References of "FRANCHIMONT, Claudine"
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See detailPeelings chimiques et vieillissement cutané.
Uhoda, Emmanuelle ULg; Bourguignon, Raphaël; Thirion, Laurence et al

in Skin (2005), 8

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See detailLes antibiotiques topiques en Europe: résistances insulaires et indifférence continentale?
Henry, Frédérique ULg; Thirion, Laurence; Franchimont, Claudine ULg et al

in Dermatologie Actualité (2005), 92

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See detailLe vieillissement cutané dans tous ses états.
Thirion, Laurence; Uhoda, Emmanuelle ULg; Henry, Frédérique ULg et al

in Pharma-Sphère (2005), 101

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See detailLes onychomycoses au-delà de la bagatelle, des fadaises et des "carabistouilles".
Pierard, Gérald ULg; Bourguignon; Arrese Estrada, Jorge ULg et al

in Dermatologie Actualité (2005), 91

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See detailPityriasis versicolor anhidrotique.
Uhoda, Emmanuelle ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Dermatologie Actualité (2005), 89

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See detailCheveux et risques environnementaux.
Franchimont, Claudine ULg; Pierard, Gérald ULg

in Skin (2005), 8

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See detailLe lymphome T anaplasique CD30 positif cutané primitif, une affection au pronostic favorable.
Flagothier, Caroline ULg; Quatresooz, Pascale ULg; Franchimont, Claudine ULg et al

in Dermatologie Actualité (2004), 80

Le mycosis fongoïde représente le plus fréquent des lymphomes primitifs de la peau. Le syndrome de Sézary et les lymphomes T anaplasiques sont beaucoup plus rares. Malgré un aspect cytologique très ... [more ▼]

Le mycosis fongoïde représente le plus fréquent des lymphomes primitifs de la peau. Le syndrome de Sézary et les lymphomes T anaplasiques sont beaucoup plus rares. Malgré un aspect cytologique très atypique, le lymphome T anaplasique CD30 positif à localisation cutanée primitive est un lymphome de pronostic favorable. Une concertation et une prise en charge multidisciplinaire sont nécessaires afin d’éviter les écueils d’une thérapeutique résolument trop agressive. [less ▲]

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See detailDe l'hypertension veineuse ambulatoire aux jambes lourdes et à la micro-angiopathie de stase.
Quatresooz, Pascale ULg; Franchimont, Claudine ULg; Henry, Frédérique ULg et al

in Gunaïkeia (2004), 9

L'insuffisance veineuse des membres inférieurs est un état physiopathologique insidieusement progressif qui se manifeste fréquemment chez la femme. Par la cascade de ses conséquences, elle entraîne une ... [more ▼]

L'insuffisance veineuse des membres inférieurs est un état physiopathologique insidieusement progressif qui se manifeste fréquemment chez la femme. Par la cascade de ses conséquences, elle entraîne une microangiopathie cutanée. L'ulcère chronique de jambe en est l'issue tardive avec son cortège d'aspects médicaux et socio-économiques. La pathogénie des lésions cutanées est en relation directe avec l'hémorrhéologie et l’adhésion des leucocytes intracapillaires. La migration de leucocytes dans les tissus périveinulaires, avec subséquemment une activation inappropriée de ces cellules, est en relation avec l’importance des troubles trophiques, de la lipodermatosclérose et de la chronicité des ulcères veineux. La contention élastique et quelques médications veinotropes exercent une action thérapeutique sur les symptômes de jambe lourde. Elles ont aussi des effets préventifs sur le développement du tableau progressif de cette pathologie microvasculaire. [less ▲]

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See detailDes jambes lourdes à la grosse jambe rouge.
Quatresooz, Pascale ULg; Franchimont, Claudine ULg; Henry, Frédérique ULg et al

in Vaisseaux, Coeur, Poumons [=VCP] (2004), 9

Venous insufficiency of the legs is a frequent and insidious disorder which, through its consequences’ cascade, lead to some cutaneous microangiopathy with relative ischemia. Chronic leg ulcer is the late ... [more ▼]

Venous insufficiency of the legs is a frequent and insidious disorder which, through its consequences’ cascade, lead to some cutaneous microangiopathy with relative ischemia. Chronic leg ulcer is the late issue of the process accompanied by varied medical and socio-economic aspects. The pathogeny of the cutaneous lesions is directly related to alterations in hemorrheology and leukocyte adhesion inside capillaries. Elastic contention and some venotropic drugs exert preventive effects on the development of leg ulcers. They also bring some therapeutic improvement of the symptoms of leg heaviness. [less ▲]

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See detailLa route métastatique du mélanome.
Quatresooz, Pascale ULg; Claessens, Nadine; Arrese Estrada, Jorge ULg et al

in Skin (2004), 7

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See detailRepair kinetics of stratum corneum under repeated insults.
Uhoda, Emmanuelle ULg; Franchimont, Claudine ULg; Debatisse, B. et al

in Exogenous Dermatology : Physical, Chemical, Biological (2004), 3

Background. The stratum corneum (SC) structure and functions are altered by surfactants. Enhancing the repair mechanisms is a goal for some skin care formulations. Aim. To design an experimental procedure ... [more ▼]

Background. The stratum corneum (SC) structure and functions are altered by surfactants. Enhancing the repair mechanisms is a goal for some skin care formulations. Aim. To design an experimental procedure allowing the discrimination of repair efficacy for topical products applied to threatened SC. Method. Controlled SC strippings followed by repeated forearm soak sessions in surfactant solutions were used to compromise the SC barrier function in 20 volunteers. Two test formulations were compared. They were applied twice daily for 2 weeks before initiating the SC damages, and for the next 2 weeks while sustaining the procedure of soak sessions. Daily assessments involved objective measurements of parameters including TEWL, the value of the passive sustainable SC hydration and the epidermal turnover rate using the dihydroxyacetone (DHA) test. Result. The experimental procedure allowed to clearly distinguish the differences in the kinetics of SC repair between the topical formulations. In the present study design, the repair of the barrier function mirrored the SC renewal. Conclusion. The present experimental design slows down the repair rate of the SC barrier function. Thus, it increases the sensitivity of biometrological measurements assessing some of the major SC properties. It also better mimicks the common in vivo situation experienced by subjects chronically exposed to irritant xenobiotics. [less ▲]

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See detailBiocénose cutanée, peptides antimicrobiens cutanés et antiseptiques.
Flagothier, Caroline ULg; Uhoda, Emmanuelle ULg; Goffin, Véronique ULg et al

in Dermatologie Actualité (2004), 86

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See detailItracoanzole in human aspergillosis revisited.
Pierard, Gérald ULg; Kharfi, M.; Salomon-Neira, M. D. et al

in Journal de Mycologie Médicale (2004), 14

Itraconazole is a broad spectrum antifungal agent of the bis-triazole class. The drug is an important option in the management of many human mycoses including various clinical presentations of ... [more ▼]

Itraconazole is a broad spectrum antifungal agent of the bis-triazole class. The drug is an important option in the management of many human mycoses including various clinical presentations of aspergillosis. Indeed, the compound exhibits potent in vitro antifungal activity against Aspergillus spp. and shows variable fungicidal effect against the different species and strains. After amphotericin B, itraconazole has been the very first agent, and the first azole antifungal to have demonstrated clinical efficacy in aspergillosis. In vivo, the antifungal efficacy of itraconazole has been demonstrated in several types of aspergillosis both in immunocompetent and immunocompromised animal models. The drug administered in its oral or intravenous formulations displays non-linear plasma pharmacokinetics. Despite best current therapies, the outcome of invasive aspergillosis may remain dismal. Fungal cells can induce enormous damage on a background of immunosuppression. Medical help comes often too slow or is too weak. It will be a long time before the ideal strategy is found for an effective prophylaxis or for the optimal therapy of disseminated and invasive aspergillosis. In spite of this limitation, itraconazole has a definite chemotherapeutic effect in experimental aspergillosis. Non-comparative clinical data of itraconazole in the treatment of suspected or proven invasive aspergillosis indicate response rates at least similar and possibly superior to those of amphotericin B. Itraconazole has clearly improved the clinical outcome in some of the less immunosuppressed patients with invasive aspergillosis. The experience with itraconazole for induction therapy of invasive aspergillosis is more limited in profoundly neutropenic patients. Itraconazole has an important role for consolidation and maintenance therapy of patients with invasive aspegillosis. Itraconazole oral cyclodextrin solution is particularly suitable in these indications. Novel combination and sequential therapies involving itraconazole with other antifungals are promising. Itraconazole is usually well tolerated, but a potential for drug interactions exists, mediated through the cytochrome P450 3A4 system. This possibility should be considered when itraconazole is used as part of a multi-drug regimen. [less ▲]

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See detailL'horloge chronobiologique de la peau.
Flagothier, Caroline ULg; Henry, Frédérique ULg; Franchimont, Claudine ULg et al

in Dermatologie Actualité (2004), 80

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