References of "Flandroy, P."
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See detailDegradation behaviour of poly(D,L)lactide microspheres for chemoembolization
Flandroy, P; Grandfils, Christian ULg; Daenen, B et al

Conference (1994, June 14)

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See detailQuand la chimie s’en mêle
Flandroy, P; Grandfils, Christian ULg

in le Journal du Médecin (1994), 16

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See detailNeuroblastome primitif du système nerveux central
Jamblin, Paul; Collignon, J.; Flandroy, P. et al

in Revue Neurologique (1993), 149

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See detailDesign of biodegradable microspheres for chemoembolization
Grandfils, Christian ULg; Flandroy, P; Jérôme, Robert ULg et al

Conference (1992, April 01)

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See detailPreparation of poly(D,L)lactide microspheres by emulsion-solvent evaporation and their clinical applications as a convenient embolic material
Grandfils, Christian ULg; Flandroy, P; Nihant, N et al

in Journal of Biomedical Materials Research (1992), 26

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See detailTreatment of macroprolactinomas with the long-acting and repeatable form of bromocriptine: a report on 29 cases.
Beckers, Albert ULg; Petrossians, Patrick ULg; Abs, R. et al

in Journal of Clinical Endocrinology and Metabolism (1992), 75(1), 275-80

Twenty-nine patients with macroprolactinomas were treated by monthly intramuscular injections of the long-acting and repeatable form of bromocriptine (Parlodel-LAR) in doses ranging from 50-150 mg. They ... [more ▼]

Twenty-nine patients with macroprolactinomas were treated by monthly intramuscular injections of the long-acting and repeatable form of bromocriptine (Parlodel-LAR) in doses ranging from 50-150 mg. They were divided into two groups: group I consisted of 22 patients who received Parlodel LAR before transsphenoidal adenomectomy; group II was composed of 7 patients with earlier neurosurgery and of 2 patients from group I not cured by transsphenoidal adenomectomy. Duration of therapy varied from 1-12 months, and a total of 104 injections was given. At nadir day, serum PRL levels were situated between less than 1% and 43% of pretreatment values. At day 28 after the first injection, serum PRL levels varied between less than 1% to 139% of initial values. No difference could be detected between the two groups regarding the percent of PRL inhibition. Long-term treatment with Parlodel-LAR resulted in a sustained inhibition of PRL secretion, except for 1 case. Resumption of menstrual cycles occurred in 4 out of 15 women and correction of hypogonadism in 4 out of 14 men. Amelioration of disturbed visual fields was recorded in 3 out of 8 patients. Diminution of the adenoma volume was radiologically documented in 14 out of 22 cases. Only few and mild side effects were recorded. One patient with partial adrenal deficiency suffered from a syncope, but this was prevented by hydrocortisone supplementation during the subsequent Parlodel-LAR administration. In conclusion, Parlodel-LAR proved effective in the treatment of macroprolactinomas, achieving rapid inhibition of PRL secretion, and in some patients amelioration of hypopituitarism, reduction in tumor size, and improvement in visual fields, and caused no serious side effects. It is a valuable preparation to surgery and can also be used in long-term medical therapy. [less ▲]

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See detailSynthetic biomedical polymers
Grandfils, Christian ULg; Dubois, Philippe ULg; Barakat, I et al

Poster (1991, November 28)

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See detailMR of radiation induced myelopathy.
Collignon, F.; Flandroy, P.; Martin, Didier ULg et al

Conference (1991, October 06)

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See detailPreparation of poly(D,L)lactide microspheres and their clinical applications as a convenient embolic material
Grandfils, Christian ULg; Flandroy, P; Nihant, N et al

Conference (1990, September)

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See detailEmpty (D,L) Polylactide microspheres as Embolic Material. A preliminary step to chemoembolization.
Flandroy, P; Grandfils, Christian ULg; Collignon, J et al

Conference (1990, June 17)

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See detailLes microsphères d'acide polylactique comme matériels d'embolisation
Flandroy, P; Grandfils, Christian ULg

Conference (1990, May 28)

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See detailExperimental acute spinal cord injury using subdural inflatable balloon
Martin, Didier ULg; Delrée, P.; Schoenen, J. et al

Conference (1990, May)

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See detailNouveaux matériaux destinés à l'embolisation : les microsphères d'acide polylactique
Flandroy, P; Grandfils, Christian ULg

Conference (1990, March 06)

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See detailCyclical Cushing's disease and its successful control under sodium valproate.
Beckers, Albert ULg; Stevenaert, Achille ULg; Pirens, G. et al

in Journal of Endocrinological Investigation (1990), 13(11), 923-9

Several subgroups of Cushing's disease were recently described (anterior or intermediate lobe origin, hyper-or hypo-pulsatility of cortisol, presence or absence of response after GRH or TRH, cyclical ... [more ▼]

Several subgroups of Cushing's disease were recently described (anterior or intermediate lobe origin, hyper-or hypo-pulsatility of cortisol, presence or absence of response after GRH or TRH, cyclical Cushing's disease). We present here a detailed case report on a patient suffering from Cushing's disease whose endocrine functions were extensively investigated. Treatment with bromocriptine, as well as subsequent transsphenoidal surgery, were followed by rapid but transient reversal of symptoms. When clinical manifestations reoccurred, daily measurements of free urinary cortisol revealed a cyclic pattern of cortisol hyperexcretion. A study of ultradian rhythm revealed hyperpulsatility of cortisol secretion. More interestingly, a treatment with sodium valproate, a drug known to inhibit CRH production, was followed by a rapid and longstanding normalization of clinical and biological data for 2 years. Based on these data, and on information from the literature, the present case of Cushing's disease exhibits characteristics suggesting a possible hypothalamic origin. [less ▲]

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See detailLes hernies discales intradurales
Martin, Didier ULg; Mouchamps, M.; Collignon, Jacques ULg et al

Conference (1987, March 14)

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