measurement of PCB-153 and DDE in 20 mL serum samples
L'homme, Benjamin; Focant, Jean-François ULg

in Analytical Methods (2016), 8

Detailed reference viewed: 9 (0 ULg)
Full Text
See detailChasing the Dioxin Detection Dragon
Focant, Jean-François ULg

in The Analytical Scientist (2016), 0316-701

Detailed reference viewed: 12 (2 ULg)
Peer Reviewed
See detailgrteg
Focant, Jean-François ULg

Conference (2016)

Detailed reference viewed: 14 (2 ULg)
See detailFatty Matrices Cleaned-up with a Di erent Approach
Calaprice, Chiara ULg; Focant, Jean-François ULg

Scientific conference (2015, October)

Detailed reference viewed: 7 (1 ULg)