Strategies for rapid sample preparation and analysis of dioxins in biological samples

Conference (2002, March)

ISO17025 requirements: How to evaluate uncertainty for dioxin analysis in food and feed from validation data?

in Organohalogen Compounds (2002)

Comparison of HRGC-MS/MS and HRGC-HRMS results on environmental and food samples in some European laboraratories

in Organohalogen Compounds (2002)

Fast Clean-up for Polychlorinated Dibenzo-P-Dioxins, Dibenzofurans and Coplanar Polychlorinated Biphenyls Analysis of High-Fat-Content Biological Samples

in Journal of Chromatography. A (2001), 925(1-2), 207-21

A fast clean-up procedure for the low level analysis of polychlorinated dibenzo-p-dioxins. polychlorinated dibenzofurans and coplanar polychlorinated biphenyls in highly fatty biological matrices using ... [more ▼]

A fast clean-up procedure for the low level analysis of polychlorinated dibenzo-p-dioxins. polychlorinated dibenzofurans and coplanar polychlorinated biphenyls in highly fatty biological matrices using high capacity disposable multi-layer silica columns is presented. Results were compared with gel permeation chromatography for removal of lipids. Analytical criteria such as recovery rates, repeatability, reproducibility and robustness are evaluated through a broad range of biological matrices and reference materials analysis. The final proposed procedure for the complete analysis, including pressurized liquid extraction, Power-Prep system clean-up and GC-high-resolution MS analysis requires only 48 h, and allows the simultaneous preparation of up to 10 samples. [less ▲]

Levels and trends of PCDD/Fs and cPCBs in the Belgian food-stuffs one year after the "Dioxin Crisis

in Organohalogen compounds (2001), 51

Levels and Profile of PCDD/Fs and cPCBs in Belgian Breast Milk

in Organohalogen Compounds (2001), 52

Optimisation and Use of Tandem-in-Time Mass Spectrometry in Comparison with Immunoassay and Hrgc/Hrms for Pcdd/F Screening

in Chemosphere (2001), 43(4-7, May-Jun), 417-24

Rapid screening of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans using quadrupole ion storage tandem-in-time mass spectrometry (QISTMS) conjointly with polyclonal antibody ... [more ▼]

Rapid screening of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans using quadrupole ion storage tandem-in-time mass spectrometry (QISTMS) conjointly with polyclonal antibody immunoassay has been considered. The optimisation of the fragmentation of the parent ion in the trap has been completed. The analysis of fly ashes from a municipal waste incinerator contaminated at different levels has then been realised. Results obtained using QISTMS, HRMS and immunoassay are compared. [less ▲]

Contribution and Importance of Non-Ortho (Coplanar) PCBs for the I-TEQ Evaluation in "Dioxins Analysis" of Biological Matrices

in Organohalogen Compounds (2000)

Comparison between Immunoassay, GC/MS/MS and HRGC/HRMS on different fly ashes.

in Organohalogen Compounds (1999), 40

Supercritical fluid extraction of polychlorinated dibenzo-p-dioxins from fly ash: the importance of fly ash origin and composition on extraction efficiency

in Journal of Chromatography. A (1998), 819(1-2), 187-195

Supercritical fluid extraction (SFE) of polychlorinated dibenzo-p-dioxins (dioxins) from by ash samples, collected at different municipal waste incinerators, was investigated using supercritical CO2 and ... [more ▼]

Supercritical fluid extraction (SFE) of polychlorinated dibenzo-p-dioxins (dioxins) from by ash samples, collected at different municipal waste incinerators, was investigated using supercritical CO2 and compared to the classical Soxhlet extraction. Results were correlated to fly ash composition, which is strongly related to the fume purification system used in the incinerators. Fly ash collected at the bottom of the electrostatic precipitator is composed of dust coming from the combustion unit, but also of lime and eventually of activated charcoal injected in the fumes for acids and pollutants removal. When only lime is used for the fume purification, SFE of dioxins from fly ash leads to better results than Soxhlet extraction. The use of a binary cosolvent (trifluoroacetic acid in toluene) greatly increases the percentage recovery. When activated charcoal is used in conjunction with lime for the fume purification, SFE under classical extraction conditions is not powerful enough to extract dioxins, which are strongly adsorbed to the residual activated charcoal. (C) 1998 Elsevier Science B.V. All rights reserved. [less ▲]