References of "Farnir, Frédéric"
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See detailTwo-Dimensional, M-Mode and Pulsed Wave Doppler Echocardiographic Reference Values in Healthy Adult Saanen Goats
Leroux, Aurélia ULg; Moonen, Marie ULg; Farnir, Frédéric ULg et al

Poster (2011, March 18)

Echocardiography has become a routine non invasive cardiac diagnostic tool in most species. Accurate measurement of cardiac dimensions requires reference values, which are poorly documented in goats ... [more ▼]

Echocardiography has become a routine non invasive cardiac diagnostic tool in most species. Accurate measurement of cardiac dimensions requires reference values, which are poorly documented in goats. Goats are animals easy to handle with a body and heart size comparable to humans’. This makes goats an attractive candidate for the development of animal models for human cardiology research. The aim of this study was to test the repeatability and to establish the reference values of bi-dimensional (2D-), time-motion (M-) mode and pulsed wave (PW) Doppler echocardiographic variables in adult goats. Six healthy female adult Saanen goats were investigated three times by the same observer at one day interval using a standardized 2D-, M-mode and PW Doppler echocardiographic protocol. Calculation of the coefficient of variation for each variable measured within day and depending on the day allowed to evaluate their degree of variability. A single echocardiographic examination was performed in 6 other goats by the same observer, and the obtained values were added to these obtained on the third day of the 6 first goats. Then the observed mean, the standard deviation and the range of these measurements were calculated to establish the reference values of echocardiographic parameters in unsedated adult healthy female Saanen goats. Statistical analysis revealed a good inter-day repeatability of the 2D- and M-mode echocardiographic cardiac measurements, but PW Doppler parameters presented moderate to high variability, as documented in other species. Echocardiographic reference values obtained in healthy adult Saanen goats were similar to those reported in healthy adult sheep and in healthy adult humans. [less ▲]

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See detailContrôle de l'involution utérine au moyen de l'écographie transabdominale en mode B : validation de la technique
Thilmant; Paniagua, S; Farnir, Frédéric ULg et al

in Colloques de la 43e Journée de la Recherche Porcine (2011, February 15)

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See detailDuration of corneal anaesthesia following multiple doses and two concentrations of tetracaine hydrochloride eyedrops on the normal equine cornea
Monclin, Sébastien ULg; Farnir, Frédéric ULg; Grauwels, Magda ULg

in Equine Veterinary Journal (2011), 43(1), 69-73

REASONS FOR PERFORMING STUDY: There is a clinical impression that tetracaine hydrochloride (THCl) eyedrops is a suitable topical anaesthetic in horses. OBJECTIVE: To determine the duration of corneal ... [more ▼]

REASONS FOR PERFORMING STUDY: There is a clinical impression that tetracaine hydrochloride (THCl) eyedrops is a suitable topical anaesthetic in horses. OBJECTIVE: To determine the duration of corneal anaesthesia following instillation of multiple doses and 2 concentrations of THCl in 10 healthy horses. METHODS: The corneal touch threshold (CTT) was determined, in both eyes, before (basal CTT) and after application of one drop of 0.5% THCl, 2 drops at a 1 min interval of 0.5% THCl or one drop of 1% THCl. CTT was measured in mm every 5 min until complete recovery of the basal CTT. Treatments were separated by an interval of at least one week. RESULTS: Corneal sensitivity was significantly reduced from baseline values for 30, 60 and 50 min after application of one drop of 0.5% THCl, 2 drops of 0.5% THCl and one drop of 1% THCl, respectively. Mean maximal anaesthetic effects, corresponding to a CTT of 0 mm, lasted 5.5, 16 and 15.25 min and maximal anaesthetic effect was present in 55, 90 and 80% of eyes, 5 min after application of one drop of 0.5% THCl, 2 drops of 0.5% THCl and one drop of 1% THCl, respectively. CONCLUSIONS: The application of a second drop or the use of more concentrated eyedrops significantly increases duration of both anaesthesia and maximal anaesthetic effect. POTENTIAL RELEVANCE: Duration of corneal anaesthesia following tetracaine instillation was established enabling a better use when performing diagnostic and therapeutic procedures. Comparison of tetracaine with other ocular anaesthetics needs to be published in the future. [less ▲]

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See detailDetermination of Tear Break-up Time reference values and ocular tolerance of tetracaine hydrochloride eyedops in healthy horses
Monclin, Sébastien ULg; Farnir, Frédéric ULg; Grauwels, Magda ULg

in Equine Veterinary Journal (2011), 43(1), 74-77

REASONS FOR PERFORMING STUDY: Tetracaine hydrochloride (THCl) has been reported to cause irritation in dogs. In man, some topical anaesthetics have been shown to disrupt the tear film. Tear break-up time ... [more ▼]

REASONS FOR PERFORMING STUDY: Tetracaine hydrochloride (THCl) has been reported to cause irritation in dogs. In man, some topical anaesthetics have been shown to disrupt the tear film. Tear break-up time (TBUT) is a useful test allowing an assessment of the quality of the precorneal tear film. Only one TBUT value has been reported in horses with no information on the technique used. OBJECTIVES: To provide a method for performing the TBUT in horses and to report any side effects of a single application of THCl in clinically normal horses, particularly on the stability of the tear film. METHODS: In Study 1, one drop of 0.5 or 1% THCl was applied to one eye of 20 horses divided in 2 groups. Treated eyes were assessed for the development of side effects 2.5 and 5 min after treatment. In Study 2, the TBUT was measured in both eyes of 2 groups of 10 horses, before and 2.5 and 5 min after, instillation of one drop of either 0.5 or 1% THCl. RESULTS: No animals developed any ocular side effect after instillation. Basal TBUT was 8.3±1.3 s. TBUT decreased from baseline 5 and 2.5 min after application of one drop of 0.5% THCl and one drop of 1% THCl, respectively. CONCLUSIONS: A technique to measure the TBUT in healthy horses is described and normal range values that could be used as a reference were obtained. POTENTIAL RELEVANCE: THCl is well tolerated in horses but lowers the TBUT. [less ▲]

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See detailMuscular forces affecting the outcome of CCL surgery
Ramirez, J.; Böhme, Béatrice ULg; Vroomen, Carl ULg et al

in Proceedings of the 20th ECVS Congress (2011)

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See detailMuscular forces affecting the outcome of CCL surgery.
Ramirez, L.; Böhme, Béatrice ULg; Vroomen, Carl ULg et al

in Proceedings of the 20th ECVS Congress (2011)

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See detailThe Ri chicken breed and livelihoods in North Vietnam: characterisation and prospects
Moula, Nassim ULg; Do Duc, Luc ULg; Pham Kim, Dang et al

in Journal of Agriculture and Rural Development in the Tropics and Subtropics (2011), 112(1), 57-69

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See detailSkin mucus of Cyprinus carpio inhibits cyprinid herpesvirus 3 binding to epidermal cells
RAJ, Victor; Fournier, Guillaume ULg; Rakus, Krzysztof ULg et al

in Veterinary Research (2011), 42(92),

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See detailVariants modulating the expression of a chromosome domain encompassing PLAG1 influence bovine stature.
Karim, Latifa ULg; Takeda, Haruko ULg; Lin, Li et al

in Nature Genetics (2011), 43(5), 405-13

We report mapping of a quantitative trait locus (QTL) with a major effect on bovine stature to a approximately 780-kb interval using a Hidden Markov Model-based approach that simultaneously exploits ... [more ▼]

We report mapping of a quantitative trait locus (QTL) with a major effect on bovine stature to a approximately 780-kb interval using a Hidden Markov Model-based approach that simultaneously exploits linkage and linkage disequilibrium. We re-sequenced the interval in six sires with known QTL genotype and identified 13 clustered candidate quantitative trait nucleotides (QTNs) out of >9,572 discovered variants. We eliminated five candidate QTNs by studying the phenotypic effect of a recombinant haplotype identified in a breed diversity panel. We show that the QTL influences fetal expression of seven of the nine genes mapping to the approximately 780-kb interval. We further show that two of the eight candidate QTNs, mapping to the PLAG1-CHCHD7 intergenic region, influence bidirectional promoter strength and affect binding of nuclear factors. By performing expression QTL analyses, we identified a splice site variant in CHCHD7 and exploited this naturally occurring null allele to exclude CHCHD7 as single causative gene. [less ▲]

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See detailẢnh hưởng của allen halothane đến khả năng sinh trưởng của lợn và sự xuất hiện tần số kiểu gen ở đời sau
Do Duc, Luc ULg; Thanh, Nguyen Chi; Dinh, Bui Van et al

in Journal of Science and Development (2011), 9(2), 225-232

A total of 395 tail samples of stress negative Piétrain new born piglets from the pig farm of Dong Hiep Haiphong were used to determine halothane genotypes (CC, CT and TT) in order to study the effect of ... [more ▼]

A total of 395 tail samples of stress negative Piétrain new born piglets from the pig farm of Dong Hiep Haiphong were used to determine halothane genotypes (CC, CT and TT) in order to study the effect of mating type (♂CC×♀CC, ♂CC×♀CT, ♂CT×♀CC, and ♂CT×♀CT) on halothane genotype frequencies. Effects of genotype on live weight (174 pigs of 2 month old, 96 pigs of 5.5 month old), back fat thickness, loin muscle thickness and lean percentage (117 pigs), average daily gain (89 pigs) were also studied. Results showed that the mating type affected halothane genotype frequencies in the progeny. For the mating type ♂CC×♀CT and ♂CT×♀CT, the genotype containing allele T was reduced in the next generation; in the rest two genotypes (♂CC×♀CC and ♂CT×♀CC) the halothane allele frequency in the offspring was consistent with the theoretical frequency. The halothane genotypes CC and CT did not affect live weights at 2.0 and 5.5 months of age, average daily gain, backfat thickness, loin muscle thickness and lean percentage. [less ▲]

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See detailCytochrome P450 1A1 expression in cetacean skin biopsies from the Indian Ocean
Jauniaux, Thierry ULg; Farnir, Frédéric ULg; Fontaine, Michael et al

in Marine Pollution Bulletin (2011)

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See detailPigeon circovirus: baculovirus expression of the capsid protein gene, specific antibody and viral load measured by real time polymerase chain reaction
Duchatel, Jean-Pierre ULg; Todd, D.; Smyth, J. et al

in Israel Journal of Veterinary Medicine (2011), 66(1), 26-31

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See detailChỉ tiêu huyết học của lợn Piétrain kháng stress nuôi tại Xí nghiệp Chăn nuôi Đồng Hiệp Hải Phòng
Thach, Pham Ngoc; Do Duc, Luc ULg; Farnir, Frédéric ULg et al

in Journal of Science and Development (2010), 8(6), 969-974

This study was carried out on 50 stress negative Piétrain pigs (Pietrain ReHal): 15 pigs at 2 months of age, 20 pig at 5.5 months of age, 5 boars and 10 sows raised in the livestock farm of Dong Hiep, Hai ... [more ▼]

This study was carried out on 50 stress negative Piétrain pigs (Pietrain ReHal): 15 pigs at 2 months of age, 20 pig at 5.5 months of age, 5 boars and 10 sows raised in the livestock farm of Dong Hiep, Hai Phong in order to establish the hematological reference values and their variability according to 4 groups of pigs (2 months, 5.5 months old, boar and sow). Significant group differences were found in hematological parameters except red cells, hemoglobin, eosinophil, basophil, total protein and sugar. These values were within the normal ranges generally accepted as reference values for healthy pigs. Piétrain stress negatif pigs could gradually adapt to the animal production condition in Hai Phong, Vietnam. [less ▲]

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See detailAltered systolic left ventricular function in horses completing a long distance endurance race
Amory, Hélène ULg; Votion, Dominique ULg; Fraipont, A. et al

in Equine Veterinary Journal. Supplement (2010), 42(38), 216-219

Reasons for performing the study: It is unknown whether exercise-induced cardiac fatigue (EICF), as demonstrated in athletes performing long duration exercise, occurs in endurance horses. Objective: To ... [more ▼]

Reasons for performing the study: It is unknown whether exercise-induced cardiac fatigue (EICF), as demonstrated in athletes performing long duration exercise, occurs in endurance horses. Objective: To examine the effects of a long distance endurance race on left ventricular systolic function in horses. Methods: Echocardiography was performed before and after a 2 or 3 star international endurance race (106 to 132 km) in 11 horses. Systolic (s) and diastolic (d) interventricular and left ventricular free wall thickness (IVS and LVFW, respectively), left ventricular, left atrial and aortic internal diameter (LVID, LA and Ao, respectively), fractional shortening (FS) and ejection fraction (EF) were measured by echocardiography. Heart rate (HR), peak flow velocity (Vmax), flow velocity integral (FVI), ejection time (ET), pre-ejection period (PEP), velocity of circumferential fiber shortening (Vcf), stroke volume (SV) and cardiac output (CO) were measured from aortic Doppler wave recordings. Results: After the race, LVIDd, Ao, LA, EF, FS, FVI, SV, ET and ET indexed for HR were significantly lower and IVSd, LVFWd, HR, PEP, PEP/ET, and Vcf were significantly higher as compared with pre-race values. Pre- to post-exercise changes in those parameters were not significantly correlated with changes in HR or in LVIDd. Conclusions: Results suggest that EICF, with a decrease in left ventricular systolic function, could occur post-exercise in horses performing long duration endurance races. However, a confounding effect of altered preload and heart rate on the studied variables cannot be discounted. [less ▲]

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See detailGenetic analysis of a glomerulonephropathy segregating in a pedigree of French Mastiff.
Battaille, Géraldine ULg; Lavoué, Rachel ULg; Peeters, Dominique ULg et al

in Proceedings of 32nd Annual Conference of the International Society of Animal Genetics (2010)

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See detailComparison of the Repeatability of Echocardiographic Measurements from Different Modes and Views in Horses of Various Breeds and Sizes
Al Haidar, Ali; Farnir, Frédéric ULg; Deleuze, Stefan ULg et al

in Journal of Equine Veterinary Science (2010), 30(6), 287-297

The objective of this study was to compare the repeatability of echocardiographic measurements obtained from different echocardiographic modes and views in healthy adult equids of various sizes, breeds ... [more ▼]

The objective of this study was to compare the repeatability of echocardiographic measurements obtained from different echocardiographic modes and views in healthy adult equids of various sizes, breeds and thorax shapes. Ten, free of cardiac disease, equids (body weight: 120 to 662 kg; age: 1 to 26 years) from various breeds were used in this study. Each animal was submitted to a standardized echocardiographic and Doppler protocol 3 times at 1 day interval. This protocol included the measurements of left and right ventricular, aortic, pulmonary, and left atrial parameters obtained from different views using the bidimensional (2D) or the motion (M) modes, and the measurement of several parameters of blood flow obtained from the pulsed wave Doppler mode. Repeatability of each measurement was estimated on the basis of the residual variance using a linear model and the coefficient of variation of repeated measurements. A two by two comparison of the repeatability of measurements performed in different views was performed using the residual variances in a variance ratio F test. Results showed that repeatability of echocardiographic or Doppler measurements in equids of various sizes, breeds and thorax shapes are comparable to previously reported results in thoroughbred and standardbred horses. Left ventricular morphologic parameters showed a good repeatability in the classic M-mode right parasternal short axis (Sax) view at the level of the chordae tendinae, but the 2D-mode right parasternal long axis (LAx) four- chambers view appeared to offer an interesting alternative to measure them. This latter view also allowed obtaining the mostre repeatable measurement of right ventricular internal diameter. The left atrial diameter was maximal and most repeatable in the 2D-mode left parasternal long axisLAx four- chambers angled view, and the repeatability of the aortic diameter was best in the 2D-mode right parasternal long axisLAx five-chambers view. Finally, aortic systolic time intervals were more repeatable when measured from the Doppler mode as compared to the M-mode. ThusIn conclusion, best repeatability of echocardiographic measurements in horses could be optimized following an echocardiographicthe following protocol in equids: 1-M-mode right parasternal short axis view at the level of chordae tendinae, to measure left ventricular morphologic parameters, and 2D-mode right parasternal long axis four-chamber as an alternative view. 2-2D-mode right parasternal long axis five-chambersre, to measure the aortic diameter. 3-2D-mode left parasternal long axis four-chambersre angled view, to measure the left atrial diameter. [less ▲]

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See detailComparative study of egg quality traits in two Belgian local breeds and two commercial lines of chickens
Moula, Nassim ULg; Antoine-Moussiaux, Nicolas ULg; Decuypere, Eddy et al

in Archiv Für Geglügelkunde = European Poultry Science = Revue de Science Avicole Européenne (2010), 74(3), 164-171

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See detailAltered diastolic and systolic left ventricular function in horses completing a long distance endurance race
Amory, Hélène ULg; Votion, Dominique ULg; Fraipont, Audrey ULg et al

in In Proceedings of the 8th International Conference on Equine Exercise Physiology (ICEEP) (2010)

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