References of "Ethgen, Olivier"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailTime-dependent risk of gastrointestinal complications induced by NSAIDS use: a consensus statement using meta-analytic approach
Richy, Florent; Bruyère, Olivier ULg; Ethgen, Olivier ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 9

Detailed reference viewed: 16 (3 ULg)
Peer Reviewed
See detailDo utility values and willingness to pay suitably reflect health outcome in hip and knee osteoarthritis? A comparative analysis with the WOMAC index
Ethgen, Olivier ULg; Tancredi, Annalisa ULg; Lejeune, Emmanuelle ULg et al

in Journal of Rheumatology (2003), 30(11), 2452-2459

Objective. To establish whether health utility (time trade-off, TTO) and willingness to pay (WTP) values reflect clinical health outcome as evaluated by the Western Ontario McMaster Universities ... [more ▼]

Objective. To establish whether health utility (time trade-off, TTO) and willingness to pay (WTP) values reflect clinical health outcome as evaluated by the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) in hip and knee osteoarthritis (OA). Methods. One hundred twenty-eight patients with OA attending a specialized arthritis clinic were interviewed about their socioeconomic characteristics and administered the TTO technique and the WOMAC. Their WTP for 2 hypothetical anti-osteoarthritic drugs was also investigated: the first drug was said to provide a significant improvement in WOMAC dimensions and the second a complete cure of the disease. WTP was elicited by both discrete-choice and bidding game methods. Results. Answer rates were 89.1% for TTO, 98.4% for discrete-choice WTP for both scenarios, and 89.8% and 85.2% for bidding game WTP in the relief and the cure scenario, respectively. The mean TTO utility value was 0.84 (standard deviation 0.20). In discrete-choice, those accepting the bid had higher monthly income (euro 1536.5 vs euro 1060. 1, p < 0.001, for the relief scenario and euro 1449.3 vs euro 1071.6, p < 0.001, for the cure scenario). With the bidding game format, WTP was positively correlated with income in both scenarios (r = 0.56, r = 0.55, p < 0.001). WTP measures differed equally between education and socioeconomic groups with those in favored groups consistently reporting higher WTP (Kruskal-Wallis tests statistics ranging from p < 0.01 to p < 0.001). Except for stiffness, WOMAC dimensions were correlated in the expected direction with TTO values (r = -0.27, p < 0.01 for pain and r = -0.36, r = -0.34, p < 0.001 for physical function and total score, respectively). Conclusion. Whereas they showed good feasibility, WTP measures poorly reflected clinical condition and were mainly related to economic status and ability to pay. TTO was correlated with the WOMAC dimensions and may be considered closer to clinical situations than WTP. However, concern arises regarding the homogeneity of the study sample in terms of clinical severity, which may have precluded the identification of a relationship between WTP and clinical status. [less ▲]

Detailed reference viewed: 56 (9 ULg)
Full Text
Peer Reviewed
See detailRisk assessment tools for osteoporosis: scope and limits
Richy, Florent; Gourlay, M.; Ross, P. D. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 68-69

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailRational to use OSIRIS® (osteoporosis index of risk) to prescreen for osteoporosis in the general population
Richy, Florent; Gourlay, M.; Ethgen, Olivier ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 67-68

Detailed reference viewed: 30 (0 ULg)
Full Text
Peer Reviewed
See detailPhysical function is the most severely impaired health-related quality of life dimension during the aging process
Ethgen, Olivier ULg; Gosset, Christiane ULg; Richy, Florent et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 65

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailImpact of osteoarthritis and chronic back pain on health-related quality of life among patients on NSAIDS
Rabenda, Véronique ULg; Ethgen, Olivier ULg; Belaiche, Jacques ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 89-90

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailProspective evaluation of health-related quality of life in total hip and knee arthroplasties
Ethgen, Olivier ULg; Tancredi, Annalisa ULg; Brugneaux, C. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 66

Detailed reference viewed: 5 (2 ULg)
Full Text
Peer Reviewed
See detailDo patient with osteoporotic hip fracture recover their initial health-related quality of life?
Ethgen, Olivier ULg; Tancredi, Annalisa ULg; Jacques, J. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 66

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailEconomic evaluation of OSIRIS® (osteoporosis index of risk), a prescreening tool for prediction of osteoporosis risk, using decision trees and Markov models
Combescure, C.; Daures, J. P.; Chevallier, T. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 88

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailBMD in men: which normative data?
Richy, Florent; Gourlay, M.; Ethgen, Olivier ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 66-67

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailTime-dependent assessment of the gastrointestinal risk induced by low-dose aspirin intake: a meta-analysis
Richy, Florent; Bruyère, Olivier ULg; Ethgen, Olivier ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 95

Detailed reference viewed: 6 (1 ULg)
Full Text
Peer Reviewed
See detailBone mineral density and vertebral fractures in women who have discontinued hormone replacement therapy: a retrospective population-based study
Richy, Florent; Gourlay, M.; Neuprez, Audrey ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 67

Detailed reference viewed: 7 (3 ULg)
Full Text
Peer Reviewed
See detailControlled whole body vibration to decrease fall risk and improve health related quality of life in elderly patients
Bruyère, Olivier ULg; Wuidart, M. A.; di Palma, E. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 63

Detailed reference viewed: 28 (8 ULg)
Full Text
Peer Reviewed
See detailEvaluation of a campaign for osteoporosis screening in the general population: what is the follow-up given by general practitioners to a positive screening result?
Richy, Florent; Pire, G.; Maassen, P. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 67

Detailed reference viewed: 5 (2 ULg)
Full Text
Peer Reviewed
See detailEvaluation of an osteoporosis screening campaign in the general population: does misclassification by screening test impact on the perception of the campaign?
Richy, Florent; Pire, G.; Maassen, P. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 68

Detailed reference viewed: 16 (4 ULg)
Full Text
Peer Reviewed
See detailRisk assessment tools for osteoporosis: Scope and limits
Richy, Florent; Gourlay, Margaret; Ross, Philip D et al

in Arthritis and Rheumatism (2003, September), 48(number 9 (suppl.)), 215

Detailed reference viewed: 14 (4 ULg)
Full Text
Peer Reviewed
See detailStructural and symptomatic efficacy of glucosamine and chondroitine sulfate in osteoarthritis: a comprehensive meta-analysis
Richy, Florent Y; Bruyère, Olivier ULg; Ethgen, Olivier ULg et al

in Arthritis and Rheumatism (2003, September), 48(number 9 (suppl.)), 214

Detailed reference viewed: 23 (2 ULg)
Full Text
Peer Reviewed
See detailStructural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis - A comprehensive meta-analysis
Richy, Florent; Bruyère, Olivier ULg; Ethgen, Olivier ULg et al

in Archives of Internal Medicine (2003), 163(13), 1514-1522

Objective: To assess the structural and symptomatic efficacy of oral glucosamine sulfate and chondroitin sulfate in knee osteoarthritis through independent meta-analyses of their effects on joint space ... [more ▼]

Objective: To assess the structural and symptomatic efficacy of oral glucosamine sulfate and chondroitin sulfate in knee osteoarthritis through independent meta-analyses of their effects on joint space narrowing, Lequesne Index, Western Ontario MacMaster University Osteoarthritis Index (WOMAC), visual analog scale for pain, mobility, safety, and response to treatment. Methods: An exhaustive systematic research of randomized, placebo-controlled clinical trials published or performed between January 1980 and March 2002 that assessed the efficacy of oral glucosamine or chondroitin on gonarthrosis was performed using MEDLINE, PREMEDLINE, EMBASE, Cochrane Database of Systematic Reviews, Current Contents, BIOSIS Previews, Health-STAR, EBM Reviews, manual review of the literature and congressional abstracts, and direct contact with the authors and manufacturers of glucosamine and chondroitin. Inclusion, quality scoring, and data abstraction were performed systematically by 2 independent reviewers who were blinded to sources and authors. Conservative approaches were used for clear assessment of potential efficacy. Results: Our results demonstrated a highly significant efficacy of glucosamine on all outcomes, including joint space narrowing and WOMAC. Chondroitin was found to be effective on Lequesne Index, visual analog scale pain, mobility, and responding status. Safety was excellent for both compounds. Conclusions: Our study demonstrates the structural efficacy of glucosamine and indistinguishable symptomatic efficacies for both compounds. Regarding the relatively sparse data on glucosamine and joint space narrowing and the absence of data on structural effects of chondroitin, further studies are needed to investigate the relationship among time, dose, patient baseline characteristics, and structural efficacy for an accurate, disease-modifying characterization of these 2 compounds. [less ▲]

Detailed reference viewed: 23 (6 ULg)
Full Text
Peer Reviewed
See detailHealth-related quality of life and cost of ambulatory care in osteoporosis: how may such outcome measures be valuable information to health decision makers and payers?
Ethgen, Olivier ULg; Tellier, V.; Sedrine, W. B. et al

in BONE (2003), 32(6), 718-724

The objective was to quantify the outcome of osteoporosis (OP) in terms of health-related quality of life (HR-QOL) and cost of ambulatory care and to look at the association between these two outcomes ... [more ▼]

The objective was to quantify the outcome of osteoporosis (OP) in terms of health-related quality of life (HR-QOL) and cost of ambulatory care and to look at the association between these two outcomes variables. A cross-sectional health survey of 4800 Belgian individuals over the age of 45 years was used. Individuals having reported OP were retrieved and for each of them, at least two matched individuals for age, sex, residency location, and health insurance status were identified. All individuals were assessed with the SF-36. The two major health insurance providers furnished cost value for ambulatory care. HR-QOL and cost data were compared between the OP group and control group. Beta-coefficients from linear regression were calculated to give information on the relative importance of the association between each SF-36 dimensions and cost of ambulatory care. Of 4796 individuals appropriately surveyed, 221 (4.8%) reported OP. The control group included 651 individuals. The OP group experienced impaired HR-QOL compared to their matched counterparts, all the difference in mean or median SF-36 scores being significant at the level of P < 0.001. Osteoporotic respondents averaged 816 in cost of ambulatory care whereas controls averaged 579 (P < 0.001). When looking at detailed comparisons between categories of cost, costs in the OP group far exceeded those in the control group, all the differences being significant at the level of P < 0.001 except for home health nurse (P = 0.012). In the OP group, vitality dimensions played the most important role in the determination of cost (beta = -0.28, P < 0.001), followed by physical functioning (beta = -0.26, P < 0.01), general health, and social functioning (beta = -0.23, P < 0.01). This study evidences the burden of OP in terms of HR-QOL and cost of ambulatory care. Exploring the association between HR-QOL and cost show that mental dimension such as vitality can play an important role in the determination of cost. Conclusively, they should not be neglected in future management of OP. [less ▲]

Detailed reference viewed: 54 (7 ULg)