References of "Evrard, Brigitte"
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See detailDRUG DELIVERY NANOCARRIERS TO CROSS OF THE BLOOD-BRAIN BARRIER
Palazzo, Claudio ULiege; Karim, Reatul ULiege; Evrard, Brigitte ULiege et al

in Grumezescu, Alex (Ed.) Nanobiomaterials in drug delivery (2016)

Blood-brain barrier (BBB) is a brain protective structure composed by endothelial cells, astrocytes and pericytes characterized by specific transport systems expressed on their surface. Moreover, the ... [more ▼]

Blood-brain barrier (BBB) is a brain protective structure composed by endothelial cells, astrocytes and pericytes characterized by specific transport systems expressed on their surface. Moreover, the tight junctions, in the paracellular space, and the adherens junctions, in the basolateral space of the endothelial cells create a physical barrier hardly crossable from the most part of common drugs. Despite the BBB is vital for the central nervous system (CNS), it restricts drug delivery to this tissue. To overcome this obstacle many drug delivery systems (DDS) have been developed. Polymeric nanocarriers, solid lipid nanocarriers (SLN) and liposomes are developed to deliver drugs otherwise not able to pass the BBB, due to their physico-chemical characteristics. Besides their capacity to pass biological barriers, the potential advantages of nanocarriers are their capability to load a high quantity of drug with low cytotoxicity. [less ▲]

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See detailInvestigation of a suitable in vitro dissolution test for itraconazole-based solid dispersions
Thiry, Justine ULiege; Broze, Guy ULiege; Pestieau, Aude ULiege et al

in European Journal of Pharmaceutical Sciences (2016)

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See detailSelection of a discriminant and biorelevant in vitro dissolution test for the development of fenofibrate self-emulsifying lipid-based formulations
Pestieau, Aude ULiege; Krier, Fabrice; Brouwers, Adeline et al

in European Journal of Pharmaceutical Sciences (2016)

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See detailPegylated Polyplexes Based On HDAC5 siRNA And Aliphatic Polycarbonate Polymers For An Anticancer Therapy
Frère, Antoine ULiege; Baroni, Alexandra; Peulen, Olivier ULiege et al

Poster (2015, December)

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See detailPegylated Polyplexes Based On HDAC5 siRNA And Aliphatic Polycarbonate Polymers For An Anticancer Therapy
Frère, Antoine ULiege; Baroni, Alexandra; Peulen, Olivier ULiege et al

Poster (2015, November 23)

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See detailIn vitro and in vivo evaluation of an optimized fenofibrate lipid based solid dispersion produced by a PGSS process
Pestieau, Aude ULiege; Lebrun, Sonia; Cahay, Bernard et al

Conference (2015, October 28)

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See detailIn vitro and in vivo evaluation of an optimized fenofibrate lipid based solid dispersion produced by a PGSS process
Pestieau, Aude ULiege; Lebrun, Sonia; Cahay, Bernard et al

Poster (2015, October 28)

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See detailPolyplex Based on Polycarbonate Polymers for an Efficient Delivery of HDAC5 and HDAC7 siRNA
Frère, Antoine ULiege; Tempelaar, Sarah; Peulen, Olivier ULiege et al

Poster (2015, June 02)

Detailed reference viewed: 21 (5 ULiège)